專 題 乾躁症 -----------------------蔡綵景藥師 新藥介紹- Xyzal...
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季刊 Vol.17 Num.02 1. 專 題- 乾躁症 -----------------------蔡綵景藥師 2. 新藥介紹- Xyzal® --------------------施靜妤藥師 發行人：徐弘正 發行所：仁愛醫療財團法人 編 輯：藥劑部 (04)24819900-1139 101 年六月出刊
Transcript of 專 題 乾躁症 -----------------------蔡綵景藥師 新藥介紹- Xyzal...
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Vol.17 Num.02
1. - -----------------------
2. - Xyzal --------------------
(04)24819900-1139
101
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Vol.17 Num.02
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Sjogrens syndrome 40~50 19
Mucin
pH ()
90%
(lymphoma)
(Shirmers )
ANAanti-Ro/SS-Aanti-La/SS-B
Salagen (pilocarpine hydrochloride) Evoxac (cevimeline)
Salagen (
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)pilocarpine hydrochloride 5mg/tab Muscarinic receptor (M1,M3)
Salagen
1.
2.SJOGREN'S SYNDROME
1.Salagen tablets 5mg
3~6 15~30mg ( 2 ) 12
2.Sjogren's Syndrome Salagen tablets 5mg 6
(T )0.76Tmax1.25 Cmax 15 ng/ml
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pilocarpine
pilocarpine pilocarpine
(atropine, inhaled ipratropium)
pilocarpine (
)
C 1.
2.
3.4.
SPF 15
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A
- Xyzal
Xyzal film-coated tablets 5mg
5
levocetirizine dihydrochloride 5
Y
H1-
Receptor Antagonist Histamine
Histamine
()
5 ()
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5 ()
()
(creatinine clearance, CLcr) CLcr serum creatinine
CLcr =
( 0.85 for women )
()
(hay fever)
levocetirizine 5
levocetirizine cetirizine
935
levocetirizine 5
1% ( 1/10 1/100 )
( 1/100 1/1000 )
levocetirizine 5 (8.1%)(3.1%)
levocetirizine
CLcr (ml/min)
80 5079 30-49
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()(Hemodialysis) levocetirizine
levocetirizine
( CYP3A4 ) levocetirizine cetirizine pseudoephedrinecimetidineketoconazoleerythromycinazithromycinglipizide diazepam
theophylline (400 ) cetirizine (16%) theophylline cetirizine
levocetirizine
( cetirizine)
cetirizine
levocetirizine
piperazine
(creatinine clearance
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