Post on 22-Apr-2018
Federal law restricts Baytril 100 to use by or on the order of a licensed veterinarian. Extra-label use of Baytril 100 in food-producing animals is prohibited.
©2017 Bayer, Shawnee Mission, Kansas 66201Bayer, the Bayer Cross and Baytril are registered trademarks of Bayer.
All other products are trademarks of their respective owners.
BL171659
Feature: Concentration-dependent. Baytril® 100 (enrofloxacin) Injectable is concentration-dependent, delivering effective therapeutic drug concentrations with a single dose (12.5 mg/kg of bodyweight).
Benefit: The effectiveness of concentration-dependent drugs is dependent upon high drug levels which rapidly kill bacteria.
Feature: Bactericidal. Baytril 100 has a mode of action that actually kills the bacteria causing infection by destroying bacterial DNA and preventing bacterial replication.
Benefit: Cidal drugs kill bacteria, taking stress off the animal’s immune system so that it can work efficiently to clear the infection.
Feature: Effective. In cattle, Baytril 100 reaches therapeutic drug concentrations at the site of infection in the lung in 1-2 hours1 and reaches peak killing concentration levels in approximately 5 hours in the blood plasma1 and 7 hours in the lungs.1
Benefit: The sooner bacteria are killed, the faster a calf will feel better and get back to work eating.
your 1st-pull treatment for BRD
Make
For more information about Baytril 100 or to obtain a product label, call
Bayer Veterinary Services at +1 (800) 422-9874
or visit www.Baytril100.com.
1. Davis JL, Foster DM, Papich MG. (2007). Pharmacokinetics and tissue distribution of enrofloxacin and its active metabolite
ciprofloxacin in calves. J Vet Pharmacol Ther. 30(6):564-571
Invitation (neutral)Let’s take a look at how Baytril 100 works …
It’s the customer’s decision … so you can decide if Baytril 100 is a treatment option you’ll consider for your clients’ BRD management strategy.
ConfidenceBaytril 100 has a proven track record for 1st-pull treatment of BRD.
Cattle intended for human consumption must not be slaughtered within 28 days from the last treatment of Baytril 100.
Not all antibiotics work the same.Concentration-Dependent
(Concept Illustration)
Drug LevelBacterial Population
Drug Level
Num
ber o
f Bac
teria
MIC90
The effectiveness of concentration-dependent drugs is dependent upon high drug levels which rapidly kill bacteria.
Drug Level
Num
ber o
f Bac
teria
MIC90
Drug LevelBacterial Population
Time-Dependent(Concept Illustration)
Time-dependent drugs inhibit bacteria growth over time and require drug concentrations to remain above MIC at the site of infection for as much of the dosing interval as possible.
Cell: Penicillins Cephalosporins Excede® Naxcel®
DNA: Fluoroquinolones Baytril 100 Advocin®
Major Antibacterials: Modes of Action
Ribosomes: Tetracyclines
Bio-Mycin® 200 Fenicols Nuflor® Nuflor Gold® Resflor Gold®
Macrolides Micotil® 300 Draxxin® Zactran® Zuprevo®
Bacterial Cell
Baytril® 100 (enrofloxacin) Injectable is bactericidal. Its mode of action destroys the DNA of BRD-causing bacteria.
Bactericidal antibiotics kill infectious bacteria. Bacteriostatic antibiotics inhibit/slow the growth of infectious bacteria.
Bactericidal Bacteriostatic
Baytril 100 (enrofloxacin)
Advocin® (danofloxacin mesylate)
Nuflor® and Nuflor Gold® (florfenicol)**
Resflor Gold® (florfenicol and flunixin meglumine)
Excede® (ceftiofur crystalline-free acid)
Excenel® RTU (ceftiofur hydrochloride)
Naxcel® (ceftiofur sodium)
Penicillin
Draxxin® (tulathromycin)
Micotil® (tilmicosin)
Zactran® (gamithromycin)
Zuprevo® (tildipirosin)
Nuflor (florfenicol)**
Bio-Mycin® 200 (oxytetracycline)
Liquamycin® LA-200® (oxytetracycline)
Tim
e-De
pend
ent
Conc
entra
tion-
Depe
nden
t
Product Mode of Action Chart
**Nuflor has been reported to show bactericidal activities against certain bacterial strains (see Nuflor label for additional information).
Check-Off (Qualify)Identify if a Bayer Animal Health representative has been in recently:
Doctor, we all know Baytril 100 has been an effective treatment drug, but have you reconsidered your BRD protocols recently?
If YES, confirm and discuss benefits. If NO, engage/detail the customer as the primary contact.
CHECK-OFF &ECHO NOTES
Sound
Make Baytril 100 your 1st-pull treatment for BRD