1120 HPLC Brochure

easy.HPLC has never been so

Agilent 1120 Compact LC

Our measure is your success.

Introducing the Agilent 1120 Compact LC

EZChrom Elite Compact software makes it easy for all your users toset up and operate the system.

Simply a better value.Is your lab looking for better, more reproducible results for all your standard HPLC analyses, run after run

and day after day? Are you looking for an affordable, high quality solution that maximizes uptime, minimizes

maintenance and provides the highest return on your investment?

Here’s some good news: the new 1120 Compact LC from Agilent.

Now any lab can take advantage of Agilent’s unmatched combination of advanced instrumentation, versatile

software and application-matched columns and consumables. This robust new LC solution is designed to

optimize performance, while minimizing complexity. And because it’s from Agilent, it gives you the proven

quality and performance you expect from the industry leader, in your choice of five easy to own, integrated,

“all-in-one” configurations.

Easy to learn and use – for all users.

With simple, intuitive Agilent EZChrom Elite Compact

software and built-in self-diagnostics, the 1120 Compact

LC is easy to operate and easy to maintain. Because every

system is thoroughly tested in its final configuration before

shipping, startup is fast and trouble-free. Right out of the

box, even inexperienced or infrequent users can quickly

master the system and produce first-rate results.

Extraordinary results in a system optimized for everyday productivity.

Run-after-run, day-after-day reproducibility. Exceptional accuracy.

Superior precision. For all your routine applications – including

those that must comply with regulatory requirements – the 1120

Compact LC offers uncompromising LC performance.

Industry-leading quality and long-life Agilent reliability.

Why settle for “good enough,” when you can invest in quality?

With a 30-year history of success and an installed base of

more than 60,000 LC systems, Agilent has earned a worldwide

reputation for reliability and uptime under the most demanding

operating conditions.Time [min]

0 1 2 3 4 5 6 7 8 9 10 11

Abs

orba

nce

[mA

U]

0

200

400

600

Peak % RSD RT % RSD Area

1

2

3

4

0.05

0.08

0.09

0.09

0.22

0.30

0.19

0.09

1

2

3

4

Excellent reproducibility of retention times and areas from six repetitiveisocratic analyses of a standard sample – with 3 µL injection volume.

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Agilent’s 1120 Compact LC delivers the performance you are looking for and reliability you can count on – as well as today’s lowest cost of ownership!

A simply perfect choice for labs like yours.

The Agilent 1120 Compact LC was developed specifically to

address the needs of small- to medium-sized labs that are

mainly concerned with routine analyses using standard HPLC

methods. In keeping with its mission, the system delivers all the

performance needed to meet stringent regulatory demands –

while setting new standards for compactness, ease of operation

and serviceability.

To learn more about the Agilent 1120 Compact LC, visit www.agilent.com/chem/1120 3

Isocratic Pump

Autosampler

Column Oven

Variable WavelengthDetector

Isocratic Pump

Manual Injector

—


Gradient Pump

Manual Injector

—


Gradient Pump

Manual Injector

Column Oven


Gradient Pump

Autosampler

Column Oven


Simply more in tune with your lab’s needs.Take a close look at the Agilent 1120 Compact LC and you’ll find everything you need for first-class results

and rewarding day-after-day productivity. And, because you’re too busy to worry about complicated features

your lab is unlikely to use, you’ll be pleased to find there’s nothing there you don’t need.

Five standard configurations to fit your LC workflow

Solvent delivery

The optimized design of the pumping module used in the

Agilent 1120 LC ensures stable, virtually pulse-free solvent

flow up to 10 mL/min. Servo-controlled, dual floating pistons

enable variable stroke volume optimized for the selected flow

rate, and keeps maintenance to a minimum. Choose from

different configurations, including either an isocratic pump

or a gradient pump with up to two solvents and integrated

two-channel degasser.

Pump options

• Automated solvent selection valve for gradient pump –

combines two-out-of-four solvents for gradient formation

or for column flushing with different solvents.

• Continuous seal wash kit to prevent corrosion for

applications running buffer solutions with high salt

concentrations greater than 0.1 M.

Agilent’s LC detectors are fully compatible with the 1120 Compact LC. Additional external detection choices include: • Refractive Index (RID) • Fluorescence (FLD) • Evaporative Light Scattering (ELSD)

Degasser

The gradient pump includes an integrated dual-channel

degasser with continuous vacuum using Teflon AF technology,

which provides low internal volumes of 1.5 mL per channel.

The degasser eliminates baseline fluctuations and shortens

equilibration times.

Gradient pump and integrated degasser

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Isocratic Configurations Gradient Configurations

Column ovenAutosamplerManual injector Variable wavelength detector

Trace analysis of pesticide residues, showing a limit of detection(LOD) of less than 100 pg. The relative standard deviation is lessthan 0.08 % for retention times and less than 0.5 % for areas.

Manual injector

An easy to use, easy to maintain solution for low throughput

sampling, the manual injector includes a long-life Rheodyne

2-position, 6-port sample injection valve and standard 20 µL

loop. Front access to the valve facilitates easy sample injection

and straightforward exchange of sample loops.

Autosampler

The integrated autosampler is designed for reliability, safety,

and easy maintenance, and facilitates reliable injections from

0.1 to 100 µL. The unit delivers high precision as well as

excellent linearity over a wide volume range. The autosampler’s

flow-through design ensures that there is no loss of sample;

the entire sample drawn from the vial is injected. The standard

configuration offers a sample capacity of 100 2-mL vials;

alternatively, two half-trays each with 40 2-mL vials or 15

6-mL vials can be used.

Column oven

The 1120 Compact LC's available column oven houses a single

column, and provides accurate, stable column temperature

from 10 degrees above ambient to 60°C, for applications

where retention time reproducibility and separation quality

improve above ambient temperatures.

Variable wavelength detector

Featuring simplified optics for high sensitivity, low baseline

drift and wide linear range, Agilent’s variable wavelength

detector not only lowers your detection limits; it lowers

your cost of ownership with easy front access for

fast lamp and flow cell replacement.


0 1 2 3 4 5 6 7 8 9 10 11 12 13

0

5

10

15

20

25

30

35

40

45

11.6

86

5.15

45.

309

8.80

3

Impurities

Ibuprofen

Time [min]

Abs

orba

nce

[mA

U]

Analysis of a pharmaceutical preparation, showing the activeingredient ibuprofen and three earlier-eluting impurities.

Time [min]0 2 4 6 8 10 12 14

Abs

orba

nce

[mA

U]

0

10

20

30

40

1

23

5

4

9

76

8

Terbuthylazine8

9

7

6

5

4

3

2

1

Propazine

Chlortoluron

Diuron

Prometryn

Simazine

Cyanazine

Chloridazone

Metamitron

Peak Compound

Regulatory compliance – made easy.

EZChrom Elite Compact provides comprehensive tools

to help you address all the requirements of GLP/GMP

and 21 CFR Part 11 compliance. With built-in audit

trails, multi-user login security, user permissions, and

electronic signatures, the software made easy for your

laboratory to operate in any regulated environment.

Simply easier to learn, to use – and to live with.

Quick access to common tasks. View instrument status, cur-rent data and run queue on a single screen—and perform a runwith just a couple of mouse clicks.

A complete, integrated software solution

With the bundled EZChrom Elite Compact software, it’s easy

to put all of the capabilities of the 1120 Compact LC to work

in your lab. A fast, powerful chromatography data system,

EZChrom Elite Compact provides full control of two 1120

Compact LCs from a single PC. EZChrom Elite Compact

includes comprehensive data processing, flexible reporting

and the full range of capabilities you would expect from a

modern chromatography work station.

Scalable from a single user to a whole enterprise.

As a scalable part of the Agilent informatics portfolio, your EZChrom Elite Compact software can grow as your lab grows. Upgrade to

EZChrom Elite Workstation and add control for over 330 chromatographic components from more than 25 vendors. Expand further

to full client-server deployment, or all the way to Agilent’s enterprise-wide OpenLAB solution. No matter how your lab’s needs evolve,

your data, methods, sequences and reports will still be readable. And, because the user interface is the same across the full product

line, you won’t have to retrain your operators.

From EZChrom Elite Compact to Workstation to Client/Server, EZChrom Elite software can be easily scaled up to meet the changing needs of a growing lab.

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Lab Monitor & Diagnostic Software alerts you to problems before they happen. Now you can detect instrument problems before

they occur and schedule a convenient time to solve

the problem without it impacting your analysis. This

is facilitated by an easy-to-use package included

in your system, Lab Monitor and Diagnostics software,

that continuously monitors your instrument.

From a “lab-at-a-glance” screen that displays

a snapshot of all connected 1120 Compact LC

instruments, to guided diagnostics tests and easy

to perform maintenance routines, to a built-in suite

of user information and help, Lab Monitor and

Diagnostics software provides all the information

a user needs in one convenient place at one time

thus enabling you to maximize your instrument’s

efficiency and productivity.

Agilent columns and supplies—an extra measure of reliability and confidence.

Whatever your lab is analyzing, every method requires

day-to-day reproducibility and superior reliability. To deliver

optimal performance with all your samples and mobile

phase, the Agilent ZORBAX Eclipse Plus columns give you

the performance and consistency you're looking for. These

columns deliver excellent peak shape under a wide range

of operating conditions for the highest quality, reproducible

results.

Try the Eclipse Plus C18 column included with your 1120

Compact LC. You'll appreciate its superior qualitative and

quantitative performance. And if you need other columns

the complete ZORBAX product line will have a choice for

your application. ZORBAX columns and Agilent supplies for

your new compact LC – the products you need to achieve

peak productivity – day after day, and year after year.

Maximize your uptime with Agilent’s customer-enabled service and support features.

The 1120 Compact LC’s integrated hardware and software

design features provide a completely new level of operational

simplicity. There’s a guided system set-up so that you can get

your new 1120 Compact LC up and running without having

to schedule a visit by an Agilent service representative.

Of course, Agilent’s world class customer service engineers

and certified support partners are available to provide a full

range of Agilent services, including installation, familiarization,

training, maintenance, contractual repair, and regulatory

compliance support.


The Agilent Value Promise–10 years of guaranteed value

In addition to continually evolving products, we offer something

else unique to the industry—our 10-year value guarantee.

The Agilent Value Promise guarantees you at least 10 years of

instrument use from your date of purchase, or we will credit you

with the residual value of that system toward an upgraded model.

Not only does Agilent ensure a safe purchase now, we help

ensure your investment is as valuable to you in the long run.

The Agilent Service Guarantee

Should your Agilent instrument require service while covered by

an Agilent service agreement, we guarantee

repair or we will replace your instrument for free.

No other manufacturer or service provider offers

this level of commitment to keeping your laboratory running at

maximum productivity.

© Agilent Technologies, Inc. 2008Published March 1, 20085989-7372EN

For more information

Learn more:www.agilent.com/chem/1120

Buy online:www.agilent.com/chem/store

Find an Agilent customer center in your country:www.agilent.com/chem/contactus

Contact us:[email protected]

1120 HPLC Brochure

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