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DRUGS AFFECTING LIPID METABOLISM MODERATOR: DR.J.G.BUCH SIR INTRODUCTION Lipoproteins Dyslipidemia Hyperlipoprote inemia Decreased level of HDL Hypercholester olemia Hyperlitriglycer…
1. Biotransformation(Metabolism) of Drugs 2. A. General properties1. Biotransformation is a major mechanism for drug elimination;• Results of biotransformation: – Production…
7/27/2019 3837Biotransformation (Metabolism) of Drugs 1/31Biotransformation(Metabolism) of Drugs7/27/2019 3837Biotransformation (Metabolism) of Drugs 2/31A. General properties1.…
Annu. Rev. Pharmacol. Toxicol. 2001. 41:443–70 Copyright c 2001 by Annual Reviews. All rights reserved METABOLISM OF FLUORINE-CONTAINING DRUGS B Kevin Park, Neil R Kitteringham,…
1. Lipid metabolism and Hypolipidemic drugsDr Urmila M. Aswar, Sinhgad Institute of Pharmacy, Narhe, Pune -41 2. LIPIDS • Esters of fatty acids and alcohols. • Insoluble…
1. METABOLISM OF DRUGS TO TOXIC PRODUCTS & THE CLINICAL RELEVANCE OF DRUG METABOLISMDr AakifaJaved 2. Metabolism of drugs & other foreign chemicals may not always…
Biotransformation of drugs (Drug metabolism)(Drug metabolism) PharmDr. Pavol Ježko, PhD. Department of Pharmaceutical Chemistry Faculty of Pharmacy, Comenius University…
PowerPoint PresentationJ. Steven Leeder, PharmD, PhD Children’s Mercy Hospital Kansas City, MO Disclosures In the past 12 months, I have no relevant financial relationships
1 PHASE II DRUG METABOLISM Fall 2011 Philip C. Smith, Ph.D. Room 1309, Kerr Hall 919 962-0095 [email protected] Outline: i. References ii. Definitions iii. Common features…
Introduction to Drug Metabolism Reference Sources • The Pharmacological Basis of Therapeutics Goodman and Gilman (lot of info, not cheap) • Introduction to Drug Metabolism…
Drug Safety Considerations in Drug Development MEDCHPCEUT 527 - Advanced Drug Metabolism 2011 Thomas A. Baillie, PhD, DSc School of Pharmacy University of Washington 1 Outline…
1 Anti-cancer drugs that target metabolism, is dichloroacetate the new paradigm? Ioanna Papandreou, Tereza Goliasova, Nicholas C Denko Division of Radiation and Cancer Biology,…
Biotransformation of drugs (Drug metabolism)(Drug metabolism) PharmDr. Pavol Ježko, PhD. Department of Pharmaceutical Chemistry Faculty of Pharmacy, Comenius University…
Chapter 13. Drug Metabolism Introduction: the process of drugs in the body includes absorption, distribution, metabolism and elimination. Drug metabolism is also named “drug…
DMD#85647 1 Rhinacanthin-C mediated herb-drug interactions with drug transporters and Phase I drug metabolizing enzymes. Wilasinee Dunkoksung, Nontima Vardhanabhuti, Pongpun…
Slide 1 Slide 2 Drug metabolism and elimination Slide 3 Metabolism The metabolism of drugs and into more hydrophilic metabolites is essential for the elimination of these…
BI M M 11 8 Drug Metabolism • Most metabolic products are less pharmacologically active Important exceptions: • Where the metabolite is more active (Prodrugs, e.g. Erythromycin-succinate…
Training course: Pharmacotherapy in Older People Juan Tamargo, MD, PhD, FESC Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense, Madrid…
Slide 1PHARMACOKINETICS DR NARENDRA KUMAR Slide 2 Pharmacokinetics of drugs (ADME) Are studies of Absorption Distribution Metabolism Excretion of drugs Slide…
BIOCHEMISTRY GENERAL MEDICINE METABOLISM OF FOREIGN COMPOUNDS RNDr Zdeněk DVOŘÁK PhD Department of Medical Chemistry and Biochemistry Faculty of Medicine Palacky University…