General pattern of cis-acting control elements that regulate gene expression in yeast and metazoans (a) Genes of multicellular organisms contain both.
Phenologs An example of using bioinformatics to find new genes for genetic traits BIO337 Systems Biology / Bioinformatics – Spring 2014 Edward Marcotte,
B I O T E C N O L O G I A
YEAST GENETICS AND MOLECULAR BIOLOGY
Whole Genome Duplications (Polyploidy) Made famous by S. Ohno, who suggested WGD can be a route to evolutionary innovation (focusing on neofunctionalization)
Fault Tolerance in Protein Interaction Networks: Stable Bipartite Subgraphs and Redundant Pathways Lenore Cowen Tufts University.
Microarrays Dr Peter Smooker, [email protected].
Regulatory Network (Part II) 11/05/07. Methods Linear –PCA (Raychaudhuri et al. 2000) –NIR (Gardner et al. 2003) Nonlinear –Bayesian network (Friedman.
Functional genomics and inferring regulatory pathways with gene expression data.
Genomes summary 1.>930 bacterial genomes sequenced. 2.Circular. Genes densely packed. 3.2-10 Mbases, 470 - 7,000 genes 4.Genomes of >200 eukaryotes (45.
Problems at the interface between statistics, biomathematics and bioinformatics Chris Glasbey Biomathematics & Statistics Scotland.
Epistasis Analysis Using Microarrays Chris Workman.