Download - Backed by peer-reviewed, real-world evidence...ECHELON FLEX Powered Staplers are backed by large-scale, real-world, peer-reviewed evidence demonstrating improved outcomes 1 Since 2017,

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Explore study details by clicking the links below

Bariatric

US 2020Reduced hemostasis-related complications and reduced hospital costs in laparoscopic sleeve gastrectomy

US 2017Reduced hemostasis-related complications, reduced hospital costs and improved efficiency in laparoscopic bariatric procedures

Thoracic

Japan 2020 Reduced hemostasis-related complications in pulmonary artery transection

Korea 2019 Reduced hemostasis-related complications, reduced hospital costs and improved efficiency in VATS lobectomy

US 2018Reduced hemostasis-related complications, reduced hospital costs and improved efficiency in VATS lobectomy

US 2018Reduced perioperative air leaks in physiologic lung model1 Based on literature search performed May 2019. Large-scale is defined as sample size greater than 3,500 cases. 2 Miller DL, Roy S, Kassis ES, et al. Impact of Powered and Tissue-Specific Endoscopic Stapling

Technology on Clinical and Economic Outcomes of Video-Assisted Thoracic Surgery Lobectomy Procedures: A Retrospective, Observational Study. Adv Ther. 2018 Apr 16. doi: 10.1007/s12325-018-0679-z. Review of 3,006 cases between 2012 and 2016 from the Premier Healthcare Database (8.2% vs 13.9%; p=0.0218). 3 Miller DL, Roy S, Kassis ES, et al. Impact of Powered and Tissue-Specific Endoscopic Stapling Technology on Clinical and Economic Outcomes of Video-Assisted Thoracic Surgery Lobectomy Procedures: A Retrospective, Observational Study. Adv Ther. 2018 Apr 16. doi: 10.1007/s12325-018-0679-z. Review of 3,006 cases

between 2012 and 2016 from the Premier Healthcare Database ($23,785 vs $26,180; p=0.0078). 4 DRG data from 2012–2017, comparing Powered Endocutters across manufacturers.

Backed by large-scale, real-world evidence

5studies

4countries

700+hospitals

40+authors

41,500+patients

Reduced hemostasis-related

complications2

Reduced hospital costs3

Improved efficiency

Market share

LeadersPowered

laparoscopic staplers4

Echelon Flex™

Backed by peer-reviewed, real-world evidence

ECHELON FLEX™ Powered Staplers are backed by large-scale, real-world, peer-reviewed evidence demonstrating improved outcomes1

Since 2017, the use of ECHELON FLEX™ Powered Staplers has demonstrated an association with improved clinical and economic outcomes—across tissue types, patient populations and countries—in bariatric and thoracic procedures.

Demonstated improved results


Bariatric



Thoracic




US 2018Reduced perioperative air leaks in physiologic lung model

Home

Hemostasis-related complications1

US 2020

Reduced hemostasis-related complications and reduced hospital costs in laparoscopic sleeve gastrectomy

Total median hospital costs2

Comparative effectiveness assessment of two powered surgical stapling platforms in laparoscopic sleeve gastrectomy: a retrospective matched study

Johnson BH, Johnston S, Elangovanraaj N, Fortin S, Fryrear R II, Roy SValue in Health 2020; 23 Suppl 1:S188-9

40 hospitals

5,573 patients

ECHELON FLEX™ Powered Stapler with GST Reloads vs. Medtronic Signia™ with Tri-Staple™ Reload

1 Rawlins L, Johnson BH, Johnston SS, et al. Comparative Effectiveness Assessment of Two Powered Surgical Stapling Platforms in Laparoscopic Sleeve Gastrectomy: A Retrospective Matched Study. Medical Devices: Evidence and Research. 2020:13 195–204. doi: https://doi.org/10.2147/MDER.S256237. Analysis of hemostasis-related complication outcomes from 982 laparoscopic sleeve gastrectomy cases between March 1, 2017 and December 31, 2018 from Premier Healthcare Database (0.61% versus 2.24%, p=0.0012). 2 Retrospective analysis of median total hospital cost outcomes from 982 laparoscopic sleeve gastrectomy cases between March 1, 2017 and December 31, 2018 from Premier Healthcare Database ($9,771 vs. $10,487, p

14%n = 21,466

OR time3

13%n = 21,466

Total hospital costs2


Bariatric



Thoracic





Home

Reduced hemostasis-related complications, reduced hospital costs and improved efficiency in laparoscopic bariatric procedures

1 Use of Ethicon powered staplers was associated with fewer bleeding/transfusion complications (1.61%) compared to Medtronic non-powered staplers (3.05%), p=0.010, in laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass procedures. Based on retrospective analysis of 21,466 cases from the Premier Perspective® Hospital Database. 2 Use of Ethicon powered staplers was associated with lower overall hospital costs ($12,261) compared to Medtronic non-powered staplers ($14,038), p=0.022, in laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass procedures. Based on retrospective analysis of 21,466 cases from the Premier Perspective® Hospital Database. 3 Use of Ethicon powered staplers was associated with shorter OR time (133 minutes) compared to Medtronic non-powered staplers (154 minutes), p=0.011, in laparoscopic Sleeve Gastrectomy and Roux-en-Y Gastric Bypass procedures. Based on retrospective analysis of 21,466 cases from the Premier Perspective® Hospital Database.

47%n = 21,466

Hemostasis-related complications1

Comparison of economic and clinical outcomes between patients undergoing laparoscopic bariatric surgery with powered vs. manual endoscopic surgical staplers

Roy S, Yoo A, Yadalam S, Fegelman EJ, Kalsekar I, Johnston SSJournal of Medical Economics 2017;20(4):423-33

600+ hospital database

31,409 patients

US 2017

3

ECHELON FLEX™ Powered Stapler with GST Reloads vs. Medtronic Endo GIA™ with Tri-Staple™ Reload

3

Read full study

https://www.tandfonline.com/doi/full/10.1080/13696998.2017.1296453https://www.tandfonline.com/doi/full/10.1080/13696998.2017.1296453https://www.tandfonline.com/doi/full/10.1080/13696998.2017.1296453https://www.tandfonline.com/doi/full/10.1080/13696998.2017.1296453


Bariatric



Thoracic





4

HomeJapan 2020

Nobleeding

18%bleeding

ECHELON FLEX™ PVS cases

Medtronic Endo GIA™ iDrive™ cases

Bleeding1

Reduced hemostasis-related complications in pulmonary artery transection1

The impact of endoscopic stapler selection on bleeding at the vascular stump in pulmonary artery transection

Tsunezuka Y, Tanaka N, Fujimori H Medical Devices: Evidence and Research 2020;13:41-4

ECHELON FLEX™ Powered Vascular Stapler vs. Medtronic Endo GIA™ iDrive™ with Tri-Staple™ Reload

1 The impact of endoscopic stapler selection on bleeding at the vascular stump in pulmonary artery transection. Medical Devices: Evidence and Research 2020;13:41-4. Review of 239 cases between 2012 and 2018 at Ishikawa Prefectural Central Hospital. Bleeding cases results ECHELON FLEX™ PVS (0/82 cases) vs. Medtronic Endo GIA™ iDrive™ (17/94 cases). 2 The impact of endoscopic stapler selection on bleeding at the vascular stump in pulmonary artery transection. Medical Devices: Evidence and Research 2020;13:41-4. Review of 239 cases between 2012 and 2018 at Ishikawa Prefectural Central Hospital. Tunica media and intima rupture results ECHELON FLEX™ PVS (0/82 cases) vs. Medtronic Endo GIA™ iDrive™ (5/61 cases).

Read full study

1 hospital

239 patients

n = 176

https://www.dovepress.com/the-impact-of-endoscopic-stapler-selection-on-bleeding-at-the-vascular-peer-reviewed-article-MDERhttps://www.dovepress.com/the-impact-of-endoscopic-stapler-selection-on-bleeding-at-the-vascular-peer-reviewed-article-MDERhttps://www.dovepress.com/the-impact-of-endoscopic-stapler-selection-on-bleeding-at-the-vascular-peer-reviewed-article-MDERhttps://www.dovepress.com/the-impact-of-endoscopic-stapler-selection-on-bleeding-at-the-vascular-peer-reviewed-article-MDER


Bariatric



Thoracic





5

Home

1 hospital

275 patients

28%

OR time3

12%

Total hospital costs2

Korea 2019

56%

Clinical and economic benefits associated with the use of powered and tissue-specific endoscopic staplers among the patients undergoing thoracoscopic lobectomy for lung cancer

Park SY, Kim DJ, Mo Nam C, Park G, Byun G, Park H, Choi JHJournal of Medical Economics 2019;22(12):1274-80

ECHELON FLEX™ Powered Stapler with GST Reloads and ECHELON FLEX™ Powered Vascular Stapler vs. non-powered staplers

Reduced hemostasis-related complications, reduced hospital costs and improved efficiency in VATS lobectomy1,2,3

Intraoperative blood loss1

1 Park SY, Kim DJ, Nam CM, et al. Clinical and Economic benefits Associated with the Use of Powered and Tissue-specific Endoscopic Staplers Among Patients Undergoing Thoracoscopic Lobectomy for Lung Cancer. Journal of Medical Economics, DOI: 10.1080/13696998.2019.1634081. Review of 275 cases between 2008 and 2016 from Yonsei University College of Medicine, Seoul, Korea (182.4 ± 328.7ml vs. 79.8 ±110.0ml; p=0.0004). 2 Park SY, Kim DJ, Nam CM, et al. Clinical and Economic benefits Associated with the Use of Powered and Tissue-specific Endoscopic Staplers Among Patients Undergoing Thoracoscopic Lobectomy for Lung Cancer. Journal of Medical Economics, DOI: 10.1080/13696998.2019.1634081. Review of 275 cases between 2008 and 2016 from Yonsei University College of Medicine, Seoul, Korea ($12,281 vs. $10,822; p


Bariatric



Thoracic





6

Home

47%1 9%2 17%3

Ethicon powered staplers vs. Medtronic non-powered staplers, n = 3,006 41%4 9%5 14%6

ECHELON FLEX™ Powered Vascular Stapler + another Ethicon powered stapler vs. Medtronic non-powered staplers, n = 1,051

66%7 No difference 14%8

1 Miller DL, Roy S, Kassis ES, et al. Impact of Powered and Tissue-Specific Endoscopic Stapling Technology on Clinical and Economic Outcomes of Video-Assisted Thoracic Surgery Lobectomy Procedures: A Retrospective, Observational Study. Adv Ther. 2018 Apr 16. doi: 10.1007/s12325-018-0679-z. Review of 3,759 cases between 2012 and 2016 from the Premier Healthcare Database (16.0% vs. 8.5%; p=0.0004). 2 Miller DL, Roy S, Kassis ES, et al. Impact of Powered and Tissue-Specific Endoscopic Stapling Technology on Clinical and Economic Outcomes of Video-Assisted Thoracic Surgery Lobectomy Procedures: A Retrospective, Observational Study. Adv Ther. 2018 Apr 16. doi: 10.1007/s12325-018-0679-z. Review of 3,759 cases between 2012 and 2016 from the Premier Healthcare Database ($23,841 vs. $26,052; p=.0087). 3 Miller DL, Roy S, Kassis ES, et al. Impact of Powered and Tissue-Specific Endoscopic Stapling Technology on Clinical and Economic Outcomes of Video-Assisted Thoracic Surgery Lobectomy Procedures: A Retrospective, Observational Study. Adv Ther. 2018 Apr 16. doi: 10.1007/s12325-018-0679-z. Review of 3,759 cases between 2012 and 2016 from the Premier Healthcare Database (4.87 days vs. 5.88 days; p


Bariatric



Thoracic




HomeUS 2018

First-of-its-kind physiologic lung model, designed to simulate both ventilated and physiologic breathing to collect and measure air leaks by incidence and volume.

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1 Staple line air leaks in porcine lungs using a physiologically-based ex-vivo lung chamber model. ECHELON FLEX™ GST System vs Endo GIA™ with Tri-Staple™ Technology. 20% vs 44%, GST 45 Blue & Green reloads vs Tri-Staple™ 45 Purple & Black, (n=110). Based on similar design features between ECHELON GST45 & GST60, no significant difference in performance is expected.

Preclinical quantification of air leaks in a physiologic lung model: effects of ventilation modality and staple design

Eckert CE, Harris JL, Wong JB, Thompson S, Kassis ES, Tsuboi M, Ott HC, Force SMedical Devices: Evidence and Research 2018;11:433-42

110 porcine lung sets

ECHELON FLEX™ Powered Stapler with GST Reloads vs. Medtronic Endo GIA™ with Tri-Staple™ Reload

Reduced perioperative air leaks in physiologic lung model

2x

ECHELON FLEX™ Powered Stapler with GST Reloads

44%Endo GIA™ with Tri-Staple™ Technology 20%

fewer staple line air leaksECHELON FLEX™ Powered Stapler with GST Reloads1

Read full study


https://pubmed.ncbi.nlm.nih.gov/30588134/https://pubmed.ncbi.nlm.nih.gov/30588134/https://pubmed.ncbi.nlm.nih.gov/30588134/https://pubmed.ncbi.nlm.nih.gov/30588134/

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