Michael W Hodin, Ph.D.

Executive Director, Global Coalition on Aging

Managing Partner, High Lantern Group

Alzheimer’s: A 21st Century Fiscal and

Social Imperative

“No other force is likely to shape the future of

national economic, health, public finances, and

policymaking as the irreversible rate at which

the world’s population is aging.”

—Standard & Poor's

“Global Aging 2010: An Irreversible Truth”

2

3

Substantial Growth of Older Population

609 million 1 billion 2 billion

0%

20%

40%

60%

80%

100%

2000 2020 2050

60+

15-59

0-14

2 billion over 60

0%

20%

40%

60%

80%

100%

2050

60+

15-59

0-14

Most Dramatic Growth Among 85+ Population

The risk of dementia jumps from 1 in 8

for those over the age of 65 to 1 in 2.5

for those over 85.

4

191 million

people over

85 by 2050

60+ Population

60-84 Years Old

So

urc

e: W

orldM

appe

r.o

rg a

nd

Age

Wave

estim

ate

s

The Number of Alzheimer’s Cases 1900 (est.)

Note: Each dot represents 100,000 cases of Alzheimer’s 5

So

urc

e: W

orldM

appe

r.o

rg a

nd

Age

Wave

estim

ate

s

Note: Each dot represents 100,000 cases of Alzheimer’s

The Number of Alzheimer’s Cases 1950

6

So

urc

e: W

orldM

appe

r.o

rg a

nd

Age

Wave

estim

ate

s

Note: Each dot represents 100,000 cases of Alzheimer’s

By 2000, we have an epidemic

7

So

urc

e: W

orldM

appe

r.o

rg a

nd

Age

Wave

estim

ate

s

Note: Each dot represents 100,000 cases of Alzheimer’s

By 2050, Alzheimer’s transforms

from health crisis to fiscal nightmare

8

Today 2030 2050

Co

sts

& P

revale

nce

$604 billion;

1% of Global GDP

With investment

in treatment, care,

and prevention

Without investment

in treatment, care,

and prevention

115 million cases

9

Costs and Rates Will Soar Without a Breakthrough

36 million cases

Dementia is a Global Challenge

10

“The consequences of dementia for societies and

economies are devastating everywhere, in high-income

countries and low- and middle-income countries alike..”

-The World Health Organization

“Nearly two-thirds of all people with dementia live in low

and middle income countries, where the sharpest

increases in numbers are set to occur.”

- Alzheimer’s Disease International, World Alzheimer Report 2010

11

Dementia is Becoming a Top Priority

“Dementia doesn’t just affect individuals.

It also affects and changes the lives of family members.

Dementia is a costly condition in its social,

economic, and health dimensions.”

—WHO Director-General Margaret Chan

“The Obama administration has announced a bold research

program to test whether a drug can prevent the onset of

Alzheimer’s disease...the payoff could be huge.”

—New York Times, 20 May 2012

“Dementia is a ticking time bomb.”—Dr. Peter Piot

Dementia Is on the Global Agenda

United Nations

NCD

Outcomes

Document

WHO

Standalone report

on Alzheimer’s

Alzheimer’s

Disease

International

Reports

Global Coalition

on Aging

Links to AD Driving

Challenge

OECD

Meetings and

Agendas

Growing Global

Media Interest

ADNI

Collaboration

12

But We Are Not Where We Need To Be.

13

14

100% Incurable

&

100% Fatal

Alzheimer’s Disease is

15

How Do We Advance Progress?

New Care Models

Re-invent Care that draws on the best private sector innovation

Remove Stigma

We think progress is impossible

Improve Regulatory Environment

Stuck in 20th century regulatory models

Motivate Patient Advocacy

Create a Movement -- driven, motivated, political

16

New Care Models

Re-invent Care that draws on the best private sector innovation

Remove Stigma

We think progress is impossible

Improve Regulatory Environment

Stuck in 20th century regulatory models

Motivate Patient Advocacy

Create a Movement -- driven, motivated, political

How Do We Advance Progress?

17

New Care Models

Re-invent Care that draws on the best private sector innovation

Remove Stigma

We think progress is impossible

Improve Regulatory Environment

Stuck in 20th century regulatory models

Motivate Patient Advocacy

Create a Movement -- driven, motivated, political

How Do We Advance Progress?

18

New Care Models

Re-invent Care that draws on the best private sector

innovation

Remove Stigma

We think progress is impossible

Improve Regulatory Environment

Stuck in 20th century regulatory models

Motivate Patient Advocacy

Create a Movement -- driven, motivated, political

How Do We Advance Progress?

19

New Care Models

Re-invent Care that draws on the best private sector innovation

Remove Stigma

We think progress is impossible

Improve Regulatory Environment

Stuck in 20th century regulatory models

Motivate Patient Advocacy

Create a Movement -- driven, motivated, political

How Do We Advance Progress?