2002 Purine derivatives

Purine derivativesR 0540 Synthesis and Cyclic AMP Phosphodiesterase 4 Isoenzyme Inhibitor Activity of

Heterocycle Condensed Purines. — With the object of developing novel inhibitors of cyclic AMP phosphodiesterase a series of condensed purines are designed and synthe-sized. — (SUZUKI*, H.; YAMAMOTO, M.; SHIMURA, S.; MIYAMOTO, K.-I.; YAMAMOTO, K.; SAWANISHI, H.; Chem. Pharm. Bull. 50 (2002) 9, 1163-1168; Dep. Synth. Chem., Fac. Pharm. Sci., Hokuriku Univ., Kanazawa 920, Japan; Eng.) — M. Paetzel

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