Structural genomics
Protein Fold recognition Morten Nielsen, Thomas Nordahl CBS, BioCentrum, DTU.
©CMBI 2005 Why align sequences? Lots of sequences with unknown structure and function. A few sequences with known structure and function If they align,
GeoFold: A mechanistic model to study the effect of topology on protein unfolding pathways and kinetics Vibin Ramakrishnan *, Saeed Salem ‡, Saipraveen.
©CMBI 2009 Alignment & Secondary Structure You have learned about: Data & databases Tools Amino Acids Protein Structure Today we will discuss: Aligning.
Protein structure prediction Computer-aided pharmaceutical design: Modeling receptor flexibility
Protein structure
Protein structure Predictive methods. Topics Covered Secondary structure prediction methods 3D fold prediction –Ab initio protein structure prediction.