wyeth UBS Global Life Sciences Conference
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Transcript of wyeth UBS Global Life Sciences Conference
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WyethWyeth
UBS Global Life Sciences UBS Global Life Sciences ConferenceConference
Greg NordenSenior Vice President and Chief Financial Officer
September 25, 2007
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Forward-Looking Statement
The statements in this presentation that are not historical facts are forward-looking statements based on current expectations of future events and are subject to risks and uncertainties that could cause actual results to differ materially from those expressed or implied by such statements. These risks and uncertainties include risks associated with the inherent uncertainty of the timing and success of product research, development and commercialization (including with respect to the NDA filings for Wyeth’s pipeline products referenced in this presentation), drug pricing and payment for Wyeth’s products by government and third-party payers, manufacturing, data generated on the safety and efficacy of Wyeth’s products, the impact of competitive or generic products, trade buying patterns, global business operations, product liability and other types of litigation, the impact of legislation and regulatory compliance, intellectual property rights, strategic relationships with third parties, environmental liabilities, and other risks and uncertainties, including those detailed from time to time in Wyeth’s periodic reports filed with the Securities and Exchange Commission, including Wyeth’s current reports on Form 8-K, quarterly reports on Form 10-Q and annual reports on Form 10-K, particularly the discussion in Wyeth’s 2005 annual report on Form 10-K under the caption "Item 1A, Risk Factors." Wyeth assumes no obligation to publicly update any forward-looking statements, whether as a result of new information, future developments or otherwise.
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+12%+13%$1.84$0.90
Diluted Earnings Per Share
29%30%Tax Rate+20%+18%Operating Profit+10%+11%R&D Expense+2%+2%SG&A Expense
73.4%73.7%Gross Margin+10%+10%Net Revenue
YTD 20072Q 2007
*Adjusted to Exclude Certain Significant Items. See Press Release Issued July 19, 2007
Wyeth Performance: 2nd Quarter and Six Months 2007 - Key Financial Elements*
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4(in millions)
$0 $200 $400 $600 $800 $1,000 $1,200 $1,400
Rapamune
BMP-2
BeneFIX
Premarin
Zosyn
Alliance Rev.
Nutritionals
Protonix
Prevnar
Effexor
Enbrel
+3%
+17%
+19%
+25%
+22%
+7%
+22%
-1%
+3%
+4%
$1.3B
$977 M
$633 M
$550 M
$358 M
$355 M
$280 M
$267 M
$95 M
$89 M
$823 M (Amgen) $508 M (Wyeth)
$81 M -10%
Strong Performance In 2Q07
1st Half 2007 PharmaRevenue +11%
Marketed Products
Biotech Revenues +28%
in 1H07
Biotech Now Represents 37% of Total Pharma
Revenues
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2007 Guidance*
• Pro Forma EPS +11% to +13%• Revenue Growth Mid to High Single Digit• Gross Margin 72% to 74%• SG&A Increase at a Significantly Lower Rate than Revenue• R&D Growth Mid Single Digit• Tax Rate 27% to 29%
• Continue to Grow the Bottom Line at a Meaningfully Faster Rate Than Revenue Growth
Efforts Continue to Contain Cost Structure While Allowing Support of Key Brands and R&D
* Excludes Certain Significant Items
Raised Pro Forma EPS Guidance on 7/19/07 to $3.48 to $3.56
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2006 Wyeth’s Leadership Positions
#1 Antidepressant
#1 RA & Psoriasis Biologic
#1 Vaccine
#1 I.V. Antibiotic
#1 Infant Formula (In Markets Where We Compete)
#1 HT
#1 Hemophilia B
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Enbrel is One of the Ten Best-Selling Pharmaceutical Products in 13 Countries
Source: C&MI, IMS Midas Global Data MAT 2Q07
Countries Where Enbrel is Ranked In the Top Ten In Terms of Sales
(MAT 2Q07)
Enbrel is Ranked #1 in Sweden, Norway and Germany
Enbrel is Ranked in the Top 10 in:U.K. DenmarkGreece BelgiumLuxembourg SpainU.S. FinlandIreland Netherlands
Enbrel is Ranked #6 Globally and #4 In Europe
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Enbrel Japan
n Product Launch in March 2005 Under PMS Program
n PMS Enrollment Lifted April 2007 4Cumulative 14,000 Patients Enrolled
n Strong Revenue Growth in Japan in 200741H07 $56M (+75%)
42Q’07 $34M (+140%)
Expect Enbrel to Exceed $500 Million in Annual Sales in the Asia-Pacific Region
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+31%$1,249TOTAL
+24%69Asia Pacific
+118%94Latin America
+50%508EMEA
+13%$578United States
6National Programs Announced*
16Current National Programs
84Launched Countries
89Registered Countries
First Half 2007 Growth Current Status
Prevnar – Strong Global Growth
* Includes Ireland, Denmark, Cyprus, New Zealand, Costa Rica and Peru
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$3 B +
$1.5 B
$0
$1
$2
$3
$4
2005A 2009E
Sal
es (
$ B
illio
ns)
Source: Wyeth internal sales data, 2007
• New Launches• NIPs• Compliance/Catch-up• Emerging Markets
Double Sales by 2010 2009xxPrevnar – Growth Potential
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Total Market Potential
$6.0 B
Total Developed Market
Potential$2.5 B
Total Emerging/Developing
Potential$3.5 B
PrevnarPenetration:
4% (2006)
PrevnarPenetration:
73%(2006)
Prevnar 2006$2.0 B
Penetration:33%
Prevnar – Redefining The Possible
Emerging Markets
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Prevnar 13v – Expanding the Coverage
> $1.5 Billion> $3 BillionPeak Sales
n Proof of concept achieved
n Licensing criteria agreed upon
n Worldwide phase 3 studies ongoing
n Submission late 2009
n Phase 2 proof of concept achieved
n Licensing criteria agreed upon
n Worldwide phase 3 studiesongoing
n Submission early 2009
Status
Provide first and only conjugate vaccine that offers adults, age 50 and above, an opportunity to prevent pneumococcalpneumonia for the rest of their lives
Provide broadest coverage available for the global protection of children against pneumococcaldiseaseOpportunity
AdultInfant
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Wyeth’s Current/Near Term Opportunities
Prevnar 13v Adult
Prevnar 13v Infant
Methylnaltrexone (I.V.)
Aprela™
Menopausal Symptoms & Osteoporosis
Upcoming Upcoming SubmissionsSubmissions
Tygacil™(CAP)
ReFacto® AF
Methylnaltrexone (Subcutaneous)
Pristiq™
Depression
Viviant™
Osteoporosis Prevention & Treatment
Pending FDA Pending FDA ApprovalApproval
Torisel™
Lybrel™
Recent FDA Recent FDA ApprovalsApprovals
Tygacil™(HAP)
Bifeprunox
Pristiq™
Vasomotor Symptoms
Pending Pending Further TrialsFurther Trials
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BMP-2: Revolutionary Product Meeting Significant Medical Needs
n Approved in 37 Countries
n Used in ~300,000 Patients
n Oral Maxillofacial Procedures4 Approved by FDA in March 2007
n AMPLIFY for Posterolateral Spinal Fusion4 Submitted to and Accepted by FDA in Q1 2006
$0
$100
$200
$300
$400
$500
$600
$700
2003 2004 2005 2006
$ m
il + 102%
+ 41%
+ 30%
CAGR: ~50
%
INFUSE Sales(As Reported by Medtronic)2002:
Spinal Fusion
2004: Open Tibia
Fracture
Indications2007:
Oral Maxillofacial Procedures
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• Strong Revenue Growth in International Markets
• 2006: Global Nutrition $1.2B• 12% CAGR (’03-’06)
• Business Based on Science and Innovation
• Gold with Lutein• Medical Messaging
• Compelling Product Line / Markets
• 1st – 4th Age Segments• Specialty Products• Growing Markets
0
500
1,000
1,500
2003A 2004A 2005A 2006A 2007 1H
Asia Pacific EMEA
Latin America N America
$ Million
Source: Wyeth Finance
$705M
Wyeth Nutritionals Business Unit
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Notation: RegionNet Sales (2006A) Growth, ’06A vs ’05A
N America Sales not included
Asia Pacific$690M+ 23%
Europe /Middle East
$314M+ 3%
Latin America$193M+ 15%
2006 Net Revenue$1.2 Billion (+15%)
> 60 Countries
Wyeth Nutrition Global Presence (2006 Revenue)
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Wyeth Consumer Healthcare
n Wyeth Consumer Health - Solid Contributor to Revenue and Profit Growth at Wyeth4Worldwide Revenue +7% for 1st Half 2007
4Strong Worldwide Growth From Key Brands
4Strong International Growth- +16% in 1st Half 2007
Centrum®, Preparation H®, Caltrate® and Robitussin®
All Hold Number One Positions in Their Markets
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Driving Growth with Global BrandsModel for Success Yielding Growth, Driven by International
ANALGESICS
CENTRUM
CALTRATE +12%+8%$106 M
+22%+8%$327 M
+9%+8%$370 M
Int’l. % Growth
Global % Growth
YTD 6/30/07
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Wyeth’s Animal Health BusinessNet Sales 2004-2006
$0
$200
$400
$600
$800
$1,000
$1,200
2004 2005 2006
($ M
illio
ns)
5% 5%7%
$837 M $880 M $940 M
First Half 2007 Animal Health Net Revenue Was $554 Million (+6.5%)On Track to Exceed $1 Billion Mark in 2007
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n Offers Flea and Tick Protection for Dogs and Flea Protection for Cats
n European Approval 2006; U.S. Approval 2007n Largest Category in the Animal Health Market With
Global Annual Sales Exceeding $1.2 Billionn No Major New Product For Flea and Tick Protection in
Over Ten Yearsn Fort Dodge Animal Health Has Strong Position in the
U.S.A. Companion Animal Marketn ProMeris New Compound With Novel Mode of Actionn Expect ~$200 Million Third Full Year Sales
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Positioning Wyeth To Be A Stronger Company
n Wyeth Continues to Have a Strong Portfolio of Marketed Products and a Solid Pipeline of Potential Therapies
n We Are Confident in the Quality and Productivity of Our Research Organization and Our Ability to Bring New Products to Market.
n Wyeth Is a Financially Strong Company With Considerable Resources and We Will Continue to Improve Profitability by Enhancing Productivity
We Are Committed to Achieving Our Stated Goal of Delivering Solid Top Line Growth, Effectively Managing Costs, and Growing the Bottom Line at a Meaningfully
Faster Rate Than the Growth in Revenues