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2. RNA virus ( ) ..2002-2003 SARS Coronavirus ..2555 Novel Corona virus Middle East Respiratory SyndromeCoronavirus (MERS- CoV) 10-14 3. 2012 4. ECDC 30 2557 30 2557 424 131 30.90 : 2: 1 49 Median age 50 ( 1- 94 ) 94 ( 393 ) 19 51(177 ) 40 5. Middle East Europe Saudi Arabia: 342 105 United Arab Emirates: 49 9 Jordan: 5 3 Oman: 2 2 Kuwait: 3 1 Egypt: 1 UK: 4 3 Germany: 2 1 France: 2 1 Italy: 1 Greece: 1 Africa Tunisia: 3 1 Asia Malaysia: 1 1 Philippines: 1 6. We are in week 110 of the MERS-CoV outbreak event, that's 2.12 years and 386 cases including approximately 113 deaths (PFC of 29.3%, the lowest to date) since the first known cases became ill in Mar of 2012. 7. 29 2557 MERS-CoV (Middle East respiratory syndrome coronavirus) match MERS-CoV nonhuman primate cells 8. 31 ( 60.8) MERS-CoV (Human to human transmission) (Cluster) (Family contact) (Hospital setting) 26 MERS- CoV 21.76 9. Healthcare worker (HCW) numbers have risen sharply (see below) during the April outbreak to a total of 84 detections, 7% of whom have died. 10. (Asymptomatic or mild case) 13.5 380C 28 Oxygen saturation (SpO2) 90 1 (Severe Acute Respiratory Distress Syndrome: ARDS) 11. Centers for Diseases Control 47 98 72 26 12. (Severe Acute Respiratory Infection: SARI) MERS-CoV 13. : 2 Nasopharyngeal Aspiration Influenza A,B,Influenza A virus subtypes H1,H3,H5, H5N1,RSV,Parainfluenza viruses, rhinoviruses, adenoviruses,human metapneumoviruses,non-SARS coronaviruses Nasopharyngeal Aspiration 14. MERS-CoV Nasopharyngeal Aspiration reverse-transcriptase polymerase chain reaction (RT-PCR) 15. a. i. MERS-CoV Ribavirin Ribavirin (hemolysis) 16. ii. Oseltamivir b. (Antibiotics) 17. a. b. supplemental oxygen therapy SpO2 < 90 5 SpO2 > 90 SpO2 > 92-95 c. 18. Infection Control (Hospital Seting), (Family cluster and closed contact cluster) (Isolation Precautions) Standard precautions Hand hygiene, Respiratory hygiene and cough etiquette, Safe injection practices 19. Infection Control contact precaution droplet precaution MERS-CoV droplet nuclei or tiny droplet 1 droplet precaution Airborne precaution Airborne infection isolation room (AIIR) () 20. Standard Precautions Transmission Precautions Airborne Precautions TB, Chicken pox, Measle, SARs Droplet Precautions Rubella, Pertussis, Meningoccal Avian flu, H1N1 Contact Precuations , , , Hand hygiene Personnel protective barriers (PPE) CSSD 21. Infection Control Surgical Mask Mask Surgical Mask (aerosol) N95 Goggle face Shield (Gown) 22. Infection Control (Respiratory Etiquette) 23. (H5, H7) MERS-CoV (Middle East Respiratory Syndrome Coronavirus) 24.