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1 Mosul University College of pharmacy Lec 9 Biopharmaceutics Hepatic Elimination of Drugs The elimination of most drugs from the body involves the processes of both metabolism…
BIOTRANSFORMATION OF DRUGS PHASE I: OXIDATION Submitted by:STEFFI K. BABU 1st MPHARM (PHARMACEUTICS) JSSCP, OOTY PHASE I BIOTRANSFORMATION Conversion of drugs from one chemical…
Drug metabolism, prodrug biotransformation
1. Biotransformation(Metabolism) of Drugs 2. A. General properties1. Biotransformation is a major mechanism for drug elimination;• Results of biotransformation: – Production…
1.FACTORS AFFECTING BIOTRANSFORMATION OF DRUGS PRESENTED BY: HADIA ARSHAD 2. TYPES OF FACTORS • Chemical • Biological • Altered Physiological • Temporal • Route…
8/13/2019 Lesson 3 Jezko Biotransformation of Drugs 1/48Biotransformation of drugsPharmDr. Pavol JekoCenter of Excellence PharmacyDepartment of Medicinal ChemistryCADD LaboratoryFaculty…
Phase I reactions Phase II reacions The effect of biotransformation on the biological activity of drugs: How the biological (pharmacological and toxic) activity of the metabolite
Biotransformation of the Analgesic-Antipyretic Drugs Metamizole and Aminopyrine by Genetically Polymorphic Enzymes Von der Fakultät für Lebenswissenschaften der Technischen…
Slide 1 Biotransformation of Drugs September 10, 2007 Frank F. Vincenzi Slide 2 Learning objectives: drug biotransformation Xenobiotic, endoplasmic reticulum & microsomes…
Toxikologie für Chemiker: Arten der Einwirkung von Chemikalien 1 • Aufgaben der Toxikologie • Kontakte mit Stoffen • Arten der Einwirkung von Chemikalien • Einteilung…
BIOTRANSFORMATION AND METABOLISM BIOTRANSFORMATION: Drugs being metabolized by enzymes and chemical reactions in the body before they are eliminated. Altered drug is known…
Excretion of drugs and kinetics of elimination Dr. Sanooz Raheem Objectives: Enumerate various routes of drug excretion List the types of renal excretion and their consequences…
Biotransformation of drugs (Drug metabolism)(Drug metabolism) PharmDr. Pavol Ježko, PhD. Department of Pharmaceutical Chemistry Faculty of Pharmacy, Comenius University…
Slide 1 EXCRETION renal excretion, drugs affecting elimination of other drugs, blood concentration levels I. FACTORS AFFECTING DRUG ABSORPTION DISTRIBUTION plasma-protein…
Biotransformation of drugs (Drug metabolism)(Drug metabolism) PharmDr. Pavol Ježko, PhD. Department of Pharmaceutical Chemistry Faculty of Pharmacy, Comenius University…
NST110: Advanced Toxicology Lecture 4: Phase I Metabolism Absorption, Distribution, Metabolism and Excretion (ADME): NST110, Toxicology Department of Nutritional Sciences…
Slide 1Chapter 15 Slide 2 Elimination of waste products Nitrogenous wastes Toxins Drugs Slide 3 Regulate aspects of homeostasis Water balance …
NST110: Advanced Toxicology Lecture 4: Phase I Metabolism Absorption, Distribution, Metabolism and Excretion (ADME): NST110, Toxicology Department of Nutritional Sciences…
Hughes-EnvTox.pdf
Slide 1SITES DRUG BIOTRANSFORMATION of HEPATIC METABOLISM undergo List of DRUGS Absorption Site Intestine & Colon Process Reductive Reaction SULFASALAZINE Slide 2 SITES…