Voltammetric behavior and determination of the macrolide ...
29.macrolide
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Macrolides
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Transcript of 29.macrolide
![Page 1: 29.macrolide](https://reader037.fdocuments.net/reader037/viewer/2022110314/55c81ec7bb61eb2c208b45d4/html5/thumbnails/1.jpg)
Macrolides
![Page 2: 29.macrolide](https://reader037.fdocuments.net/reader037/viewer/2022110314/55c81ec7bb61eb2c208b45d4/html5/thumbnails/2.jpg)
Examples
• Erythromycin • Roxithromycin• Clarithromycin • Azithromycin
![Page 3: 29.macrolide](https://reader037.fdocuments.net/reader037/viewer/2022110314/55c81ec7bb61eb2c208b45d4/html5/thumbnails/3.jpg)
Mechanism of action
• Inhibit bacterial protein synthesis
![Page 4: 29.macrolide](https://reader037.fdocuments.net/reader037/viewer/2022110314/55c81ec7bb61eb2c208b45d4/html5/thumbnails/4.jpg)
Uses
• Atypical pneumonia caused by mycoplasma pneumoniae
• Whooping cough• Steptococcal pharyngitis, tonsillitis• Diphtheria, tetanus
![Page 5: 29.macrolide](https://reader037.fdocuments.net/reader037/viewer/2022110314/55c81ec7bb61eb2c208b45d4/html5/thumbnails/5.jpg)
Adverse effects of erythromycin
• Epigastric pain, hearing impairment, rashes, hepatitis, jaundice