Anatomy & Physiology Lecture Notes - Ch. 3 cells - part 3

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Which organelle is responsible for: 1.Degrading worn-out organelles 2.Synthesis of lipids and steroid molecules 3.Packaging proteins for export, modifying proteins for membranes, packing enzymes into lysosomes 4.Modifying proteins 5.Containing enzymes that convert toxic substances to hydrogen peroxide, then water 6.Making proteins 7.Cellular respiration 8.Movement of cell parts, cell motility,

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Transcript of Anatomy & Physiology Lecture Notes - Ch. 3 cells - part 3

Page 1: Anatomy & Physiology Lecture Notes - Ch. 3 cells - part 3

Which organelle is responsible for:1. Degrading worn-out organelles2. Synthesis of lipids and steroid molecules3. Packaging proteins for export, modifying

proteins for membranes, packing enzymes into lysosomes

4. Modifying proteins5. Containing enzymes that convert toxic

substances to hydrogen peroxide, then water6. Making proteins7. Cellular respiration8. Movement of cell parts, cell motility,

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Part 3: Cytoplasm & Nucleus

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Between plasma membrane & nucleus Three elements:

CytosolCytosol: fluid Eg. water, proteins, salts, sugars

OrganellesOrganelles: specific functions InclusionsInclusions: chemical substances that

vary depending on cell type Eg. glycogen (liver), lipid droplets (fat

cells), melanin (skin & hair)

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“little organs” Specialized compartments specific

functions Membranous = membrane-bound

Mitochondria, peroxisomes, lysosomes, ER, Golgi apparatus

Nonmembranous = no membranecytoskeleton, centrioles, ribosomes

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System of organelles that work to1. Produce, store, export biological

molecules2. Degrade harmful substances

Nuclear envelope, rough ER, smooth ER, Golgi apparatus, secretory vesicles, lysosomes

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Control center contains DNA Most cells have only 1 nucleus

Multinucleate: many nuclei (muscle, some liver cells)

Anucleate: no nucleus (mature RBC) Three main structures:

1.Nuclear envelope2.Nucleoli3.Chromatin

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Multinucleated Muscle Cells

Multinucleated Liver Cells

Anucleated Red Blood Cells

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Double membrane barrier surrounds nucleusOuter part continuous with Rough ER

Nuclear pores: control entry/exit of molecules

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Dark-staining bodies in nucleus 1-2 per cell Site where ribosomes are made

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ChromatinChromatin = DNA + Proteins Nucleosome = DNA wrapped around 8 histone proteins Histones allow for compact and orderly packing of

long DNA molecules

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During cell division, chromatin condenses to form chromosomes.

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Make identical copies of DNA before a cell divides

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Part of cell division Replicated DNA divided into 2 daughter cells Usually lasts about an hour Interphase prophase metaphase

anaphase telophase & cytokinesis

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Gene: segment of DNA that codes for 1 polypeptide

Exon: part of DNA that codes for polypeptides

Intron: part of DNA that is noncoding (not “junk”!)

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Transcription: RNA formed from DNAOccurs in nucleusTypes: mRNA, tRNA, rRNA

Translation: protein synthesispolypeptide formed from mRNAOccurs in cytoplasmBy ribosomes

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Any substances outside cells1. Body fluids (blood plasma, interstitial fluid)2. Cellular secretions (saliva, mucus, gastric

fluids)3. Extracellular matrix (ECM): “glue” that

holds cells together; jelly-like substance made of proteins (like collagen) and carbs