Post on 30-Nov-2014
description
Canadian Transplantation Highlights1956: Heart valve* transplants are performed in Toronto, Ontario.1958: First successful kidney transplant, between identical twins, is performed at the Royal Victoria Hospital in Montreal, Quebec.1963:First kidney transplant from a deceased donor is performed in Montreal, Quebec.1968:First heart transplant is performed in Montreal, Quebec.1970:First liver transplant is performed in Montreal, Quebec.1974:First pediatric bone marrow transplant is performed in Toronto, Ontario.1983:First heart-lung transplant is performed at the University Hospital in London, Ontario. Successful single lung* transplant is performed at the Toronto General Hospital in Ontario. 1986:Successful double lung* transplant is performed at the Toronto General Hospital in Ontario.1988:Successful liver-bowel* transplant is performed at the University Hospital in London, Ontario.1989:Islet cells are transplanted into a patient with diabetes at the University of Alberta Hospital in Edmonton.1993:First living-related (parent to child) partial liver transplant is performed in London, Ontario.1995:In Montreal, Quebec, pig liver tissue is used as a bridge to keep a patient alive until a human liver became available for transplant.1997:The London Health Sciences Centre in Ontario transplants a liver, bowel, stomach, and pancreas into a five-month-old infant – the world's youngest recipient of a multi-organ transplant.2000:First adult-to-adult living liver transplant is performed in London, Ontario.2004:First live kidney donor transplant from an anonymous donor to an unrelated recipient is performed in Vancouver, British Columbia.
*A world first
2015 Joint Meeting A Triumph of Canadian Innovation and Cooperation, Like 1983!
The Banff ProcessConsensus communication in renal transplantation
a
The Banff lesions g, i, t, v - score
The Banff communityPathologistsNephrologistsTx-SurgeonsLab-Medicine
The Banff communityPathologistsNephrologistsTx-SurgeonsLab-Medicine
established by
consensus in 1991
The Banff classificationCurrent consensus for diagnostics
The Banff classificationCurrent consensus for diagnostics
moderated
Banff meetingsthesis-antithesis-synthesis
tentative
thresholds
participate
refinementBanff Working Groups
Feedback concerning weaknesses and strengths by results from independent research
New membersBiostaticiansMolecular Biologists“Omics”-specialists
New membersBiostaticiansMolecular Biologists“Omics”-specialists
Off-springsLiverPancreasLung, HeartCTA
Off-springsLiverPancreasLung, HeartCTA
• 1991 First Conference• 1993 First Kidney International publication• 1995 Integration with CADI • 1997 Integration with CCTT classification• 1999 Second KI paper. Clinical practice guidelines. Implantation biopsies.• 2001 Classification of antibody-mediated rejection (ABMR): Regulatory agencies participating• 2003 Genomics focus, ptc cell accumulation scoring• 2005 Gene chip analysis. Elimination of CAN, identification of chronic antibody-mediated
rejection.• 2007 First meeting far from a town called “Banff” – La Coruna, Spain.• 2009 Working groups. Meeting in Banff, Alberta, Canada • 2013 Establishment of Banff Foundation for Allograft Pathology and recognition of C4d-
negative ABMR
BANFF Classification - Milestones
Significance of ‘Banff papers’• 4244 citations of the 9 Banff meeting reports• 790 Banff / Transplantation papers in PubMed• Banff 2003 meeting report (ABMR criteria) = most cited AJT paper• 3 Banff meeting reports are among the top 4 cited AJT articles
Dunbar’s Number of 150 People You Can Have Significant Empathetic Friendships With. Need to Maintain This
Intimate Feeling in A Larger Meeting of 600.
Steven Paraskevas, MD, PhDPresident CST
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CST is…
• THE multidisciplinary professional organization of Canada’s organ donation and transplantation community.
• An association comprising close to 700 members and associate members• A professional NFP with longstanding ties to international partner
organizations• A dynamic player in the OTDT landscape continually re-evaluating its
relationship with agencies its own members helped lobby to create• Now in its 35th year• A longstanding affiliate of the TTS
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Teaching, education and professional
development
Developing consensus, best practices and
expert opinion
Fostering research and knowledge creation
• CST meeting has grown to showcase research from across Canada and around the world• Joint symposia with other societies: AST, CSN, CSI• Webinar series with the Transplantation Society• 2013 CST successfully negotiated the designation of SOT as an Area of Focused Competence within the Royal College• CST sponsors multiple annual training awards• The CST ASM is the principal venue for networking among the SOT and HLA specialties• CST is represented in all major committees at CBS• Special interest groups of our membership have always held annual or semi-annual networking/priority setting
meetings during the ASM: Kidney, Liver, Pancreas/Islet, Lung, Heart, Pediatric, Pharmacy, Allied Health, HLA, Donation• Canadian National Transplant Research Program (CNTRP) holds group meeting at the ASM, as well as showcasing its
annual achievements
Joint Banff/CST Program Committee
Co-chairs: Dr. Alexandre Loupy and Dr. Prosanto
Chaudhury
2015 Banff/CST Meeting Organizing Corporation (“2015 MOC”) – Co-Directors: Dr. John Gill, Dr. Michael Mengel
Members: Anthony Jevnikar, David Rush, Denis Glotz, Kim Solez, Marcelo Cantarovich, Mark Haas, Steven Paraskevas
Joint Banff/CST Finance Committee
Joint Program Structure
Banff activies
Joint activities
CST activities
2015 CST / Banff meeting program
Day 1: Monday Day 2: Tuesday Day 3: Wednesday Day 4: Thursday Day 5: Friday Day 6: SaturdaySession Potential Banff-premeeting Plenary Session: Progress Report
Banff Working groupsJoint Pleanary session I: Joint Pleanary session II: Concurrent sessions: Banff
meeting summary and CST symposia
08:00 - 08:30 08:30 - 09:00 09:00 - 09:30 09:30 - 10:00
10:00 - 10:30 Coffee break Coffee break Coffee break Coffee break Coffee break Coffee break10:30 - 11:00 11:00 - 11:30 11:30 - 12:00 12:00 - 01:00 Working Lunch: Banff registration
openWorking Lunch: Working Lunch: CST registration
openWorking Lunch: Lunch: Banff adjourns Lunch:
Session Potential Banff-premeeting Concurrent Organ Sessions Concurrent sessions: Banff Organ sessions and CST Working groups
Concurrent sessions: Banff Organ sessions and CST symposia
01:00 - 01:30 01:30 - 02:00 02:00 - 02:30 02:30 - 03:00 03:00 - 03:30 Coffee break Coffee break Coffee break Coffee break Coffee break Coffee break 03:30 - 04:00
04:00 - 04:30 04:30 - 05:00 05:00 - 05:30 05:30 - 06:00 Events
6:30 Welcome Reception - Cocktails and snacks. Open bar
Case presentations from varioous organs with Wine Beer and Food
Joint Poster Session with reception CST Awards and Joint CST/Banff Gala Dinner
CST President's dinner
Target Audience for the 2015 joint CST/Banff meeting: total ~600 expected international delegates
• Basic Scientists• Pathologists• Immunogeneticists and HLA experts• Transplant Physicians: Internal Medicine, Surgery,
Infectious Diseases, Critical Care• Allied Health Care• Students, Trainees, Fellows