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    IntroductIon And termInology

    De Quervains tenosynovitis or tendinitis was first

    described in 1895 by Fritz De Quervain, a Swiss surgeon.

    Prior to this, the first use of the terms tenosynovitis

    and crepitating peritendinitis to describe injuries to the

    tendons and surrounding tissues was by Velpeau in 1825.This condition is a wrist tendinitis with inflammation of

    the tendon sheaths of the abductor pollicis longus and

    extensor pollicis brevis.

    epIdemIology

    De Quervains tenosynovitis is the most common

    tenosynovitis affecting the dorsal tendons of the wrist.

    It is usually diagnosed in individuals between 30 and 50

    years of age and is ten times more prevalent among

    women than men (Dupuis, 1986). American andScandinavian studies examining the relation between

    work activities and De Quervains tenosynovitis have

    rarely distinguished between this condition and other

    type of tendinitis of the wrist and hands. Epidemiological

    studies have demonstrated that workers in the meat

    processing and manufacturing industries run a higher risk

    of developing tendinitis of the hand and wrist: perform-

    ing highly repetitive work increases the relative risk of

    developing De Quervains tenosynovitis to 3.3, while

    performing work requiring the exertion of great force

    increases it to 6.1. Among individuals performing workthat is both highly repetitive and forceful, the relative risk

    is 29 (Hagberg et al., 1995).

    AnAtomIcAl revIew

    The tendons of the forearm are relatively long, extending

    beyond the wrist to cover the dorsal aspect of the hand

    and thumb. The tendons of the abductor pollicis longus

    and extensor pollicis brevis both run through the groove

    of the radial styloid process in the first of the six dorsalcompartments of the wrist and have their insertion at

    the base of the first metacarpal and the proximal phalanx

    of the thumb (Figure 1.1).

    These muscles, individually and jointly, extend and

    abduct the trapezometacarpal joint and extend the

    metacarpophalangeal joint. They are also active during

    radial deviation and, to a lesser extent, flexion of the

    wrist (Kendall et al., 1988). Both are innervated by the

    posterior interosseous branch of the radial nerve, which

    originates mostly in the C6, C7, and C8 roots.

    pAthophysIology

    De Quervains tenosynovitis is a stenosing tenosynovitis

    involving inflammation of the tendon sheath of the

    extensor pollicis brevis and abductor pollicis longus

    (Dupuis, 1986; Hagberg et al., 1995). The rigidity of the

    structures and limited space within the wrist compartment

    favour the development of tenosynovitis.

    General Considerations1

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    Guide to the Diagnosis of Work-RelatedMuskuloskeletal Disorders

    Tenosynovitis may result from trauma or from

    excessive friction between the tendon and surroundingtissues during movements of the thumb and wrist. The

    thickness of the synovial membranes is an indication of

    the stage of the tendinitis. As the inflammation progresses,

    the tendon tends to thin out and become more friable,

    and stenosis increases. In the final stages, the sheath of

    the first dorsal compartment thickens, becomes fibrous,and impinges on the space of the fibro-osseous groove.

    This may result in trigger finger, a chronic form of De

    Quervains tenosynovitis.

    Figure 1.1

    Insertion and Action of the Tendons of the Extensor Pollicis Brevis

    and Abductor Pollicis Longus

    Extensor pollicis brevis Abductor pollicis longus

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    generAl consIderAtIons

    Tendinitis and tenosynovitis may occur when muscle and

    tendon structures are subjected to:

    regular biomechanical strain which, over the long

    term, exceeds the limits of the tendons and synovial

    membranes intense or unusual biomechanical strain (resumption

    of working activities after an absence, increase in

    production rates, modification of tasks, intense

    practice of a sport or musical ins trument)

    local trauma

    Tendinitis and tenosynovitis of the upper limb may

    also be related to:

    metabolic diseases (diabetes mellitus, hypothyroidism,

    gout, ankylosing spondylitis, various collagenoses) infection such tuberculosis or a bacterial in fection

    specific conditions such as pregnancy

    De Quervains tenosynovitis may coexist with carpal

    tunnel syndrome and trigger finger.

    Tenosynovitis affecting the dorsal tendons of the

    wrist may be of two types:

    Tenosynovitisis with effusion is of infectious or

    rheumatoid origin. In the latter case, it is indica tive

    of rheumatoid arthritis and may presage polyarthritis

    (Dupuis, 1986).

    De Quervains tenosynovitis is one of the most

    common forms of the stenosing tenosynovitises,

    inflammatory conditions whose most common cause

    is microtrauma. The palmar aspect of the flexor

    digitorum profundus tendons may be involved, and

    the condition may be congenital or secondary to

    rheumatoid arthritis (Dupuis, 1986).

    work-relAtedness of musculoskeletAlstrAIn

    Excluding accidents, the primary pathophysiological

    cause of De Quervains tenosynovitis is biomechanical

    strain on the tendons of the abductor pollicis longus and

    extensor pollicis brevis in the groove of the radial styloid

    process as a result of physical activity.

    As noted in the section on epidemiolog y,

    musculoskeletal strain associated with actions that are

    highly repetitive or forceful or both is an im portant causeof hand and wrist tendinitises, including De Quervains

    tenosynovitis (Hagberg et al., 1995). De Quervains

    tenosynovitis is also associated with grasping objects with

    the fingers spread, rotation of the wrist, and pronation-

    supination of the forearm (Kuorinka and Koskinen,

    1979; Kurppa et al., 1991; Kroemer, 1989). Wrist

    movements requiring a pinch grip and frequent hand

    movements with the wrist flexed and thumb abducted

    generate great strain on the tendons of the abductor

    pollicis longus and extensor pollicis brevis.

    Finally, factors such as the use of gloves and exposure

    to cold or vibration increase the risk of developing this

    condition. Box 2.1 illustrates the movements frequently

    associated with De Quervains tenosynovitis.

    Etiology2

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    Guide to the Diagnosis of Work-RelatedMuskuloskeletal Disorders

    Most Common Stressful Movements of the Abductor PollicisLongus and Extensor Pollicis Brevis

    Strain on the thumb:

    duringwristmovements

    whilemaintainingpressureonthepalmorthehand

    useofgloves

    exposuretocoldorvibration

    Repeatedapplicationofpressurewhileflexing Loadedabductionorextension thedistalphalanxofthethumb ofthethumb

    Wristmovementsduringnormal Loadedflexion-extension orpinchprehension ofthewrist

    Applicationofthumbpressurewiththewristdeviated

    Box 2.1

    Cofactors