SCIENCE.NEW SENIoS. FSRIDAY, JULY 6 1945 SUBSCRIPTION, $6.0&VOL. 102, NO. 2636 F J SINGLE COPIES, .15

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MARSHALL'S Introduction to Human AnatomySecond Edition!-As an introductory presentation of elementary human anatomy, this texthas achieved wide acceptance. The author's aim has been to encourage the student to thinkof anatomy in relation to life and as such this may be called a "functional anatomy." ByCLYDE MARSHALL, M.D., formerly Assistant Professor of Anatomy, Yale University. 388pages, 54" x 74", with 257 illustrations, many in colors. $2.50.

CRANDALL'S Introduction to Human PhysiologyThird Edition!-The functions of the human body are here described with the touch of ateacher keenly conscious of what makes the student learn. Intricate processes are reduced.to easily comprehended descriptions. Life-like applications are frequently called forth toimpress more forcefully essential fundamentals. By LATHAN A. CRANDAL, JR., M.D., PH.D.,Chief of Division of Physiology and Professor of Physiology, College of Medicine, Universityof Tennessee. 388 pa.ges, 54" x 7V", with 113 illustrations. $2.25.

WEATHERWAX' Plant BiologyStressing the physiological and ecological viewpoints, Professor Weatherwax lays down asound foundation on which the student may build a thorough knowledge of plant biology.The selection of material has been so calculated as to make the text completely adaptable toall regions of the country. By PAUL WEATHEWAx, Professor of Botany, Indiana Univer-sity. 455 pages, 51' x 8V', with 417 illustrations on 182 figures. $3.25.

HARROW'S Textbook of BiochemistryThird Edition!-Little need be- said about this text. Its unusually wide use bespeaks itsexcellent and unusual coverage of the fundamental facts of biochemistry. By BENJAMINHARROW, PH.D., Professor of Chemistry, The City College, College of the City of New York.537 pages, 6"x9", illustrated. $4.00. Dr. Harrow and Associates have also prepareda Laboratory Manual (Second Edition) for use with this text or any other standard text.132 pages, 6"x 9", illustrated. Wire-O-binding. $1.50.

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SCIENCE-ADVERTISEMENTS VOL. 102, No. 2636

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SCIENCE-ADVERTISEMENTS VOL. 102, No. 2636

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8 VOL. 102, No. 2636SCIENCE-ADVERTISEMENTS

SCIENCE

VOL. 102 FRIDAY, JULY 6, 1945 No. 2636

On the Hr Factor and the Rh Genetic Theory: DR. The Reaction of Vitamin A- with Lieberman-PHILIP LEvINE ......................................... 1 Burchard Reagent: EUGENE D. ROBIN.Opinion

152 of the International Commission of ZoologicalScientific Events: Nomenclature: WILLIAM F. RAPP, JR. ScientificThe Ipatieff High Pressure and Catalytic Labora- Papers for Europe: P.oFESsoR T. D. A. COCKRELL 16tory of Northwestern University; New Lecture Scientific Books:Boom Visual Aids at Colorado Agricultural andMechanical College; The New England Association Mankind: DR. CLARK WISSLER. General Chem-of Chemistry Teachers; Ware Cattell vs. The Amer- istry: PROFESSOR CECIL V. KING. Books Received 19ican Association for the Advancement of ScienceSettled for $7,500 by Consent Judgment ........................ 4 Science News ........... 10

Scientific Notes and News ................... ........................ 6 Index to Vol.CI........... i

Special Articles:SCIENCE: A Weekly Journal, since 1900 the official

Lycopersicin, a Fungistatic Agent from the Tomato organ of the American Association for the AdvancementPlant: DR. GEORGE W. IRVING, JR., DR. THOMAS of Science. Published by the American Association forD. FONTAINE and DR. S. P. DOOLITTLE. Asper- the Advancement of Science every Friday at Lancaster,.gillus Ustus: JOSEPH M. KURUNG. The Effect of Pennsylvania.Cysteine on Streptomycin and Streptothricin: DRLR. G. DENKELWATER, M. A. COOK and DR. MAX Editors: JOSEPHINE OWEN CATTELL and JAQUESTISHLER. The Mechanism of Pain in Trigeminal CATTELL.Neuralgia: RICHARD C. KARL, GEORGE E. PEABODY Policy Committee: MALCOLM H. SOULE, ROGER ADAMS

andDR.HAROLDG. WOLFF ..................... 9...................... 9andWALTER R. MILES.Advertising Manager: THEO. J. CHRISTENSEN.

Scientific Apparatus and Laboratory Methods:Communications relative to articles offered for publication

Synthetic Latex as Injection Mass for Closed Ves- should be addressed to Editors of Science, 34 Gramercy Park,sels: DR. JAMES M. SANDERS. A New Laboratory New York 3, N. Y.

Communications relative to advertising should be addressedShellac: PROFESSOR. THEODOR.E KoppANqyi..............14 to THaEo. CHRISTENSEN, Advertising manager, Smithsonian

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and to all matters of business of the Association should beInactivation of the Irritant Toxicants of Poison Ivy addressed to the Permanent Secretary, A.A.A.S., Smithsonianand Poison Oak: JAMES B. MCNAIR. The Names Institution Building, Washington 25, D. C.of Fossil Men: PROFESSOR F. GAYNOR EVANS. Annual subscription, $6.00 Single copies, 15 cents

ON THE Hr FACTOR AND THE Rh GENETIC THEORY

By Dr. PHILIP LEVINEORTHO RESEARCH FOUNDATION, LINDEN, N. J.

IN the recent discussions on the genetics of the. Rhmultiple alleles, no provision is, as yet, made forthe role of a gene determining the Hr factor. 2 Thisagglutinable property was described very early in thecourse of the studies on the pathogenesis of erythro-blastosis fetalis.3 It was advisedly designated byLevine4 as Hr (reversal of the letters Rh) because ofpeculiar relationship to a special variety of anti-Rhsera, now designated anti-Rh'. This is indicated inTable 1, which gives, at the same time, the four sub-

1 R. R Race, G. L. Taylor, K. E. Boorman and B. E.Dodd, Nature, 152: 563, 1943.

2 A. S. Wiener, SCIENCE, 100: 595, 1944.3 P. Levine, L. Burnham, E. M. Katzin and P. Vogel,

Am. Jour. Obstet. and Gynec., 49: 925, 1941.4P. Levine, Yearbook of Path. and Immunol., 508,

1941.

types of Rh and their frequencies resulting from thereactions of anti-Rho and anti-Rh' sera.

From the beginning of the studies on erythroblas-tosis fetalis, Levine has held to the view that therelationship of the anti-Hr and anti-Rh' sera isanalogous to that of anti-M and anti-N sera. Inother words, only three types of reactions are ob-served, and in both systems bloods failing to reactwith both anti-sera were never found. It was onlyafter hundreds of bloods were tested that the termHr and anti-Hr were designated. These results were

not published more fully because it was clear that thefirst anti-Hr serum was of weak activity and gave too

many negative reactions.Subsequently, Race and Taylor described a similar