BIOL226Lec11 Scrotum,Prostate

download BIOL226Lec11 Scrotum,Prostate

of 30

Transcript of BIOL226Lec11 Scrotum,Prostate

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    1/30

    PROSTATE GLAND

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    2/30

    I. Introduction/General Information

    A. Attached inferiorly to urinary bladder by

    ligaments

    B. Posterior to pubic symphysis

    C. Surrounds superior portion of urethraD. Anterior to rectum (palpation, ultrasound)

    E. Conical shape

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    3/30

    Introduction, Prostate Gland, continued

    F. Walnut sized

    1. 4 cm trans x 2 cm A/P x 3 cm Sup/Inf

    G. Lightly encapsulated

    1. Fibrous connective tissue

    2. Smooth muscle3. Capsule extends into lobes

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    4/30

    II. Prostate Gland: Detailed Anatomy

    A. Largest male

    accessory

    gland

    B. Located in

    subperitoneal

    compartment(between pelvicdiaphragm &

    peritoneum)Prostate Gland, Mid-sagittal Section

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    5/30

    Prostate Gland: Detailed Anatomy

    C. Enclosed in fascial sheath

    (aka: prostatic sheath)

    1. Inferiorly, sheath is continuous

    with superior fascia of

    urogenital diaphragm

    2. Posteriorly, sheath forms part of

    retrovesical septum

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    6/30

    Prostate Gland: Detailed Anatomy

    D. Double Capsule

    1. Fibrous portion contacts gland2. External capsule formed by pelvic

    fascia

    3. Venous plexus lies between

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    7/30

    Male Reproductive System, Posterior View

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    8/30

    Detailed Anatomy, contined

    E. Conical shape with base (sup), apex (inf),

    four surfaces

    1. Surfaces: posterior, anterior, right &left inferolateral

    2. Base (aka: vesicular surface): superior

    a. Attached to neck of urinary bladder

    b. Prostatic urethra enters middle of

    base close to anterior surface

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    9/30

    Prostate Anatomy

    Prostatic Urethra

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    10/30

    Detailed Anatomy, contined

    3. Apex: inferiora. Rests on superior fascia of urogenital

    diaphragm muscle

    b. Associated with sphincter urethraec. Contacts medial margins oflevator ani

    muscles

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    11/30

    Detailed Anatomy, contined

    4. Posterior surface: triangular, flat

    5. Anterior surface: narrow, convex

    6. Inferiorolateral surfaces

    a. Meet with anterior surface

    b. Rest on levator ani fascia above

    urogenital diaphragm

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    12/30

    Detailed Anatomy, contined

    F. Lobes of the Prostate

    1. Divisions are arbitrary, indistinct

    2. Usually divided into

    a. two lateral lobesb. one median lobe

    c. anterior and posterior lobes

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    13/30

    Lobes of the Prostate, continued

    3. Median lobe

    a. Lies posterior and superior toprostatic utricle and ejaculatory

    ducts

    b. May project into urinary bladder

    c. Utricle lies within lobe1. Vestigial remains of uterine

    homolog

    2. Sometimes called uterus

    masculinis

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    14/30

    Lobes of the Prostate, continued

    4. Lateral lobes

    a. Comprise the greatest mass ofthe gland

    b. Contain most secretory tissue

    c. Are continuous posteriorly

    5. Glandular tissue with varying amounts

    of fibrous tissue

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    15/30

    Lobes of the Prostate, continued

    Prostate Glandin situ

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    16/30

    Detailed Anatomy, continued

    G. Blood & lymph

    1. Arteries derived

    from:

    a. Internal pudendalartery

    b. Inferior vesicalartery

    c. Middle rectalartery

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    17/30

    Blood & Lymph, continued

    2. Veins

    a. Form venous plexusb. Drain into internal iliac veins

    c. Communicate with vesical &

    vertebral venous plexuses

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    18/30

    Blood & Lymph, continued

    3. Lymphatics

    a. Most terminate in internal iliac &sacral nodes (unable to palpate)

    b. From posterior: to external iliac

    nodes (unable to palpate)

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    19/30

    Detailed Anatomy, contined

    H. Glandular tissue

    1. 30 - 50 different glandular elements

    a. Serous glands

    b. 20 - 30 ducts empty into prostaticurethra

    2. Most are posterior & lateral to urethra

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    20/30

    Blood & Lymph, continued

    3. Prostatic secretionsa. Thin, milky, alkaline (looks like

    skim milk)

    b. Discharged at ejaculation

    c. Make up ~ 1/3 of semen

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    21/30

    Detailed Anatomy, continued

    I. Prostate size changes

    1. Small at birth2. Enlarges at puberty

    3. Maximum at about 13

    4. Progressive enlargement after 40

    5. Sometimes: undergoes atrophy

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    22/30

    III. Pathology

    A. Benign

    prostatichypertrophy

    (BPH):

    1. Affects ~90%

    of men >50

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    23/30

    BPH, continued

    2. Common cause of urethral obstruction:

    causes

    a. Nocturiab. Dysuria

    c. Urgency

    d. Back-pressure effects

    e. Complete obstruction can occur

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    24/30

    Pathology, continued

    B. Prostate cancer1. Most common

    cancer in males

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    25/30

    Pathology, continued

    2. Metastasizes via blood (hematogenous)

    or lymph (lymphogenous)3. Common sites: vertebrae, pelvis

    a. Via venous plexus surrounding

    prostateb. Bone or direct metastasis most

    common

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    26/30

    Prostate Cancer: Routes of Metastasis

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    27/30

    Pathology, continued

    C. Prostatitis (accompanied by cystitis)

    1. Inflammation of gland

    2. Gland enlarges, becomes tender

    3. Causes: gonorrhea? Other UTIs?

    STDs?

    4. May require antibiotics, massage5. Symptoms: chills, painful urination,

    back pain

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    28/30

    Pathology, continued

    A. Prostatic concretions (aka: corporaamylacea [starch bodies])

    1. Small spherical or ellipsoid bodies

    2. Number increases with age

    3. May become calcified as male ages4. May simulate carcinoma

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    29/30

    Digital Rectal Exam

  • 7/28/2019 BIOL226Lec11 Scrotum,Prostate

    30/30

    Pathology, continued

    E. Rarely, prostatic abscesses develop1. Frequently caused by gonorrhea2. May rupture through to rectum, bladder,

    perineum

    3. Other causes:a. Urethritis

    b. Epididymitis