лд заболеваний почек 2
Transcript of лд заболеваний почек 2
NATIONAL UNIVERSITY OF PHARMACY Department of Clinical Laboratory Diagnostic
ПіуріяПіурія
More than 60 in sight
E. coli in urine (different
multiplicity enlarge)
The crystals of uric acid
Urate crystals
Crystals of tripelphosfats
Amorphous phosphate crystals
Crystals urine acid ammonium
Crystals phosphate of lime
Oxalate crystals
Crystals of cholesterol and bilirubin
Characteristics of the glomerular filtration rate
Normally, men - 120 ± 25 ml / min, for women - 95 ± 20 ml / min
In violation of the outflow of urine appears fever, symptoms of intoxication, leukocytosis, leukocyte shift to
the left, increasing SHOЭ and anuria
«... The problem of the safety and efficacy of medicinal products is becoming increasingly
important worldwide. This is due to the introduction of the medical practice of a large number of pharmacological agents, irrational
use of medicines, medical errors ... »
World Health Organization, 2006
Humanitarian disasters related to drugs:1937 - Mr. sulfanilamide in diyetylenhlykoli1961 - thalidomide1983 - zomepyrak1983 - osmozyn1982 - benoksaprofen2001 - tseryvastatyn2005 - problem koksybiv2006 - problem antidepressants
Nephrotoxicity drugs or "drug nephropathy" - direct or indirect
(via the immune response) poshkodzhuyacha effect of drugs on urinary system and, above all,
on tubular and glomerular apparatus
Nephrotoxicity drugs or "drug nephropathy" - direct or indirect
(via the immune response) poshkodzhuyacha effect of drugs on urinary system and, above all,
on tubular and glomerular apparatus