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Francesco Regoli Detoxification and biotransformation of xenobiotics in marine organisms Department of Life and Environmental Sciences Polytechnic University of Marche-Ancona…
Biotransformation of Xenobiotics Biotransformation of Xenobiotics Overview Phase I and Phase II enzymes Reaction mechanisms, substrates Enzyme inhibitors and inducers Genetic…
Biotransformation of Xenobiotics Biotransformation of Xenobiotics Overview Phase I and Phase II enzymes Reaction mechanisms, substrates Enzyme inhibitors and inducers Genetic…
1. diaConjugation of salicylic acid 16.bin morphin steroids Dubin Johnson syndr. Ways of conjugation Sulfation – PAPS - sulfotransferases Sulfation – PAPS –
OP-NARE131246 1113..1117Robert Preissner and Saskia Preissner* Structural Bioinformatics Group, Institute for Physiology & ECRC, Charite – Universitatsmedizin Berlin,
1. • Detoxification pathways and waste disposal pathways are metabolic pathways devoted to removing toxins that can be present in our diets or in the air we breathe, introduced…
Basic Principles of Pharmacology Dr L Keshvara wwwedukeshcom ©EDUKESH LLC 2014 All Rights Reserved Biotransformation: Phase I and Phase II Metabolism • Xenobiotics: Xenobiotics…
Slide 1BIOTRANSFORMATION, Drug metabolism, detoxification Phase 2 conjugation Slide 2 su sulfation Glucuronidation (80%) Conjugation with amino acids glycosylation acetylation…
Functional Medicine University’s Functional Diagnostic Medicine Training Program Module 6 * FMDT 551A The Physiology and Biochemistry of Biotransformation/Detoxification…
Biotransformation of xenobiotics Biochemistry II Lecture 5 2009 (J.S.) After chemical modification, the more hydrophilic compounds are excreted into the urine, bile, sweat.…
PHASE II BIOTRANSFORMATION OF XENOBIOTICS IN POLAR BEAR Ursus maritimus AND CHANNEL CATFISH Ictalurus punctatus By JAMES C SACCO A DISSERTATION PRESENTED TO THE GRADUATE…
Biotransformation of xenobioticsBiotransformation of xenobiotics Biochemistry II Lecture 5 2008 JS Xenobiotics are compounds present in the environment thatXenobiotics are…
Metabolism of xenobiotics FM 3.5-10 CHE 5-6 Metabolism of xenobiotics Also called: ! Biotransformation, or detoxification Primary metabolism – secondary metabolism Goal:…
The Detoxification System Part II: Hepatic Biotransformation by Mark J Donohue Introduction By the early 21st century our society has increasingly been exposed to more and…
Metabolic Transformations of Xenobiotics Introduction of Biotransformation reactions Amin M. Kamel, Ph.D. Pfizer Global Research and Development Groton Laboratories Bioanalytical…
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Gut Cleanse…
1 Metabolism of Xenobiotics Suggested Reading: • Hodgson E, Goldstein J.A. Metabolism of Toxicants Phase I Reactions and Pharmacogenetics. In: Hodgson E , Smart R.C. INTRODUCTION…
21 Insecticide Resistance Sakine Ugurlu Karaağaç Plant Protection Central Research Institute Gayret Mah FSM Bulvari Yenimahalle Ankara Turkey 1 Introduction Insecticide…
Toxicology 3. toxicokinetics Biotransformation: Hepatic-first pass metabolism Xenobiotics absorbed from the gastrointestinal tract Exceptions: Mouth (Nitroglycerine, weak…
Detoxification Mechanisms in Fish -Regulation and Function of Biotransformation and Efflux in Fish Exposed to Pharmaceuticals and Other Pollutants Britt Wassmur Akademisk…