©2011 Waters Corporation 1
Empower 3Control of Instruments
3rd Party Control
Mogens Hallas
Nordic User Training 2011
Långvik, September 6th to 9th
©2011 Waters Corporation 2
©2011 Waters Corporation 3
Empower 3Obsoleted support of detectors
The following instrumentation is reaching its end of life, is on limited support status and will nolonger be supported in Empower 3:
- 410 RI Detector- 486 TUV Detector- 996 PDA Detector- 474 Fluorescence Detector
Support for the A5890S and 7673S under serial control (Using LAN Serial Control)But not serial busLAC/E control, will remain in Empower 3.
©2011 Waters Corporation 4
Equinox Serial 8-Port Card
Equinox Serial Card is only supported on Windows XP 32-bit – Not in Windows 7.
Current serial instrument support using the Equinox 8-port card is:- Agilent 5890 GC (5890S)- Agilent 7673 GC autosampler (7673S)- Agilent 6890 GC (all models, including 6890N)- Agilent 6850 GC (serial number <=US00003200)- Agilent 7694 Headspace Sampler- Waters busSAT/IN module- Waters 474 fluorescence detector- Agilent A1100 LC modules (not A1200 modules)
A new LAN based serial device is replacing the Equinox Serial Card
©2011 Waters Corporation 5
Prior to Empower 3Previously discontinued instrumenys
As a reminder, support for the following instruments has been previously been discontinued:
Not supported as of Empower 2- Integrity TMD- ISA BusLAC/E card- GPC 2000- 5890 GC (under busLAC/E control)- 7673 (under busLAC/E control)
Not supported as of Empower build 1154- 700, 710, and 712 Injectors- 715 Autosampler- LC Module 1
Not supported as of Millennium32 v4.0- Waters 490 Variable UV
©2011 Waters Corporation 6
Instrument Control
Provide a comprehensive, reliable and robust feature set for
each instrument we support.
— Waters works closely with its customers to ensure the
instruments supported with Empower Software provided scientist
the capabilities to realize the most value from their instrument
investment.
Instrument Driver Approach - Open Instrument Portal (OIP)— Similar to the Microsoft Printer driver approach
— Allows creation of software plug-ins to add hardware control capabilities
— Waters uses and other instrument vendors to create instrument control
©2011 Waters Corporation 7
What is OIP Technology?
Open Interface Portal (OIP) technology is a
software architecture that allows for a
standardized specification of the interaction
between the Data System and an instrument.
This allows for the development of an instrument
―driver‖ that can be added to Empower Software
without changing the core application.
OIP technology is separate from the physical
connectivity (serial, ethernet, USB, IEEE-488)
OIP technology takes advantage of other software
specifications: COM, ActiveX, XML
©2011 Waters Corporation 8
Extended Instrument Control Using OIP with Empower Software
One software solution for all chromatographic systems
— Reduced training, validation and support
16 vendors with over 235+ instruments
— Instrument control available from major LC Vendors including Waters, Agilent, Shimadzu, Hitachi and Dionex *)
— Instrument Control Available from major GC Vendors including Agilent, Shimadzu, PerkinElmer and Varian
New instrument control
— Waters ACQUITY H-Class
— Waters Thar SFC
— Beckman CE
— WFC III
*) some are still in testing
©2011 Waters Corporation 9
Created by Waters
— HPLC systems and module, ACQUITY UPLC™, Single-quad & Triple-quad
MS, A/D Converter, Agilent 6850 GC, Agilent 7694 Headspace Sampler,
Agilent 1100, 1200 and 1260/1290 series LC modules
Created by Other Instrument Vendors
— CTC PAL Autosamplers
— Varian 3900 GC
— Perkin-Elmer GC
— Tekmar HT3 Headspace Sampler
— Dissolution Baths
o Hanson SR8-Plus, Distek (2100C,
Evolution 6100 & 6300), Sotax and
Erweka DT800 Online System
— Selerity Polaratherm 9000
— Shimadzu Prominence LC 20 System
— Hitachi LaChrom Elite Systems
— Dionex
Instrument control via OIP
©2011 Waters Corporation 10
Complete list of all controlled systems
©2011 Waters Corporation 11
Third Party Instrument Control in Empower 3
Waters policy is to notify their software partners when a new informatics software product is under development. The Empower 3 team has notified all of our partners about Empower 3 and has offered beta software for use in testing
/development of ICS software, for Empower 3.
To date not all vendors have requested Empower 3 beta or released software. We have recently reminded our partners that the release of Empower 3 software and we would like to offer our mutual support of their products. We will contact
our partners again.
Please refer users who are requesting third party instrument control to the appropriate vendors to request support of these instruments in Empower 3.
©2011 Waters Corporation 12
Consistent instrument interface assist in training new software users as new techniques such as Gas Chromatography (GC) or Ultra Performance Liquid Chromatography (UPLC) are introduce to the laboratory.
Instrument control
©2011 Waters Corporation 13
Instrument Control
Once instrument parameters are entered into the Empower software they can be completely managed by the software to ensure that these same parameters are used for all future analysis. — If changes are required, all instrument parameters are
completely documented in Empower's embedded relational database with complete audit trail including what changes were made, who made the changes, when the changes were made and why.
©2011 Waters Corporation 14
Waters HPLC’s
Full control of Waters binary and quaternary pumps.
Full control of Multiple wavelength, Photodiode array, Fluorescence, and RI detectors.
Full Control of sample compartment and column oven temperatures
Full control of autosamplers.
Full control of Waters single quad mass detectors.
©2011 Waters Corporation 15
Waters UPLC
Full control of Waters binary and quaternary pumps.
Full control of Multiple wavelength, Photodiode array, Fluorescence, and RI detectors.
Full Control of sample compartment and column oven temperatures
Full control of autosamplers.
Full control of Waters Mass Spec detectors.
©2011 Waters Corporation 16
Waters Mass Detectors
Data acquisition and instrument control of Mass Detectors.
Greater specificity of analysis.
Easily use MS and MS/MS in QC and Development lab environments.
1st Chromatography Software to offer Tandem control and data processing in a network or regulated environment
©2011 Waters Corporation 17
Mass Detection Waters SQD & TQD
Data acquisition and instrument control of Mass Detectors
Greater specificity of analysis
Easily use MS and MS/MS in QC and Development lab environments
1st Chromatography Software
to offer Tandem control and
data processing in a network
or regulated environment.
©2011 Waters Corporation 18
Thar Method Station & SFC-MS Resolution Systems
— Analytical to semi-preparative purification solutions
Control includes:
— Fluid Delivery Module and co-solvent selection
— Photodiode Array, UV & ELSD detectors
— Column oven and column selection
— Automated Back Pressure Regulator
— Thar Autosampler
— Waters 3100 MS detectors
— Waters Fraction Collector III
Supercritical Fluid Chromatography (SFC)
©2011 Waters Corporation 19
ACQUITY UPSFC System
©2011 Waters Corporation 20
Dissolution Baths
Integrity of your HPLC
dissolution testing
methods and results,
helping increase lab
productivity.
Combined software and
hardware solution.
— Hanson SR8-Plus
— Distek 2100C, Evolution 6100
& 6300
— Sotax
— Erweka DT800 Online
Dissolution System
— Vankel VK 7000
— Vankel VK 7010
©2011 Waters Corporation 21
Agilent 1100/1200/1260/1290 LC
Full control of Isocratic,
Binary and Quatenary
pumps.
Full control of
Autosampler.
Full control of UV,
MWV, RI, FLD and DAD
detectors
Full control of column
oven.
©2011 Waters Corporation 22
Agilent 5890 Series II GC
Control with either 7673 or
G1512 Controller
Dual Tower capability (With
serial card only)
Detector Supported
FID,NPD,TCD,ECD
Sampling Rates of 1.25, 2.5,
5, 10, 20 points per second.
Fully Programmable
temperatures:
— limits, ramps, and hold
times.
Injector inlet zone
temperature setting.
©2011 Waters Corporation 23
Agilent 6890 / 6890N GC
6890 supported in both Single and Dual Tower mode.
Sampling Rates of 0.1, 0.2, 0.5, 1, 2, 5, 10, 20, 50, 100, and 200 points per second.
Fully Programmable temperatures:— limits, ramps, and hold times
Detector options:— Unknown (Other detectors)
— FID (Flame Ionization)
— TCD (Thermal Conductivity)
— NPD (Nitrogen Phosphorous)
— ECD (Electron Capture)
— uECD (Micro Electron Capture)
— FPD ( Flame Photometric)
©2011 Waters Corporation 24
Agilent 6850 GC
Inlet: Split/Splitless &
Purged Pack
— limits, ramps, and hold
times
Cool On-Column inlet
project in progress
Detector options:
— FID (Flame Ionization)
— TCD (Thermal
Conductivity)
©2011 Waters Corporation 25
Agilent HS7694 Headspace Sampler
Introduced July, 2003
The first
Headspace/GC system
control option in a
compliance-friendly
CDS
G1289B and G1290B
©2011 Waters Corporation 26
Agilent G1888 Headspace Sampler
Headspace Control Option
— Will continue support for the 7694
— Will add support for the G1888
— Will allow remote operation through a
LAC/E module
©2011 Waters Corporation 27
Tekmar HT3 GC Headspace
Tekmar HT3™ Static and Dynamic Headspace System driver available
from Teledyne Tekmar
Static Headspace analysis: robust technique for volatile compounds
analysis of in almost any matrix.
Dramatic improvements in sensitivity by new Dynamic Headspace
option, while maintaining ruggedness and reliability of traditional
Static Headspace.
©2011 Waters Corporation 28
Varian 39XL GC
Drivers available from Varian Product Sales
Single 1177 split/splitless or 1041 injector equipped with Injector
Electronic Flow Control, FID or TCD detector with Electronic Flow
Control
Option: keypad and
Ethernet communications
©2011 Waters Corporation 29
CTC PAL Injection Systems
LC PAL, GC PAL and Combi PAL drivers available from CTC Analytics
Automated GC and LC injection systems
Outstanding performance and maximum flexibility in every LC sample
processing system
Provides powerful working capabilities and maximum flexibility in
every GC sample processing system
Combi PAL, the only GC sample injection system combining liquid,
large volume, headspace, in tube extraction in a single instrument.
©2011 Waters Corporation 30
Beckman CE Systems
Beckman P/ACE MDQ & PA 800 Capillary Electrophoresis Systems
Control includes photo diode array and selectable wavelength UV/Vis
(with 200, 214, 254 and 280 nm filters) detector, UV source optics,
temperature-controlled sample storage module and LIF Detector
Beckman CE Control License includes instrument control software,
license, documentation, and an IEEE-to-Ethernet converter to connect
Beckman CE (IEEE-488) via Ethernet
Support for the LIF (Laser-Induced Fluorescence) detector
©2011 Waters Corporation 31
Selerity Polaratherm 9000 Total Temperature Controller
Selerity Polaratherm
9000 Total Temperature
Controllero Temperature
programmed HPLC is
taken to extremes with
the Polaratherm™ Series
9000 Total Temperature
Controller with mobile
phase preheating, and
optional cryo cooling.
©2011 Waters Corporation 32
Shimadzu Prominence LC 20 System
Prominence LC 20 drivers available from Shimadzu
Availability expected 3Q, 2007
Supported Modules— System Controller - CBM-20A, CBM-20A lite
— Pump - LC-20AD, LC-20AT, LC-20AB
— Autosampler - SIL-20A, SIL-20AC, Rack Changer, Rack Changer/C
— Column Oven - CTO-20A, CTO-20AC
— Detector - SPD-20A, SPD-20AV, SPD-M20A (PDA)
— Solenoid valve - LPGE unit built in LC-20AD/20AT
— Rotary valve - FCV-12AH installed in CTO-20A/20AC
— Rotary valve - FCV-14AH installed in CTO-20A/20AC
— Analog input - PC-55N
©2011 Waters Corporation 33
Shimadzu GC
GC System Shimadzu GC-2010
GC System Shimadzu GC-2010 Plus
GC System Shimadzu GC-2014
GC Autosampler Shimadzu AOC-20i
GC Autosampler Shimadzu AOC-20i/s
©2011 Waters Corporation 34
PerkinElmer Clarus GC
PerkinElmer Clarus 400 GC
PerkinElmer Clarus 500 GC
PerkinElmer Clarus 600 GC
©2011 Waters Corporation 35
•TurboMatrix Headspace samplers
Perkin Elmer GC and HS
©2011 Waters Corporation 36
Hitachi LaChrom Elite Systems
LaChrom Elite System drivers available from Hitachi
Availability expected 4Q, 2007
Supported Modules— L-2100 and L-2130 - Pump
— L-2200 - Autosampler
— L-2300 and L-2350 - Column Oven
— L-2400 - UV Detector
— L-2420 - UV / Vis Detector
— L-2450 and L-2455 - Diode Array Detector
— L-2480 and L-2485 - Fluorescence Detector
— L-2490 - Refractive Index Detector
— AID - Analog Input Device (Single Channel)
©2011 Waters Corporation 37
Hitachi LaChromUltra
Hitachi LaChromUltra L-2160U Pump
Hitachi LaChromUltra L-2200U Autosampler
Hitachi LaChromUltra L-2400U UV Detector
Hitachi LaChromUltra L-2420U UV-Vis Detector
Hitachi LaChrom L-2455U Diode Array Detector
Hitachi LaChromUltra L-2485U Fluorescence Detector
©2011 Waters Corporation 38
ESA Biosciences
ESA pump,
ESA Coulochem III electrochemical detector,
ESA Corona, Corona Plus, Corona Ultra CAD detectors,
CAD v1.23 Detector
Corona Plus V1.23
Corona Ultra V1.05
©2011 Waters Corporation 39
Dionex UltiMate 3000/
UltiMate 3000/3000 RSLC LPG-3400SD Quaternary Analytical pump
UltiMate 3000/3000 RSLC LPG-3400BM Quaternary Biocompatible Micro pump
UltiMate 3000/3000 RSLC DGP-3600 pumps
UltiMate 3000/3000 RSLC DGP-3600RS rapid separation dual low-pressure gradient pump
UltiMate 3000/3000 RSLC DGP-3600SD analytical dual low-pressure gradient pump
UltiMate 3000/3000 RSLC DGP-3600BM biocompatible dual low-pressure gradient pump
UltiMate 3000/3000 RSLC HPG-3x00 pumps
UltiMate 3000/3000 RSLC HPG-3x00RS rapid separation high-pressure gradient pump
UltiMate 3000/3000 RSLC HPG-3x00SD analytical high-pressure gradient pump
UltiMate 3000/3000 RSLC ISO-3100 pumps
UltiMate 3000/3000 RSLC ISO-3100SD analytical isocratic pump
UltiMate 3000/3000 RSLC ISO-3100BM biocompatible isocratic micro pump
UltiMate 3000/3000 RSLC FLM-3x00 flow managers and termostatted column compartments
UltiMate 3000/3000 RSLC TCC-3X00(RS) thermostatted column compartments
UltiMate 3000/3000 RSLC ACC-3000 autosampler column compartment
UltiMate 3000/3000 RSLC WPS-3000(RS) autosamplers
UltiMate 3000/3000 RSLC DAD-3000(RS) diode-array detector
UltiMate 3000/3000 RSLC FLD-3x00(RS) fluorescence detector
UltiMate 3000/3000 RSLC MWD-3000(RS) multi-wavelength detector
UltiMate 3000/3000 RSLC VWD-3x00(RS) variable-wavelength detectors
©2011 Waters Corporation 40
Dionex IC systems
Control of Dionex range of IC systems under development
— ICS-5000 Reagent-Free™ IC System
— ICS-2100 Integrated Reagent-Free IC System
— ICS-1600 Standard Integrated IC System
— ICS-1100 Basic Integrated IC System
— ICS-900 Starter Line IC System
©2011 Waters Corporation 41
Benefit to the Users: One Software solution for all
chromatographic systems
— Reduced Training, Validation and Support
Instrument Control Available Today
— 16 Vendors with 235+ Instrument modules
— Major LC and GC Vendors
New Techniques
— Supercritical Fluid Chromatography (SFC)
— Capillary Electrophoresis (CE)
Extended Instrument Control with Empower Software
©2011 Waters Corporation 42
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