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Accuracy Ensured. Performance Ensured. Confidence Ensured.

iba-dosimetry.com

MONTE CARLO QAPatient Plan QA and Dose Check with SciMoCaTM

What if your patient QA provides...... the accuracy of Monte Carlo?

... time savings and automation?

... confidence in your entire planning process?

SciMoCaTM delivers.

Find out how!

Robust Monte Carlo QA with SciMoCaTM fulfills your needs

Accuracy Ensured. Monte Carlo QA dose calculation accuracy SciMoCaTM establishes a new standard for accuracy in independent patient plan QA and secondary dose check software.1 SciMoCaTM is powered by the superior accuracy of Monte Carlo dose calculation.

Performance Ensured.Workflow efficiency and automated 3D dose calculations in < 2 minutes2

SciMoCaTM identifies TPS dose errors and discrepancies with limited direct user interaction. It provides instantaneous feedback regarding treatment plan quality and achievement of planning objectives.

Confidence Ensured.Independent QA of the whole treatment planning process

With SciMoCaTM’s best-in-class Monte Carlo dose calculation algorithm and independent validation of the entire treatment planning process, you gain confidence and trust in your QA and your patient’s safety.

1 Fotina et al. Clinical Comparison of Dose Calculation Using the Enhanced Collapsed Cone Algorithm vs. a New Monte Carlo Algorithm. Strahlenther Onkol 187, 433–441. 2 Typical calculation times of SciMoCaTM Monte Carlo: 1-2 minutes using recommended hardware.

Accuracy Ensured.

Accuray InCise2™ CyberKnife® dose distribution

by SciMoCaTM

SciMoCaTM compared against Accuray Precision 1.0

(Monte Carlo), gamma analysis 2%/1 mm

■ The SciMoCaTM Monte Carlo algorithm matches the precision of top-tier solutions like Varian´s Acuros® and Accuray´s Precision® Monte Carlo.#

■ Extraordinary accuracy due to: Customized machine-specific beam models Quality of the beam modeling process Specific Monte Carlo implementation

1 SciMoCaTM achieves an accuracy of < 1 % and matches the preci sion of such top-tier algorithms as Varian´s Acuros® and Accuray´s Precision® Monte Carlo. SciMoCaTM published results: Gamma 2 % / 2 mm pass > 97 %, with deviation SciMoCaTM vs. Acuros® of mean dose in patients < 1%: Hoffmann et al., Validation of the Acuros® XB dose calculation algorithm versus Monte Carlo for clinical treatment plans. Med Phys. 2018 June 16. 2 Kry et al. (2019). Independent recalculation outperforms traditional measurement-based IMRT QA methods in detecting unacceptable plans. Medical Physics. 46. 10.1002/mp.13638. 3 M.T.W. Milder et al. Validation and clinical use of a Monte Carlo algorithm for Cyberknife patient-specific QA. ESTRO 2019 EP-1767. Conclusion: “A commercially available 3D dose re-calculation for individual Cyberknife MLC plan QA has been successfully implemented in the clinic, replacing time-consuming SRS1000 measurements, with fewer false alarms and similar sensitivity.”

■ SciMoCaTM Monte Carlo is extremely accurate, especially in complex geometries with inhomogeneities and outside of commissioning conditions.

■ Linac beam models are generated specifically for each customer using proprietary processes and dedicated expert tools, backed by extensive expertise.

Why accuracy matters Fully trust the results of your secondary

dose calculation.

Exceptional QA sensitivity and specificity to define meaningful action levels.

Find actual errors and not deviations caused by sub-standard dose calculations.2

Avoid investigating false failing cases due to non-accurate patient QA methods.3

< 1 % Accuracy of Monte Carlo QA dose calculation1

Tight Gamma - High Pass Rates ■ Excellent agreement of Monte Carlo dose with TPS dose even

for tight gamma criteria

Variety of settings for comprehensive gamma analysis Gamma distribution map

Monte Carlo Calculation Speed“SciMoCaTM offers an impressive calculation speed – a full 3D dose calculated by a Monte Carlo dose engine within minutes! In addition, the plan QA process is automated. Once we sent the final DICOM plan from the TPS, SciMoCaTM automatically performs the Monte Carlo calculation and analysis of our plans, which is very valuable in a busy RT department.“

Nadir Kucuk, MSc, Head of Medical Physics, Anadolu Medical Center, Turkey. Center of Excellence for Accuray and in affiliation with Johns Hopkins Medicine, USA

Dose difference plot in % (AcurosTM – SciMoCaTM Monte Carlo) for a cervix patient showing no deviations exceeding 1 % in the treatment area.

SciMoCaTM Accuracy PublishedValidation of the Acuros XB dose calculation algorithm versus Monte Carlo for clinical treatment plan. Lone Hoffmann, Markus Alber, Matthias Söhn, Ulrik Vindelev Elstrøm

Med. Phys. 45 (8), August 2018

Volume 45, Number 8

The International Journal of Medical Physics Research and Practice

August 2018

Published for the American Association of Physicists in Medicine (AAPM) by Wiley. Medical Physics is an offi cial journal of the AAPM, the International Organization for Medical Physics (IOMP), and the Canadian Organization of Medical Physicists (COMP).

Medical Physics is a hybrid gold open-access journal.

Discover this journal online at

wileyonlinelibrary.com/journal/mp

Illustration of a graphical user interface (GUI) for preprocessing images, computing radiomic feature maps, and comparing

computed feature maps with those derived from other software. Panel (a) illustrates the GUI for selecting an image fi lter, e.g., a three-

dimensional wavelets fi lter, and its associated parameters. Panel (b) illustrates visualization of radiomic feature maps, pre-processed

images, and the original image. This particular example shows a computed tomography image and the HLH direction Coifl et wavelets

pre-processed image.

[From Figure 3 in “Technical Note: Extension of CERR for computational radiomics: a comprehensive MATLAB platform for

reproducible radiomics research” by Apte et al., Med Phys. 45, 3712–3719 (2018).]

mp_v45_i8_cover.indd 1mp_v45_i8_cover.indd 1 8/1/2018 9:07:17 AM8/1/2018 9:07:17 AM

Click/scan to read the open access publication

Performance Ensured.

Click/scan to watch the workflow video (4 min)

Automated 3D Monte Carlo dose calculations in < 2 minutes1

■ The speed of the SciMoCaTM Monte Carlo engine for full 3D dose calculation is truly impressive.

■ The algorithm makes optimum use of modern processing hardware architecture.

■ Outstanding performance is enabled through the fast dose engine, automated workflow, and background calculations.

Workflow efficiency ■ Simply send your plans from the TPS - Check the results

whenever you have time.

■ Get almost instant results - in case you need them right away.

■ SciMoCaTM provides the full and immediate overview whether the treatment plan is within constraints or not.

■ Reduce your patient QA time so you can concentrate on other relevant tasks.

■ Use linac time efficiently by minimizing patient QA measurements with sensitive and accurate Monte Carlo QA.

1 Typical calculation times of SciMoCaTM Monte Carlo: 1-2 minutes using recommended hardware. 2 Calculation times on dual 8-core Intel Xeon E5-2690 server with hyperthreading (32 logical cores) for dose calculation with final statistical uncertainty of 1%.

prostate, static IMRT(8 beams, 44 segments)

prostate/LN, dMLC(7 beams, 140 control points)

head & neck, VMAT(2 arcs, 293 control points)

PTV volume 193.3 cc 979.8 cc 834.4 cc

voxel size 3 mm 3 mm 3 mm 2 mm

calculation time 15.8 sec 55.6 sec 40.9 sec 118.9 sec

Monte Carlo Calculation Speed and Accuracy2

Automatic process & calculationTreatment plans are simply exported via DICOM from your TPS to the SciMoCaTM dose calculation server. SciMoCaTM then starts the Monte Carlo calculation automatically.

The patient worklist is automatically updated to keep the user informed about the current QA status of each patient plan.

Automated status emails will alert you and allow you to review your QA results anytime and anywhere in your hospital network.

Automatic analysisSciMoCaTM provides automated plan quality and dose difference evaluation based on customizable protocols for both PTVs and OARs. This allows users to evaluate plan quality as well as identify dose discrepancies based on user-defined, dose-difference thresholds.

An intuitive, color-coded pass/fail display ensures verification efficiency.

Additional step: 3D image visualization & comparative DVHDVHs for the treatment plan as well as the independent SciMoCaTM dose are compared. The DVH viewer enables a detailed evaluation of individual OARs and targets.

To evaluate dose discrepancies on the patient anatomy level, SciMoCaTM includes a slice viewer to visualize the TPS dose, SciMoCaTM recalculated Monte Carlo dose, and gamma index distribution map.

The patient worklist provides instant overview of each patient QA

Automatic analysis and display of dose verification results

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2

1

MU check / Plan complexity scoresComparison of TPS MU vs. Monte Carlo-calculated MU.

Access the plan complexity and the need for additional patient QA.

DVH & dose difference of TPS vs. independent Monte Carlo dose

4

AUTOMATED WORKFLOW — APPLICATION SIMPLICITY

Beam 1 2

Beam Name 1A01 1A02

Min Gantry 180.00° 50.00°

Max Gantry 300.00° 180.00°

Gantry Arc 240.00° 260.00°

TPS MU 192.21 259.21

SMC MU 192.96 259.21

TPS Beam Dose (Gy) 0.95 1.02

SMC Beam Dose (Gy) 0.94 1.02

Beam Dose Difference 0.39% 0.39%

Field Irregularity 2.85 2.77

Small Field Contribution 1.19 1.42

Off Axis Contribution 1155.53 896.23

Leaf Travel Variability 0.04 0.02

Leaf Gantry Synchronization 0.06 0.04

Max Leaf Travel Per MU 20.70 29.18

Max Gantry Rotation Per MU 5.01 5.96

TPS MU 192.21 259.21

SMC MU 192.96 259.21

Confidence Ensured.

QA of the whole treatment planning processSciMoCaTM provides a full end-to-end test of your treatment planning process without additional effort.

■ Find all relevant errors from imaging to plan export.

■ Overcome gaps seen in other patient QA methods and gain higher QA safety and efficiency as well as peace of mind for the entire treatment team.1

■ Reliably find real errors based on SciMoCaTM’s proven specificity and sensitivity to detect the clinically relevant issues.1

■ Gain full confidence beyond the traditional QA of your TPS algorithm.

Confidence in your QA results ■ Gain trust in the accuracy of your QA dose calculations.

■ Clearly attribute the source of an error to planning process or to delivery.

■ Be sure about your patient’s safety and gain peace of mind.

QA of the Treatment Planning Process

Imaging and image segmentation

Planning objectives

Plan segmentation

TPS dose calculation

Plan acceptance

Plan export

1 M.T.W. Milder et al. Validation and clinical use of a commercial Monte Carlo algorithm for Cyberknife patient-specific QA. ESTRO 2019 EP-1767.

Patient QA at your fingertipsStay up to date and aware of your patient QA. Automated status emails will alert you and allow you to review your QA results anytime and anywhere in your hospital network.

Independent Patient QASciMoCaTM Monte Carlo ensures fully independent quality assurance from your TPS and treatment machines, a fundamental requirement for user confidence in the accuracy and validity of the QA outcome.

SciMoCaTM around the world

SciMoCaTM is the proven and widely used Monte Carlo-based patient plan QA solution. Healthcare centers around the world trust SciMoCaTM for quality assurance in Radiation Therapy.

Monte Carlo Accuracy with High Pass Rates“SciMoCaTM’s Monte Carlo accuracy allows us to use very tight plan evaluation criteria of 2 % / 1 mm gamma. Nonetheless, we still see consistently high pass rates of > 95 %. Based on our clinical experience with more than 150 patient plans, SciMoCaTM offers the specificity and sensitivity to capture the real errors.”

Christoph Fuerweger Ph.D., Head of Medical Physics, European Cyberknife Center, Munich, Germany

Click/scan and watch the SciMoCaTM CyberKnife® webinar

Monte Carlo. Unlimited.

Support for all major RT treatment machines#

■ All C-gantry-based conventional Linacs from Elekta™, Siemens, and Varian.

■ Varian Halcyon™ / Ethos™.

■ CyberKnife® (cones, Iris, and MLC).

■ TomoTherapy® / Radixact®. 

TPS Support ■ SciMoCaTM supports all treatment planning systems that

provide DICOM export, as well as the CyberKnife® TPS.

Application Support ■ SciMoCaTM supports a wide range of treatment

techniques such as 3D, IMRT, VMAT, SBRT/SRS, TomoTherapy®, and CyberKnife® treatments.

Complementary Solution: Add QA Measurements to your Monte Carlo Dose CalculationComplement your efficient Monte Carlo dose calculation workflow with selective mea-surements as needed and when required.

■ The IBA Dosimetry Head & Neck Phantom offers full flexibility for ionization chamber and film measurements.

■ Clearly identify the source of errors outside of the treatment planning process and data flow.

■ Ideal for CyberKnife®: The combination of Monte Carlo dose calculation and QA measurements perfectly address the specific high-resolution QA needs.

CUSTOMIZED BEAM MODELS

Monte Carlo. Made Easy.

Effortless installation, seamless clinical integration

■ SciMoCaTM only requires a small set of data.1

■ Custom beam models created for your treatment machine.

1 Data required: set of PDDs with output factors, cross and diagonal profiles, absolute dose calibration.

Click/scan to watch the webinar

Validation of your Beam Data Accuracy with Monte CarloAdded value from your SciMoCaTM custom beam modeling:

■ Monte Carlo verification of your existing beam data (audit), including validation report.

■ Ensure your base beam data is correct for the most challenging treatment plans.

Learn how SciMoCaTM Monte Carlo is used to independently validate commissioning beam data and to tune the TPS beam model for high accuracy dose planning.  

Click/scan to watch the webinar

Clinical Experience with Monte Carlo Plan QA

Watch the presentation of the implementation and clinical experience of SciMoCaTM at Heidelberg. From installation to workflow efficiency and the analysis of SciMoCaTM accuracy for Linac, TomoTherapy®, and CyberKnife® cases.#

Dr. Kai Schubert, Medical Physicist, Dept. of Radio-Oncology and RT, University Clinical Heidelberg, Germany

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Scimoca_Rev.2-0420-E | © IBA 2020 | All rights reserved | Manufacturer: Radialogica SMC_MM_003-EN. | Global Distributor: IBA Dosimetry GmbH. Technical specifications and product features are subject to change without prior notice. # All product and company names are trademarks™ or registered® trademarks of their respective holders. Use of them does not imply any relationship, sponsorship, or endorsement between IBA or its products and the owners of these trademarks.

Minimum recommended specifications: Recommended specifications:

CPUx64-based processors 4C/8T,

1.4 GHz or fasterx64-based processors 8C/16T,

1.4 GHz or faster

RAM 12 GB of RAM 20 GB of RAM

Operating System Windows™ Server 2012 R2 Standard or newer with IIS enabled#v

Supported Web-Browser Google Chrome, Internet Explorer, Mozilla Firefox, Microsoft Edge#

Software .NET 4.6.2, .NET 3.5 (Windows Server 2016+) IIS#

Database Microsoft SQL Server 2012 Express or newer# Microsoft SQL Server 2012 Standard or newer#

Monitor Medical grade with minimum native display resolution of 1024 × 768 and 32-bit color

Language English (US or UK)

Free Hard Disk Space 20 GB

SciMoCaTM Recommended System Requirements (v. 1.5 +)

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