XXIXth International Workshop - Helicobacter · 2014 Manfred Kist, Freiburg, Germany 2013 Masahiro...

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XXIXth International Workshop on Helicobacter & Microbiota in Inflammation and Cancerin conjunction with the EAGEN/EHMSG Postgraduate CourseGastrointestinal Microbiota in Health and Disease. What is the current evidence?

September 15 – 17, 2016 | Magdeburg | Germany

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Scan this QR code to dowload the programmes of the EHMSG Workshop, the EAGEN/EHMSG Postgraduate Course and useful information about Magdeburg as pdf file.You may need to download a QR code scanner in the App Store or Google Play Store.

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XXIXth International Workshop on Helicobacter and Microbiota in Inflammation and Cancerin conjunction with the EAGEN/EHMSG Postgraduate Course

“Gastrointestinal Microbiota in Health and Disease. What is the current evidence?”

Magdeburg, GermanySeptember 15 - 17, 2016

www.ehmsg.org

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TABLE OF CONTENTS

Awardees of the Marshall and Warren Medal................................................................................................ 4

Welcoming Addresses ................................................................................................................................... 5

Committees – Organisation ........................................................................................................................... 8

Workshops of the EHMSG ............................................................................................................................ 8

Map of the Venue .......................................................................................................................................... 9

Programme at a Glance .............................................................................................................................. 10

Scientific Programme

- Friday, September 16 ............................................................................................................................. 12

- Saturday, September 17 ......................................................................................................................... 16

EAGEN Postgraduate Workshop, Thursday, September 15 ....................................................................... 20

Corporate Satellites ..................................................................................................................................... 22

Public Event - Healthy Stomach Initiative .................................................................................................... 23

Scientific Information, Poster Schedule ....................................................................................................... 24

Acknowledgements ..................................................................................................................................... 26

General Information ..................................................................................................................................... 28

Registration Details ..................................................................................................................................... 30

Networking Events....................................................................................................................................... 30

AWARDEES OF THE MARSHALL & WARREN MEDAL

2016 Ken Sugano, Shimotsuke, Japan2015 Heidi-Ingrid Maaroos, Tartu, Estonia2014 Manfred Kist, Freiburg, Germany2013 Masahiro Asaka, Sapporo, Japan2012 Richard Hunt, Hamilton, ON, Canada2011 Samy Cadranel, Brussels, Belgium2010 Reinhold W. Stockbrügger, Maastricht, The Netherlands2009 Pelayo Correa, Nashville, TN, United States2008 Timo Kosunen, Helsinki, Finland2007 Mike Dixon, Leeds, United Kingdom2006 Barry Marshall, Perth, Australia & Stanislav Konturek, Cracow, Poland

NEXT EHMSG WORKSHOP

Bordeaux, France, September 7-9, 2017

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WELCOMING ADDRESSES

Welcoming address by the Minister President of Saxony-Anhalt Dr. Reiner Haseloff

Dear ladies and gentlemen,

The federal state Saxony-Anhalt has always been a home for outstanding researchers, but scientific structures, specialised fields and personnel were subjected to a comprehensive reorganisation process following the reunification of Germany. Currently, the scientific location Saxony-Anhalt can hold its own against other regions in Germany and abroad. Two universities both with medical faculties form the core alongside four universities of applied sciences: all these institutions are highly attractive for researchers and students alike. Numerous students from abroad are also keen to study in our federal state; in 2015, a total of around 55 000 students were registered at universities in Saxony-Anhalt.

Science and research are however not an end in themselves, but additionally benefit social and economic progress. Economic growth is increasingly determined by the augmentation in the creation of value fuelled by education and research. Major corporations have their own extensive research departments, but our economy is chiefly shaped by small and medium-sized companies who are unable to afford their own R&D departments. 95 % of these companies have fewer than 20 employees which makes cooperation between firms and universities, universities of applied sciences and non-university institutes all the more essential. Our federal state has already developed a healthy structure within the non-university sector, and major research societies are involved in collaborations with numerous institutes.

The dovetailing of economic and scientific sectors is a key focus of our federal government. Our objective is to encourage innovation and increase competitive ability in Saxony-Anhalt. Numerous companies are already working together in networks and clusters among themselves and in collaboration with research institutions, but there is still potential for further growth. This is why we would like to progress further along our adopted path.

Against this background, the new federal government has committed itself to the promotion of this cause. We aim to continue our support for top-class research and build further on our existing strengths. This will help us not only to retain young highly qualified experts already established here, but also attract new specialists to our federal state.

It is a good sign that a gastroenterological-microbiological interactive congress with top-level international participation is being held in Magdeburg. I wish all participants great success during the course of this event.

Dr. Reiner HaseloffMinister President of the federal state Saxony-Anhalt

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WELCOMING ADDRESSES Welcoming address by the Mayor of the city of Magdeburg Dr. Lutz Tümper

Dear scientists, dear friends and clinical researcher,

It is my great pleasure to welcome you to the capital of Sachsen-Anhalt! Magdeburg is a lively city with many students and a continuously expanding landscape of science and education. Events like the congress of the European Helicobacter and Microbiota Study Group are an exciting occasion for this evolution. An important contribution to the promotion of Magdeburg for many years has come from research on gastrointestinal and liver diseases at the University Clinic of Gastroenterology, Hepatology and Infectious Diseases under the direction of Prof. Peter Malfertheiner. His engagement to contribute to Magdeburg as a location of research and to bring a world-class scientific congress to the city is highly appreciated.

I wish you an outstanding meeting with exciting presentations of new scientific data, vivid exchanges and a wonderful stay in the “Otto City” of Magdeburg.

Yours,

Dr. Lutz TrümperMayor of the city of MagdeburgOberbürgermeister der Landeshauptstadt Magdeburg

Welcoming address by the President of the Otto-von-Guericke University of Magdeburg Prof. Dr.-Ing. Jens Strackeljan

Dear Delegates, Scientists and Clinicians,

I would like to welcome you to our city on the occasion of the European Helicobacter and Microbiota Study Group – EHMSG XXIXth International Workshop on Helicobacter and Microbiota in Inflammation and Cancer.

We are proud to learn that you are travelling from all around the world to meet here in Magdeburg for the exchange of the most recent developments in basic science and clinical translation of one of the major microbial threats for human health. Furthermore you will be able to discuss new opportunities for the maintenance of human health through the intriguing interaction of gut microbiota with their hosts. The University of Magdeburg has a long tradition in engineering, medical and natural sciences and is ambitiously anticipating continuous growth in the future. It is our vision to keep the doors of the Otto-von-Guericke University open for students and academicians from all over the world.

We wish you pleasant and inspiring days in Magdeburg and hope you will take important new information and memorable events back home with you.

All the best for you.

Prof. Dr.-Ing. Jens StrackeljanPresident of the Otto-von-Guericke University of Magdeburg

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WELCOMING ADDRESSES

Welcoming address by the President of the European Helicobacter and Microbiota Study GroupProf. Dr. Peter Malfertheiner

Dear Delegates, Colleagues and Friends,

Welcome to the XXIXth International Workshop of the European Helicobacter and Microbiota Study Group, welcome to Magdeburg. After 3 decades of intensive research on H. pylori, the persisting “intruder” of the human gastric mucosa, we are still facing the challenge to unravel many facets of this intriguing bug and to optimize the management of patients carrying the infection. H. pylori is the opener of a new genus that led to the discovery of other Helicobacters in the whole animal world.

H. pylori has pioneered the field of gut microbiota and their numerous functions in health and disease and thus may well be considered “the conductor of the gut microbiota orchestra”. Gut microbiota have become the extension line of our common scientific interests.

We feel honored by your participation in this event, grateful to you for providing new insights and for inspiring, fruitful discussions to nourish the enthusiasm in this exciting field.

We are proud to host this event in Magdeburg, the city with a long history of important cultural and scientific traditions. One famous example: the Magdeburg hemispheres, designed by the German scientist and mayor of Magdeburg Otto von Guericke, demonstrating the principle in physics. The hemispheres of Magdeburg may serve as a symbol and incentive to find easy solutions for seemingly difficult scientific tasks. Scientific progress needs to be conveyed to the general public, therefore -and for the first time of our EHMSG congresses- we have arranged for a public awareness event with the Healthy Stomach Initiative, presenting a walkable stomach outside of our EHMSG congress venue.

We wish you a pleasant stay and hope you will be able to take good scientific and social memories with you. Yours,

Peter MalfertheinerPresident of EHMSG

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COMMITTEES – ORGANISATION

Local Organizing Committee

Local Organising CommitteePeter Malfertheiner, GermanyMarino Venerito, GermanyChristian Schulz, GermanyDaniela Deutschländer, Germany

Scientific Committee Steffen Backert, GermanyWolfgang Fischbach, Germany Rainer Haas, Germany Sibylle Koletzko, Germany Joachim Labenz, Germany

Julia Mayerle, Germany Thomas Meyer, Germany Michael Naumann, Germany Michael Selgrad, Germany Sebastian Suerbaum, Germany Michael Vieth, Germany

European Helicobacter and Microbiota Study Group (EHMSG)PresidentPeter Malfertheiner, Germany

MembersLeif P. Andersen, DenmarkLars Engstrand, SwedenBram Flahou, BelgiumAntonio Gasbarrini, ItalyJavier P. Gisbert, SpainGeorgina L Hold, United KingdomErnst Kuipers, The NetherlandsMarcis Leja, LatviaJosé C. Machado, PortugalFrancis Mégraud, FranceColm A. O’Morain, IrelandAri P. Ristimäki, FinlandTheodore Rokkas, GreeceHerbert Tilg, Austria

Honorary MembersFranco Bazzoli, ItalyJames G. Fox, United StatesDavid Y. Graham, United StatesAdrian Lee, AustraliaBarry Marshall, AustraliaGuido N.J. Tytgat, The Netherlands

Emeritus MembersAnthony Axon, United KingdomMichel A.L. Deltenre, BelgiumGiovanni Gasbarrini, ItalyAlexander M. Hirschl, AustriaPierre Michetti, SwitzerlandJosé M. Pajares Garcia, SpainAshley B. Price, United KingdomMario G. Quina, PortugalErik A.J Rauws, The NetherlandsPentti I. Sipponen, FinlandTorkel M. Wadström, Sweden

Corresponding FellowsNiyaz Ahmed, IndiaLuiz G. Vaz Coehlo, BrazilToshio Fujioka, JapanHyun Chae Jung, KoreaVarocha Mahachai, ThailandYaron Niv, IsraelShu Dong Xiao (), China

Organising OfficesCore Agency Vienna Medical AcademyAlser Strasse 41090 Vienna, AustriaPhone: +43 1 405 13 83 0Fax: +43 1 407 82 [email protected]

Local AgencyDestination Services Europe GmbH Nuellerstrasse 48 42115 Wuppertal, Germany Phone: +49-202-8702991 Fax: +49-202-2572291 Email: [email protected]

Workshops of the EHMSG• Bordeaux (1988)• Ulm (1989) • Toledo (1990)• Bologna (1991) • Dublin (1992) • Brussels (1993) • Houston (1994) • Edinburgh (1995)• Copenhagen (1996)• Lisbon (1997)

• Budapest (1998) • Helsinki (1999) • Rome (2000) • Strasbourg (2001) • Athens (2002)• Stockholm (2003)• Vienna (2004)• Copenhagen (2005)• Wroclaw (2006)• Istanbul (2007)

• Riga (2008)• Porto (2009)• Rotterdam (2010)• Dublin (2011)• Ljubljana (2012)• Madrid (2013)• Rome (2014)• Nicosia (2015)• Magdeburg (2016)• Bordeaux (2017)

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MAP OF THE VENUE

Bluethner Saal

Breakout Room 1

Exhibition

Registration

Exhibtion

to Main Hall

Exhibition

MainEntrance

to Gartenhaus

Breakout Room 2

Stadthalle Magdeburg

Ground Floor

Stadthalle Magdeburg

Second Floor

Main HallMai

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Sta

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Poster Exhibition

Stage

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PROGRAMME AT A GLANCE

Thursday, September 15, 2016

08:30 - 17:00 hrs EAGEN/EHMSG Postgraduate CourseGastrointestinal Microbiota in Health and Disease. What is the current evidence?

Hotel Herrenkrug

08:35 - 09:55 hrs Gastrointestinal Microbiota in Health Festsaal

09:55 - 10:40 hrs Antibiotics and the Gut Microbiota Festsaal

10:40 - 11:00 hrs Coffee Break11:00 - 12:45 hrs Gastrointestinal Microbiota in Disease Festsaal

12:45 - 14:00 hrs Lunch14:00 - 15:00 hrs 5 Messages for each TOPIC Festsaal

15:00 - 15:45 hrs Coffee Break15:45 - 16:30 hrs Gastrointestinal Microbiota as Therapeutic Principles Festsaal

16:30 - 17:00 hrs Meet the Professor in Round Table Festsaal

18:00 - 20:00 hrs Opening Ceremony and Networking Event Stadthalle Magdeburg, Bluethnersaal

Friday, September 16, 2016

08:00 - 18:50 hrs XXIXth International Workshop of the EHMSG - Day 1 Stadthalle Magdeburg

08:00 - 08:15 hrs Welcoming Addresses Main Hall

08:15 - 09:15 hrs Opening Conference: Evolutionary Aspects of Human Kind and Gut Microbiota Main Hall

09:15 - 10:00 hrs Plenary Workshop 1 Main Hall

10:00 - 10:30 hrs Coffee Break

10:30 - 11:00 hrs The Year in Helicobacter Main Hall

11:00 - 11:30 hrs Plenary Workshop 2 Main Hall

11:30 - 13:00 hrs Parallel Workshops from Submitted Abstracts

Workshop 1: Diagnosis, Epidemiology & Pediatrics Gartenhaus

Workshop 2: Inflammation, Immunity, Vaccines, Host interaction Bluethnersaal

13:00 - 14:00 hrs Satellite Symposium Main Hall

14:00 - 15:00 hrs Lunch Break and Poster Rounds from Submitted Abstracts Poster Area

15:00 - 16:30 hrs Symposium: Advances of Endoscopic Imaging in Infectious and Non-Infectious Diseases Main Hall


17:00 - 18:30 hrs Parallel Workshops with Key Point Lectures and Submitted Abstracts infectious diseasesWorkshop 3: Treatment & Drug Resistance GartenhausWorkshop 4: Virulence Factors, Pathogenesis and Inflammation Bluethnersaal

18:30 - 18:50 hrs Special Lecture: Gut Microbiota Main Hall

20:00 hrs EHMSG Networking Dinner Jahrtausend Turm

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PROGRAMME AT A GLANCE

Saturday, September 17, 2016

08:15 - 19:15 hrs XXIXth International Workshop of the EHMSG - Day 2 Stadthalle Magdeburg

08:15 - 10:00 hrs Symposium: H. pylori Infection and Host Interaction Main Hall


10:30 - 11:30 hrs The Year in Gut Microbiota Main Hall

11:30 - 13:00 hrs Parallel Workshops from Submitted Abstracts

Workshop 5: Gastric Cancer and Carcinogenesis Gartenhaus

Workshop 6: Helicobacters and Extragastric Diseases Bluethnersaal

13:00 - 14:00 hrs Satellite Symposium Main Hall


15:00 - 15:45 hrs Symposium Gut Microbiota in Cancer Main Hall

15:45 - 16:30 hrs Plenary Workshop 3: Microbiota Main Hall


17.00 - 17:30 hrs New Developments Main Hall

17:30 - 19:00 hrs Symposium: Treatment and Cancer Prevention - Towards a Global Consensus Main Hall

19:00 - 19:15 hrs Awarding of the Marshall and Warren Medal to Ken SuganoEHMSG Presentation and Poster Awards

Presentation of the next meeting in Bordeaux, FranceClosing remarks

Main Hall

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PROGRAMME FRIDAy, SEPTEMBER 16

08:00 - 08:15 hrs Welcoming Addresses Main Hall

Mayor of the city of Magdeburg, Lutz Trümper

President of the University Otto-von-Guericke, Jens Strackeljan

08:15 - 09:15 hrs Opening Conference: Evolutionary Aspects of Human Kind and Gut Microbiota Main Hall Chairpersons: Peter Malfertheiner, Francis Mégraud

Symbiotic relationship between humans and our microbes Martin Blaser, New York, NY, USA (20’)

The 5300-year-old Helicobacter pylori genome of the Iceman Frank Maixner, Bolzano, Italy (20’)

Neanderthal DNA, Helicobacter pylori and the human immune system Michael Dannemann, Leipzig, Germany (20’)

09:15 - 10:00 hrs Plenary Workshop 1 Main Hall Chairpersons: Karen Robinson, Georgina Hold

PW1.1 The presence of H.pylori significantly alters the pattern of the active bacterial community in gastric mucosa- a 16sRNA - deep sequencing approach Christian Schulz, K. Schütte, N. Koch, R. Vilchez-Vargas, M. Vital, P. Malfertheiner, D. H. Pieper, Magdeburg, Germany (10’)

PW1.2 SHP1 is the Helicobacter pylori CagA-specific phosphatase that is dampened by Epstein-Barr virus P. Saju, N. Murata-Kamiya, Masanori Hatakeyama, Tokyo, Japan (10’)

PW1.3 Increased abundance of beneficial bacteria is associated with clinical improvement in patients receiving rifaximin treatment F. Ponziani, Franco Scaldaferri, F. Paroni Sterbini, V. Petito, S. Pecere, L. Lopetuso, A. Palladini, C. Graziani, L. Masucci, M. Pompili, G. Cammarota, M. Sanguinetti, A. Gasbarrini, Rome, Italy (10’)

PW1.4 Effect on the intestinal microbiota and Clinical outcome of faecal microbiota transplantation in patients with UC S. Paramsothy, N. O. Kaakoush, M. Kamm, J. Faith, J. C. Clemente, A. Walsh, J. van den Bogaerde, D. Samuel, R. Leong, S. Connor, W. Ng, R. Paramsothy, E. Lin, J. Colombel, T. Borody, Hazel M. Mitchell, Syd-ney, Australia (10’)

10:00 - 10:30 hrs Coffee break

10:30 - 11:00 hrs The Year in Helicobacter Main Hall Chairpersons: David Graham, Giovanni Gasbarrini

Diagnosis Colm O’Morain, Dublin, Ireland(10’)

Treatment Javier Gisbert, Madrid, Spain(10’)

Gastric cancer Ari Ristimäki, Helsinki, Finland (10’)

11:00 - 11:30 hrs Plenary Workshop 2 Main Hall Chairpersons: Sybille Koletzko, Dmitry Bordin

PW2.1 The preliminary results of GISTAR pilot study in Latvia Marcis Leja, A. Rudule, J. Y. Park, R. Murillo, I. Liepniece-Karele, S. Isajevs, I. Kikuste, D. Rudzite, P. Krike, S. Parshutin, I. Polaka, A. Kirsners, D. Santare, I. Daugule, R. Herrero, Riga,LAtvia (10’)

P2.2. Pan-European Registry on H. pylori Management (Hp-EuReg): Interim analysis of the single-cap-sule bismuth quadruple treatment (Pylera®) Adrian G. McNicholl, F. Megraud, B. Tepes, M. Venerito, K. Przytulski, J. Delchier, A. Courillon-Mallet, B. R. Molard, D. Vaira, A. Perez-Aisa, L. Fernandez-Salazar, L. Bujanda, J. Ortuño, M. G. Donday, O. P. Nyssen, C. O’Morain, J. P. Gisbert, Hp-EuReg investigators, Madrid, Spain (10’)

P2.3 A new, biologically relevant classification for adenocarcinoma at the gastroesophageal junction Jan Bornschein, J. Perner, L. Wernisch, M. Secrier, S. MacRae, A. Miremadi, M. O’Donovan, L. Bower, M. Eldridge, M. Venerito, M. Selgrad, P. Malfertheiner, R. C. Fitzgerald, Magdeburg, Germany (10’)

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Parallel Workshops from Submitted Abstracts

11:30 - 13:00 hrs Workshop 1: Diagnosis, Epidemiology & Pediatrics Gartenhaus Chairpersons: Michael Selgrad, Francesco di Mario

W1.0 Key Note: What are the challenges in Diagnosis? Yaron Niv, Petach Tikva, Israel

W1.1 Evaluation of the new kit RIDA®GENE Helicobacter pylori real-time PCR for diagnosis of Helico-bacter pylori in gastric biopsies Lucie Bénéjat, A. Ducournau, P. Lehours, F. Mégraud, Bordeaux, France

W1.2 Multiplex species-specific DNA detection of Helicobater bilis and hepaticus Daniela Höfler, J. Butt, M. Schmitz, P. Mauter, K. Schmidt, M. Pawlita, Heidelberg, Germany

W1.3 Comparison of microbiological and histological test for diagnosis of H. pylori infection. Cosima Langner, A. Link, I. Tammer, T. Wex, P. Malfertheiner, Magdeburg, Germany W1.4 Prevalence of Helicobacter pylori infection and cofactors in high and low gastric cancer risk areas of Chile: The ENIGMA 1 Study Rolando Herrero, C. Ferreccio, J. Acevedo, P. Cook, J. Gahona, C. Gonzalez, K. Heise, E. Bertran, S. Vargas, S. Rinaldi, R. Murillo, J. Park, M. Camargo, F. Megraud, A. Hildesheim, M. Hernandez, P. Gonzalez, Lyon, France

W1.5 Diagnostic accuracy of urine Helicobacter pylori antibody test in junior and senior high school students in Japan Masumi Okuda, K. Mabe, S. Kikuchi, M. Takamasa, M. Kato, M. Asaka, Sasayama, Japan W.1.6 Chronic atrophic gastritis in Italy: a population study on 10,000 people Francesco Di Mario, S. Grillo, S. Landi, M. Franceschi, F. Baldassarre, R. Cannizzaro, N. Dal Bò, A. Gnocchi, V. Corrente, A. Bertelè, C. Scarpignato, M. Rugge, Parma, Italy

11:30 - 13:00 hrs Workshop 2: Inflammation, Immunity, Vaccines, Host interaction - Bluethnersaal Chairpersons: Julia Mayerle, Leif Andersen

W2.0 Key Note: Exploitation of regulatory signatures for cell survival in Helicobacter pylori infection Michael Naumann, Magdeburg, Germany

W2.1 A new animal model of gastric lymphomagenesis? hAPRIl transgenic mice infected by Helico-bacter species. P. Floch, J. Izotte, E. Sifré, P. Costet, B. Rousseau, A. Giese, F. Mégraud, P. Dubus, H. Michael, Philippe Lehours, Bordeaux, France

W2.3 Helicobacter pylori infection can affect the immune response to oral enteric vaccines Khitam Muhsen, M. F. Pasetti, D. Y. Graham, D. Cohen, M. M. Levine, Tel Aviv, Israel

W2.4 H. pylori specific induction of Th17 immune response ex vivo and in vitro Arne Kandulski, W. Schirrmeister, A. Link, C. Langner, P. Malfertheiner, Magdeburg, Germany

W2.5 A polymorphism in Toll-like receptor-2, TLR-2 (Arg753/Gln) is functional and is associated with increased risk of duodenal ulcer. G. A. Rocha, A. M. C. Rocha, F. F. Melo, S. A. Batista, Dulciene Queiroz, Belo Horizonte, Brazil

W2.6 E3 ubiquitin ligase-dependent NF-κB regulation in Helicobacter pylori infection Olga Sokolova, A. Schmädicke, M. Rother, C. Rechner, T. Meyer, M. Naumann, Magdeburg, Germany

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13:00 - 14:00 hrs Satellite Symposium - See page 22 for more information Main Hall


Diagnosis of Helicobacter infection Chairpersons Group 1: Yaron Niv, Michael Selgrad

Chairpersons Group 2: Colm O’Morain, Adrian McNicholl

Epidemiology Chairpersons Group 1: Gerardo Nardone, Jan Bornschein

Chairpersons Group 2: Limas Kupcinskas, Manfred Kist

Paediatrics Chairpersons: Sibylle Koletzko, Mohammed Alboraie

Virulence factors and pathogenesis of Helicobacter infection Chairpersons Group 1: Julia Mayerle, Sebastian Suerbaum

Chairpersons Group 2: Thomas Wex, Han Remault

Microbiology and genomics of Helicobacter Chairpersons: Francis Mégraud, Georgina Hold

Gastric cancer and cancerogenesis Chairpersons Group 1: Bojan Tepes, Tamara Matysiak-Budnik

Chairpersons Group 2: Massimo Rugge, Marino Venerito

15:00 - 16:30 hrs Symposium: Advances in endoscopic imaging in infectious and non infectious diseases Main Hall Chairpersons: K. Sugano, P. Malfertheiner

What can HD endoscopy contribute to gut microbiota resarch? Ken Sugano, Shimotsuke, Japan (15’) Assessment of gastric atrophic changes and follow up by using advanced endoscopy imaging Raf Bisschops, Leuven, Belgium (15’)

Gastric inflammatory disease and Kyoto classification Mototsugu Kato, Hakodate, Japan (15’) Still a role for the pathologist?

Massimo Rugge, Padova, Italy (15’) Pseudomembranous colitis: before and after fecal microbiota transplantation

Jochen Weigt/Alexander Link, Magdeburg, Germany (10’)

How does HD endoscopy influence management of inflammatory bowel disease? Hendrik Manner, Wiesbaden, Germany (15’)

Gastrointestinal inflammatory diseases: Where are we heading? Peter Malfertheiner, Magdeburg, Germany (5’)


Parallel Workshops with Key Point Lectures and Submitted Abstracts

17:00 - 18:30 hrs Workshop 3: Treatment & Drug Resistance Gartenhaus Chairpersons: J. Labenz, Ki-Baik Hahm

W3.0 Key Note: What are the challenges in Treatment? Franco Bazzoli, Bologna, Italy

W3.1 Comparing 10- or 14-day sequential therapy with 10- or 14-day concomitant therapy in the first line empirical treatment of Helicobacter pylori infection Byung-Wook Kim, J. Kim, S. Park, Y. Kim, G. Kim, T. Gweon, Incheon, South Korea

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W3.2 Efficacy of 7-day genotypic resistance-guided triple therapy for Helicobacter pylori eradication N. Mathou1, S. Lycousi, Vasilios Papastergiou, K. D. Paraskeva, A. Giannakopoulos, A. Evgenidi, E. Platsou-ka, J. A. Karagiannis, Athens, Greece

W3.3 Vonoprazan-based rescue eradication therapy for patients who have ever failed in the eradica-tion of H. pylori. Takahisa Furuta, H. Ichikawa, T. Kagami, T. Suzuki, M. Yamade, Y. Hamaya, M. Iwaizumi, S. Osawa, K. Sug-imoto, Hamamatsu, Japan

W3.4 Effect of IL-1 polymorphisms, CyP2C19 genotype and antibiotic resistance for Helicobacter py-lori eradication comparing between 10-day sequential therapy and 14-day standard triple therapy with four-time-daily dosing of amoxicillin: A prospective randomize K. Phiphatpatthamaamphan, Ratha-korn Vilaichone, S. Siramolpiwat, A. Tangaroonsanti, S. Chonprasertsuk, P. Bhanthumkomol, B. Pornthisarn, V. Mahachai, Bangkok, Thailand

W3.5 Primary resistance of Helicobacter pylori to clarithromycin, levofloxacin and tetracycline in Ger-many B. Bluemel, H. Goelz, B. Eisele, Erik Glocker, Freiburg, Germany

W3.6 Antimicrobial resistance and treatment outcome for H pylori infections in Alaska Michael Bruce, D. Newbrough, D. Bruden, D. Hurlburt, J. Morris, A. Reasonover, F. Sacco, T. Hennessy, J. Kejka, B. McMahon, Anchorage, Canada

17:00 - 18:30 hrs Workshop 4: Virulence Factors, Pathogenesis and Inflammation Bluethnersaal Chairpersons: Christine Josenhans, Jose Machado, Michael Vieth

W4.0 Key Note: New insights in H. pylori virulence Karen Robinson, Nottingham, United Kingdom

W4.1 Identification of genes associated with Gastric Cancer by GWAS approach in Helicobacter pylori Elvire Berthenet, L. Mageiros, D. Falush, K. Yahara, K. Thorell, S. K. Sheppard, Swansea, United Kingdom

W4.2 Development and characterization of an inducible genetic system in Helicobacter pylori to ex-press a peptide inhibitor of serine protease HtrA N. Tegtmeyer, M. Böhm, Steffen Backert, Erlangen, Germany

W4.3 Repressed TGF-beta signaling through CagA-Smad3 interaction worsened H. pylori -associated gastritis Ki Baik Hahm, H. Lee, Y. Shin, S. Choi, Seongnam, South Korea

W4.4 H. pylori vacA genotype is a predominant determinant of immunologic response to H. pylori CagA Alexander Link, C. Langner, W. Schirrmeister, W. Habendorf, J. Weigt, M. Venerito, I. Tammer, D. Schlueter, A. Roessner, P. Schlaermann, T. Meyer, T. Wex, P. Malfertheiner Magdeburg, Germany

W4.5 Genomes of Helicobacter pylori prophages Filipa Vale, A. Nunes, M. Oleastro, J. P. Gomes, D. A. Sampaio, R. Rocha, J. Vítor, L. Engstrand, B. Pascoe, E. Berthenet, S. Sheppard, M. D. Hitchings, F. Francis Mégraud, J. Vadivedu, P. Lehours, Lisboa, Portugal

W4.6 Genome dynamics and functional molecular infection epidemiology of multidrug resistant Heli-cobacter pullorum isolated from retail wet market poultry in India S. Qumar, M. Majid, Niyaz Ahmed, Hyderabad, India

18:30 - 18:50 Special Lecture: Gut Microbiota Chairpersons: Dan L. Dumitrascu, Andreas Stallmach

Gut Microbiota in Inflammatory Bowel Disease Paul Moayyedi, Hamilton, Canada (20’)

20.00 hrs EHMSG Networking Dinner at the Jahrtausend Turm

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PROGRAMME SATURDAy, SEPTEMBER 17

08:15 - 10:00 hrs Symposium: H. pylori Infection and Host Interaction Main Hall Chairpersons: Tamara Matysiak Budnik, Rainer Haas

Structural insight in H. pylori adherence Han Remaut, Brussels, Belgium (15’) Evolution of Helicobacter and nickel metabolism Hilde de Reuse, Paris, France (15’) Genomic plasticity of H. pylori during infection Sebastian Suerbaum, Munich, Germany (15’) Oncogenic signaling during H. pylori infection Steffen Backert, Erlangen, Germany (15’) Microbe signaling at the gastric mucosa level Thomas Meyer, Berlin, Germany (15’)

Debate: H. pylori has protective potential (20’) Pro: Anne Müller, Zurich, Switzerland (10’) Contra: Joachim Labenz, Siegen, Germany (10’)

Discussion (10’)


10:30 - 11:30 hrs The Year in Gut Microbiota Main Hall Chairpersons: Mirjana Rajlic-Stojanovic, James Fox

Methodology Lars Engstrand, Solna, Sweden (15’) From taxonomic approaches towards functional based analyses Marius Vital, Hannover, Germany (15’) Fecal Microbiota Transplantation Theodore Rokkas, Athens, Greece (15’) Antibiotics - From good to evil Antonio Gasbarrini, Rome, Italy (15’)

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Parallel Workshops from Submitted Abstracts

11:30 - 13:00 hrs Workshop 5: Gastric Cancer and Carcinogenesis Gartenhaus Chairpersons: James Fox, Albert Rössner

W5.0 Key Note: What are the challenges in Gastric Cancer? Wei-Cheng You, China

W5.1 Activation of the Hippo/yAP signaling pathway in gastric epithelial cells in response to Helico-bacter pylori infection Silvia Molina-Castro, C. Staedel, S. Fernandez, J. Giraud, E. Bessède, P. Lehours, F. Mégraud, C. Varon, Bordeaux, France

W5.2 Suppressed Helicobacter pylori-associated gastric tumorigenesis in fat-1 transgenic mice pro-ducing endogenous omega-3 polyunsaturated fatty acids Ki Baik Hahm, Y. Shin, S. Choi, J. Kang, Seongnam, South Korea

W5.3 RACK1: a new player in NF-κB signaling pathway induced by Helicobacter pylori infection Yi Hu, Z. Xiong, J. Liu, Y. Zhu, N. Lv, Nanchang, China W5.4 LINE-1 hypomethylation is a rare event in preneoplastic stages of gastric carcinogenesis Juozas Kupcinskas, R. Steponaitiene, C. Langner, J. Skieceviciene, L. Kupcinskas, P. Malfertheiner, A. Link Kaunas, Lithuania

W5.5 Recovery of gastric function in chronic atrophic gastritis: a 3 years study Francesco Di Mario, S. Grillo, S. Landi, G. Grande, M. Riccò, M. Franceschi, F. Baldassarre, R. Cannizzaro, D. Nadia, A. Gnocchi, V. Corrente, A. Bertelè, M. Rugge, Parma, Italy

W5.6 Is pepsinogen screening in general Caucasian population justified: results from a cross-section-al population study in Latvia Olga Sjomina, J. Pavlova, P. Janovic, I. Kikuste, A. Vanags, I. Tolmanis, I. Polaka, I. Kojalo, I. Liepniece-Kar-ele, S. Isajevs, D. Santare, D. Rudzite, V. Pirags, J. Pahomova, V. Dzerve, A. Erglis, M. Leja, Riga, Latvia

11:30 - 13:00 hrs Workshop 6: Helicobacters and Extragastric Diseases Bluethnersaal Chairpersons: Limas Kupcinskas, Francesco Franceschi

W6.0 Key Note: H. pylori extragastric diseases - Truth and supposition Bojan Tepes, Rogaska Slatina, Slovenia

W6.1 The cytolethal distending toxin CdtB subunit of Helicobacter triggers the expression of the MafB oncoprotein in intestinal and hepatic cell lines Armelle Ménard, C. Péré-Védrenne, a. Buissonnière, J. Izotte, A. Giese, B. Cardinaud, F. Mégraud, Bordeaux, France

W6.2 Novel Helicobacter Species H. japonicum Isolated from Laboratory Mice from Japan Induces Typhlocolitis and Lower Bowel Carcinoma in C57BL/129 IL10-/- Mice Z. Shen, Y. Feng, S. Muthupalani, A. Sheh, L. E. Cheaney, C. A. Kaufman, G. Gong, B. J. Paster, James Fox, Cambridge, United States

W6.3 Helicobacter heilmannii-induced salivary and lacrimal gland lymphocytic infiltration in mouse: relation to Sjogren syndrome Masahiko Nakamura, A. Øverby, Y. Kodama, H. Matsui, S. Takahashi, Tokyo, Japan

W6.4 Associations of Helicobacter pylori infection and peptic disease with diabetic mellitus: results from a large population-based study S. Haj, G. Chodick, R. Refalei, S. Goren, V. Shalev, Khitam Muhsen, Tel Aviv, Israel

W6.5 Cytolethal distending toxin promotes intestinal carcinogenic potential of Helicobacter hepaticus in 129Rag2-deficient Mice Zhongming Ge, L. Ge, Y. Feng, N. Parry, S. Muthupalani, J. G. Fox, Cambridge, United Kingdom

W6.6 HC-NAP is a pro-atherogenic antigen produced by Helicobacter cinaedi Marina de Bernard, M. M. D’Elios, G. Codolo, Padua, Italy

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13:00 - 14:00 hrs Satellite Symposium - See page 22 for more information

14:00 - 15:00 hrs Lunch Break and Poster Rounds from Submitted Abstracts Poster Area Treatment of Helicobacter infection Chairpersons Group 1: Guenter Krejs, Varocha Mahachai

Chairpersons Group 2: Franco Bazzoli, Bojan Tepes Chairpersons Group 3: Marcis Leja, Tomica Milosavljevic

Chairpersons Group 4: David Graham, Joachim Labenz

Drug resistance and clinical issues Chairpersons: Javier Gisbert, Luiz Coelho

Inflammation, immunity, vaccines and host interaction Chairpersons: Steffen Backert, Michael Naumann

Helicobacter and extragastroduodenal disease Chairpersons: Anthony Axon, Theodore Rokkas

Gastric microbiota Gut microbiota in health and disease Chairpersons: Mirjana Rajilic-Stojanovic, Gianluca Ianiro

Gut microbiota and intestinal inflammatory disease

Gut microbiota and neoplastic diseases Gut microbiota modulation: antibiotics, probiotics, prebiotics and diet Gut microbiota colonization resistance and transplantation Chairpersons: Antonio Gasbarrini, Franco Scaldaferri

15:00 - 15:45 hrs Symposium Gut Microbiota in Cancer Main Hall Chairpersons: Tomica Milosavljevic, Massimo Rugge

Up to date on tumor immunology Jose C. Machado, Porto, Portugal (15’) Role of dysbiosis in colon carcinogenesis Georgina Hold, Aberdeen, United Kingdom (15’) Probiotics as adjuvant to cancer immunotherapy Mathias Chamaillard, Lille, France (15’)

15:45 - 16:30 hrs Plenary Workshop 3: Microbiota Main Hall Chairpersons: Deirdre McNamara, Paul Moayyedi

PW3.1 Transgenerational IBD in monoassociated H. saguini C57/129 IL10-/- mice A. Mannion, Z. Shen, D. Puglisi, S. Muthupalani, M. T. Whary, James G. Fox, Cambridge, MA, United States (10’) PW3.2 Effect of prior antibiotic exposure on colitis induced by Citrobacter rodentium Claire Roubaud Baudron, V. E. Ruiz, T. W. Battaglia, B. A. Vallance, G. I. Perez Perez, M. J. Blaser, Bordeaux, France (10’) PW3.3 Endoscopic peroral jejunal high-volume fecal microbiota transplantation Alexander Link, T. Lachmund, C. Schulz, J. Weigt, P. Malfertheiner, Magdebburg, Germany; (10’) PW3.4 Predictors of the need for repeated FMT in patients with recurrent C. difficile infection Gianluca Ianiro, L. Masucci, D. Nagel, G. Quaranta, R. Poto, F. Dibitetto, M. Gesualdo, F. D’aversa, F. Scalda-ferri, M. Sanguinetti, A. Gasbarrini, G. Cammarota, Rome, Italy (10’)


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17.00 - 17:30 hrs New Developments Main Hall Chairpersons: Franco Bazzoli, Richard Hunt

Aspirin, NSAIDs, NOACs and Helicobacter pylori Francis K. Chan, Shatin, Hong Kong (15’)

Microbiota and Viral Hepatitis C Gerardo Nardone, Naples, Italy (15’)

17:30 - 19:00 hrs Symposium: Treatment and Prevention of Gastric Cancer - Towards a Global Consensus Main Hall Chairpersons: Henry Cohen, Varocha Mahachai

Maastricht V: Key Messages in Treatment Javier Gisbert, Madrid, Spain (15’) Maastricht V: Key Messages in Prevention Strategies Anthony Axon, Leeds, United Kingdom (15’) The American Perspective The Canadian perspective: Sander Veldhuyzen van Zanten, CA (10’) The US perspective: David Graham, US (10’) The South American perspective: Luiz Coelho, BR (10’) The Asia-Pacific Perspective Noghua Lu, China (10’) Ken Sugano, Japan (10’)

Hwoong Y. Jung, Korea (10’)

19:00 - 19:15 hrs Awarding of the Marshall and Warren Medal to Ken Sugano Main Hall EHMSG Presentation and Poster Awards Presentation of the next meeting in Bordeaux, France Closing remarks

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EAGEN POSTGRADUATE COURSE - THURSDAy SEPTEMBER 15

EAGEN Postgraduate CourseGastrointestinal Microbiota in Health and Disease.

What is the current evidence?

Hotel Herrenkrug, Magdeburg, Festsaal, September 15, 2016Course Directors: P. Malfertheiner, A. Gasbarrini, F. Megraud

8.30 hrs Welcome and introduction to the course

8.35h - 9.55 hrs Gastrointestinal Microbiota in Health Chairpersons: Tamara Matysiak, France Emad El Omar, Australia

8.35h – 9.05 hrs Coevolution of gastrointestinal microbiota and the immune system - State of the art Martin Blaser, USA

9.05h – 9.20 hrs Gastrointestinal microbiota and the contribution to healthy aging - 3 key questions with voting

Mirjana Rajlic- Stojanovic, Serbia

9.20h - 9.30 hrs How to modulate an ideal microbiota consortium in the gut: the role of nutrition and lifestyle - 3 key questions with voting Alexander R. Moschen, Austria

9.30h - 9.40 hrs How to modulate an ideal microbiota consortium in the gut: the role of nutrition and lifestyle - Special comments Francesco Franceschi, Italy

9.40h – 9.55 hrs Questions & Answers

9.55h – 10.40 hrs Antibiotics and the Gut Microbiota Chairpersons: Jaroslaw Regula, Poland, Petr Dite, Czech Republic

9.55h – 10.10 hrs Selected case scenario - 3 key questions with voting Andreas Stallmach, Germany

10.10h - 10.20 hrs Antibiotics and the gut microbiota - Special comments Francis Mégraud, France

10.20h - 10.40 hrs Pro/Cons session on diverticular disease PRO: Tomica Milosavljevic, Serbia - CON: Lars Lundell, Sweden

10.40h – 11.00 hrs Break

11.00h – 13.00 hrs Gastrointestinal Microbiota in Disease Chairpersons: P. Malfertheiner, Germany S. Suerbaum, Germany F. Di Mario, Italy

11.00h - 11.15 hrs H. pylori and other gastric microbiota in gastroduodenal pathologies Emad El-Omar, Australia

11.15h - 11.25 hrs A case scenario patient with gastric cancer - 3 key questions with voting Christian Schulz, Germany

11.25h - 11.35 hrs H. pylori and other gastric microbiota in gastroduodenal pathologies – special comments Lars Engstrand, Sweden

11.35h - 11.50 hrs Gastrointestinal microbiota in the complexity of liver disease - 3 key questions with voting Antonio Gasbarrini, Italy

11.50h - 12.00 hrs Gastrointestinal microbiota in the complexity of liver disease – special comments Kerstin Schütte, Germany

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EAGEN POSTGRADUATE COURSE - THURSDAy SEPTEMBER 15

12.00h - 12.15 hrs Gastrointestinal microbiota in obesity and metabolic syndrome - 3 key questions with voting Piero Portincasa, Italy

12.15h - 12.25 hrs Gastrointestinal microbiota in obesity and metabolic syndrome – special comments Julia Mayerle, Germany

Moderation: Julia Mayerle, Germany12.25h - 12.45 hrs Special session: Bariatric surgery vs. medical therapy for the metabolic syndrome - impact on gut microbiota

Lars Lundell, Sweden 4 statements for interaction with audience

12.45h – 12.55 hrs Question & Answers

12.55h - 14.00 hrs Lunch

14.00h – 15.45 hrs 5 Messages for each TOPIC Chairpersons: Ernst Kuipers, Netherlands, Colm O’Morain, Ireland

14.00h – 14.15 hrs Gut microbiota and its role in allergic diseases Anne Mueller, Switzerland

14.15h – 14.30 hrs Gut microbiota in IBD Robert Haesler, Germany

14.30h – 14.45 hrs Gut microbiota and colon neoplasia Georgina L. Hold, UK

14.45h – 15.00 hrs Gut microbiota: Relentless progress in diagnostics Marius Vital, Germany

15:00h – 15.15 hrs Gut microbiota and psychiatric diseases Thomas Frodl, Germany

15.15h – 15.30 hrs Questions & Answers Session

15.30h – 15.45 hrs Break

15.45h – 16.30 hrs Gastrointestinal Microbiota as Therapeutic Principles Chairpersons: Günter Krejs, Austria, Tomica Milosavljevic, Serbia

15.45h – 16.05 hrs Probiotic bacterial species/strains: where is the evidence for efficacy – new trials Philippe Marteau, France

16.05h – 16.25 hrs Probiotic fungal therapy in clinical practice with presentation of algorithms Hania Szajewska, Poland

16.25h – 16.30 hrs Questions & Answers Session

16.30h – 17.00 hrs Meet the Professor in Round Table (both groups in main room) 1) Fecal microbiota transplantation: established indications and future views How to do?

Theodore Rokkas & Franco Scaldaferri & Alexander Link

2) Management of antibiotic resistance and the role of probiotics: H. pylori, MRSA, VRSE Francis Mégraud & Christian Schulz

Opening Ceremony in the Statdhalle Magdeburg18.00 – 19.00 Welcome reception

19.00 – 20.00 Welcoming addresses Peter Malfertheiner, President of the EHMSG Herrmann-Josef Rothkötter, Dean of the Medical Faculty

Magdeburg at the glance of history Gabriele Köster

Concert Julie Martin du Theil, soprano, Jovan Mitic, piano

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GENERAL INFORMATION

Corporate Satellites

Friday, September 16, 2016, 13:00 - 14:00 hrs - Main HallAllergan Satellite SymposiumWhat’s new in Helicobacter pylori eradication? The renaissance of bismuth

13:00 hrs Welcome and introduction Chair: Peter Malfertheiner, Germany

13:05 hrs Overcoming Helicobacter pylori antibiotic resistance in Europe with bismuth Francis Mégraud, France

13:20 hrs Update on management of Helicobacter pylori infection and the role of bismuth Franco Bazzoli, Italy

13:35 hrs Practical guidance on patient management with bismuth quadruple therapy • The spectrum from simple-to-treat to complex patients • Managing patient expectations Stephan Miehlke, Germany

13:55 hrs Panel discussion and close All

Lunch will be provided at this event

Peter MalfertheinerChair: Prof. Peter Malfertheiner Professor of Medicine and Chairman of the Department of Gastroenterology, Hepatology and Infectious Diseases at the Otto v. Guericke University of Magdeburg in Germany.

Francis MégraudProfessor of Bacteriology at the University of Bordeaux, Head of the Laboratory of Bacteriology at Hospital Pellegrin, Bordeaux, France and member of the INSERM U1053. He is the Head of the National Reference Center for Campylobacters & Helicobacters in France.

Stephan MiehlkeA gastroenterologist in private practice in Hamburg, Germany and an active participant in the German national guidelines on Helicobacter pylori in 2009 and 2016.

Franco BazzoliProfessor of Gastroenterology at the Faculty of Medicine & Research at the University of Bologna, Italy, and Director of the Gastroenterology and Endoscopy Unit and Department of Digestive Disease at university hospital Sant Orsola-Malpighi.

Saturday, September 17, 2016, 13:00 - 14:00 hrs - Main HallRICHEN Satellite SymposiumChina meets Europe in Helicobacter pylori infectionChairperson: A.Gasbarrini, Italy

13:00 hrs Gastric Cancer Prevention and Control: 33 years practice in Linqu County Wei-Cheng You, China

13:20 hrs H.pylori epidemiology in China Jian-Zhong Zhang, China

13:40 hrs H.pylori treatment in China Zhi-Qiang Song, China

RICHEN FORCE HOLDINGS

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GENERAL INFORMATION

Public Awareness Event - Magdeburg 2016Healthy Stomach Initiative - www.hsinitiative.org

When: September 16, 2016, 11.00h – 17.00 hrs September 17, 2016, 11.00h – 16.30 hrs

Where: in front of the main entrance of the congress venue (Magdeburg City Hall)

What: visit our stomach and step inside. Guided by Doctors of the Team of the University Hospital in Magdeburg under the coordination of U. v Arnim.

Friday, September 16, 2016 11.00 - 12.00 hrs R. Vasapolli

12.00 - 13.00 hrs J. Bornschein

13.00 - 14.00 hrs M. Selgrad

14.00 - 15.00 hrs E. Goni

15.00 - 17.00 hrs P. Malfertheiner & U. v. Arnim, AOK Health Insurance, Nutrition Specialists

Saturday, September 17, 2016 11.00 - 13.00 hrs U. v. Arnim & A. Link AOK Health Insurance, Nutrition Specialists

13.00 - 14.00 hrs C. Franck

14.00 - 15.00 hrs A. Hoffmann

15.00 – 16.30 hrs W. Obst

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GENERAL INFORMATION

Scientific Information, Talks

Oral Presentations

Commercial Disclosure information

Due to EACCME regulations, authors are requested to disclose possible conflicts of interest on the first slide.

A conflict of interest is any situation in which a speaker or immediate family members have interests, and those may cause a conflict with the current presentation. Conflicts of interest do not preclude the delivery of the talk, but should be explicitly declared. These may include financial interests (e.g. owning stocks of a related company, having received honoraria, consultancy fees), research interests (research support by grants or otherwise), organisational interests and gifts.If you have nothing to disclose, please state “I have no commercial disclosure” instead of the table.

Speaking TimeThe chairpersons of your session will be strict in allowing no more than the time allotted to your presentation. Remember to allow some time for the changeover of speakers and chairperson’s introduction, and for questions and discussion. Make yourself known to the chairpersons and/or the technician in your session room before the beginning of the session.

Projection and Technical SettingAll rooms are equipped with a (Windows) PC and data projector for Power Point presentation only.

Handing in your Presentation:It must then be handed over to the technician of the according lecture room in a break at least 1 hour before your talk either via USB drive (30 minutes for talks in the first morning sessions).

Presentation Format - Technical Issues:The lecture rooms are exclusively equipped with Windows-PCs (no Macintosh machines). Please bring a USB drive, formatted for Windows® (PC). You may want to carry a second disk or a USB-key as a back-up in case there is any technical problem.File Format: Microsoft® Power Point™ presentation formatted for Windows® (PC) only. (Operating system: Windows 10®). Optimised resolution: XGA (1024 x 768 pixel), ratio 4:3.

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Scientific Information, Poster Schedule

Poster Presentations

ATTENTION: Posters are on display for one day only. Posters need to be taken off by the author at the end of the day. Posters not removed until then will be removed by the staff. Posters will be discarded, and neither kept nor sent to the authors. Please note that the organisers cannot assume any liability for loss, theft or damage of posters displayed in the poster area.

You will find your poster board number in the author index of the abstract book, which you have received at the registration desk.

The presence at the poster of one of the authors is mandatory during the following times:

Friday, September 16, 2016, 14.00 - 15.00 hrs Diagnosis of Helicobacter infection• Epidemiology• Paediatrics• Virulence factors and pathogenesis of Helicobacter infection• Microbiology and genomics of Helicobacter• Gastric cancer and cancerogenesis•

Mounting of these posters in Rounds possible on Friday, September 16, 2016 from 8.00 - 10.00 hrs. Removal on Friday, September 16, 2016, from 17.00-19.00 hrs.

Saturday, September 17, 2016, 14.00 – 15.00 hrs Treatment of Helicobacter infection• Drug resistance and clinical issues• Inflammation, immunity, vaccines and host interaction• Helicobacter and extragastroduodenal disease• Gastric microbiota• Gut microbiota in health and disease• Gut microbiota and intestinal inflammatory disease• Gut microbiota and neoplastic diseases• Gut microbiota modulation: antibiotics, probiotics, prebiotics and diet• Gut microbiota colonization resistance and transplantation•

Mounting of these posters in Rounds possible on Saturday, September 17, 2016 from 8.00 - 10.00 hrs Removal on Saturday, September 17, 2016, from 17.00-19.00 hrs.

Please note that posters not removed by the indicated times, will be taken down by the staff of the conference centre and will not be stored or sent to the authors after the meeting.

FormatThe usable surface on the poster board is 90 cm width x 150 cm height (portrait format). Adhesive material will be made available.

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Acknowledgements

The organisers gratefully acknowledge the support of the following institutions and companies:

GOLD SPONSORS

RICHEN FORCE HOLDINGS

SILVER SPONSORS

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GENERAL INFORMATION

BRONZE SPONSORS

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GENERAL INFORMATION

In alphabetical order.

BadgesParticipants should collect name badges from the conference registration desk. As only registered participants will be permitted to attend the Scientific Sessions, the Exhibition and poster areas, you are kindly asked to wear your badge when entering the congress venue.

Cancellations and RefundsNotice of cancellation had to be made in writing by email or fax to the Congress Office.The policy for refunding registration fees is as follows:Written cancellation received:- Before August 12, 2016: 75% refund- After August 12, 2016: no refundThe date of the email or fax ID is the basis for considering refunds. Refunds will be made after the congress.

Certificate of AttendanceConfirmations of attendance will be issued at the registration desk.

Cash DispensersATMs are widely available in Magdeburg. Local currency (Euro) can also be obtained from banks and exchange bureaus.

CME Credits The “XXIXth International Workshop on Helicobacter and Related Bacteria in Chronic Digestive Inflammation and Gastric Cancer” was granted 12 European CME credits (ECMEC) by the European Accreditation Council for Continuing Medical Education (EACCME). The EAGEN Postgraduate Course “Gastrointestinal Microbiota in Health and Disease. What is the current evidence?” was granted 6 European CME credits (ECMEC) by the European Accreditation Council for Continuing Medical Education (EACCME).

Coffee Breaks and LunchDuring the session breaks refreshments (coffee, tea, and water) will be served free of charge to participants wearing name badges.Lunch tickets for Friday and Saturday had to be pre-ordered and cannot be purchased on site. Lunch tickets are not refundable.

Congress VenueXXIXth Workshop of the EHMSG:Stadthalle Magdeburg, Heinrich-Heine-Platz 1, 39114 Magdeburg, Germany

EAGEN Postgraduate Course:Hotel Herrenkrug - Festsaal, Herrenkrug 3, 39114 Magdeburg, Germany

How to reach the VenueClosest stops to the Stadthalle (tram or bus) are: Hesselbachplatz & ZollhausBus No 59 offers a few transfers from Hesselbachplatz to the Stadthalle. Walking distance from Hesselbachplatz or Zollhaus bus/tram stops to the Stadthalle is approx 15 minutes.

Currency The official currency of Germany is the Euro (EUR).1 EUR = 1,11 USD = 0,83 GBP = 103 JPY = 1,30 CHF = 11,41 SEK = 8,86 DKK = 1,32 AUD = 1,29 CADas per date of printing.

Electricity Supply230V - 50Hz; Sockets typ F. Connectors can be obtained from your hotel reception or electronic stores.

GSM cell phone roamingGSM cell/mobile phone roaming is available without any problems for all major international providers. It is advisable to inquire at your provider which roaming company in Germany offers the cheapest tarifs.

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GENERAL INFORMATION

InternetYou will find Internet cafés throughout the city. WIFI is available, please ask for a code at the registration desk.

LanguageThe official language of the congress is English (no simultaneous translation).

LiabilityIn registering for the EHMSG 2016 participants agree that neither the organising committee nor the congress office assume any liability whatsoever. Participants are requested to make their own arrangements in respect of health and travel. Furthermore, the organisers cannot assume any liability for changes in the programme due to external or unforeseen circumstances and force majeure.

Opening hours of the registration desk at the Congress Centre Thursday, September 15, 2016: 07.30 – 17.00 hrsFriday, September 16, 2016: 07.00 – 19.00 hrsSaturday, September 17, 2016: 07.45 – 19.15 hrs

Poster RemovalThe organisers cannot assume any liability for loss or damage of posters displayed in the poster area. Posters that were not removed after the end of the respective day of display, will be removed and will not be kept nor mailed to the author after the meeting.

PresentationsAll presenters should hand in their electronic presentation to the technician of the according lecture room in a break at least 1 hour before your talk either via USB-Memory Stick or DVD-Rom (30 minutes for talks in the first morning sessions).

Due to EACCME regulations, authors are requested to disclose possible conflicts of interest on the first slide.

A conflict of interest is any situation in which a speaker or immediate family members have interests, and those may cause a conflict with the current presentation. Conflicts of interest do not preclude the delivery of the talk, but should be explicitly declared. These may include financial interests (e.g. owning stocks of a related company, having received honoraria, consultancy fees), research interests (research support by grants or otherwise), organisational interests and gifts.If you have nothing to disclose, please state “I have no commercial disclosure” instead of the table.

Safety - CrimeVisitor safety is generally adequate, like in any other major European city. You can walk everywhere using common sense. Pick pocketing in heavily visited tourist zones or in public transport lines might be a concern.Unfortunately experience has shown that some basic precautionary measures should always be kept in mind in any city:- Do not carry important items like flight tickets, passports etc. with you when visiting the conference or strolling through the city, leave them in the hotel safe during your stay. Rather carry a Xerox copy of your passport or an identity card with you.- Try not to carry all documents, money, credit cards and other essential items and valuables in one bag. If it is lost or stolen, everything will be gone and might be difficult to replace on short notice, especially passports and visa to return to your country of residence.- Take off your name badge when leaving the conference venue, it will make you easily identifiable as a tourist.

Smoking PolicyThe EHMSG 2016 Workshop is a “No-smoking-Conference”.

StaffIf you should have any questions, the congress staff will be pleased to help you.

WeatherSeptember in Magdeburg• Average high: 20ºC / 68ºF• Average low: 10ºC / 50ºF• Average rainfall: 36 mm / 1,5• Rainy days: 8 • Hours of sun/day: 4,9

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Registration Details

Registration Fees Payment received Before July 15, 2016 After July 15, 2016 & on siteRegular Participants EUR 320.– EUR 420.–

Young Scientists (<35 years) EUR 170.– EUR 220.–

Students (< 30 years) EUR 110.– EUR 110.–

Company Representatives EUR 450.– EUR 550.–

EHMSG / EAGEN Postgraduate Course on September 15, 2016 EUR 100.– EUR 100.–

Combined Fee EHMSG 2016 & EAGEN Postgraduate Course - Regular Participants EUR 400.– EUR 500.–

Combined Fee EHMSG 2016 & EAGEN Postgraduate Course - Young Scientists under 35 EUR 250.– EUR 300.–

Combined Fee EHMSG 2016 & EAGEN Postgraduate Course - Young Scientists under 30 EUR 190.– EUR 190.–

Day Ticket - Regular / Young Scientist / Student - EUR 220.– / 145.– / 80.–

Networking Evening EUR 50.– EUR 50.–

Payment of Registration fees may be made either cash in Euro or by Credit Card (Diners Club, Mastercard and Visa).

Please note The reduced registration fee was only applicable, if it has been credited to the congress account before the deadline. Registering before July 15, 2016 without performing an actual payment was not sufficient to benefit from the reduction.

What is covered by the registration fee? • Admission to all scientific sessions and the exhibition• Admission to the networking mixer• Programme book• 1 copy of “Year in Helicobacter 2016 & Abstracts”• Refreshments during coffee breaks

Cancellations Notice of cancellation must have been made in writing by email or fax to the Congress Office. The date of the email/fax ID was the basis for considering refunds. Registration fees may be refunded after the workshop as follows. Cancellation received:- before August 12, 2016: 75% refund - after August 12, 2016: no refund

Networking Events

Thursday, September 15, 2016, 18.00 hrsEHMSG Networking Mixer & ConcertStadthalle Mageburg, Heinrich Heine Platz 1Free for registered participants, however registration for this event is mandatory.

Friday, September 16, 2016, 20.00 hrs EHMSG Networking Evening at the Jahrtausend TurmHerrenkrugstrasse 141, Entrance RosengartenPrice: EUR 50.-Ticket is required and will be checked at the entrance.

XXIXth International Workshop - Helicobacter · 2014 Manfred Kist, Freiburg, Germany 2013 Masahiro...

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