Post on 03-Jan-2016
Risk factors of acute pancreatitis: An ethnic difference
2015/03/30
埔里基督教醫院不分科住院醫師
何御彰
Introduction
Increasing incidence rate of acute pancreatitis 4 to 70 per 100,000 population
Pancreas 2014,43:1117-1122
Increases by an annual average of 1 to 5%Pancreas 2012,41:696-702
Risk factor of acute pancreatitis Cigarette smoking in Western countries
Am J Epidemiol 2008,168:932-937
Arch Intern Med 2008,168:649-656
Alcohol drinking in TaiwanPancreas 2014,43:1117-1122
Introduction
Study from Australia Higher rate of alcohol-related acute pancreatitis
Aust J Rural Health 2001,9:134-137
The aim of the study To investigate the differences in risk factors between Taiwanese
aborigines and non-aborigines
Materials and Methods
Participants Recruitment
Puli Christian Hospital (PCH) January, 2006 to December, 2014 International Classification of Diseases 577.0
Exclusion Re-admission Nationality other than Republic of China
Materials and Methods
Demographic characteristics Age / Gender / Body mass index
Social habitus Alcohol drinking / Betel nut chewing / Cigarette smoking
Biochemical properties Amylase / Lipase / Triglyceride / Uric acid / Calcium
Risk factors Alcohol-related / Gallstone / Hypertriglyceridemia Distal CBD obstruction / Hypercalcemia / Unknown
Materials and Methods
Statistical analysis Two tailed unpaired student’s t test
Age / BMI Amylase / Lipase / Triglyceride / Uric acid / Calcium
Pearson’s chi-squared test and Fisher’s exact test Gender Habitus Risk factor of acute pancreatitis
Result
Result
Result
Discussion
Demographic characteristics & Social habitus Aborigines
Younger Higher female-to-male ratio More habitus of alcohol drinking
Major issue of public health in Taiwanese aborigines More readily accessibility to alcohol Stress of marital life
Alcohol Clin Exp Res 1995,19:81-91
Soc Psychiatry Psychiatr Epidemiol 2013,48:955-963
Discussion
Biochemical properties Aborigines
Higher uric acid level Possible explanation
More alcohol consumption More vulnerability of hyperuricemia at a genetic level
Am J Hum Genet 2004,75:498-503
Higher uric acid level in smoking patients with pancreatitisPrzegl Lek 2013,70:809-812
Discussion
Risk factors Aborigines
More alcohol-related acute pancreatitis Culturally adapted intervention
Motivational care planningAust J Rural Health 2009,17:174-182
General practitioners trainingAust J Rural Health 2013,21:72-79
Discussion
Limitation Inadequate information of alcohol drinking Lack of easily medical accessibility Critical condition with immediate referral Extensive risk factor surveys were not conducted for everyone
Conclusion
Taiwanese aborigines are more susceptible to alcohol-related pancreatitis than non-aborigines.
The importance of public health education and effective strategy to prevent them from alcoholism cannot be overemphasized
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