Patents for Digestive Disorders
Yuxing Liu Ph.D
Academy of Oriental Medicine at Austin
General Introduction• Digestive DisordersThe involved Zang-fu organs are mainly the Spleen and Stomach
ShangHanLun: Yangming & Taiyin Xiao+HuaST Xiao=take & rote foods---transport to SI------tubid----LI
Excess/Heat syndromeSP Intestine absorbs nutrients ------ transform & transport them
to other Zang organs Def./Cold syndrome
The Common Etiology
Basic Pathology
Clinical manifestations
Patents for SP Qi/yang Deficiency
• Shen Ling Bai Zhu Wan / Ginseng, Poria, & Atractylodes Pill
• Bu Zhong Yi Qi Wan / Great Tonify the Middle Pill
• Si Jun Zi Wan / “Four Gentlemen Pills”
• Fu Zi Li Zhong Wan:“Aconite Benefit-the- Center Pills”
• Shen Ling Bai Zhu Wan Ginseng, Poria, & Atractylodes Pill
Ingredients (classic formula)
Dang shen; Fu ling; Bai zhu; Gan cao. Shan yao; Chen pi; Sha ren; Bai bian dou;Yi yi ren. Jie geng; Lian zi rou
• Bu Zhong Yi Qi Wan Great Tonify the Middle Pill
Ingredients (classic formula)Huang Qi; Dang shen; Gan cao; Bai zhu.
Dang gui; Chen pi; Sheng ma; Chai hu; Sheng jiang; Da zao
Si Jun Zi Wan / “Four Gentlemen Pills”
Functions• Tonifies SP qi & Dispels dampClinical Applications1. Deficiency of qi causing fatigue, weak voice, poor appetite,
loose stool, and weak limbs.2. Chronic gastritis and digestive disorders including ulcer.3. Used adjunctively as a SP qi tonic for chronic weak cough,
difficulty breathing4. Recovery from childbirth or chronic illness.5. Others
Brand, Packaging & DosagePlum flower brand; bottles of 200 pills, 8TID (can be increased to 12
pills as needed)
IngredientsDang shen Codonopsis; Chao Bai zhu Atractylodes; Fu ling Poria; Gan cao Licorice
Fu Zi Li Zhong Wan / “Aconite Benefit-the-Center Pills”
Ingredients Fu zi; Gan jiang; Bai zhu; Dang shen; Gan caoFunctions· Warm the MJ, Dispel Internal cold; · Nourish SP/ST Qi *Very warming Rx!Clinical Applications1. REPRESENTATIVE RX FOR SHAO YIN STAGE2. Spleen Yang Xu: digestive - Warm the InteriorUse for SP Qi and Yang Xu – Sx: vomiting, poor digestion, loose stools or diarrhea,
abdominal pain/cold cramping, clear urine, cold limbs; P: deep, thin; T: w/o much coating
In acute cases – vomiting, explosive diarrhea, and abdominal pain
Chronic digestive dysfunction, ulcerative colitis, acute gastroenteritis, gastric ulcer.
Packaging & Dosage Plum Flower Brand. D: 8-12 pills TIDPrecaution: Once the condition has improved, reevaluate the need to take this – very warming Rx- Do not use w/ signs of Heat! - PREGNANCY
Patents for Spleen-Stomach disorders
Stomach/Intestine disorders
Xiang Sha Liu Jun Zi wan “Saussurea & Amomum 6 Gentlemen Pills”
IngredientsMu xiang Saussurea; Sha ren Amomum;
Dang shen Codonopsis; Bai zhu Atractylodes; Fu ling Poria; Gan cao Licorice; Chen pi Orange peel; Ban
xia Pinellia; Sheng jiang Fr ginger; Da zao Jujube
Functions• Strengthen SP/ST; Tonify & Move Qi• Eliminate Dampness retention and phlegm • Stop pain (ST)
Clinical ApplicationsSP/ST Qi Xu w/ D-C stagnating in the MJ
– Sx: poor digestion w/ n, v, burping, regurgitation, ST gurgling, borborygmus, abdominal distension, stomach ache, chronic diarrhea,
pale face; T: pale; P: slow, weakWestern dz: Gastric or duodenal ulcer, acute/chronic
gastritis, chronic diarrhea, Crohn’s dz* ST Xu, SP Qi Xu, SI Qi pain from XU, LI Xu Cold
PrecautionsAvoid raw and cold foods
Packaging & Dosage12 pills,TID, before meals- more effective if cold and raw foods are avoided
BrandLanzhou Tanglong Min-kang
Zi Sheng Wan / “provide life pills”
Functions• Tonifies SP qi; • Dispels food stasis• Harmonizes ST• Counters ascent of ST qi• Dispels damp and clears summer heat
IngredientsDang shen; bai zhu; fu ling; gan cao. shen qu; mai ya; shan zha; shan yao; bai bian dou; lian zi; yi yi ren; ju hong; jie geng; qian shi; huo xiang; ze xie; bai dou kou; huang lian
Clinical Applications1. Chronic digestive complaints characterized by
accumulation of food matter and damp. Symptoms include poor appetite, abdominal distention, nausea, and loose or erratic stools.
2. Acute summer damp heat syndromes or food poisoning characterized by vomiting or diarrhea.
Brands, Packaging & DosageMinshan brand: Bottle of 200 pills, 8 – 12 pills Bid.Tanglong: 10 – 12 pills TID
Curin(g) Wan / Kang Ning Wan / “Healthy Peaceful Pill”
See Patents for Summer heat
(Ren shen) Jian Pi Wan “(Ginseng) Strengthen the Spleen Pill”
Functions• Strengthen SP, Eliminate
Dampness• Regulate ST/SP Qi, Move food
mass
IngredientsDang shen Codonopsis; Bai zhu Atractylodis; Shan zha Hawthorne; Mai ya Sprouted barleyZhi shi Immature citrus; Chen pi Orange peel;
Clinical ApplicationsTx chronic SP Xu w/ accumulation of food matter– SP/ST Sx: stuck food, poor appetite or digestion, distention in the
epigastrium or abdomen, borborygmus,nausea,fatigue, pale face, poorly formed stools; P: weaker
-- Intestinal Sx: diarrhea or loose stools d/t Dampness associated w/ SP Qi Xu
PrecautionsDo not use w/ nursing women (d/t mai ya)
Packaging & Dosage8 pills,TID after meals
BrandsLanzhou Minshan Tanglong Bio Essence Tientsin Drug Manufactory: Ren shen;Bai zhu;Shan zha;Yi yi ren;Mu xiangZhi shi; Dang gui;Sha renClassical from Bensky p 458:Ren shen; Chao bai zhu; Fu ling; Gan cao.Shan
zha; Chao mai ya; Chao shen qu; Chen pi; Shan yao. Rou dou kou; Sha ren; Mu xiang;Jiu chao huang lian;
Xiang Sha Yang Wei Wan / “Aucklandia, Amomum nourish ST pill”
Functions• Dispel damp, transform phlegm, • harmonize ST, counters ascent of ST qi, stops
vomiting• Soothes LIV• Promote digestion
Ingredients (minshan)Mu xiang; Sha ren. Bai zhu, Fu ling, Gan cao; Chen pi; Ban xia; Hou po; zhi shi; sheng jiang; Bai dou kou; Huo xiang; Xiang fu; da zao.
Herbal times; Tanglong brand: Sheng jiang gan jiangLanzhou Foci: take out sheng jiang; da zao
Clinical Applications1) chronic digestive complaints: Sx: reduced appetite, abdominal
distension, accumulation of phlegm and food matter, nausea, acid regurgitation, borborygmus and loose or erratic stool.
2) Western dz: acute or chronic gastritis, gastric or duodenal ulcer, chronic hepatitis
PrecautionsCaution for PREGNANCY
Packaging & DosageBottles of 200 pills, 8-12 TID
BrandsMinshan; Herbal Times; Tanglong; Lanzhou Foci
Bao He Wan / “preserve harmony pills”
Ingredients (classic formula) Shan zha; shen qu; lai fu zi; mai ya. Ban xia; fu ling; chen pi. lian qiao.Functions• Dispels foods stasis; • Harmonize ST, stems counterflow ascent of ST qi• Clears heat, dispels damp• Tonifies SP qi, promotes digestionClinical Applications1. acute or chronic food stagnation, with symptoms of indigestion, epigastric or abdominal
bloating or distention, belching, hiccoughs, nausea, poor appetite, or poorly formed stools.
2. useful in morning sickness, motion sickness, overeating, and to alleviate hangover.3. also in infantile disorders due to food stagnation, including colic, poor appetite
abdominal distension and nocturnal cough with abundant expectoration. Precautions caution during pregnancyPackaging & DosageBottle of 200 pills, 8-12 pills Tid. bio essence: 6-8-11 pills BID-TID; Herbal times: bottles of 100 pills, 5-8 pills TIDBrandsMinshan; Lanzhou Foci; Tanglong; bio essence; herbal times
Mu Xiang Shun Qi Wan “Saussurea/Aucklandia Regulate Qi Pills”
Functions• Moves stuck Qi in the MJ, Warms
the MJ, Stop pain• Strengthen ST, Disperse food mass• Dispels Damp• Harmonizes LIV & ST
IngredientsDang gui; hou po; mu xiang; bai dou kou; cang zhu; yi zhi ren; ze xie; qing pi; wu zhu yu; gan jiang; chen pi; fu ling; ban xia; sheng ma; chai hu
Tanglong brand has different ingredients
Clinical ApplicationsRegulate Qi: Food Yu LIV SP w/ poor diet 1) Digestive complaints d/t SP Yang Xu w/ accumulation of food and Damp – Sx:
indigestion, epigastric or abdominal distension, poor appetite, borborygmus, loose or erratic stools, sensitivity to cold foods
2) Indigestion d/t overeating or poor eating habits3) Slow moving digestion w/ Sx of bad breath or belching associated w/
hypoacidity and insufficient acid to digest foodWestern dz: Chronic Hepatitis, ascites, cirrhosis of the liver (early stage), chronic
gastritis, intestinal spasms (abdominal pain)
Precautions- Not for – PREGNANCY
Packaging & DosageBottles of 200 pills, 8-12 TID
BrandsMinshan; Lanzhou Foci Pharmaceutical factory;Lanchow Chinese medicine works
Sai Mei An
Functions• Decrease excess ST acid, Stop
bleeding• Protect mucosa lining of ST• Stop ST ache, Promote tissue
regeneration
IngredientsZhong ru shi Stalacitite; Han shui shi Calcite; Bing pian Borneol; Zhen zhu Fr pearl; Wa leng zi Cockle shell; Bai cao shuang Fuligo e herbisor; Fu long gan Terra flava usta; Hai ge ke Clam shell
Clinical ApplicationsClear Heat: ST hyperacid. & ulcer (Protect mucosa lining of ST& promote
tissue regeneration) 1) Acid regurgitation, heat, and pain; Stomach cancer2) Tx gastric or duodenal ulcer, or acute or chronic gastritis d/t hyperacidity in
the stomach3) Tx mouth ulcer or stomatitis – apply topically
Precautions- do not take in conjunction w/ any other ralkaline substances
Packaging & Dosage3 pills,TID, taken ½ hour before a meal (empty stomach)* Only use for short-term
BrandsSai Mei An Pharmaceutical Manufactory
Xiang Lian Wan “aucklandia, coptis pills”
Functions• Clears heat, resolves toxin• Transform damp• Descends qi downwards• Relieves dysentery• Relieves pain
IngredientsHuang lian 80%, mu xiang 20%
Clinical Applications1. acute heat toxin dysentery or gastroenteritis causing diarrhea
with mucous, pain and tenesmus.2. diarrhea and cramping due to food poisoning, protozoan
infection3. ST ulcer. .
Packaging & DosageBottle of 200 pills, 8-12 pills Tid.
BrandsPlum flower
Patents for Promoting Bowel Movement
Run Chang Wan / “Moisten the Intestine Pill”
Functions• Moisten the intestines, frees the stool, clears and
purges the bowel• Clears heat• Tonifies (moves) blood
minshan Lanzhou Foci TanglongTao renHei zhi maDang guiDa huangQiang huo
Tao renHuo ma renDang guiDa huangQiang huo
Tao renHei zhi maDang gui weiDa huangQiang huo
Ingredients
Clinical Applications1. Chronic constipation due to heat, deficiency of
fluid and deficiency of blood2. helpful in chronic constipation due to older
age, weakness, postpartum or during a fever.
Precautions prohibited during pregnancy; reduce dosage or discontinue if diarrhea develops.
Packaging & Dosage Bottle of 200 pills, 4 - 8 pills Tid. (Tanglong 8-12 TID)
Brands
Tao Ren Wan/ “persica pills”
Functions• Moisten the intestines, frees the stool, clears and
purges the bowel• Clears heat• Tonifies (moves) blood
IngredientsHuo ma ren; da huang. Tao ren; dang gui wei; qiang huo.
Clinical Applications1. Chronic constipation due to heat, deficiency of fluid and deficiency of blood2. Chronic constipation due to older age, weakness, postpartum or during a fever.
Precautions prohibited during pregnancy; reduce dosage or discontinue if diarrhea develops.
Packaging & Dosage Bottle of 200 pills, 8 pills Tid.
Brands plum flower
Ma Zi Ren Wan/ “cannabis seed pills”
Functions• Moistens the intestines• Movies qi• Clears heat• Frees the stool
Ingredients (classic formula)Huo ma ren; da huang; zhi shi; hou po; xing ren; bai shao.
Clinical Applications1. constipation due to dryness, heat, and Qi stagnation2. use in heat and excess conditions where the yin has been depleted, with
symptoms of dry hard stool, frequent urination, and dry mouth.3. helpful in constipation following illness, childbirth, or surgery. 4. also useful for hemorrhoid accompanying constipation, and abdominal
pain due to worms.
PrecautionsProhibited during pregnancy.
Packaging & DosageBottle of 200 pills, 8 – 12 pills Tid.
BrandsPlum flower; herbal times
Tong Bian Wan / “free the stool pills”IngredientsHe shou wu; yu li ren; qiang huo; tao ren; dang gui; da huangFunctions• Moisten the intestines, frees the stool, clears and purges the bowel• Tonifies bloodClinical Applications1. Chronic constipation due to deficiency of fluid and deficiency of
blood2. helpful in chronic constipation due to older age, weakness, postpartum
or during a fever. PrecautionsProhibited during pregnancy Packaging & DosageBottle of 200 pills, 6-8-11 pills BID-TID.BrandsBio essence
Tong Shun Wan / “free, smooth pills”
FunctionsMoisten the intestines, frees the stool, clears and purges the
bowel; Clears heat; Movies bloodClinical ApplicationsConstipation due to heat, deficiency of fluid/blood or blood
stasis
PrecautionsFan xie ye can lead to vomiting and abdominal pain if
overdosed. Prohibited during pregnancy; reduce dosage or discontinue if diarrhea develops.
Brands,Packaging & Dosageplum flower brand. Bottle of 100 pills, 2-3 pills BID-TID.
IngredientsFan xie ye; huo ma ren; da huang. tao ren; dang gui wei; qiang huo
Patents for Anal disorders
Huai Jiao Wan / “Sophora Fruit Pills”
Functions• Clear Heat in the LI• Stop bleeding d/t Wind in the LI, which
produces stool w/ fresh blood
IngredientsHuai jiao Sophora/pagoda fruit; Di yu SanguisorbaZhi Ke Citrus; Dang gui Angelica; Fang feng Ledebouriella; Huang qin Scutellaria
Clinical ApplicationsWind-Heat-type bleeding hemorrhoids or intestinal bleeding -- Clear Heat, Reduce Fire1) Stop intestinal bleeding from Heat where there is fresh blood w/ or w/o the
stool2) Intestinal bleeding associated w/ Excess Heat – Sx: burning sensation around
the anus, constipation or imcomplete sensation following bowel movement (D-H in LI), thirst; P: rapid
3) Stop bleeding from hemorrhoids (d/t heat): internal or external bleeding in the LI
PrecautionsPREGNANCY
Packaging & Dosage9- pills,TID
Brands;Min-kang Plum Flower
Ma Ying Long Zhi Chuang Gao
FunctionsClear away heat and toxic materials; Promote qi & blood Circulation, remove blood stasis; Promote wound healing Clinical ApplicationsInternal/external hemorrhoids; Anal fissure; perianal eczema.
Precautions.Not in pregnancyBrands; Packaging & DosageInfuse it appositly into anus, or apply it on affected area.
IngredientsShe xiang (Musk); Niu huang; Zhen zhu; Lou gan shi; Mei pian
(She Xiang) Xiong Dan Zhi Ling Gao “Musk & Bear GB Hemorrhoid Ointment”
Functions• Clear H, Detox; Reduce inflammation; Stop pain & bleeding
Clinical ApplicationsClear Heat, Reduce Fire – Hemorrhoids 1) Tx acute (~1 wk) presentation of hemorrhoids w/ inflammation and bleeding
– Sx: swelling, burning sensation, itching, constipation 2) Tx anal fissure
Precautions* External application only!
Brands ;Packaging & DosageChung-lien Drug Works Apply topically to clean area, 1-3 x day
IngredientsXiong dan Bear gb; Bing pian Borneol; Zhen zhu Fr pearl;Chi shi zhi Hallosite;She xiang
Qiang Li Hua Zhi Ling / Extra Strenth Fargelin “Extra Strength Transform Hemorrhoids Remedy”
Functions• Clear Heat, Stop pain and bleeding• Reduce inflammation Clinical ApplicationsSevere Hemorrhoids (general Sx) Clear Heat, Cool Xue1) Stronger than Hua Zhi Lin Wan for general hemorrhoids – more acute; yet not
as strong from bleeding d/t Heat than Huai Jiao Wan2) Tx internal and/or external hemorrhoids; prolapsed anus3) Stops bleeding, pain, and prevents infection Packaging & Dosage3-4 pills,BID ot TID BrandsUnited Pharmaceutical
IngredientsHu po Amber; Xiong dan Bear GB; San Qi Pseudoginseng; Huang qin Scutellaria; Yuan hu suo Corydalis; Di yu Sanguisorba;Huai hua Sophora jap.; Zi zhu cao Callicarpa
Wei Te Ling “204” “Stomach Special Effective-Remedy”
Functions• Strengthen ST; Relieve ST ache d/t stagnation; • Neutralize excess acid in the ST; Relieve pain Clinical ApplicationsRegulate Qi: ST hyperacid. & ulcer1) Tx stuck Qi in the SP/ST ST ache, heartburn, burping, acid reflux w/ pain (not too
much heat), sharp epigastric pain during eating,nausea,fullness, stools that resemble “coffee grounds” (which indicate bleeding in the ST)
2) Western dz: gastric or duodenal ulcer, gastritis w/ hyperacidity in the ST, ST distension and gas
Packaging & Dosage4-6 pills,TID, taken before a meal, or when necessary BrandsTsingtao Medicine Works
IngredientsWu zei gu / hai piao xiao Cuttlefish bone; Yuan hu suo Corydalis;Feng mi honey
707 Wei Yao / “Stomach Medicine”
Functions• Strengthen SP/ST• Neutralize Excess acid in the ST,
Reduce ST pain • Subdues Yang, Generates tissue
IngredientsYan hu suo Corydalis; Hai piao xiao/ Wu zei gu Cuttlefish bone; Qing mu xiang Aristolochia; Zhen zhu mu Mother of pearl; Ming fan Alum; Feng huang yi Honey comb; Jin nei jin Chicken gizzard
Clinical ApplicationsRegulate Qi:1) Excess ST acid causing epigastric ulcer w/o bleeding – Sx: sharp epigastric
pain during eating2) Tx stuck Qi in the ST ST pain; used to move stuck SP Qi, decrease
distension, reduce gas, stop pain, reduce burping and regurgitation of ST acid
3) Western dz: acute/chronic gastritis d/t only Excess ST acid will reduce and neutralize the ST acid
4) Gastric or duodenal ulcers will reduce acidity, stop pain and promo tissue regeneration in the ST mucosa and muscles
PrecautionsOD can diminish healthy digestive f(x)
Packaging & Dosage3 pills,BID or TID, taken before meals or when necessary
BrandsZhengjiang Chinese Medicine Works
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