Federal law restricts Baytril 100 to use by or on the order of a licensed veterinarian. Extra-label use of Baytril 100 in food-producing animals is prohibited.

©2017 Bayer, Shawnee Mission, Kansas 66201Bayer, the Bayer Cross and Baytril are registered trademarks of Bayer.

All other products are trademarks of their respective owners.

BL171659

Feature: Concentration-dependent. Baytril® 100 (enrofloxacin) Injectable is concentration-dependent, delivering effective therapeutic drug concentrations with a single dose (12.5 mg/kg of bodyweight).

Benefit: The effectiveness of concentration-dependent drugs is dependent upon high drug levels which rapidly kill bacteria.

Feature: Bactericidal. Baytril 100 has a mode of action that actually kills the bacteria causing infection by destroying bacterial DNA and preventing bacterial replication.

Benefit: Cidal drugs kill bacteria, taking stress off the animal’s immune system so that it can work efficiently to clear the infection.

Feature: Effective. In cattle, Baytril 100 reaches therapeutic drug concentrations at the site of infection in the lung in 1-2 hours1 and reaches peak killing concentration levels in approximately 5 hours in the blood plasma1 and 7 hours in the lungs.1

Benefit: The sooner bacteria are killed, the faster a calf will feel better and get back to work eating.

your 1st-pull treatment for BRD

Make

For more information about Baytril 100 or to obtain a product label, call

Bayer Veterinary Services at +1 (800) 422-9874

or visit www.Baytril100.com.

1. Davis JL, Foster DM, Papich MG. (2007). Pharmacokinetics and tissue distribution of enrofloxacin and its active metabolite

ciprofloxacin in calves. J Vet Pharmacol Ther. 30(6):564-571

Invitation (neutral)Let’s take a look at how Baytril 100 works …

It’s the customer’s decision … so you can decide if Baytril 100 is a treatment option you’ll consider for your clients’ BRD management strategy.

ConfidenceBaytril 100 has a proven track record for 1st-pull treatment of BRD.

Cattle intended for human consumption must not be slaughtered within 28 days from the last treatment of Baytril 100.

Not all antibiotics work the same.Concentration-Dependent

(Concept Illustration)

Drug LevelBacterial Population

Drug Level

Num

ber o

f Bac

teria

MIC90

The effectiveness of concentration-dependent drugs is dependent upon high drug levels which rapidly kill bacteria.

Drug Level

Num

ber o

f Bac

teria

MIC90

Drug LevelBacterial Population

Time-Dependent(Concept Illustration)

Time-dependent drugs inhibit bacteria growth over time and require drug concentrations to remain above MIC at the site of infection for as much of the dosing interval as possible.

Cell: Penicillins Cephalosporins Excede® Naxcel®

DNA: Fluoroquinolones Baytril 100 Advocin®

Major Antibacterials: Modes of Action

Ribosomes: Tetracyclines

Bio-Mycin® 200 Fenicols Nuflor® Nuflor Gold® Resflor Gold®

Macrolides Micotil® 300 Draxxin® Zactran® Zuprevo®

Bacterial Cell

Baytril® 100 (enrofloxacin) Injectable is bactericidal. Its mode of action destroys the DNA of BRD-causing bacteria.

Bactericidal antibiotics kill infectious bacteria. Bacteriostatic antibiotics inhibit/slow the growth of infectious bacteria.

Bactericidal Bacteriostatic

Baytril 100 (enrofloxacin)

Advocin® (danofloxacin mesylate)

Nuflor® and Nuflor Gold® (florfenicol)**

Resflor Gold® (florfenicol and flunixin meglumine)

Excede® (ceftiofur crystalline-free acid)

Excenel® RTU (ceftiofur hydrochloride)

Naxcel® (ceftiofur sodium)

Penicillin

Draxxin® (tulathromycin)

Micotil® (tilmicosin)

Zactran® (gamithromycin)

Zuprevo® (tildipirosin)

Nuflor (florfenicol)**

Bio-Mycin® 200 (oxytetracycline)

Liquamycin® LA-200® (oxytetracycline)

Tim

e-De

pend

ent

Conc

entra

tion-

Depe

nden

t

Product Mode of Action Chart

**Nuflor has been reported to show bactericidal activities against certain bacterial strains (see Nuflor label for additional information).

Check-Off (Qualify)Identify if a Bayer Animal Health representative has been in recently:

Doctor, we all know Baytril 100 has been an effective treatment drug, but have you reconsidered your BRD protocols recently?

If YES, confirm and discuss benefits. If NO, engage/detail the customer as the primary contact.

CHECK-OFF &ECHO NOTES

Sound

Make Baytril 100 your 1st-pull treatment for BRD