What could possibly go wrong? - E-Cigarette Summit 2019 · 2019/11/14 · Marijuana Alcohol Binge...
Transcript of What could possibly go wrong? - E-Cigarette Summit 2019 · 2019/11/14 · Marijuana Alcohol Binge...
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What could possibly go wrong?
Clive Bates
Counterfactual
E-cigarette Summit
14 November 2019
London
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Royal College of Physicians – unintended consequences
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…if a risk-averse, precautionary approach
makes e-cigarettes:
• less easily accessible
• less palatable or acceptable
• more expensive
• less consumer friendly
• pharmacologically less effective
• inhibits innovation …
…then it causes harm by perpetuating
smoking.
Royal College of Physicians – unintended consequences
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1.Banning the product
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Data from
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Applause for bans…
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European Union
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European Union smoking prevalence 2017
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European Union smoking prevalence 2017 - Sweden
Sweden
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Smoking Disease
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Finland – the prohibitionists should be paying attention
EU snus ban
Sweden diverges from Finland
Sweden
Finland
Maki J. The incentives created by a harm reduction approach to smoking cessation: Snus and smoking in Sweden and Finland. Int J Drug Policy. Netherlands; 17 June 2014;26(6):569–74
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Finland – the prohibitionists should be paying attention
EU snus ban
Norway converges with Finland Finland
Norway
Maki J. The incentives created by a harm reduction approach to smoking cessation: Snus and smoking in Sweden and Finland. Int J Drug Policy. Netherlands; 17 June 2014;26(6):569–74
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2. Protect the kids
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2. Being clueless about kids
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National Youth Tobacco Survey 2018 data
According to the findings, the number of U.S. high school students who reported being current e-cigarette users increased 78 percent between 2017 and 2018 to 3.05 million (or 20.8 percent).
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“Ban flavours”
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Drill down into the 2018 NYTS headline
20.8%
Percentage of high school students who used e-cigarettes in past 30 days
HEADLINE more than one
in five high school
students is vaping
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We can distinguish between frequent and infrequent use
Frequent use ≥20 days per
month
Infrequent use ≤ 19 days per
month
5.8%
15.0%
Most teen vapers (72%)
are not frequent users
Percentage of high school students who used e-cigarettes in past 30 days
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We can distinguish between prior tobacco users and never-users
5.3% 15.5%
Most teen vapers (75%)
are prior tobacco users
Percentage of high school students who used e-cigarettes in past 30 days
Prior tobacco use Never used tobacco
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We can segment by both frequency and prior tobacco use
Prior tobacco use Never used tobacco
Frequent use ≥20 days per
month
Infrequent use ≤ 19 days per
month
0.6% 5.2%
10.3% 4.7%
Few teen vapers (<3%)
are both tobacco naïve and frequent
users
Percentage of high school students who used e-cigarettes in past 30 days
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Anatomy of the 2018 NYTS headlines
Frequent use ≥20 days per
month
Infrequent use ≤ 19 days per
month
0.6% 5.2%
10.3% 4.7%
Most of the teen frequent vapers (90%)
are prior tobacco users – vaping may
be helping them
Percentage of high school students who used e-cigarettes in past 30 days
Prior tobacco use Never used tobacco
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Youth risk behaviors in context – United States 2017
0.0
5.0
10.0
15.0
20.0
25.0
30.0
35.0
E-cigarette Smoking anycombusible
tobacco
Marijuana Alcohol Bingedrinking
Drink driverriding as
passenger
Carried aweapon
Texting whiledriving
Perc
enta
ge o
f h
igh
sch
oo
l stu
den
ts
Past 30 day prevalence – high school students NYTS and YRBS
2019
2018
2017
Kann L, McManus T, Harris WA, et al. Youth Risk Behavior Surveillance — United States, 2017. MMWR Surveill Summ 2018;67(No. SS-8):1–114. * Refers to driver or passengers riding in vehicles where the driver had been drinking.
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Youth risk behaviours
During the 12 months before the survey:
• 7.4% had attempted suicide (23% LGBT)
• 2.4% of students had made a suicide attempt resulting in a serious harm
• 17.2% of students had seriously considered attempting suicide
• 19.0% had been bullied on school property
Kann L, McManus T, Harris WA, Shanklin SL, Flint KH, Queen B, et al. Youth Risk Behavior Surveillance — United States, 2017. MMWR Surveill Summ. 2018 Jun 15;67(8):1–114.
A nicotine-centric approach distracts from a person-centric approach
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3. Warnings
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Counter-productive requirement for cigarette-like warnings
This product contains
nicotine which is a highly
addictive substance. It is
not recommended for use
by non-smokers
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0% 2% 4% 6% 8% 10% 12% 14% 16% 18%
I do not want to substitute one addiction for another
I am not addicted to smoking and don't need help to quit
I do not know enough about them
I do not want to quit smoking
I do not think they would help me to quit or cut down
I am concerned they are not safe enough
Haven't got around to it yet
They cost too much
Other
I would be embarrassed to use them in public
I do not like the way they look
There are too many products to choose from
I’m using other things to help me quit smoking
They are too difficult to get hold of
Main reason for not trying an e-cigarette among smokers (2019)
Counter-productive requirement for cigarette-like warnings
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0% 2% 4% 6% 8% 10% 12% 14% 16% 18%
I do not want to substitute one addiction for another
I am not addicted to smoking and don't need help to quit
I do not know enough about them
I do not want to quit smoking
I do not think they would help me to quit or cut down
I am concerned they are not safe enough
Haven't got around to it yet
They cost too much
Other
I would be embarrassed to use them in public
I do not like the way they look
There are too many products to choose from
I’m using other things to help me quit smoking
They are too difficult to get hold of
Main reason for not trying an e-cigarette among smokers (2019)
Counter-productive requirement for cigarette-like warnings
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Research suggests a negative effect
“[Our findings] suggest that the
TPD nicotine addiction e-cigarette
health warning may reduce
smokers' willingness to use, and
likelihood of purchasing an e-
cigarette.”
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What would good consumer information look like?
This product is likely to be at least 95% safer
than smoking cigarettes
No product is completely safe, but use of this product is much less
harmful than smoking
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What would good consumer information look like?
1. If you are a smoker, switching completely to vaping is a much less harmful option.
2. While vaping products emit toxic substances, the amount is significantly lower
than in tobacco smoke.
3. By switching completely to vaping products, smokers are exposed to a small
fraction of the 7,000 chemicals found in tobacco smoke.
4. Switching completely from combustible tobacco cigarettes to e-cigarettes
significantly reduces users' exposure to numerous toxic and cancer-causing
substances.
5. Completely replacing your cigarette with a vaping product will significantly reduce
your exposure to numerous toxic and cancer causing substances.
6. Switching completely from smoking to e-cigarettes will reduce harms to your
health.
7. Completely replacing your cigarette with an e-cigarette will reduce harms to your
health.
Health Canada – proposed messages (not adopted)
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4. Ban advertising
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Banning advertising
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Does e-cigarette advertising encourage adult smokers to quit?
• E-cigarette advertising on TV causes adult smokers to quit.
• A ban on these ads would have reduced the number of smokers who quit by 3%.
• A more relaxed regulatory environment might have increased the quit rate by 10%.
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5. Limit nicotine strength
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Limit nicotine strength
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“I clearly don’t smoke cigarettes just because of
some kind of oral fixation”
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We need to talk about Juul and innovation
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The rise of Juul
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The rise of Juul
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Juul innovation to match cigarette
Acute Use of Nicotine Salt-based ENDS and Combusted Cigarettes Chris Wynne, M.D., Devonie S. Waaka, M.D. Christchurch Clinical Studies Trust, Ltd., NZ Gal Cohen, Ph.D., JUUL Labs, US. SRNT 2019 poster
Psychoactive experience Subjective experience
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We need to talk about Juul
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To summarise….
Few regulatory interventions so far are superior to…
… doing nothing
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Thankyou!
www.clivebates.com @clive_bates
Counterfactual