DENGUE HEMORRHAGIC FEVER (DHF)

DURGEMPUDI CHANDRA SEKHAR REDDY*, ARUN KUMAR CHADALAVADACHEBROLU HANUMAIAH INSTITUTE OF PHARMACEUTICAL SCIENCES,

CHOWDAVARAM, GUNTUR-19.

INTRODUCTIONDengue Hemorrhagic Fever is an acute infectious viral

disease usually affecting infants and young children.Causative agent: Aedes aegypti and Aedes albopictus.This disease used to be called break-bone fever because

it causes severe joint and muscle pain.Most favourable season for occurrence of this fever is mainly rainy season (sep &oct).

LIFE CYCLE

ETIOLOGY

Increase in urbanization in developing countries.

DHF will geographical spread by any one of four serotypes of Dengue viruses (DENV-1, 2, 3 and 4) and mainly it will spread by Aedes aegypti.

Population growth.

PATHOGENISISSIGNS & SYMPTOMS:

BRUISES CONJUNCTIVAL INFECTION

PETECHIE EPISTAXIS

UNDERLYING MECHANISM:

DIAGNOSIS:

PHYSICAL FINDINGS:HYPOTENSIONRED EYESRED THROATSWOLLEN GLANDS

TESTS INCLUDE:HEMATOCRITALTERED LIVER

ENZYMESPOSITIVE TORNIQUET

TESTSEROLOGIC STUDIES

RISK FACTORS:

• ENCEPHALOPATHY• RESIDUAL BRAIN DAMAGE• SEIZURES• LIVER DAMAGE

MANAGEMENTIsolation of patient and

treat the symptoms.Eliminate the vector by

Changing water and keeping containers closed.

Destroy breeding places of mosquitoes

Proper disposal of rubber tires, empty bottles and cans.

Residual spraying with insecticides.

REFERENCESHarrison’s Principles of Internal medicine (18 th

edition); page number:1632.http://www.authorstream.com/Presentation/

airamsherlyn-1606284-dengue-hemorrhagic-fever/http://www.slideshare.net/orlandito12/dengue-fever-

power-point?next_slideshow=1