2012 bio link summit slides

BIO-LINK SUMMITBioscience Businesses/Education Models: Economic and Educational Impact

April 18-20, 2 012

WELCOME!

Panel 1: Bioscience Business/Education Models

MODERATOR: Eilene Lyons, Acting Dean MSET Division, STLCC-Florissant Valley

PANELISTS:

Adam Blaszczak, InnovaBio CRO, Salt Lake Community CollegeVivian Ngan-Winward, STUDENTfacturED, Salt Lake Community College R. Kevin Pegg, Florida State College at Jacksonville Wendie Johnston, Pasadena City CollegeSuzanne Winters, BioInnovations Gateway, St. Lake City

Eilene LyonsSt. Louis Community College-Florissant Valley

BIO-LINK SUMMIT April 18-20, 2012

STLCC BioBench CRO

Community College/ Incubator Model

Eilene LyonsInterim Dean, STEM Division STLCC-Florissant Valley

STLCC Biotechnology ProgramFounding Coordinator

Pathway for Success

• Founded Fall 1999; R&D based• 2+2+2 Pathway• Bridge to STEM and Life Science CS• AAS Biotechnology• Post-baccalaureate certificate

Vision for Growth: Step 1Battelle study, January 2005“As the region’s start-up companies expand, there is likely to be

greater demand for technicians than can be produced currently. An option that might be considered to enable STLCC to expand their biotechnology offerings would be to provide lab space for the college in the new multi-tenant building being planned…”

Vision for Growth: Step 2• NSF funded CRO within BRDG Park• Primary Goal: Internships in research• Secondary Goal: Build the industry and jobs

– Lab space– High end equipment and instrumentation– Lab assistants

Growth Realized• Successful placement out of CRO

– 6 Monsanto/ Divergence– 2 Phycal– 1 Electrochaea– 1 Danforth Plant Science Center– 10 interns currently

– 1 engineering student– 1 horticulture student

http://www.divergence.com/index.php

BIO-LINK SUMMIT April 18-20, 2012

Adam BlaszczakInnovaBio, Salt Lake Community College

A new concept to partner with businesses to provide service to one partner And educational credit to another within the structure of the educational institution.

Lessons learned:It works.Fine print (word of caution) don’t try it at home. Well, try… but in our opinion…Not as easy at it sounds

Mission• Our mission is to mentor the next generation of

Biotechnology Graduates and simultaneously assist local scientific and biotech enterprises in developing research projects.

• Recipe for success – key ingredient? True balance

Stu

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Bus

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• Business side– Blanket contract reviewed by legal departments (long process) covers

for 2-5 yrs.– Scientific design for each project (short process) with proposed budget– Clearly stated deliverable (including negative data)– Set deadline for completion (give yourself extra time)– Projects with the greatest corporate attention will likely not be

contracted to Innovabio – Backburner projects yes.– Moderate priority projects with moderate to low investment– Build a reputation.– Establish trust – honesty about limitations.

The Model Real Science, Real Lab, Real Scientists.

Disadvantages of InnovaBio• Confidentiality

– Cannot enforce confidentiality agreement (under 18)

• Innovabio’s limited area of expertise– Cannot be specialists in all areas– Availability of equipment for specialized protocols

• Not a quick process– If you want it done now Innovabio is not for you

• Company needs to be involved in Innovabio for the process to work

Advantages of InnovaBio• Company owns the intellectual property• Accomplish a moderate priority project without sacrificing existing personnel

allocations– Company has only enough time for high priority projects– Moderate priority projects are still important to bottom line

• Costs are equal to or less than performing the experiment in house– Cheaper than hiring consultants

• Use of equipment and facilities for project completion– Innovabio uses their own equipment and lab space

• Minimal corporate oversight– Company provides goals and objectives– Innovabio provides updates and all developed product information and/or

materials– No need to provide direct supervision

• Availability of qualified labour pool

• Student side• Each student 30 minute interview – assessment of the skills (course 1010 and 1015 or

equivalent) and time commitment (at least 12 – 15 hours a week)• Real Challenge: Realized that as our projects are real science things are unknown and hard

to control so we are unable to tell whether the project is hard and needs some troubleshooting or the students is messing up. Real Solution: Training Packet – Great Tool for us. A set of experiments designed to give certain results when done right, plus some other lab training. This allows us to asses whether a student is truly ready to be assigned to a real project. We reserve the right to let students know during this period that they need to take more classes. Very often during this time students themselves decide that this is way over their heads and decide to take more classes and then return. Current Innovation: Short training movies embedded into Training Packet. Interactive Training Packet as an APP on iPads.

• Students assigned to real projects contracted by companies to InnovaBio.• Project Leaders – Leadership Academy. Real Challenge: how to ensure skill consistency on

projects. Real Solution: Select group of students after completion stick around – we offer them opportunities for growth – they lead and help train students for specific projects. Current Innovation: “Training Packet on Steroids”

The Model Real Science, Real Lab, Real Scientists.

Adam BlaszczakDirector, InnovaBio>20 years research experience

Mary NelsonAssistant Director, InnovaBio> 10 years research experience

Alejandro PabonResearch Associate, InnovaBio> 7 years of research experience

Director – Team leader. Scientific design, oversight and management of all the projects. Business relations and negotiations with clients. Marketing, billing and accounting. Public Relations. Assistant Director – day-to-day student oversight, evaluations and supervision. Daily project coordination and scientific resource. Recruitment.Research Associate – Project troubleshooting. Scientific resource. Report writing.

People used to believe in “natural” talents

• Step1. Separate “talented” from the “untalented”

• Step2.Provide the “talented” with a superior experience

• What really matters:– Who gets the best teaching

and most attention– Who gets the most coaching

and practice– Who gets all the

extraordinary opportunities

InnovaBio in a business of “Talent creation, not discovery”

Genius? Or just Smart…enough

Vivian Ngan-WinwardSTUDENTfracturED, Salt Lake City Community College

Vivian Ngan-WinwardDirector, Biomanufacturing Program

Biotechnology Department

This material is based upon work supported by the National Science Foundation under Grant No. 1003292.

What’s unique ?

• Contract manufacturing organization

• A complete business enterprise: Biotechnology / biomanufacturing Accounting Business Management Marketing

• A regulated yet learning-centered environment

Comprehensive entrepreneurial experience

Sustainability Potential

• Products: instructional supplies Biotechnology, & Biology, Chemistry, Health

Sci ? Custom Equipment ?

• Customers: educators SLCC & local high schools ???

• Income $$$: reinvest into CMO for Mentor / staff support New product development

Outcomes

• Forced application of knowledge and skills

• Mistakes → lessons learned• Integrated and deep learning –

Bloom’s Analyzing/Evaluating/Creating levels

• On-the-job training, before the job• Transformative mentoring• Interns want additional training

Student Testimonials“ . . .I have learned again the importance

of communication, mutual support . . .”

“. . . This experience has made me more excited and confident to work for a company . . .”

“. . .The best part about STUDENTfacturED is that I got real world knowledge and I did not have to spend hundreds of dollars on a new text book . . .”

Student Testimonials“. . . One the most important lessons I

can take from this experience is how to work in teams . . .”

“. . . All the skills I have learned will definitely help build my resume . . .”

“STUDENTfacturED provides great exposure to working in a regulated industry. This type of experience is unrivaled in any classroom I've ever seen.”

R. Kevin PeggFlorida State College at Jacksonville

The FSCJ Institute for Food Safety Biotechnology Program:

The Co-located CRO Model: R. Kevin Pegg, Florida State College at Jacksonville

Panel 1: Bioscience Business/Education Models 8:45am – 10:00am

The FSCJ Biotechnology programis an A.S. laboratory technician training with two tracks:an academic track that trains for Mayo Clinic, UF Shands;and a food safety testing track.The facility incorporates a “third-party” International testing company fully integrated into the program:Physically, financially, an academically.

Third Party Operator Model

• Eurofins Partnership:– Eurofins companies have about US $800 million annual sales and 7,000 employees across

150 sites in 29 countries• FSCJ is their only site in Florida• Portfolio of over 40,000 analytical methods, familiar brands such as MWG Operon

• Eurofins operates under a Memorandum of Understanding (MOU) with the college – Request for Information December 2008

• Request for Proposal April 2009– Negotiations throughout 2010

» Operations proceeded starting Summer 2010

– Launched officially in October 2010• First cohort of students in 2010/2011

• Eurofins pays rent based on local averages– Utilities are flat-rate– Returns share of profits based on modified “Lehman formula” (1M:2M:3M:4M:5M)– Agreements on IP, confidentiality, no exclusivity– Require TPO to intern and provide traineeships—

• But not agreement to hire students preferentially

Physically Integrated

Separate, Shared, and “mirrored” spaces

Current crop of studentsobserving Eurofins operationsvia view ports

Interns and trainees

Graduate, now full time

Academically Integrated

• Eurofins participates directly in program goals:– Curriculum reviews– SOP development– Advising students interested in the field– Advisory Boards

• College participates in industry directions– Standards development– Technical meetings– Best practices, materials

Intangibles• “Access”

– Steady stream of people--scientists and corporate– one would never encounter in a purely academic environment

• Trends– Eurofins called the FSMA legislation two years

before it was passed (hint: they wrote it)• Vendor credibility

– Ultra LC-MS

*IFS Phase2

Wendie JohnstonPasadena City College

Shared use wetlabMonth to month rent:Bench, desk, shelvesFully equipped lab

Tissue culture facilityNot for profit

Make Your Dream a RealityBCN Biosciences

Beginnings

ORIGINAL FUNDING: STATE LEGISLATION

FOUNDING MEMBERS: City, Industry, SoCalBio,

Community College, State University, Caltech

2004:- 500 sq ft in shared

use facility- 2 tenants

- Donated desks, casework, equipment

Today’s Story

2012: - 10,000+ sq ft- 16+ tenants

- 6 successful graduates

DetonCorp

Jobs CreatedCurrent tenants: 78

Graduates: 55 2 spin-offs

100% ownership of IPDiscounted supplies - BIOCollaboration - other tenantsHigh speed internetBasic office equipmentInterns availableResource listTrade Organization membership

Ophidion

Benefit to Tenant

Collaborations

Industry and university donations

Amgen Bruce Wallace Lab Program Saturday mentored workdays for high

school and college students - internship preparation

Suzanne WintersBioInnovations Gateway, Salt Lake City

BioInnovations GatewayGrowing Talent… Growing Business

Governor Herbert’s Agenda: Strengthen and grow Utah businesses Increase innovation, entrepreneurship and investment Increase national and international business Prioritize education to develop the workforce of the future

To provide life science start-up businesses a competitive edge by providing access to state-of-the-art space, equipment and talent in a cost-effective manner

To provide a workforce training program offering real-life, hands on experience in which students develop creative thinking and life science work skills in a product-driven environment

GOALS


Facilities Classrooms Teaching Labs Company Labs Shared Wet/Analytical Labs CAD Lab Machine Shop/Prototyping Lab

BiG

Students

BioManBioIn

Biomanufacturing /Biotechnology/Engineering

Industry driven curricula Concurrent enrollment with SLC Internships strongly encouraged

Incubator Companies

7 Company Labs Biotech & Medical Device Quarterly milestone evaluation CEO Lunch and Learn


Workforce Training Component-3 Tier Learning Model

1. Basic labs (yr 1)-- Research equipment (yr 2)2. BioInnovateTM – Student Design/Development

Projects Contract Manufacturing and Distribution 2b. Intern-in-Training

3. Resident company internships


Life Science Business Incubator Component

Companies must be committed to the workforce training

component of the facility Companies required to conduct seminars for

students/classes Companies strongly encouraged to hire student

interns (min 8 wks) If equipment scheduling conflicts occur, classes

take priority


BiG

Students

BioManCRO Benefits to Companies Access to high-end

equipment Availability to interns Grooming of potential

employees Affordable

office/laboratory space Contract research

capabilities

Benefits to Students/Teachers Internships/experiential learning Advanced skills Improved employability Professional development Networking w/ entrepreneurs Networking w/ chief scientists

Benefits to Utah New companies and jobs Trained workforce pipeline Serve as a national model


Incubator Metrics Currently 5 client companies- 28 new jobs created 5 patent filings, 2 license agreements, 4- 510(k)

submissions and 2 scientific publications Ongoing monthly CEO seminars/training Quarterly technical and business milestones

reviews with each client More than $11.5 Million investment capital

secured

First graduation June 2012!


Workforce Metrics 155 high school students 1000 9th graders (pipeline) Biomanufacturing curriculum revisions Injection Molding certification program Ongoing student seminar series and industry field

trips Senior project credit for BioInnovate/Internships Intern-in-Training program for students Completed BioInnovate project (Patent issued and

interested licensee)


Thank You!Suzanne Winters, Ph.D.Director, BioInnovations Gateway2500 South State StreetSouth Salt Lake, UT 84115phone: 385.646.4625fax: [email protected]

mailto:[email protected]

Panel 2: Challenges in setting up Business/Education Models

MODERATOR: Dr. Kathryn Birmingham, Dean, Florida State College at Jacksonville

PANELISTS:

Elizabeth Boedeker, St. Louis Community CollegeLinnea Fletcher, Austin Community CollegeTami Goetz, Former Biotechnology Program Chair, Salt Lake Community CollegeChuck Crabtree, Director - Iowa BioDevelopment, Indian Hills Community College

Panel 3: Educational & Workforce Development Impacts

of Business/Education Models

MODERATOR: Laurence Clement, Synergy-B2B Project Leader, Bio-Link

PANELISTS:

Candiya Mann (by Skype), Senior Research Manager at Washington State UniversityPeggy Weeks, BioBench Evaluator, St. Louis Community CollegeAlicia Manfre, Hagerstown Community CollegeIan Rappold, student in St. Louis CC ProgramAdam Blaszczak, Salt Lake Community College

Panel 4: Economic/Business Impacts of

Business/Education Models

MODERATOR: John Carrese, Centers of Excellence/Bio-Link,City college of San Francisco

PANELISTS:

Beth Noonan, St. Louis County Economic CouncilMarc Vanacht, Trophomax, St. Louis Tim Nieman, CEO, Zien Medical, BioInnovations Gateway, Salt Lake CityTami Goetz, Governor’s Office of Economic Development, Salt Lake City

Open Mic Topic: Quality Assurance for National CRO/CMO Programs

Craig Caldwell (by Skype), Biotechnology Department Chair, Salt Lake Community

THANK YOU!

2012 bio link summit slides

Education

Transcript of 2012 bio link summit slides