Abnormalities of the Testes and Scrotum

download Abnormalities of the Testes and Scrotum

of 34

Transcript of Abnormalities of the Testes and Scrotum

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    1/34

    Abnormalities Of The Testis And Scrotum

    Ahmed Al-Sayyad

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    2/34

    Embryology

    Testicular differentiation is initiated in the 7th

    week of gestation by the SRY gene

    At 4 to weeks! gestation" the genital ridgesorgani#e$ This is followed by migration of

     %rimordial germ cells

    At 7 to & weeks! both sertoli and leydig cells ha'e

    de'elo%ed

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    3/34

    Embryology

    (uring the &th week" the fetal testis begins to secretetestosterone and )*S inde%endent of %ituitary hormonalregulation

    )*S is secreted by the Sertoli cells and causesdegeneration of the m+llerian structures after the &th weekof gestation

    The gubernaculum a%%ears at the 7th week of embryologic

    de'elo%ment where its cranial as%ect en'elo%s the caudae%ididymis and lower %ole of the testis and e,tendscaudally into the inguinal canal" where it maintains a firmattachment

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    4/34

    ry%torchidism

    ./ of full-term male newborns and .0$./ incidence in

     %remature infants

    )ore %re'alent among %reterm" small-for-gestational-age"

    low-birth-weight" and twin neonates

    A%%ro,imately 70/ to 77/ of cry%torchid testes will

    s%ontaneously descend by . months of age

    1y 2 year of age" the incidence of cry%torchidism declinesto about 2/ and remains constant throughout adulthood

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    5/34

    (escent 3actors

    ormonal5 androgens")*S"estrogen"descendin

    6ubernaculum

    63 and 6R8

    E%ididymis

    *ntra-abdominal %ressure

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    6/34

    Terminology

    9ndescended

    Ascended

    6liding

    Retractile

    Ecto%ic

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    7/34

     on%al%able testis

    *ntra-abdominal

    :anishing

    Atro%hic

    )issed on e,amination

    1ilateral non%al%able work-u%

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    8/34

    onse;uences of ry%torchidism

    *nfertility

     eo%lasia

    ernia

    Torsion

    Trauma

    osmetic

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    9/34

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    10/34

    *n'estigations

    ormones

    9S

    T

    )R*

    =a%arosco%y

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    11/34

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    12/34

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    13/34

    ormonal Thera%y

    6 or 6nR can be used

    The lower the %retreatment %osition the better the

    results Self limiting side effects

    O'erall success rate > ?0/

    =imited indications if any

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    14/34

    Surgical *nter'ention

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    15/34

    ydrocele

     ormally" the %rocessus 'aginalis is obliterated

    from the internal inguinal ring to the u%%er

    scrotum" lea'ing a small %otential s%ace in thescrotum that %artially surrounds the testis

    Embryologic misad'entures may occur and results

    in @hydrocele" hydrocele of the cord" and

    communicating hydrocele$

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    16/34

    Sim%le ydrocele

    Sim%le @scrotal hydrocele is an accumulation of fluid

    within the tunica 'aginalis

    Results from %ersistence of or delayed closure of the

     %rocessus 'aginalis

    ommonly seen at birth" fre;uently bilateral" may be ;uite

    large$ They transilluminate and may seem ;uite tense but

    not %ainful

    )ost resol'e during the first ? years of life

    *f surgical re%air is elected" an inguinal a%%roach should be

    used

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    17/34

    ommunicating ydrocele

    8ersistence of the %rocessus 'aginalis whichallows %eritoneal fluid to communicate with thescrotum

    The classic descri%tion is that of a hydrocele thatchanges in si#e

    *t can be com%ressible during e,amination

    All should be fi,ed using an inguinal a%%roach (o it bilateral if %atient got :8 shunt or on

     %eritoneal dialysis

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    18/34

    ydrocele of the cord

    Segmental closure of the %rocessus" which lea'es

    a loculated hydrocele of the cord

    8resents as a %ainless groin mass which is mobileand transilluminates

    *nguinal e,%loration and high ligation is curati'e

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    19/34

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    20/34

    Acute Scrotum

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    21/34

    (ifferential (iagnosis

    Torsion testis

    Torsion a%%endi, testis

    Torsion a%%endi, e%ididymis E%ididymo-orchitis

    ernia

    Trauma :asculitis

    (ermatological

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    22/34

    Testicular Torsion

    True surgical emergency of the highest order

    *rre'ersible ischemic inBury may begin as soon as

    4 hours after occlusion of the cord  *ntra'aginal torsion" result from lack of normal

    fi,ation of the testis and e%ididymis to the fascialand muscular co'erings that surround the cord

    This creates an abnormally mobile testis thathangs freely within the tunical s%ace @a Cbell-cla%%er deformityC

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    23/34

    Testicular Torsion

    a%%ens in any age but most commonly in

     %re%ubertal males

    8resentation5 8ain"D:"8oor a%%etite"%re'iouse%isodes

    E,amination5Swelling"Tenderness"igh

    riding"trans'erse orientation"=oss of cremasteric

    refle,

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    24/34

    Testicular Torsion

    (o%%ler 9S may hel% in the diagnosis

    )anual detorsion may be attem%ted in ER 

    Scrotal e,%loration is mandatory (etorte the affected testis and %e, the other side

    while waiting for the testis to %ink u%

    *f the testis is still ali'e %e, it " if not do anorchiectomy

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    25/34

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    26/34

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    27/34

    *ntermittent Torsion

    Recurrent e%isodes of acute" self-limited scrotal

     %ain

     ormal %hysical e,amination will be found in- between

    *f the sus%icion is strong " electi'e scrotal

    e,%loration and bilateral orchio%e,y should be

     %erformed

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    28/34

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    29/34

    Torsion A%%endi, Testis

     %resentation is e,tremely 'ariable" from an

    insidious onset of scrotal discomfort to an acute

     %resentation identical to torsion testis E,am5Tenderness or mass in the u%%er %ole"1lue

    dot sign"cremasteric refle, usually %resent

    (o%%ler 9S may hel% in diagnosis

    )anagement5conser'ati'e"%ain meds"limit acti'ity

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    30/34

    E%ididymitis

    Rare in %ediatrics

    8resentation5%ain"swelling"erethyma"=9TS"fe'er"

    urethral discharge"ST(s *n'estigations5%yuria" bacteriuria" %ositi'e urine

    culture" increased flow on do%%ler

    *: Ab, gi'en if systematically ill then oral for

    total of 20-24 days Screening 9S usually indicated

    :96

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    31/34

    :aricocele

    (ilated and tortuous 'eins of the %am%iniform

     %le,us

     3ound in a%%ro,imately 2F/ of male adolescents"with a marked left-sided %redominance

    Etiology5increased 'enous %ressure in the left

    renal 'ein" incom%etent 'al'es of the internal

    s%ermatic 'ein

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    32/34

    'aricocele

    9nilateral 'aricocele may affect testicular function

     bilaterally

    To,ic effect of 'aricocele may manifest as testicular

    growth failure" semen abnormalities" =eydig cell

    dysfunction" and histologic changes

    8ossible mechanisms5reflu, of adrenal metabolites"

    hy%erthermia" hy%o,ia" local testicular hormonal

    imbalance" and intratesticular hy%er%erfusion inBury

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    33/34

    'aricocele

    8resentation5asym%tomatic"%ain"scrotal

    mass"infertility"atro%hy

    6rading on %hysical e,amination Obtain scrotal 9S

    Treat if there is loss of 'olume @G ? mls or G ?0/

  • 8/17/2019 Abnormalities of the Testes and Scrotum

    34/34

    Treatment Alternati'es

    *nguinal =igation and Subinguinal =igation

    Retro%eritoneal and =a%arosco%ic =igation

    Trans'enous Occlusion om%lications5hydrocele"recurrence"testicular

    atro%hy