Unified Data for Actionable Biomarkers

What Is BiomarkerBase? • A manually curated database

that aggregates information from publicly available sources that describe the clinical use of biomarkers.

• Provides access to biomarkers that can’t be found through searches in public sources.

• Links biomarker information together by target, disease, drug, therapeutic area, and company.

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http://www.biomarkerbase.com

- IVD Tests cleared or approved by FDA since the end of 2002 that utilize one or more biomarkers.

- Drugs, all FDA-approved, that include a biomarker in the label.

- Clinical Trials, phase 3 and 4, initiated since the end of 2011, which include “marker” in the record. Phase 2 trials by Nov ‘13.

- Publications describing clinical studies that include biomarkers from the sources above.

Current Datasets

Biomarker Definition: A nucleic acid, peptide or hormone that is potentially useful

for diagnosis, prognosis, or companion diagnosis.

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Public sources of biomarker information lack

connectivity and have severe querying

limitations.

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Query limitation #1: Some of the most critical information can’t even be searched.

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Query limitation #1: Some of the most critical information can’t even be searched.

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Query limitation #2: Nomenclature isn’t standardized.

Search Term

Studies Returned

ca 125 153

ca-125 140

mucin-16 138

mucin 16 138

MUC16 0

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BiomarkerBase Difference

Manually Curated

Comprehensive

Clinically Focused

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Who Uses BiomarkerBase?

Diagnostic Companies Product development; business development; marketing

Drug Companies Clinical trial planning; partnering; test selection

Life Science Companies Product development; business development; marketing

Research Institutions Licensing

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Subscription Pricing

Single User • $1,000 / year

• Access for one individual

Multi User • $2,500 / year

• Unlimited users at a single site within one company or institution

• Multi-site licenses are also available at discounted pricing.

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Amplion Research Inc. 1011 SW Emkay Drive, Suite 200 Bend, Oregon 97702 USA support@amplion.com +1.503.389.1157

Contact Information

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