De-novo Assembly Day 4. The Challenge Given many (millions or billions) of reads, produce a linear (or perhaps circular) genome Issues: – Coverage – Errors.
CS 394C March 19, 2012 Tandy Warnow. 2 DNA target sample SHEAR & SIZE End Reads / Mate Pairs 550bp 10,000bp Shotgun DNA Sequencing Not all sequencing.
CS 394C Oct 16, 2013
De-novo Assembly
CS 394C March 19, 2012