© life_edu Lecture 26 Part Ic. Animal and Human Cloning and Genetic Engineering Issues in...
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© life_edu Lecture 26 Part Ic. Animal and Human Cloning and Genetic Engineering Issues in Biotechnology: The Way We Work With Life Dr. Albert P. Kausch life edu.us Medical Biotechnology
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Transcript of © life_edu Lecture 26 Part Ic. Animal and Human Cloning and Genetic Engineering Issues in...
© life_edu
Lecture 26
Part Ic. Animal and Human Cloning and Genetic Engineering
Issues in Biotechnology:The Way We Work With Life
Dr. Albert P. Kausch
life edu.us
Medical Biotechnology
Issues in Biotechnology:Biotechnology, Our Society and Our Future
OnCampus LiveOnCampus LiveBCH 190, MIC 190, AFS 190, NRS 190, PLS 190BCH 190, MIC 190, AFS 190, NRS 190, PLS 190
OnLine BCH 190OnLine BCH 190
A Sweeping General Survey on Life and BiotechnologyA Public Access College Course
The University of Rhode Island
Kimberly Nelson
Issues in Biotechnology:The Way We Work With Life
Dr. Albert P. Kausch
life edu.us
© life_edu
A Sweeping General Survey on Life and Biotechnology
The University of Rhode Island
Issues in Biotechnology:The Way We Work With Life
Dr. Albert P. Kausch
life edu.us
BCH 190BCH 190 Section II.
The Applications of Biotechnology
Where is DNA in a cell?
• All of the information for each protein in a cell is in it’s DNA• All of the information that codes for a complete organism is in DNA
Cloning AnimalsCloning and Genetic Engineering in Animals
Genetically Engineered AnimalsCloning and Genetic Engineering in Animals
How to Clone
Nuclear transfer procedures
This shows:
• All of the information that codes for an organism is in it’s DNA
• All of the DNA is the same in every cell
• DNA is located in the nucleus of the cell
An Organism can be cloned by transferring it’s DNA to an egg cell
Promoter Coding Sequence Terminator
Could we Genetically Engineer Cloned Animals?
Controlled expression“making protein”
Your favorite gene
VaccinesAntibodiesHigh Value ProteinsSpider Silk in Goats Milk
Stop transcriptionMessage stability
Genetically Modified somatic nuclei could be implanted into unfertilized eggs to create a genetically modified clone
Genetically Modified somatic nuclei could be implanted into unfertilized eggs to create a genetically modified clone
Transgenics and Cloned Animals
What is cloning?• A process whereby all members are directly descended
(asexually) from a single organism by……(various ways)
• Demonstrates that all the information required for an organism and its development are in the a single cell
Where is DNA in a cell?
• All of the information for each protein in a cell is in it’s DNA• All of the information that codes for a complete organism is in DNA
Principle• All cells are derived from a zygote
• All have the same genetic makeup
• All have the potential to develop into an individual
UCONN Clones
Many animals can now be cloned
sheepcattleporcinemice ratsmulesfrogs primates?
And Genetically Engineered
Primates2012
And Genetically Engineered
Many animals can now be cloned
Issues in Biotechnology
The ‘cloning’ of plants was demonstrated by Steward in 1958 at Cornell Univ. showing that plants could be grown back from a single cell. This ability is called “totipotency” and like the more recent examples of animal cloning, demonstrates:
(A) that all biological scientists are unethical and fraudulent
(B) that all of the DNA that codes for an entire organism is in every cell of that organism (C) Steward belonged to the group that called themselves the ‘Raeliens’ (D) the necessity to ban all types cloning(E) that the theory of evolution must be wrong
Could we Genetically Engineer Humans?
Your favorite gene
InsulinCancerAnti-OncogenesParkinson’sHuntington’sSCID
Beyond Therapy???
Promoter Coding Sequence Terminator
Controlled expression“making protein”
Stop transcriptionMessage stability
Cells from an amniocentesiscan be used for DNA sequence analysis. All of the genes for humans will be known.
Disease genes would be detected.
Cloned “correct” genes could be used for replacement.
Corrected nucleus could be delivered to an unfertilized egg.
Same baby without the defect.
Can humans be cloned and/or genetically engineered?Can humans be cloned and/or genetically engineered?
Could we Genetically Engineer Humans?
The Tay Sachs Dilemma
Do You Think We Do You Think We Should We Should We
Genetically Engineer Genetically Engineer Humans?Humans?
(A) yes(B) no(C) depends on the circumstance
Issues in Biotechnology
I would clone myself if that were possible.
(A) yes(B) no (C) undecided
The Possibilities of Human Cloning
To Clone or Not to Clone
For those who are interested in taking this For those who are interested in taking this course for college credit through the course for college credit through the
University of Rhode Island; University of Rhode Island; For more information please contact:For more information please contact:
[email protected]@gmail.com
CreditsCredits
Lectures by: Lectures by:
Edited by:Edited by:
Video Produced by:Video Produced by:
Thank You to The University of Rhode Island Thank You to The University of Rhode Island and all of the students of Issues in and all of the students of Issues in
Biotechnology over the yearsBiotechnology over the years
Dr. Albert KauschDr. Albert Kausch
Dr. Albert Kausch Dr. Albert Kausch and Kimberly Nelsonand Kimberly Nelson
Thaddeus WeaverThaddeus Weaver
