Introduction to Bruker Optics,Introduction to Bruker Optics,NSC Mid Year Sales Meeting Sept 2007,NSC Mid Year Sales Meeting Sept 2007,
By Muhammad SaeedBy Muhammad Saeed
Bruker Optics
• offers the complete product line
• is leading in technology and innovations
• is steadily growing
• is the only European supplier
• is world wide present
FT-IR FT-NIR Raman Terahertz TD-NMR
Our products are based on
molecular spectroscopy
Founded in 1960 in Germany
Bruker world wide today :
> 3000 Employees
> 25 Locations
> 50 Sales and Service Offices
> 700 Mio. $ Revenue
Bruker Group
Bruker Group
X - Ray Fluorescence and Diffraction
Mass Spectrometry
NMR-Spectrometry
Optical Spectroscopy
Company Technology
Process Monitoring Laboratory Analysis Research & Development
Bruker Optics - we offer solutions
Life Science Academics Quality Control
Bruker Optics product line
Bruker is the only supplier with a complete product line
TENSOR 27/37FT-IR
Spectrometer
VERTEX 70/80FT-IR
Spectrometer
IFS 125FT-IR
Spectrometer
1.) Basic IR up to highest resolution spectrometer.
World record: The IFS 125 HR is the spectrometer with the highest resolution in the marketWorld record: The Alpha is world’s smallest FTIR Spectrometer.
ALPHAFT-IR
Spectrometer
Bruker Optics product line
2.) Microscopy
-Sample compartment microscope
-IR microscope
ImagingHYPERIONHELIOS
-IR imaging microscope
-Raman microscope
Bruker is the only supplier with a complete product line
Bruker Optics product line
3.) Near IR spectrometer
-Lab QA/QC
-Process
MPA MATRIX Industry
Bruker is the only supplier with a complete product line
Bruker Optics product line
4.) Complete Raman product line
FT-Raman module
FT-Raman spectrometer
Dispersive Raman process
Dispersive Raman microscope
Bruker is the only supplier with a complete product line
RAM II RFS 100 SENTINEL
Bruker Optics product line
5.) Plus
Minispec
TeraHertz
Spectrographs
Bruker is the only supplier with a complete product line
minispec TeraView Spectrographs
Bruker Optics product line
Bruker is the only supplier with a complete product line
6.) Solutions for dedicated markets:
- Process
PAT Food Polymer
Bruker Optics product line
Bruker is the only supplier with a complete product line
6.) Solutions for dedicated markets:
- Life Science
Proteomics Microbiology Tissue
Bruker OpticsIntroduction to FT-IR spectroscopyIntroduction to FT-IR spectroscopyIntroduction to FT-IR spectroscopyIntroduction to FT-IR spectroscopy
Bruker Optics
In the year 1800 the astronomer Friedrich Wilhelm Herschel analyzed the spectrum of sunlight. Herschel created the spectrum by directing sunlight through a glass prism so that the light was divided into its different colors. He measured the heating ability of each color using thermometers with blackened bulbs. When he measured the temperature just beyond the red part of the spectrum he noticed some kind of invisible radiation. Much to his surprise he found that the area close to the red part (i.e. an area apparently devoid of sunlight) had the highest heating ability of all. Herschel concluded that there must be a different kind of light beyond the red portion of the spectrum, which is not visible to the human eye. This kind of light became known as “infrared” (below red) light.
Herschel then placed a water-filled container between the prism and thermometer and observed that the temperature measured was lower than the one measured without the water. Consequently, the water must partially absorb the radiation. In addition, Herschel could prove that depending on how the prism was rotated (i.e. depending on the spectral range) the difference in the temperatures measured for each color varied. This was the beginning of infrared spectroscopy.
Infrared spectroscopy measures the infrared light that is absorbed by a substance. This absorption depends on the wavelength of the light.
Friedrich Wilhelm Herschel(1738 - 1822)
Discovery of infrared light
Visible light and infrared light are two types of electromagnetic radiation, but with different wavelengths, or frequencies. In general, electromagnetic radiation is defined by the wavelength or the linear frequency . The wavelength is the distance between two maxima on a sinusoidal wave.
The frequency is the number of wavelengths per unit time. Since all electromagnetic waves travel at the speed of light, the frequency corresponding to a given wavelength can be calculated as:
= c/
According to the Plank’s Radiation Law, the frequency of electromagnetic radiation is proportional to its energy.
E = h•
In infrared spectroscopy wavenumber is used to describe the electromagnetic radiation. Wavenumber is the number of wavelengths per unit distance. For a wavelength in microns, the wavenumber, , in cm-1, is given by
= 10000/
The electromagnetic spectrum
Sinusoidal wave of wavelength ~
~
The electromagnetic spectrum
The electromagnetic spectrum
The electromagnetic spectrum
The electromagnetic spectrum
Interaction of radiation and matterIf matter is exposed to electromagnetic radiation, e.g. infrared light, the radiation can be absorbed, transmitted, reflected, scattered or undergo photoluminescence. Photoluminescence is a term used to designate a number of effects, including fluorescence, phosphorescence, and Raman scattering.
Incident light beam Incident light beam
Reflection
Matter
Photoluminescence
Scattering
TransmissionAbsorptionAbsorption
Interaction of radiation and matter
15,000 cm-1 4,000 cm-1 400 cm-1 5 cm-1
NIRNIR MIRMIR FIRFIR
Separation of spectral ranges
Infrared light emitted from a source (e.g. a SiC glower) is directed into an interferometer, which modulates the light. After the interferometer the light passes through the sample compartment (and also the sample) and is then focused onto the detector. The signal measured by the detector is called the interferogram.
General FT-IR spectrometer layout
The working principle of an FT-IR spectrometer
FT-NIR Spectrometer
MPA - Multi Purpose Analyzer
MATRIX-I: Process Analysis in Diffuse Reflection
FT-NIR Spectrometer
Qualification of Raw Materials
• Disinfecting Materials
• Detergents
• Aromas
• Milk Powder (liquid Milk)
• Thickening Agents
• Starches
• ....
NIR Spectroscopy in the Food Industry
• Sugar Content in Water/juices
• Pure Yolk/Alcohol Content in Egg Liquor
• Moisture Content/Total Sugar in Marzipan
• Fat/Protein/Water/Mineral Salt in Sausages
• Fat/Water/Protein/sugar in Mayonnaise or in Chocolate
• Fat/Dry Matter in Ice Cream
• Caffeine in Black Tea
• Caffeine in Instant Coffee
• Bloom-Number in Gelatine
• Trans Fatty Acids in Edible Oils (MIR)
• Moisture/Protein/Starch/Ash/Raw Fiber in Cereals
• Moisture/Nicotine in Tobacco
• ....
Quantification of Ingredients
NIR Spectroscopy in the Food Industry
• Additives (Antioxidants, Lubricants, Modifiers, ...)
• Filler• physical Properties
(Density, Viscosity, ...)• averaged Molecular Weight• MFI (Melt Flow Index) • Humidity• Content of Carboxyl End Groups• OH-Number• Acid Number• Monomer Content...
Applications
NIR IN Polymer Chemistry
• Stabilizer Content• Content of Rest Monomer• Density• Viscosity• MIBK (Methyl-Isobutyl-Ketone)• WPE (Weight per Epoxy)• MBCI (Poly(Etherurethane)Diisocyanate)• Content of Total PE, PEP, PEEP and
Block-Co-Polymer
...
NIR in Polymer Chemistry
• Octane Number (RON & MON)
• Flash Point
• Cloud Point
• Boiling Behavior
• Cooling Behavior
• Content of Aromates
...
NIR Applications In Petrochemistry
NIR Applications of Pharmaceuticals
• Identification in the Receipt of Goods• Quantification of
– active Materials– auxiliary Materials– Filler
in Powders, Capsules, Tablets or Phials• Water Content in Powders• Surveillance of Drying Processes• Mixing• Solvent Recovery• Placebo/Verum Studies• Wall Thickness of Capsules• physical Properties (Hardness,
Brittleness, … )
NIR Application in Feed and Feed ingredients
The Feed and Feed Ingredients calibrations include feed for various animals like ruminant, poultry, swine, horse and fish, as well as feed ingredients like seeds, cereals, legumes, roughage and animal by-products.
Feed and Feed Ingredients
Min % Max % R n Origin2
Moisture 2.1 21,6 0,952 36.000+ UK & Ireland, EU, USA,
Oil 0.1 61.6 0.998 27.000+ Australia, SE Asia,
Protein 1.7 61.7 0.994 39.000+ Pakistan, India, China,
Fiber 0.1 36.5 0.974 15.000+ J apan, Malaysia,
Ash 0.7 59.4 0.962 22.000+ Peru, Argentina, Brazil
Starch 0.1 77.5 0.988 6.000+
• Fast (10 - 20 sec. typical)
• No sample preparation, simple to operate
• No waste, no pollution
• Simultaneous determination of multiple
components per measurement
• Highly precise and accurate
• Measure through packaging
• Transferable methods
• Real time monitoring for process
Advantages
NIR
NIR
NIR (MPA) Advantages
Summary
• Very often the time consumption for the method development is for HPLC and GC higher than NIR
• The NIR analysis time is generally much faster.
• Mostly installation and maintenance-costs for in-line- & off-line application is much lower for NIR.
• NIR = cost effective!
Competition
Bruker Optics
Competition
FOSS = giant
Founded in 1956, >50 years exper.
1100 employees for Agri applications worldwide, 300 service & appl. staff
Present in 21 countries
Perfect marketing and market knowledge
100++ distributors
Created “agri” standards
Competition
FOSS:
6500/5000 will die in 2007
Still problems with InfraXact
Old fashioned XDS is promoted:
„XDS is the latest & outstanding technology. In the past only the high priced Pharma customers have had access. Now it is available for everybody.“
FOSS is getting more aggressive also in pricing
FOSS is in trouble – use it now!
Bruker Optics
Competition
THERMO:
Currently very active!
Focus on Pharma/PAT
Attacks classical BRUKER markets (non-agri)
Still relatively weak in NIR, but THERMO is a “sleeping shark”
Competition
THERMO Strategy:
Offering full options at low price
Engineering is weak
Our answer:
You need to know our USPs adapted to the customers needs
Demonstrate the value of MPA for the dedicated customer application
NIR: Quality beats price!
Competition
BÜCHI:
Focus on Agri and Grain
Cross selling
Active in limited number of countries (now
+US)
ABB:
Focus on Process and Dairy
Strong in Petro & all kind of OEMs
Strategy for the Key Markets
Strategy for Chemistry Applications
• Endless number of applications are possible: OH, acid number, QA/QC, in-line & off-line
• High benefits of NIR by replacing HPLC
• MPA = blockbuster
• Our sales structure fits perfectly to this market (solving applications on site)
• Bio fuels are coming!
Strategy for Polymer Applications
•Most Key Accounts are still OPEN like SABIC.
•Biggest margins could be earn by developing applications.
Strategy for Pharma Applications
• All world’s biggest companies are using Bruker’s MPA.
• Pharma could be best future prospective.
• Applications:
STILL: raw ID & tablet testing (by MPA)
Strategy for PetroChemistry Applications
•Saudi ARAMCO could be big customer and we can make good margin.
•Need to work very closly.
•NSC already involved and have done applications.
Strategy for F & F (Food & Agri) Applications
•The market still OPEN.
•Big Companies(Provimi,
Degussa, Addiseo, Nestlé, …) now
using Bruker’s systems which
could be useful for F&F business
in KSA.
•The Dairy Companies still using
old techniques which is good
news for us.
•Markets are ready for us. We are
highly welcome!!
To Do List
Bruker = Market Leader
We create the standards
(in non-agri)
Others will copy our success:
Save your market shares
Diversify – put not all eggs in one basket
To Do List
Put more efforts in the chemical market
Promote INGOT
Communicate (via M.Saeed) – Knowledge & expertise is getting more and more important
Do not hesitate to ask for support
One final remark about the future SM
www.brukeroptics.com
Thank you very much!
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