Research and teaching with Research and teaching with blogs and wikis blogs and wikis

Jean-Claude.Bradley@drexel.eJean-Claude.Bradley@drexel.edudu

Feb 23, 2007Feb 23, 2007Drexel University Chemistry Department

Philadelphia Area Educational Technology Conference

Where is Science headed?Where is Science headed?

WE ARE HEREWE ARE HERE

The Robot ScientistThe Robot Scientist

How will this happen?How will this happen?

Self-organizing reduntant processesSelf-organizing reduntant processes Agents can participate with zero or Agents can participate with zero or

near-zero cost (free hosted services)near-zero cost (free hosted services) Fully Open Access (Read and Write)Fully Open Access (Read and Write) Publication of all aspects of the Publication of all aspects of the

scientific process: Open Source scientific process: Open Source Science / Science / Open Notebook ScienceOpen Notebook Science

How can machines know what How can machines know what is important?is important?

Ask the humansAsk the humans

UsefulChem BlogUsefulChem Blog

What chemists think is What chemists think is important in 2005important in 2005

Find-A-DrugFind-A-Drug

Diketopiperazine LibraryDiketopiperazine LibraryEvolves to: on pot Evolves to: on pot

Ugi Ugi reaction/cyclizationreaction/cyclization

First iteration: First iteration: Solid Support Solid Support

SynthesisSynthesis

The Molecules BlogThe Molecules Blog

The Experiments BlogThe Experiments Blog

Comments from peersComments from peers

The UsefulChem WikiThe UsefulChem Wiki

Telling the story of the failuresTelling the story of the failures

Experiments moved to wikiExperiments moved to wiki

Experiment HistoryExperiment History

Experiment EditsExperiment Edits

Third Party Time-Stamp on Third Party Time-Stamp on Experiment VersionsExperiment Versions

Monitoring experimental Monitoring experimental progressprogress

How are people finding our How are people finding our experiments?experiments?

Molecules found by InChIMolecules found by InChI

Automation in UsefulChemAutomation in UsefulChem

CMLRSS feed on BioclipseCMLRSS feed on Bioclipse

CMLRSS feed on BloglinesCMLRSS feed on Bloglines

Open science connectivityOpen science connectivity

More info on open source science here

http://usefulchem.wikispaces.com

Extending the interaction Extending the interaction outside of scienceoutside of science

usefulchem.blogspot.comusefulchem.blogspot.com

The blog as an integrative The blog as an integrative tooltool

usefulchem.wikispaces.com/Exp049usefulchem.wikispaces.com/Exp049

The wiki as the laboratory The wiki as the laboratory notebooknotebook

usefulchem.wikispaces.com/Exp049 (2 usefulchem.wikispaces.com/Exp049 (2 min)min)

Graphical Mining of Data with Graphical Mining of Data with JSpecViewJSpecView

neurodatabase.orgneurodatabase.org

Raw Experimental DataRaw Experimental Data

Selected Experiments (some Selected Experiments (some failed)failed)

Orgprepdaily.wordpress.comOrgprepdaily.wordpress.com

Orgprepdaily.wordpress.comOrgprepdaily.wordpress.com

Vendor ReliabilityVendor Reliability

Generalized ProtocolsGeneralized Protocols

Openwetware.orgOpenwetware.org

Lab Notebook for intra-group Lab Notebook for intra-group communicationcommunication

Openwetware.orgOpenwetware.org

Discussing HypothesesDiscussing Hypotheses

RRResearch.blogspot.comRRResearch.blogspot.com

Writing Code for the Writing Code for the Automation ComponentAutomation Component

Also – Rich Apodaca, Christoph Also – Rich Apodaca, Christoph Steinbeck, Peter Murray-RustSteinbeck, Peter Murray-Rust