Annual Tuberculosis Report - Illinois · 1,038).This is the first year in Illinois reporting...

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State of Illinois Rod R. Blagojevich, Governor Department of Public Health Eric E.Whitaker, M.D., M.P.H., Director Annual Tuberculosis Report - Illinois 2006

Transcript of Annual Tuberculosis Report - Illinois · 1,038).This is the first year in Illinois reporting...

Page 1: Annual Tuberculosis Report - Illinois · 1,038).This is the first year in Illinois reporting history that the number of foreign-born TB cases (54%) outnumbered the U.S.-born TB cases.

State of IllinoisRod R. Blagojevich, Governor

Department of Public HealthEric E. Whitaker, M.D., M.P.H., Director

Annual Tuberculosis Report - Illinois2006

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TABLE OF CONTENTS Page

Illinois Tuberculosis Control Report 2002-2006..........................................................................1 Introduction.............................................................................................................................1

Executive Summary ....................................................................................................................2 Table 1 Tuberculosis Cases by Jurisdiction and Regions, 2004-2005 ................................4

Appendix A – Illinois Data Summary..........................................................................................5 Table A1 Tuberculosis Cases reported between 2002 and 2006 by Jurisdiction....................5 Table A2 Tuberculosis Cases and Rates1 (per 100,000 Population), Illinois, 2002-2006 ......7 Figure A1 TB Morbidity, Number of Cases, Illinois, 1980-2006...........................................8 Figure A2 Distribution of Foreign-born Tuberculosis Cases, Illinois, 2002-2006 ..................8 Table A3 Number of Foreign-born Tuberculosis Cases (% of total cases), Illinois, 2002-

2006.....................................................................................................................9 Table A4 Tuberculosis Cases by Race/Ethnicity, Illinois, 2002-2006...................................9 Table A5 Tuberculosis Cases by Race/Ethnicity, Illinois, 2006..........................................10 Table A6 Tuberculosis Cases by Age Group, Illinois, 2002-2006 ......................................11 Table A7 Tuberculosis Cases by Age Group, Rates1 per 100,000 Population, Illinois, 2002-

2006...................................................................................................................11 Table A8 MDR1 and Isoniazid2 Drug Resistance in Culture Positive Cases, Illinois, 2002-

2006...................................................................................................................12 Table A9 Tuberculosis Cases by Directly Observed Therapy (DOT), Illinois, 2001-2005..13 Table A10 HIV and TB, 2002-2006.....................................................................................13 Table A11 Tuberculosis Cases by Risk Factors, 2002 – 2006 ..............................................14 Table A12 Tuberculosis Cases by Verification Criteria, 2002-2006.....................................14 Table A13 Tuberculosis Cases by Country of Origin, 2002-2006 ........................................15

Appendix B - References ..........................................................................................................16 Tuberculosis Case Definition for Public Health Surveillance .................................................16 Recommendations for Counting Reported Tuberculosis Cases ..............................................16

Appendix C – TB Regions ........................................................................................................17 Appendix D – Population Data..................................................................................................20

Table D1 Total Populations by Year for Illinois Jurisdictions ............................................20 Table D2 Population by Age Group, 2004 .........................................................................20

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Illinois Tuberculosis Control Report 2002-2006 Introduction Tuberculosis (TB) is a reportable disease in Illinois (suspect and confirmed cases). The sooner cases are reported to the local TB control authority, the sooner their personnel can begin investigations which may interrupt transmission of TB in the community. Delays in reporting may contribute to the spread of TB. The U.S. Centers for Disease Control and Prevention (CDC) has set national objectives to guide elimination of TB in the United States. Progress has been made toward meeting these objectives in Illinois (Table A1). In 2006, Illinois reported 569 TB cases and ranked fifth in the United States among states for the total number of cases reported (California 2,781; Texas 1,585; New York 1,274; and Florida 1,038).This is the first year in Illinois reporting history that the number of foreign-born TB cases (54%) outnumbered the U.S.-born TB cases. The incidence of TB reported by local Illinois TB authorities ranges from very low incidence (<1 case per year) of disease in rural counties, to high incidence (>400 cases per year) in the Chicago metropolitan area. The Illinois Department of Public Health TB Program is responsible for statewide surveillance, management of the Illinois TB case registry, and oversight of TB prevention and control activities conducted by local TB control authorities (local programs). The program continues to work with local TB control authorities to ensure accurate and timely reporting of the disease in Illinois. Surveillance data is used to direct public health efforts to identified high risk groups and geographic locations. Section staff assists local programs through the provision of Directly Observed Therapy (DOT) grants, assessment and identification of local problems, planning appropriate interventions, assistance with outbreaks, orientation and training of local staff, and promoting and facilitating networking with other programs. This report provides an overview of statewide TB morbidity. For more detailed information on the TB incidence for Illinois jurisdictions and the city of Chicago please refer to the following resources: National level detailed surveillance reports can be obtained from the CDC at: Division of Tuberculosis Elimination - Surveillance Reports Detailed surveillance report for the city of Chicago can be obtained through: Chicago Department of Public Health, TB Program Web Site CDPH TB Morbidity Reports

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Figure 1. Reported TB Cases and Rates Illinois, 1997-2006

0200400600800

10001200

1997

1998

1999

2000

2001

2002

2003

2004

2005

2006

Tota

l Cas

es

0

2

4

6

8

10

Rat

es/1

00,0

00

Total Rate

Executive Summary This is the first time in nine years that Illinois has observed an increase in the total number of tuberculosis (TB) cases (Figure 1). During 2006, a total of 569 TB cases were reported, representing a decrease of 3.6 percent from the 596 cases reported in 2005. The 2006 case rate for Illinois is 4.4 cases per 100,000 population, which remains below the 2006 national rate of 4.6 per hundred-thousand population. In 2006, the Suburban Cook County TB Sanitarium District reported 116 TB cases, 69 percent of which were foreign-born, compared 64 percent of which were foreign-born, reported in 2005 (Table 1 and Table A3). In 2006, the highest numbers of foreign cases were from three countries: India, Mexico and the Philippines. (The Suburban Cook County TB Sanitarium District reports cases from Cook County, outside the city of Chicago.) The Chicago TB Program reported 292 TB cases in 2006 compared with 333 cases in 2005, representing a decrease of 12.3 percent. The number TB cases reported among the foreign-born increased 23 percent from 101 in 2005 to 131 in 2006. The U.S.-born black non-Hispanic group continues to report the largest decrease of 26 percent from 154 in 2005 to only 114 cases in 2006. Between 2002 and 2006, Chicago did observe a 23.9 percent decline in number of cases and the rate of TB decreased from 13.3 per 100,000 population in 2002 to 10.8 cases per 100,000 population in 2006 (Figure A1 and Table A2). The decrease of cases in Chicago and suburban Cook County was offset by an increase in cases of 11.6 percent reported in Illinois outside of Cook County (Table 1). The largest increase of cases outside of Cook County was reported in the U.S.-born African American non-Hispanic population, which increased from 14 cases in 2005 to 21 cases in 2006. DuPage County reported the largest increase in the number of cases from 29 cases in 2005 to 44 cases in 2006. In 2006, 53.6 percent (N=305) cases were foreign-born, coming from 52 countries. Mexico (N=86), India (N=55) and the Philippines (N=39) which accounted for 60.0 percent of all foreign-born cases reported (Figure 2). The percentage of foreign-born cases increased from 23

Figure 2. Countries of Birth forForeign-born TB Cases in Illinois, 2006

Other23% Mexico

29%

India 18%

Somalia2%

Vietnam3%

Korea (Rep)3%

China5%

Philippines13%

Ethiopia2%

Poland2%

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percent (N=224) in 1997 to 54 percent (N=305) in 2006 (Figure 3). Among cases reported in 2006 within Illinois and outside of Chicago, 63.4 percent (N=175) were foreign-born. Among the total cases reported between 2002 and 2006, 35.1 percent were black non-Hispanic, 24.3 percent Hispanic, 24.0 percent Asian and 15.7 percent white non-Hispanic. During this same period, the percentage of cases reported among the Asian population increased slightly 1.3 percent, whereas the rates among the black non-Hispanic, Hispanic and white non-Hispanic populations decreased 32.3, 6.3 and 4.4 percent respectively. In 2006, the non-Hispanic black group reported the largest number of cases (N=186) among all the race/ethnicity categories (Table A4). Illinois demographic data shows that, from 2002 to 2006, the highest percentage (34.1 percent), was reported among the 25- to 44-year-old age group, whereas the highest rates per 100,000 persons was recorded among the 45 to 64 and 65 and older age groups (Tables A6 and A7). During this same period, cases were divided 59.3 percent male to 40.7 percent female. The rate of cases 18 to 64 years old reporting to be unemployed in the past 24 months increased from 38.5 percent in 2002 to 44.7 percent in 2006. Examining race and ethnicity data among cases reported in 2006 by region of the state yielded considerable differences. For example, in 2006 among the 184 cases African-American non-Hispanic TB cases reported, 71 percent were reported within Chicago and only 29 percent were outside of Chicago (Table A5). Among all cases reported in 2006, 65.4 percent (N=372) were pulmonary only, 27.4 percent (N=156) extra-pulmonary and 7.2 percent both (N=41). Following initial drug susceptibility testing one multi-drug resistant (MDR) case and no extensively drug-resistant TB (XDR-TB) cases were reported (Table A8). Between 2002 and 2006, there were 1,036 TB cases ages 25 to 44. Of these, 77.9 percent (N=807) reported a valid HIV status (positive, negative or indeterminate) and 11.7 percent (N=121) were HIV-positive. During this five-year period, reporting of HIV status for TB cases in this age group improved from a low of 69.5 percent in 2002 to a high of 89.1 percent in 2006 (Table A10). For all ages during the five-year period, the total number of HIV positive TB cases was 204 (6.7 percent). Among the 7,917 AIDS cases reported to the Illinois Department of Public Health (IDPH) during 2002-2006, TB (pulmonary and/or extra-pulmonary) was diagnosed in 194 (2.5 percent) of the cases.

Figure 3. Percentage TB CasesForeign-born vs. U.S.-born Illinois,

1997-2006

0%

20%

40%

60%

80%

100%1997199819992000200120022003200420052006

U.S.-bornForeign-born

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Table 1 Tuberculosis Cases by Jurisdiction and Regions, 2004-2005 Jurisdiction 2006 2005 % Change

Illinois 569 596 -4.5% Illinois Outside of Chicago (downstate) 277 263 5.3%

Illinois Outside Cook County 161 143 12.6%

Cook County 408 453 -9.9% City of Chicago 292 333 -12.3% Suburban Cook County 116 120 -3.3% DuPage County 44 29 51.7% Lake County 21 30 -30.0% Kane County 15 10 50.0% McHenry County 11 2 450.0% Will County 10 18 -44.4% St. Clair County 9 2 350.0% Winnebago County 5 7 -28.6% Jackson County 4 0 400.0% Madison County 2 7 -71.4% Champaign County 1 6 -83.3%

IDPH Regions Rockford 8 12 -33.3% Peoria 9 7 28.6% Edwardsville 15 11 36.4% Marion 9 7 28.6% Champaign 1 14 -92.9% West Chicago 105 91 15.4% Chicago (Cook) 408 453 -9.9%

TB Regions* North 99 83 19.3% Central 34 38 -10.5% South 24 21 14.3% * TB Regions are defined in appendix C.

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Appendix A – Illinois Data Summary Table A1 Tuberculosis Cases reported between 2002 and 2006 by Jurisdiction COUNTY 2002 2003 2004 2005 2006 Total Illinois, Total 680 633 569 596 569 3047

ADAMS 0 1 0 0 2 3

ALEXANDER 0 0 0 0 0 0 BOND 0 0 0 0 0 0 BOONE 1 1 2 1 3 8 BROWN 0 0 0 0 0 0 BUREAU 0 0 0 0 1 1

CALHOUN 0 0 0 0 0 0 CARROLL 0 0 0 0 0 0 CASS 0 0 0 2 2 4 CHAMPAIGN 10 4 3 6 1 24 CHRISTIAN 1 0 0 0 0 1

CLARK 0 0 0 1 0 1 CLAY 0 0 2 0 0 2 CLINTON 0 0 0 0 0 0 COLES 0 0 0 0 0 0 COOK 512 462 399 453 408 2234

CHICAGO 382 339 308 333 292 1654 SUBURBAN COOK 130 123 91 120 116 580

CRAWFORD 0 0 1 0 0 1 CUMBERLAND 0 0 0 0 0 0 DEKALB 2 1 2 4 0 9

DEWITT 0 0 0 0 0 0 DOUGLAS 0 0 0 0 1 1 DUPAGE 32 62 47 29 44 214 EDGAR 0 0 0 0 0 0

EDWARDS 0 0 0 0 0 0 EFFINGHAM 0 0 0 2 0 2 FAYETTE 1 0 0 1 1 3 FORD 1 0 0 0 0 1 FRANKLIN 1 1 2 1 0 5

FULTON 0 0 0 0 1 1 GALLATIN 1 0 0 0 0 1 GREENE 0 0 0 0 0 0 GRUNDY 0 0 0 0 2 2 HAMILTON 0 0 0 0 0 0

HANCOCK 0 0 0 0 0 0 HARDIN 1 0 0 0 0 1 HENDERSON 0 0 0 0 0 0 HENRY 0 0 0 0 0 0 IROQUOIS 0 0 0 2 1 3

JACKSON 1 0 1 0 4 6 JASPER 0 0 0 0 0 0 JEFFERSON 1 0 2 1 1 5

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COUNTY 2002 2003 2004 2005 2006 Total JERSEY 0 0 0 0 1 1

JO DAVIESS 0 0 0 0 0 0 JOHNSON 0 0 0 0 0 0 KANE 15 18 13 10 15 71 KANKAKEE 1 3 1 2 2 9 KENDALL 0 0 1 0 0 1

KNOX 0 2 1 0 1 4 LAKE 19 30 24 30 21 124 LASALLE 1 0 0 1 1 3 LAWRENCE 0 2 1 0 0 3 LEE 1 0 1 0 0 2

LIVINGSTON 1 0 0 0 1 2 LOGAN 0 0 0 0 0 0 MCDONOUGH 0 0 0 0 0 0 MCHENRY 7 0 7 2 11 27 MCLEAN 3 3 0 1 5 12

MACON 1 2 0 3 0 6 MACOUPIN 1 0 1 0 0 2 MADISON 2 5 6 7 2 22 MARION 0 0 2 0 1 3

MARSHALL 0 0 0 0 0 0 MASON 1 0 0 0 0 1 MASSAC 2 0 1 0 0 3 MENARD 0 0 0 0 0 0 MERCER 0 0 0 0 0 0

MONROE 0 0 1 0 0 1 MONTGOMERY 0 0 2 0 0 2 MORGAN 1 0 0 0 0 1 MOULTRIE 0 0 0 0 0 0 OGLE 0 0 0 0 0 0

PEORIA 8 3 0 3 0 14 PERRY 2 0 0 0 0 2 PIATT 1 0 0 0 0 1 PIKE 1 0 0 0 0 1 POPE 0 0 0 0 0 0

PULASKI 0 0 0 0 0 0 PUTNAM 0 0 0 0 0 0 RANDOLPH 0 0 1 0 0 1 RICHLAND 1 0 0 1 0 2 ROCK ISLAND 2 7 3 1 0 13

ST. CLAIR 11 8 5 2 9 35 SALINE 0 0 1 1 0 2 SANGAMON 1 1 5 2 3 12 SCHUYLER 0 0 0 0 1 1

SCOTT 1 0 0 0 0 1 SHELBY 0 0 0 0 0 0 STARK 0 0 0 0 0 0

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COUNTY 2002 2003 2004 2005 2006 Total STEPHENSON 0 1 1 0 0 2

TAZEWELL 1 0 1 0 0 2 UNION 1 0 0 0 0 1 VERMILION 2 0 0 1 2 5 WABASH 1 0 1 0 0 2 WARREN 0 0 0 0 0 0

WASHINGTON 0 0 1 0 0 1 WAYNE 0 0 0 0 0 0 WHITE 2 0 0 0 0 2 WHITESIDE 0 0 0 0 0 0 WILL 16 9 15 18 10 68

WILLIAMSON 1 1 3 0 2 7 WINNEBAGO 7 3 9 7 5 31 WOODFORD 0 2 0 0 0 2

STATE-AT-LARGE 0 1 0 1 4 6

Table A2 Tuberculosis Cases and Rates1 (per 100,000 Population), Illinois, 2002-2006

Year 2002 2003 2004 2005 2006

Illinois

680 (5.4)

633 (5.0)

569 (4.5)

596 (4.7)

569 (4.4)

Illinois Outside of Cook County

168 (2.3)

171 (2.3)

170 (2.3)

143 (1.9)

160 (2.1)

Cook County

512 (9.5)

462 (8.6)

399 (7.5)

453 (8.5)

408 (7.7)

Illinois Outside of Chicago

298 (3.1)

294 (3.0)

261 (2.7)

263 (2.7)

277 (2.8)2

Suburban Cook County

130 (5.3)

123 (5.0)

91 (3.7)

120 (4.9)

116 (4.7)2

City of Chicago

382 (13.2)

339 (11.8)

308 (10.7)

333 (11.7)

292 (10.3)2

1Source: U.S. Census Bureau. Illinois rates based on 2002 -2006 population estimates from the U.S. Census Bureau. Previous reports used 2000 census population to calculate rates for all five years. See Appendix D for population numbers

2The 2006 population estimate was not available for Chicago at the time of this report. Rates were calculated using 2005 population estimate for Chicago and Illinois.

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Figure A1 TB Morbidity, Number of Cases, Illinois, 1980-2006

Figure A2 Distribution of Foreign-born Tuberculosis Cases, Illinois, 2002-2006

020406080

100120140160180200

2002 2003 2004 2005 2006

DownstateCity of Chicago

0

200

400

600

800

1000

1200

1400

1600

180019

80

1981

1982

1983

1984

1985

1986

1987

1988

1989

1990

1991

1992

1993

1994

1995

1996

1997

1998

1999

2000

2001

2002

2003

2004

2005

2006

Illinois Ill. Excluding Cook County Suburban Cook County Ill. Excluding Chicago City of Chicago

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Table A3 Number of Foreign-born Tuberculosis Cases (% of total cases), Illinois, 2002-2006 Year 2002 2003 2004 2005 2006 Total

Illinois 38.9% (265/680)

43.1% (273/633)

40.4% (230/569)

44.8% (267/596)

53.8% (305/569)

44.0% 1340/3047

Illinois Outside of Cook County

50.6% (85/168)

60.2% (103/171)

59.7% (101/170)

61.5% (88/143)

59.4% (95/160)

58.1% (472/812)

Cook County 35.1% (180/512)

36.8% (170/462)

46.7% (127/399)

39.5% (179/453)

52.0% (212/408)

38.9% (868/2243)

Illinois Outside of Chicago

57.4% (171/298)

62.2% (183/294)

59.0% (154/261)

63.1% (166/263)

63.8% (176/277)

61.1% (850/1393)

Suburban Cook County

66.2% (86/130)

65.0% (80/123)

58.2% (53/91)

65.0% (78/120)

69.0% (80/116)

65.0% (377/580)

City of Chicago

24.6% (94/382)

26.6% (90/339)

24.0% (74/308)

30.3% (101/333)

44.9% (131/292)

29.6% (490/1654)

Table A4 Tuberculosis Cases by Race/Ethnicity, Illinois, 2002-2006

2002 (%)

2003 (%)

2004 (%)

2005 (%)

2006 (%) Total

Total 680 633 569 596 569 3047

White, Non-Hispanic 128 (18.8)

93 (14.7)

88 (15.5)

80 (13.4)

89 (15.6)

478 (15.7)

Black, Non-Hispanic 246 (36.2)

231 (36.5)

188 (33.0)

218 (36.6)

186 (32.7)

1069 (35.1)

Hispanic 152 (22.4)

147 (23.2)

160 (28.1)

138 (23.1)

143 (25.1)

740 (24.3)

American Indian or Alaskan Native

3 (0.4)

4 (0.6)

2 (0.4)

2 (0.3)

0 (0.0)

11 (0.4)

Asian 149 (21.9)

154 (24.3)

125 (22.0)

151 (25.3)

151 (26.5)

730 (24.0)

Native Hawaiian or Pacific Islander1 NA 1

(0.2) 1

(0.2) 2

(0.3) 0

(0.0) 4

(0.1)

Multiple Races Indicated2 NA 2 (0.3)

5 (1.1)

5 (0.8)

0 (0.0)

11 (0.4)

Unknown 2 (0.3)

1 (0.2)

0 (0.0)

0 (0.0)

0 (0.0)

3 (0.1)

1 Native Hawaiian or Pacific Islander was included in Asian before 2003. 2 Multiple race reporting was not possible with the pre-2003 RVCT.

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Table A5 Tuberculosis Cases by Race/Ethnicity, Illinois, 2006

Total Cases

White, Non-

Hispanic (%)

Black, Non-

Hispanic (%)

Hispanic(%)

American Indian or Alaskan Native

(%) Asian (%)

Native Hawaiian or Pacific Islander

(%)

Multiple Race

Indicated (%)

Unknown (%)

Illinois 569 89 (15.6)

186 (32.7)

143 (25.1)

0 (0.0)

151 (26.5)

0 (0.0)

0 (0.0)

0 (0.0)

Illinois Outside of Cook County

161 40 (24.8)

35 (21.7)

39 (24.2)

0 (0.0)

46 (28.8)

1 (0.6)

0 (0.0)

0 (0.0)

Cook County 408 49

(12.0) 150

(36.7) 104

(25.5) 0

(0.0) 105

(25.7) 0

(0.0) 0

(0.0) 0

(0.0) Illinois Outside of Chicago

277

59 (21.3)

54 (19.5)

64 (23.1)

0 (0.0)

99 (35.7)

1 (0.4)

0 (0.0)

0 (0.0)

Suburban Cook County

116 19 (16.4)

19 (16.4)

25 (21.5)

0 (0.0)

53 (45.7)

0 (0.0)

0 (0.0)

0 (0.0)

City of Chicago 292 30

(10.3) 131

(44.9) 79

(27.1) 0

(0.0) 52

(17.8) 0

(0.0) 0

(0.0) 0

(0.0)

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Table A6 Tuberculosis Cases by Age Group, Illinois, 2002-2006 Age Group

Total Cases All

Ages

0-4 (%)

5-14 (%)

15-24 (%)

25-44 (%)

45-64 (%)

65+ (%)

2002 680 25 (3.7)

19 (2.8)

76 (11.2)

226 (33.2)

199 (29.3)

135 (19.9)

2003 633 25 (4.0)

19 (3.0)

71 (11.2)

228 (36.0)

182 (28.8)

108 (17.0)

2004 569 21 (3.7)

19 (3.3)

54 (9.5)

206 (36.2)

174 (30.6)

95 (16.7)

2005 596 22 (3.7)

24 (4.0)

63 (10.6)

203 (34.1)

180 (30.2)

104 (17.5)

2006 569 29 (5.1)

15 (2.6)

52 (9.1)

175 (30.8)

182 (32.0)

116 (20.4)

Total 3047 122 (4.0)

96 (3.2)

316 (10.4)

1038 (34.1)

917 (30.1)

558 (18.3)

Table A7 Tuberculosis Cases by Age Group, Rates1 per 100,000 Population, Illinois, 2002-2006

Age Group Rates per 100,0001 0-4 5-14 15-24 25-44 45-64 65+

2002 2.7 1.0 4.2 6.1 6.6 8.8 2003 2.7 1.0 3.9 6.1 6.0 7.1 2004 2.3 1.0 3.0 5.5 5.8 6.2 2005 2.4 1.3 3.5 5.4 6.0 6.8 2006 3.2 0.8 2.9 4.7 6.0 7.6

1Source: U.S. Census Bureau. Illinois rates based on 2004 population estimates from the U.S. Census Bureau. Previous reports used 2000 census population to calculate rates for all five years. See Appendix D for population numbers.

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Table A8 MDR1 and Isoniazid2 Drug Resistance in Culture Positive Cases, Illinois, 2002-2006 Year 2002 2003 2004 2005 2006

INH Resistant

3.8% (20/524)

6.3% (30/474)

6.7% (28/415)

7.5% (33/442)

6.5% (27/413)

Illinois

MDR Resistant

1.3% (6/524)

0.9% (3/474)

1.6% (5/415)

0.0% (0/442)

0.2% (1/413)

INH Resistant

1.6% (2/123)

3.5% (6/123)

8.4% (10/119)

11.2% 12/108

1.9% (3/114)

Illinois Outside of Cook County

MDR Resistant

0.8% (1/123)

0.86% (1/123)

1.6% (2/119)

0.0% 0/110

0.0% (0/114)

INH Resistant

4.5% (18/401)

6.8% (24/3514)

6.1% (21/296)

6.3% 21/341

8.0% (24/299)

Cook County

MDR Resistant

1.2% (5/401)

0.60% (2/3514)

0.0% (0/296)

0.0% (0/341)

0.3 (1/299)

INH Resistant

4.3% (10/230)

6.6% (14/2114)

5.9% (11/188)

8.2% (17/207)

4.5% (9/201)

Illinois Outside of Chicago

MDR Resistant

1.3% (3/230)

0.9% (2/2114)

1.6% (3/188)

0.0% (0/209)

0.5% (1/201)

INH Resistant

7.5% (8/108)

9.1% (8/88)

1.4% (1/69)

5.1% (5/99)

6.9% (6/87)

Suburban Cook County

MDR Resistant

1.9% (2/108)

1.1% (1/88)

1.4% (1/69)

0.0% (0/99)

1.1% (1/87)

INH Resistant

3.4% (10/294)

6.1% (16/263)

7.5% (17/227)

6.8% (16/235)

8.5% (18/212)

Chicago

MDR Resistant

1.0% (3/294)

0.4% (1/263)

0.9% (2/227)

0.0% (0/235)

0.0% (0/212)

1 Isolates resistant to at least isoniazid and rifampin. 2 Isoniazid resistant cases also may be resistant to other drugs, while being susceptible to rifampin. All years data updated May 9, 2007.

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Table A9 Tuberculosis Cases by Directly Observed Therapy (DOT), Illinois, 2001-2005

DOT

Year Total Cases

Cases Eligible

for DOT1

Totally Self Administered

(%)

Totally DOT (%)

Both DOT and SA

(%) Total (%)

Unknown or Missing

(%)

2001 707 684 209

(30.5) 368

(53.8) 106

(15.5) 474

(69.3) 1

(0.1)

2002 680 653 212

(32.4) 346

(53.0) 96

(14.7) 442

(67.6) 0

(0.0)

2003 633 605 148

(24.5) 327

(54.1) 127

(21.0) 454

(75.0) 3

(0.5)

2004 569 546 132

(24.2) 299

(54.8) 105

(19.2) 404

(74.0) 0

(0.0)

2005 596 574 173

(30.1) 306

(53.3) 90

(15.7) 396

(69.0) 5

(0.9)

Total 3185 3062 874

(28.5) 1646 (53.8)

524 (17.1)

2170 (70.9)

9 (0.3)

1 Includes cases alive at diagnosis with an initial drug regimen of one or more drugs prescribed. Table A10 HIV and TB, 2002-2006

Year Total Cases

Total Cases Ages 25-44 years

(%) Valid Response1

(%)

Total HIV Positive2

(%)

2002 680 226

(33.2) 157

(69.4) 30

(13.2)

2003 633 228

(36.0) 162

(71.0) 28

(12.2)

2004 569 206

(35.9) 162

(78.6) 22

(10.7)

2005 596 202

(33.8) 171

(84.2) 23

(11.2)

2006 569 174

(30.6) 155

(89.1) 18

(10.3)

Total 3,047 1,036 (34.1)

807 (77.9)

121 (11.7)

1 Valid response includes (0) negative, (1) positive or (2) indeterminate. 2 Positive results are based on either medical documentation or patient history.

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Table A11 Tuberculosis Cases by Risk Factors, 2002 – 2006

Year Total Cases

Correctional Facility1

(%) Homeless2

(%)

Long-Term Care Facility3

(%)

Injection Drug Use4

(%)

2002 680 20

(2.9) 31

(4.5) 17

(2.5) 16

(2.3)

2003 633 7

(1.1) 23

(3.6) 9

(1.4) 6

(1.0)

2004 569 10

(1.8) 22

(3.9) 13

(2.3) 6

(1.1)

2005 596 14

(2.4) 23

(3.9) 11

(1.9) 5

(0.8)

2006 569 21

(3.7) 27

(4.7) 12

(2.1) 9

(1.6)

Total 3047 72

(2.4) 126 (4.1)

62 (2.0)

42 (1.4)

1 Resident of correctional facility at time of diagnosis

2 Homeless in past 12 months 3 Resident of long-term care facility at time of diagnosis 4 Injection drug use in past 12 months Table A12 Tuberculosis Cases by Verification Criteria, 2002-2006 Year Total

Cases1 Culture

Confirmed (%)

Smear Positive

(%)

Clinical Definition

(%)

Provider Diagnosis

(%) 2002 679 531

(78.2) 5

(0.7) 110

(16.2) 33

(4.9) 2003 630 484

(76.8) 5

(0.8) 89

(14.1) 52

(8.3) 2004 567 430

(75.8) 11

(1.9) 71

(12.5) 55

(9.7) 2005 596 452

(75.8) 5

(0.8) 54

(9.1) 85

(14.3) 2006 569 440

(77.3) 5

(0.9) 56

(9.9) 68

(12.0) Total 3041 2337

(76.8) 31

(10.1) 380

(12.5) 293 (9.6)

1 Current data as of May 4, 2007, was used to populate this table. Row totals do not reflect the total number of counted cases for that year, but rather reflect the number of currently known cases at that time.

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Table A13 Tuberculosis Cases by Country of Origin, 2002-2006 Country of Origin 2002 2003 2004 2005 2006 Total Mexico 77 73 79 70 86 385 India 61 53 43 56 55 268 Philippines 32 44 37 32 39 184 China 5 12 8 10 15 50 Poland 8 6 7 13 6 40 Vietnam 6 8 5 8 10 37 Korea, Republic Of 10 6 5 7 9 37 Ethiopia 6 2 1 8 6 23 Pakistan 9 2 3 4 3 21 Nigeria 5 9 1 2 2 19 Ecuador 2 4 5 3 2 16 Guatemala 1 4 2 3 4 14 Somalia 1 0 1 4 7 13 Bosnia And Hercegovina 3 3 2 1 2 11 Peru 0 1 4 3 1 9 Romania 2 1 1 1 4 9 Honduras 2 1 1 2 2 8 Thailand 1 2 1 3 1 8 Haiti 1 3 0 3 1 8 All Other Nations 33 39 24 34 50 180

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Appendix B - References Tuberculosis Case Definition for Public Health Surveillance see CDC reference: http://www.cdc.gov/tb/surv/surv2002/PDF/AppendixB.pdf Recommendations for Counting Reported Tuberculosis Cases see CDC reference: http://www.cdc.gov/tb/surv/surv2002/PDF/AppendixC.pdf

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Appendix C – TB Regions TB Regions are divided as follows: Northern TB Region includes all of IDPH Rockford and West Chicago Region except Grundy, Kankakee and Will counties. Central TB Region includes all of IDPH Peoria and Champaign Region plus Grundy, Kankakee, and Will counties from West Chicago Region and; excludes Macon, Moultrie and Shelby counties. Southern TB Region includes all of IDPH Edwardsville and Marion Region including Macon, Moultrie and Shelby counties from Champaign Region.

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Appendix D – Population Data Table D1 Total Populations by Year for Illinois Jurisdictions 2002 2003 2004 2005 2006 Illinois 12,595,003 12,649,778 12,713,548 12,765,427 12,831,970 Illinois Outside of Cook County 7,225,361 7,300,872 7,387,279 7,461,484 7,543,315

Cook County 5,369,642 5,348,906 5,326,269 5,303,943 5,288,655 Illinois Outside of Chicago 9,693,703 9,764,778 9,827,048 9,922,909 9,922,9091

Suburban Cook County 2,468,342 2,463,906 2,439,769 2,461,425 2,461,4251

City of Chicago 2,901,300 2,885,000 2,886,500 2,842,518 2,842,5181 Table D2 Population by Age Group, 2004

0-4 5-14 15-24 25-44 45-64 +65 913,089 1,847,648 1,823,661 3,735,259 3,009,507 1,527,160

1 The 2006 population estimate was not available for Chicago at the time of this report. Rates were calculated using 2005 population estimate for Chicago and Illinois.

2 Age group data taken from the Census Bureau 2004 Population Estimate.