ANNUAL REPORT 2016

2016 was an exciting and productive year for TSRC. Our programming included 40 Workshops, four Conferences, and one Summer School, engaging 1400 scientists from 30 countries and representing a remarkable diversity of molecular science. In addition, important steps were taken to evaluate the current state of our organization, enhance our governance structure, and plan for TSRC’s future.

CREATION OF GENERAL MEMBERS OF TSRC: TSRC’s governance structure was enhanced through the creation of the TSRC General Members. This group of over 70 scientists is designed to reflect the remarkable variety of molecular science explored in TSRC programming. The General Members represent TSRC’s diverse community of scientists, serving as an oversight and nominating body to the Board of Directors.

STRATEGIC PLANNING INITIATIVE: Our organization engaged in a rigorous year-long planning effort led by the Strategic Planning Working Group, charged with evaluating the greatest challenges and opportunities facing our organization and defining a plan to protect and enhance our organization in the near and long term. Recommendations of the group were shared with the General Members for comment and discussed by the Board at a retreat in December 2016. The resulting strategic plan calls for preserving the unique qualities that define the TSRC experience and for enhancing the diversity of programming while carefully managing future growth.

SECURING OUR HOME IN TELLURIDE: Since 1984, our organization has contributed to the economy and culture of the Telluride community through our TSRC Town Talks lecture series, the active participation of our scientists in science education and outreach hosted by the Pinhead Institute and Telluride Schools, and contributing economically to local businesses in Telluride and Mountain Village (currently estimated to be $5-7M annually). Recently, we have launched a capital campaign to support the creation of a permanent facility that will significantly expand TSRC’s ability to host workshops outside the traditional summer season and secure the organization’s headquarters and future operations in the Town of Telluride.

In closing, I would like to thank the members of our devoted Board and Staff for providing the leadership and support that is so critical to the successful operation of our organization. Special thanks to Joan-Emma Shea (University of California, Santa Barbara) for her exceptional contributions over two terms of Board service. We were pleased to welcome new Board members Nancy Levinger (Colorado State University), Ann McDermott (Columbia University), and Jim Skinner (University of Chicago). I encourage all members of our community to reach out to our Board, General Members, and Staff to share ideas that might enhance our programming and operations.

We can look forward to an exciting future for TSRC as we work to preserve and enhance the unique qualities that make TSRC a leading international center for the advancement of molecular science.

My best,

John E. Straub TSRC President, Boston University

Advancing our understanding of science, at the molecular level, drives innovation in everything from new and improved materials, to detection and treatment of disease, to the capture and storage of energy, to our understanding of earth systems and the universe. TSRC scientists are pioneering the next big advances in science and technology.

Photo: Jackie Ricciardi

TSRC is committed to facilitating the generation of ideas and research partnerships that expand the frontiers of science through an environment that is supportive and collaborative. TSRC will carefully manage any growth to maintain the unique qualities of TSRC workshops, schools, and conferences.

In 2016, TSRC conducted its first strategic planning effort. All stakeholders overwhelmingly agreed that the quality of programming could not be compromised for the sake of growth. The strategic planning process allowed TSRC scientists to articulate the value and uniqueness of TSRC’s brand: The small, friendly, intimate, and naturally inspiring environment fosters communication, collaboration, and sense of community. These qualities nurture the advancement of science. As TSRC moves forward, it plans to expand and diversify its programming to support the newest and most innovative areas of research. The organization also seeks to establish a permanent facility to support its year-round programming and establish a home that optimizes free thinking and collaboration.

Chaired by James Skinner of the University of Chicago and Audrey Marnoy, a TSRC Board member, the working group included Irene Burghardt of the University of Frankfurt, Ken Jordan of the University of Pittsburg, Doug Tobias of the University of California, Irvine, and Tamar Schlick of New York University. Board members on the committee were Joan-Emma Shea of the University of California, Santa Barbara, Ann McDermott and David Reichman of Columbia University, Miles Cook of Bain Consulting, and Mark Kozak, TSRC Executive Director.

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Pia Adelroth, Stockholm UniversityIvan Aprahamian, Dartmouth UniversityThomas Beck, University of CincinnatiAlexander Benderski, University of Southern CaliforniaR. Stephen Berry, TSRC Co-founder, Honorary Lifetime General Member, University of ChicagoEric Bittner, University of HoustonChristopher Cheatum, University of IowaChristine Chow, Wayne State UniversityRobert Coalson, University of PittsburghRonald Cohen, University of California, BerkeleyJames Crutchfield, University of California, DavisJaime Fernandez-Baca, Oak Ridge National LaboratoryClaudia Filippi, University of TwenteJohn Frederick, Honorary Lifetime General Member, The University of Texas at San AntonioBertrand Garcia-Moreno, Johns Hopkins UniversityFranz Geiger, Northwestern UniversityWilliam H. Green, Massachusetts Institute of TechnologyMarilyn Gunner, City College of New YorkTeresa Head-Gordon, University of California, BerkeleyMichael Heaven, Emory UniversityMy Helms, University of UtahGraeme Henkelman, The University of Texas at AustinRigoberto Hernandez, Georgia Institute of TechnologyRyan Hunter, University of MinnesotaChristine Isborn, University of California, MercedKenneth Jordan, Honorary Lifetime General Member, University of PittsburghMichael Kellman, Honorary Lifetime General Member, University of OregonTom Kleyman, University of PittsburghTamiki Komatsuzaki, Hokkaido UniversitySonia M. Kreidenweis, Colorado State University

Timothy Lodge, University of MinnesotaDmitrii Makarov, The University of Texas at AustinThomas Markland, Stanford UniversityJames McCusker, Michigan State UniversityJeetain Mittal, Lehigh UniversityValeria Molinero, University of UtahFrans Mulder, University of AarhusAmy Mullin, University of MarylandJean-Philip Piquermal, Sorbonne UniversityWilliam Poirier, Texas Tech UniversityJanett Prehl, Technische Universitat ChemnitzSteven Presse, Indiana University–Purdue University IndianapolisArvind Ramanathan, Oakridge National LaboratoryWilliam Reinhardt, Honorary Lifetime General Member, University of WashingtonChad Risko, University of KentuckySylvie Roke, Ecole Polytechnique Federale De LausannePeter Salamon, TSRC Co-founder, Honorary Lifetime General Member, San Diego State UniversityWolfram Sander, Ruhr-Universitat BochumGustavo Scuseria, Rice UniversityEdwin (Ned) Sibert, Honorary Lifetime General Member, University of Wisconsin-MadisonCarlos Silva, University of MontrealDean Tantillo, University of California, DavisWard Thompson, University of KansasMichael Thoss, University of ErlangenDoug Tobias, University of California, IrvineEdward Valeev, Virginia TechTroy Van Voorhis, Massachusetts Institute of TechnologyHolger Waalkens, University of GroningenDavid Wales, University of CambridgeRobert Walker, Montana State UniversityMartin Weik, Institut de Biologie Structurale

In 2016, TSRC created the General Members to strengthen the voice of TSRC scientists in governance and planning. Over the course of the year, the General Members played an important role in the strategic planning effort. TSRC is pleased to have this broad engagement of scientists in helping to shape the organization’s future.

“TSRC is a breath of fresh air when it comes to its engagement with scientists up there in the mountains of Colorado. The organization was able to afford early recognition to this relatively new line of research and provide the ideal meeting place for the pioneers from all around the world to come together for a week, first of all in 2014 and then again in 2016, and inform one another, swap ideas, and establish collaborations.”– Sir Fraser Stoddart, 2016 Nobel Prize in Chemistry

Sir J. Fraser Stoddart of Northwestern University and Bernard Feringa of the University of Groningen were two of the three winners of the 2016 Nobel Prize in Chemistry for their work in designing and synthesizing “molecular machines.”

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Bernard Feringa photo ©University of Groningen

WORKSHOPSJANUARY 11-15, 2016New Challenges for Theory in Chemical Dynamics Millard Alexander and Ward Thompson

JUNE 06-10, 2016Mass-Independent Fractionation of Sulfur Isotopes: Possible Molecular Origins Bill Poirier and Hua Guo

JUNE 21-25, 2016Nonlinear Optics at Interfaces Franz M. Geiger and Alexander V. BenderskiiChallenges in RNA Structural Modeling and Design Tamar Schlick and Anna Marie PyleThermal Transport at the Nanoscale Jonathan Malen and Dan GezelterActivation of Small Molecules A.S. Borovik, Charles G. Riordan, and William B Tolman

JUNE 23-JULY 01, 2016Information Engines at the Frontiers of Nanoscale Thermodynamics Sebastian Deffner, Korana Burke, Tommy Byrd, and Jim Crutchfield

JUNE 27-JULY 01, 2016Aerosols and Clouds: Connections from the Laboratory to the Field to the Globe Sonia Kreidenweis, Annica Ekman, Graham Feingold, and Ken CarslawHigh Temperature Energy Conversion: Electrochemical Oxidation and Reduction Mechanisms Rob Walker, Bryan Eichhorn, and Jeff OwrutskyElectronic and Magnetic Properties of Chiral Structures and their Assemblies Ron Naaman, David Beratan, Spiros Skourtis, and David WaldeckCondensed Phase Dynamics Eran Rabani and David R. ReichmanProtein and Peptide Interactions in Cellular Environments Joan-Emma Shea and Michael Feig

JULY 04-08, 2016Charge and Energy Transfer in Photoreactions and Photodynamics Dmitri Kilin, Sebastian Fernandez Alberti, and Kirill VelizhaninComplexity in the Chemistry and Physics of Lipid Membranes Rob Walker, Colin Bain, and John SeddonNon-Equilibrium Statistical Physics: From Molecular Materials to Theoretical Engineering. Honoring Professor Vladimir Chernyak 60th Birthday Andrei Piryatinski, Sergei Tretiak, and Michael Chertkov Energy and Movement in Coherent Chemical Systems Jeffrey J. Rack and Leonard (Len) MacGillivray

JULY 12-16, 2016Proton Transfer in Biology Pia Adelroth and Christopher MaupinIons in Solution: Biology, Energy, and Environment Thomas Beck, Susan Rempe, and Lawrence PrattHydrophobicity: From Theory, Simulation, to Experiment Dor Ben Amotz and Amish PatelMany-Body Interactions: From Quantum Mechanics to Force Fields Kenneth Jordan and Jean-Philip PiquermalElectronic and Structural Dynamics in Hybrid Perovskites: Theory Meets Experiment Jacky Even and Sergei TretiakSingle Molecule Workshop: Theory Meets Experiment Jianshu Cao and Ken Ritchie

JULY 18-22, 2016Molecular Recognition and the Chemical Senses Eric Bittner and Andrew HorsfieldSpectroscopy and Dynamics on Multiple Potential Energy Surfaces Michael Heaven, Anne McCoy, Scott Reid, and Trevor SearsOrganic Particles in the Atmosphere: Formation, Properties, Processing, and Impact Chris Cappa and Yinon RudichNew Insights Into Gas-Phase Atmospheric Chemistry Delphine Farmer and Ron CohenInterfacial Molecular and Electronic Structure and Dynamics Sylvie Roke and Dor Ben Amotz

JULY 25-29, 2016Nucleic Acid Chemistry Scott Silverman and Sheila DavidCoarse-Grained Modeling of Structure and Dynamics of Biomacromolecules Andrzej Kloczkowski, Robert L. Jernigan, Florence Tama, and Ruth NussinovInterfacial Chemistry and Charge Transfer for Energy Storage and Conversion Don Siegel, Graeme Henkelman, and Keith StevensonEpithelial Physiology and Cell Biology Thomas Kleyman, John Cuppoletti, My Helms, and Peter SynderNuclear Pore Complexes and Smart Polymers Rob Coalson and Anton Zilman

JULY 25-28, 2016Advanced Methods for De Novo Prediction of Chemical Reaction Networks Jim Pfaendtner and William H. Green

AUGUST 01-04, 2016Biogeochemistry and Redox Transformations of Iron Andreas Kappler and Alexis Templeton

AUGUST 01-05, 2016Chromatin Structure and Dynamics Yawen Bai and Gregory BowmanAccelerating Reaction Discovery Kay M. Brummond, Dean Tantillo, and Matthias McIntoshRadicals in the Rockies Wolfram SanderEnabling Technology for Reactions and Processes Greg Dudley, Jason Hein, and Nicola PohlRecent Progress in Numerical Green’s Functions Methods in Physics and Chemistry Dominika Zgid and Emanuel GullSolution Based Synthesis of Nanomaterials and Their Organization for Hybrid Device Structures James J. Watkins, Cyril Aymonier, and Tadafumi Adschiri

SUMMER SCHOOLSJUNE 21-25, 2016TSRC Summer School on Fundamental Science for Alternative Energy Victor Batista and Gary Brudvig

CONFERENCESAPRIL 03-08, 2016Protein Dynamics TSRC Conference at Les Houches, France Arwen Pearson, Paul Schanda. Douglas Tobias, and Martin Weik

JUNE 01-05, 2016Low-scaling and Unconventional Electronic Structure Techniques Conference (LUEST) 2016 Gustavo E. Scuseria and Peter Pulay

JULY 18-22, 2016Molecular Rotors, Motors, and Switches Ivan Aprahamian, Edith Sevick, and David Amabillino

AUGUST 07-12, 2016Advanced Particle Imaging Techniques: 1986–2016 and Beyond David W. Chandler and Paul L. Houston

SUMMER PROGRAMSJUNE 01–SEPTEMBER 30, 2016Scientists in Residence Summer Program Mark Kozak and Kristen Redd

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Nucleic Acid Chemistry Workshop JULY 25-29, 2016Led by: Scott Silverman and Sheila David

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TSRC’s budget is developed and approved annually by the Board of Directors. TSRC’s finances are managed by Shugars & Company Certified Public Accountants and Consultants, and audited by Green & Associates LLC. TSRC’s financial calendar ends annually on December 31st. The 2016 TSRC Annual Report includes financial statements for the 2015 and 2016 calendar years.

Revenues, Gains, and Other SupportLodging Revenue, 62%Registration Fees, 28%Food Revenue, 4%Contributions, 2%Investment Income, 1%Workshop Support, 1%

ExpensesProgram Expenses, 83%Supporting Services Expenses, 17%

STATEMENT OF FINANCIAL POSITION

December 31, 2016 (with comparative financials as of December 31, 2015)

ASSETS 2016 2015

Cash $282,209 $67,969

Investments 501,822 634,454

Accounts Receivable 2,646 -

Prepaid Expenses 88,995 71,629

Equipment, Net of Depreciation 2,820 7,654

Total Assets $878,492 $781,706

LIABILITIES & NET ASSETS

Accounts Payable & Accrued Liabilities $141,138 $5,943

Deferred Revenue 65,335 24,740

Long Term Debt - -

Total Liabilities 206,473 30,683

Net Assets

Temporarily Restricted 339,638 308,763

Unrestricted 332,381 442,260

Total Net Assets 672,019 751,023

Total Liabilities & Assets $878,492 $781,706

STATEMENT OF ACTIVITIES

December 31, 2015 (with comparative financials as of December 31, 2015)

REVENUES, GAINS AND OTHER SUPPORT UnrestrictedTemporarily

Restricted 2016 2015

Registration Fees $393,579 - $393,579 $412,026

Workshop Support 10,445 10,445 22,500

Lodging Revenue 857,661 857,661 904,738

Food Revenue 50,681 50,681 35,707

Contributions 8,849 15,000 23,849 24,950

Investment Income 7,986 7,976 15,962 21,575

Unrealized Gain/(Loss) on Investments 18,717 13,963 32,680 (43,790)

Other Revenue 7,996 7,996 925

In Kind Contributions - - - -

Net Assets Released from Restriction 6,064 (6,064) - -

Total Revenue, Gains, and Other Support $1,361,978 30,875 1,392,853 1,378,631

EXPENSES

Program Expenses $1,227,696 - $1,227,696 $1,173,152

Supporting Services Expenses 244,161 - 244,161 269,517

Total Expenses 1,471,857 - 1,471,857 1,442,669

Change in Net Assets (109,879) 30,875 (79,004) (64,038)

Net Assets, Beginning of Year 442,260 308,763 751,023 815,061

Net Assets, End of Year $332,381 $339,638 $672,019 $751,023

TSRC Participants in 2016By Geographic Location 1-32 33-64 65>

Total Participants: 1,266By Gender 22% Female78% Male

To realize TSRC’s full potential, the organization seeks to expand its programming and funding sources. Please consider supporting one of the following funds.

A hallmark of the summer in Telluride is the weekly TSRC Town Talks—public lectures given by world renowned scientists. TSRC fuels the intellectual curiosity of the local community while providing the opportunity for direct engagement with TSRC scientists.

TOWN TALKS SUMMER 2016 “Looking for Life in All the Right Places” Michael H. New, NASA “Science and the 2016 Presidential Election” Franz Geiger, Northwestern University“Clouds in a Bowl of Soup” Graham Feingold, NOAA Earth System Research Laboratory “Science & Healthcare: This Time It’s Personal!” Paul O’Shea, The University of British Columbia“Drug Recalls, Patent Fights, and Chocolate: Adventures in Crystal Packing” Greg Beran, University of California “Zen and the Art (Science) of Celestial Navigation: Navigating the Oceans and the Molecular World” Eric Bittner, University of Houston“The Salty Sea Within Us” Thomas Kleyman, University of Pittsburgh“Beyond Watson & Crick: DNA Quadruplexes and Their Roles in Aging, Cancer, and Zika Virus” Cynthia Burrows, University of Utah

TSRC is tax-exempt nonprofit corporation.

TSRC Facility Capital Campaign Funding a dedicated year-round TSRC facility in the Telluride region to not only accelerate new ideas and future collaborations but expand the frontiers of science and technology.

Telluride School on Theoretical Chemistry (TSTC) Endowment Fund Providing tuition, lodging, and travel support for students attending TSRC’s original graduate-level summer school.

TSRC General Education FundFunding educational outreach—including TSRC graduate-level summer schools, TSRC Town Talks, professional development for STEM teachers, and collaborations between TSRC scientists and the Pinhead Institute.

Future of TSRC Fellowship Funds Supporting outstanding graduate students and postdoctoral fellows through the Paul Barbara Fellowship and the Peter Salamon Award.

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BOARD OF DIRECTORSOFFICERSJohn Straub

TSRC President and Chair of the Board of Directors Boston University

Eran Rabani TSRC Treasurer UC Berkeley and Tel Aviv University

Michael FeigTSRC Secretary Michigan State University

MEMBERSMillard Alexander

Ex-Officio, Immediate Past President University of Maryland

Miles Cook Director of Atlanta Office and Partner of Bain & Company, Inc

Patrick DwyerManaging Director, Merrill Lynch

Ron EstlerFort Lewis College

Bern KohlerOhio State University

Audrey Marnoy Marketing Strategist and Philanthropist

David ReichmanColumbia University

Jack SimonsEx-Officio, Immediate Past Treasurer, University of Utah

Joan-Emma SheaUniversity of California, Santa Barbara

STAFFMark Kozak, Executive Director mark@telluridescience.org 970 708 4426

Kristen Redd, Managing Director kristen@telluridescience.org 970 729 8375

Chris Rauchnot, Operations ManagerClaire Ricks, Science Writer

PROGRAM STAFFMichael FortenberrySarah FriedbergGrace HennessyTJ FultonWarren FultonMishak GombergAlexa Posner Peters Kody Shugars Kole Shugars

TSRC INTERN Lehl Chase-Nason

LOOKING FORWARDWith the new clarity that TSRC gained through its strategic planning effort, the organization is excited to continue its role as the world’s leading independent molecular science center, advancing new ideas and building collaborations across 600 international and domestic institutions.

POST OFFICE BOX 2429 TELLURIDE, COLORADO 81435 USA

@TellurideSci

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ANNUAL REPORT 2016

EXPANDING THE FRONTIERS OF SCIENCE

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