Second announcement

International conference: „Healthcare integrated biobanking and multiomics biomarker

analysis” (July 3-5, 2014)

Workshop: „Lipidomics for biomarker and clinical analysis” (July 1-3, 2014)

Dear Colleague,

We would like to announce the International Conference “Healthcare integrated biobanking and

multiomics biomarker analysis“ held in Regensburg during July 3-5, 2014

In addition, a pre-conference workshop on “Lipidomics for biomarker and clinical analysis” will take

place during July 1-3, 2014.

We would like to invite you to participate in our international events and visit the medieval city

Regensburg in Bavaria.

The goal of the conference is to transfer recent research and innovative biomarker candidates from

diverse body fluid- and cell-based analyses into applications for health-care integrated biobanking,

diagnostics, clinical practice, therapy-monitoring and outcome prediction. It covers

biomarker/biobanking aspects of multiomics analysis of a broad range of aging disorders such as

vascular diseases, “diabesity”, neurodegenerative diseases and inflammation.

The workshop will present lipidomic approaches to investigate body fluids, cells and tissues with a

focus on prealanytics, analytical strategies as well as data processing and visualization.

The conference and the workshop will bring together researchers, clinicians and industry to address the

latest developments in health care integrated biobanking and multiomics biomarker analysis.

In addition, the current status of the health-care integrated diagnostic and therapeutic biobank facility of

the Institute for Laboratory Medicine and Transfusion Medicine at the University Hospital Regensburg

will be presented.

For more information please visit the website www.multiomics.ukr.de

We are looking forward to meeting you in Regensburg in July 2014.

Prof. Schmitz and the organizing committee,

Evelyn Orsó, Gerhard Liebisch, Susanne Heimerl & Megi Sharikadze

H e a l t h c a r e

I n t e g r a t e d

B i o b a n k i n g

a n d

M u l t i o m i c s

B i o m a r k e r

A n a l y s i s

Regensburg, Germany

University Hospital Regensburg

End: July 5 , 2014

Start : Ju ly 3 , 2014

Second announcement

Registration For registration please visit the website of the conference and

follow the guidelines.

The registration fee covers the participation including lunches

and coffee breaks during the conference.

The conference follows the preconference workshop

„Lipidomics for Biomarker and Clinical Analysis” held in

Regensburg on July 1-3, 2014.

Contact:

Conference secretariat

Institute for Laboratory Medicine

and Transfusion Medicine,

University Hospital Regensburg

Franz-Josef-Strauß Allee 11,

D-93053 Regensburg, Germany

Phone: +49-941-944-6200/6201

Fax: +49-941-944-6202

E-mail: gerd.schmitz@ukr.de

For registration please consult

conference and workshop website

www.multiomics.ukr.de

Deadlines Early registration: April 1, 2014

Late registration: May 15, 2014

Abstract submission: May 15, 2014

International conference

Conference host The conference and the preconference workshop entitled

„Lipidomics for Biomarker and Clinical Analysis“ are

hosted by the Institute for Laboratory Medicine and Trans-

fusion Medicine at the University Hospital Regensburg.

http://www.ukr.de/kliniken-institute/klinische-

chemie/index.php

Conference venue Lecture Hall A2

University Hospital Regensburg

Franz-Josef-Strauß-Allee 11,

D-93053 Regensburg, Germany

Fees

Participant Early Late

Doctoral fellows 80 € 130 €

Postdocs (under 40) 100 € 150 €

Other researchers 150 € 200 €

Industry 300 € 350 €

Early registration ends on April 1, 2014.

Day 2: July 4, 2014 (continued)

Jens Wiltfang (Göttingen, Germany): Protein biomarkers in neurodegenerative diseases

Jochen Klucken (Erlangen, Germany): Alpha-synuclein and related proteins in the pathogenesis of Parkinson’s disease

Christoph H. Borchers (Victoria, Canada): MRM-based plas-ma proteomics in microbial infection and inflammation

Short presentations from abstracts

10:40 -11:00 Coffee break

11:00-12:55 S4: Membrane microdomains and

extracellular vesicles

Elina Ikonen (Helsinki, Finland): Membrane microdomains and vesicular traffic in cellular models of Alzheimer’s disease

Edit Buzás (Budapest, Hungary): Extracellular vesicles in in-flammation and autoimmunity

Anette Draeger (Bern, Switzerland): The “annexin-survival package”: plasma membrane repair and cellular damage control

Susanne Heimerl (Regensburg, Germany): Platelet-derived extracellular vesicles: implications to platelet transfusion and diseases

Short presentation from abstracts

13:00 -14:00 Lunch break

14:00-15:55 S5: Organelle lipidomics

Rudolf Zechner (Graz, Austria): Lipid droplets and diabesity

Evelyn Orsó (Regensburg, Germany): Endolysosomal lipids

and phospholipidosis

Michael Schlame (New York, USA): Endoplasmic reticulum and mitochondrial function in health and disease

Ronald J. A. Wanders (Amsterdam, The Netherlands): Peroxi-

somal function in health and disease

Short presentation from abstracts

15:55 -16:15 Refreshments

Heal thcare Integra ted Biobanking and Mul t iomics Biomarker Analysis (July 3 -5, 2014)

Conference program

Day 1: July 3, 2014

13:00 -13:10 Introduction

Gerd Schmitz (Regensburg, Germany)

13:10-15:15 S1: Health-care integrated biobanking

Thomas Illig (Hannover, Germany): Biobanking in multi-omics studies: lessons from cardiovascular diseases

Joachim Thiery (Leipzig, Germany): Biobanking and metabolomics from newborn screening to health-care

Michael Kiehntopf (Jena, Germany): Biobanking and tar-geted metabolomics for discrimination of systemic inflam-matory disorders in critically ill patients

Michael Neumaier (Mannheim, Germany): Cryostability of analytes in long term biobanking

Short presentation from abstracts

15:15 -15:45 Coffee break

15:45-17:55 S2: Transcriptomics and epigenetics

Assam El-Osta (Melbourne, Australia): Epigenetic implica-tions for the diabesity syndrome

Andrew J. Pospisilik (Freiburg, Germany): Epigenetic control by histone methylation

Antonio Moschetta (Bari, Italy): The oppprtunities and caveats of multigenic nuclear receptor regulation as therapeutic targets

Short presentations from abstracts

18:00-open end: Poster session with wine & cheese

Day 2: July 4, 2014

08:30-10:40 S3: Proteomics in civilization disorders

Helmut Meyer (Dortmund, Germany): Proteomic profiling differentiates hepatic steatosis, steatohepatitis and hepato-cellular carcinoma

Day 2: July 4, 2014 (continued)

16:15 -16:40 Keynote lecture: Gerd Schmitz

(Regensburg, Germany): High-density lipoproteins: from

reverse cholesterol transport to extracellular vesicle re-

lease and remodelling in vascular disease

19:00-open end: Gala-Dinner

Day 3: July 5, 2014

08:30-10:40 S6: Lipidomics in vascular and

metabolic diseases

Heribert Schunkert (Munich, Germany): Marker of vascu-lar and metabolic diseases: lessons from population ge-netics

Christian Wolfrum (Zürich, Switzer land): Major players of cellular lipid traffic in obesity: from mouse to man

Luigi Iuliano (Latina, Italy): Oxysterols and non-alcoholic fatty liver disease

Silke Matysik (Regensburg, Germany): Lipidomic “cascade” screening of plasma sterols: diagnostic stratifi-cation and therapeutic monitoring

Short presentations from abstracts

10:40 -11:00 Coffee break

11:00-13:00 S7: Cellular stress management

& lipotoxicity

Anna Nicolaou (Manchester, UK): Short-lived signalling lipids in inflammation

Ira J. Goldberg (New York, USA): Sphingolipids, lipotoxic cardiomyopathy and cardiac failure

Pablo V. Escribá (Palma de Mallorca, Spain): Lipid mi-crodomains, ER stress and autophagy in cancer cell ther-apy

Gábor Balogh (Szeged, Hungary): Lipids, as key players in cellular heat stress management

Short presentations from abstracts

13:00 Closing remarks

L i p i d o m i c s

f o r B i o m a r k e r

a n d C l i n i c a l

A n a l y s i s

Regensburg, Germany

University Hospital Regensburg

End: July 3 , 2014

Start : Ju ly 1 , 2014

Second announcement

Registration For registration please visit the website of the workshop and

follow the guidelines.

The registration fee covers the participation in the workshop

including lunches and coffee breaks during the workshop.

The number of the workshop participants is restricted up to

60 persons, therefore, to ensure your place at the workshop

you should register as soon as possible.

The workshop is followed by the conference „Healthcare

integrated biobanking and multiomics biomarker analy-

sis” held in Regensburg on July 3-5, 2014.

Contact:

Workshop secretariat

Institute for Laboratory Medicine

and Transfusion Medicine,

University Hospital Regensburg

Franz-Josef-Strauß Allee 11,

D-93053 Regensburg, Germany

Phone: +49-941-944-6200/6201

Fax: +49-941-944-6202

E-mail: gerd.schmitz@ukr.de

Pre-conference Workshop

Workshop host The workshop and the conference workshop entitled

„Healthcare integrated biobanking and multiomics bi-

omarker analysis“ are hosted by the Institute for Labora-

tory Medicine and Transfusion Medicine at the University

Hospital Regensburg.

http://www.ukr.de/kliniken-institute/klinische-

chemie/index.php

Workshop venue Seminar room A2 I-III

University Hospital Regensburg

Franz-Josef-Strauß-Allee 11,

D-93053 Regensburg, Germany

Fees

Participant Early Late

Doctoral fellows 130 € 180 €

Postdocs (under 40) 200 € 250 €

Other researcher 300 € 350 €

Industry 450 € 500 €

Early registration ends on April 1, 2014.

For registration please consult

conference and workshop website

www.multiomics.ukr.de

Workshop: L ip idomics for Biomarker and Cl in ica l Ana lysis

July 1 -3, 2014

Scope

This workshop will present cutting-edge knowledge on

Lipidomic analysis of body fluids, cells and tissues.

The focus will be on pre-analytical and analytical strate-

gies as well as on data processing and visualization.

Themes

The program includes several major topics such as

1. Membrane and trafficking lipids (glycerophospholipids,

sphingolipids, neutral lipids),

2. Signaling lipids (lysophospholipids, sphingolipids, eico-

sanoids, endocannabinoids, fatty acid amides, pros-

tanoids, oxysterols),

3. Analysis of body fluids and microparticles,

4. Analysis of cells and tissues,

5. Lipidomics in disease (e.g., endocrine disorders, stea-

totic liver disease).

Deadlines

Early registration: 1 April, 2014

Late registration: 15 May, 2014

Workshop speakers

Jos Brouwers (Utrecht, The Netherlands)

Uta Ceglarek (Leipzig, Germany)

Christer S. Ejsing (Odensee M, Denmark)

William J. Griffiths (Swansea, UK)

Michal Holčapek (Pardubice, Czech Republic)

Thomas Kopf (Regensburg, Germany)

Harald Köfeler (Graz, Austria)

Gerhard Liebisch (Regensburg, Germany)

Silke Matysik (Regensburg, Germany)

Robert C. Murphy (Denver, USA)

Toni Postle (Southampton, UK)

Manfred Rauh (Erlangen, Country)

Gerd Schmitz (Regensburg, Germany)

Andrej Shevchenko (Dresden, Germany)

Alexander Sigrüner (Regensburg, Germany)

Dimitrios Tsikas (Hannover, Germany)

Program outline

Day 1: 01.07.2014

12:00 - 13:00 Snacks and Registration

13.00 – 15.00 Session 1A. State of the art in lipidomics -

instrumentation, methods and data processing

15:00 – 15:30 Coffee break

15.30 – 17.30 Session 1B. State of the art in lipidomics -

instrumentation, methods and data processing

17:45 – 19.00: Discussion with beer and brezels: Current

and future concepts for instrumentation, methods and data

processing in lipidomics

Day 2: 02.07.2014

08.30 – 10.30 Session 2A. State of the art in eicosano-

ids and fatty acid analysis

10:30 – 11:00 Coffee break

11.00 – 12.30 Session 2B. State of the art in endocan-

nabinoids analysis

12:30 –13:30 Lunch break

13.30 – 15.00 Session 3A. State of the art in sterol and

oxysterol analysis

15:00 – 15:30 Coffee break

15.30 – 17.30 Session 3B. Steroid hormons

17:45 – 19.00: Discussion with beer and brezels: Preanaly-

tical issues: Pitfalls and solutions

Day 3: 03.07.2014

08.30 – 10.15 Session 4A. Clinical lipidomics

10:15 – 10:45 Coffee break

11.00 – 13.00 Session 4B. Perspectives - Discussion

12.25 – 12.30 Closing remarks