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Making the Food You Love a Healthier Choice™

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Thiscommunicationcontains“forward-lookingstatements”withinthemeaningofthesafeharborprovisionsoftheU.S.PrivateSecuritiesLitigationReformActof1995.Insomecases,youcanidentifythesestatementsbyforward-lookingwordssuchas“may,”“might,”“will,”“should,”“expects,”“plans,”“anticipates,”“believes,”“estimates,”“predicts,”“potential”or“continue,”thenegativeofthesetermsandothercomparableterminology.Theseforward-lookingstatements,whicharesubjecttorisks,uncertaintiesandassumptionsaboutus,mayincludeprojectionsofourfuturefinancialperformance,ouranticipatedgrowthstrategiesandanticipatedtrendsinourbusiness.Thesestatementsareonlypredictionsbasedonourcurrentexpectationsandprojectionsaboutfutureevents.Thereareimportantfactorsthatcouldcauseouractualresults,levelofactivity,performanceorachievementstodiffermateriallyfromtheresults,levelofactivity,performanceorachievementsexpressedorimpliedbytheforward-lookingstatements,includingthosefactorsdiscussedunderthecaptionentitled“RiskFactors”inourAnnualReportonForm10-K,alongwithourotherfilingswiththeU.S.SecuritiesandExchangeCommission.Wedonotassumeanyobligationtopubliclyproviderevisionsorupdatestoanyforward-lookingstatements,whetherasaresultofnewinformation,futuredevelopmentsorotherwise,shouldcircumstanceschange,exceptasotherwiserequiredbysecuritiesandotherapplicablelaws.

FORWARD LOOKING STATEMENTS

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Whatifthefoodsyoulovecouldimproveyourhealth?

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Who is Calyxt?Food ingredients for consumer health

Weare…

acompanydevelopinghealthierspecialtyfoodingredients……byleveragingcuttingedgesciencetodevelopfoodcropsthroughgeneeditingtechnologies

ConsumerNeedsHealthierfoodingredients

FarmerNeeds

CuttingEdgeGeneEditingTechnologies

andTechnicalExpertise

InnovativeProductDevelopmentCapabilities

IdentityPreservedSupplyChain

SpecialtyFoodIngredients

Howwearebuildingapathtomarket...

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Recent Investment Highlights

ü  CalynoTMHighOleicSoybeanOilisthefirstevergene-editedfoodproducttosuccessfullyundergoreviewbytheUSDAandFDAandbecommercializedintheU.S.

ü  CalynoHighOleicSoybeanOilisnowavailablefromoneoftheworld’slargestbroadlinefoodservicedistributors

ü  Soldoutofseedforthe2019growingseasonwith55,000Calyxtsoybeanacrescontracted,representinga3xgrowthcomparedto2018acres

ü  KemXGlobalrefininghigh-oleicsoybeanoil

ü  AmericanNaturalProcessorscrushingandprocessinghigh-oleicsoybeansü  AgtegraCooperativedistributingCalyxtHighOleicSoybean

ü  SuccessfulharvestofHigh-FiberWheatfieldtrialswithcommerciallaunchplannedasearlyas2022

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ProductPipeline

SoybeanProductsHighOleicSoybean

HighOleic/LowLinolenicSoybean

WheatProductsHighFiberWheat

OtherCropsImprovedQualityAlfalfa

ColdStoragePotato

ReducedBrowningPotato

ProductCandidate

PhaseI PhaseII PhaseIII

Commercial

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Calyno High Oleic Soybean Oil

•  80%oleicacid•  20%lesssaturatedfats•  Zerotransfatsperserving•  Similaroilprofiletooliveoil•  Upto3xincreasedfry-life•  Neutraltastedesiredbycertainfoodapplications

CalynoHighOleicSoybeanOilComposition2,3

OleicOilCompositionComparison2,3Status

Zero Trans Fats - Enhancing Health Attributes by Improving Oil Composition

1.  “WHOplantoeliminateindustrially-producedtrans-fattyacidsfromglobalfoodsupply,”May14,2018http://www.who.int/news-room/detail/14-05-2018-who-plan-to-eliminate-industrially-produced-trans-fatty-acids-from-global-food-supply

2.  Companydata3.  CodexAlimentarius,StandardsforNamedVegetableOils,CODEXSTAN210-1999

0

50

100

Commodity CalyxtHOSoybean

Linoleic Linolenic Saturated Oleic

15242731

52616980

0% 20% 40% 60% 80% 100%

SafflowerSoybean

SunflowerMaizePeanutCanolaOlive

CalyxtHOSoybean

Oleic Saturated Polyunsaturated

Ø  CommerciallaunchinQ12019Ø  Supplychainpartnershipsestablished

RegulatoryBackground

•  FDAbanontheadditionoftransfatstofoodproducts-firstphase2018

•  EliminationoftransfatsfromtheglobalfoodsupplyisaprioritytargetofWHO’sstrategicplan1

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Calyxt HO Soy Business Model High Oleic Soybean Value Chain has Three Revenue Opportunities

Calyxtcontractsfarmerstogrowhigholeicsoybeans

Calyxtcontractscrusherstoprocesshigholeicsoybeanstomealandoil

CalynoTM-Calyxtsellshigholeicsoybeanoil

Calyxtutilizesexistingseedproducerstoproducehigholeicsoybeans

GrainProduction Processing SaletoFoodIndustryCustomers

SeedProduction

Distributor

HOSoybeanOil

HOSoybeanMeal

HOSoybeanSeedsoldtogrowers

HOSoybeanMealsoldasproteinforanimalnutrition

HOSoybeanOilsoldtofoodservicedistributorsandfoodcompaniesasaspecialtyingredient

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Super-Charge Distribution - Example Agtegra collaboration improves logistics and de-risks supply-chain

IDPStorageandHandling

SeedDistributionandTransportation

PooledAgronomicAdvice

AccesstoLargeFarmerNetwork

•  Agtegraisaninnovativefarmerownedgrainandagronomycooperativeservingover6,300farmermembersacrossNorthandSouthDakota

•  8thlargestagretailerintheUnitedStates

•  CalyxtandAgtegraworktogethertoprovidefieldservicesforproperplacementandagronomicadviceduringthegrowingseason

•  AgtegradistributesCalyxtHighOleicSoybeanseedstothecooperative’sfarmermembersinSouthDakota

•  Agtegraprovideslogisticsandtransportationservicesforgrainshipments

•  StorageandhandlingofCalyxtHighOleicSoybeangrainatAgtegraundertheCalyxtSoybeanIdentityPreservedProgram

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0% 50% 100% 150%

Apples,raw,withoutskinCarrotsOrange

Commodityriceflour,brownCommodityoatflour,partiallydebranned

QUAKER,100%NaturalGranolaOatsandHoneyCommoditycornflour,wholegrain

Peas,green,rawCommoditywholewheatflour

Almonds,dryroastedKELLOGG'S,SPECIALKLowCarbLifestyleProtein

Calyxtwheatflour,wholegrain

%DailyValue

Dietaryfibercontentcomparison

High Fiber Wheat

Calyxt’sHighFiberWheatComposition5

CalyxtHighFiberWheatComparison4,5

Status/Timing

White Wheat Flour with Up to 3x More Fiber

•  CurrentlyinPhase2•  2018:SuccessfulfieldtestingofCalyxtHigh

FiberWheatFlour•  2020:Developmentofsupplychain•  2022:Anticipatedcommerciallaunch

AsingleservingofCalyxthighfiberflourmayprovideupto100%oftherecommendeddailyvalue

1.CodeofFederalRegulations(2012).Title21,Section101.54-Nutrientcontentclaimsfor“goodsource,”“high,”“more,”and“highpotency.”2.CodeofFederalRegulations(2012).Title21,Section101.76-Healthclaims:fiber-containinggrainproducts,fruits,andvegetablesandcancer.3.CodeofFederalRegulations(2012).Title21,Section101.77-Healthclaims:fruits,vegetables,andgrainproductsthatcontainfiber,particularlysolublefiber,andriskofcoronaryheartdisease.4.Calyxtinternalcalculation5.http://nutritiondata.self.com/

ü  “Highinfiber”contentclaim1ü  “Mayreduceriskofsometypesofcancer”

labelingclaim2

ü  “Mayreduceriskofcoronaryheartdisease”labelingclaim3

PotentialProductFeatures

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ReduceWaste

Insect/DiseaseResistance

HerbicideTolerance

ReduceInputslikenitrogen,phosphorus

IncreaseYield

A Paradigm Shift for Food Ingredients Our Technology Allows Us to Address Both Consumer and Farmer Needs

MOREOF…

LESSOF…

PlantProteins

Nutrients

Color,Flavor

DietaryFibers

GoodFats

Vitamins

SaturatedFatsTransFats Allergens Toxic

Compounds

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Trait Development Process

Revolutionary Trait Development Process Taking the lead in high-value crops through lower development costs and significantly shorter timelines

Phase I

1-2 years

Phase II

1-2 years

Field Validation & Testing

Phase III

1-3 years

Seed Production & Pre-Launch

Healthier Food needs

Market Launch

Creation of Genome-Edited Lines

Calyxt Trait Development Process vs. Traditional Trait Development:

ü  Significantly reduces development timelines

ü  Significantly reduces development costs

Trait Discovery

Months

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Accelerating Return on Investment Clear Metrics to Unlock Gross Margin Growth Opportunity

ConsumerProductLaunches

SupplyChainImprovements

FarmerProductLaunches

GrossM

argin

ü  CommercialLaunchofCalynointheUS

ü  GrowacresYOYü  Establishfoodcompany

customerfunnel

KeyFactorstoProfit

Growth

•  Improvedqualitytraitslaunchedwithout-licensingmodel

•  Newadditionalproducts

Time

•  Reach100,000acres•  regionalexpansion•  Introducenewvarieties

•  Scale(e.g.moreandlargercrushers)•  Nextconsumerproductlaunched(highfiberwheat)

ExpandGeography

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Investor Information

CLXT$85.7Million32.7Million

GoldmanSachs,Citi,Jefferies,WellsFargo,BMO,Ladenburg,NationalSecurities

investors@calyxt.com

Ticker(Nasdaq):

CashPosition1:

SharesOutstanding1:

CoveringResearchAnalysts:

Calyxtcorporateheadquartersandfarm-to-tablekitcheninRoseville,Minnesota–openedinSeptember2018

ContactUs:

1AsofMarch31st,2019

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Whatifthefoodsyoulovecouldimproveyourhealth?

Wouldyouevereatanythingelse?