Parliamentary Standing Committee

June 14, 2017

Welcomes

NATIONAL INSTITUTE OF

PHARMACEUTICAL EDUCATION AND RESEARCH

(NIPER) S.A.S. NAGAR

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Vision of NIPER, S.A.S. Nagar

3

Formed as a society on Feb. 15, 1991,

under the aegis of

the Ministry of Chemicals and Fertilizers

Establishment of NIPER, S.A.S. Nagar

[Govt. of India Gazette Notification, 26.06.1998]

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Historical Perspective

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1991 Registered as a Society

1994 First Director and core faculty

joined

1996 Initiation of research activities

1998 NIPER Act: “Institute of

National Importance

Admission of first batch of

Masters’ students

2000 Dedication of NIPER to the

nation

2001 Visit of Joint Parliamentary

Committee

First Convocation

2003 Second Convocation:

Dr. A.P.J. Abdul Kalam,

Visitor and Chief Guest

2004 Establishment of National

Bioavailability Centre

2005 Establishment of National

Toxicology Centre

2007 Amendment of NIPER Act to

establish Six New NIPERs

2009 Establishment of Small and

Medium Pharmaceutical

Industry Centre

2016 ‘Silver Jubilee ‘ Year

6

Historical Perspective

Dedication of NIPER to the nation

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Governance at NIPER, S.A.S. Nagar

BOARD OF GOVERNORS Chairman: Eminent academician/scientist/

technologist/professional, to be nominated by

the Visitor

SENATE Chairman: Director, NIPER, S.A.S. Nagar

ACADEMIC PLANNING AND

DEVELOPMENT COMMITTEE

Chairman: Eminent academician/scientist/

technologist, to be nominated by the BoG

FINANCE COMMITTEE Chairman: Director, NIPER, S.A.S. Nagar

LABORATORY SERVICES,

BUILDING AND WORKS

COMMITTEE

Chairman: Director, NIPER, S.A.S. Nagar

BOARD OF STUDIES AND

RESEARCH

Chairman: Dean, NIPER, S.A.S. Nagar

DEPARTMENTAL ACADEMIC

ADVISORY COMMITTEE

Chairman: HoD of respective department

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BoG Director

Dean

• Academic Administration

• Examination

HoDs

• Academic Departments

Registrar

• Finance & Accounts

• Administration

• Purchase

• Maintenance

Administration at NIPER, S.A.S. Nagar

• Teaching activities

• Research activities

• Interaction with industry

Mandate, NIPER, S.A.S. Nagar

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HUMAN

RESOURCE

DEVELOPMENT

R&D

ACTIVITIES

Activities at NIPER, S.A.S. Nagar

Societal needs

Translational

Research

Industrial Support

Academics: Interdisciplinary Courses Medicinal Chemistry

Pharmaceutics

Natural Products

Traditional Medicine

Pharmacology & Toxicology

Regulatory Toxicology

Pharmaceutical Analysis

Biotechnology

Pharmaceutical Technology (Formulations)

Pharmaceutical Technology (Process Chemistry)

Pharmaceutical Technology (Biotechnology)

Pharmacy Practice

Clinical Research

Pharmacoinformatics

Pharmaceutical Management

Degrees Offered

• M. S. (Pharm.)

• M. Pharm.

• M. Tech. (Pharm.)

• M. B. A. (Pharm.)

• Ph. D.

DIS

CIP

LIN

ES

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12 12

Formulation Development

Approval & Marketing

Drug Discovery

Clinical Testing

(Phase I)

MEDICINAL CHEMISTRY

NATURAL PRODUCTS

BIOTECHNOLOGY

PHARMACOINFORMATICS

PHARMACOLOGY & TOXICOLOGY

PHARMACEUTICAL ANALYSIS

PHARMACOINFORMATICS

PHARMACEUTICAL TECHNOLOGY

PHARMACEUTICS

BIOTECHNOLOGY

PHARM. MANAGEMENT

PHARMACY PRACTICE

Pre-clinical Development

GREEN: STAGES OF DRUG DISCOVERY

BLACK: DEPARTMENTS

Academics: Drug discovery to market

NIPER

INDUSTRY

Earlier trend: R&D efforts in the pharma industry were taken care of by degree

holders in basic sciences

Current trend: With the graduates from NIPER, S.A.S. Nagar, R&D activities

are strengthened by trained manpower skilled in the nuances of

pharmaceutical sciences

Orientation of Academic

Programme at NIPER

All Masters’ and Ph.D. degrees at NIPER, S.A.S. Nagar, are research-based

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KNOWLEDGE

THRUST AREAS:

Neglected diseases

OTHER AREAS

Leishmaniasis (Kala Azar)

Tuberculosis

Formulation Development

Impurity Profiling

Pharmaceutical

Nanotechnology

Biopharmaceuticals

Proteomics

Functional Genomics

Pharmacoinformatics

Drug Discovery Drug Development

Malaria

Diabetes and other

lifestyle diseases

Research Areas

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Infrastructure at NIPER, S.A.S. Nagar

Library

Research and teaching blocks

Computer Centre 15

Infrastructure at NIPER, S.A.S. Nagar

Girls’ Hostel

Boys’ Hostel 16

Training of students at

NIPER, S.A.S. Nagar

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Training of students at

NIPER, S.A.S. Nagar

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Year PhD

2002 5

2003 17

2004 6

2005 16

2006 7

2007 5

2008 13

2009 11

2010 6

2011 29

2012 17

2013 26

2014 27

2015 25

2016-17** 50

TOTAL 260

Batch Masters’ MBA (Pharm.)

Dec 1999 27 -

Dec 2000 35 -

Dec 2001 37 -

Dec 2002 43 -

Dec 2003 55 -

July 2004* - 28

July 2005 67 29

July 2006 85 28

July 2007 87 19

July 2008 89 30

July 2009 99 34

July 2010 126 37

July 2011 147 43

July 2012 230 58

July 2013 232 52

July 2014 257 64

July 2015 167 28

July 2016 177 37

TOTAL 1960 487

HRD at NIPER, S.A.S. Nagar

* Semester system changed from 3 to 4. ** Till date

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Graduation of students at

NIPER, S.A.S. Nagar

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Output at NIPER, S.A.S. Nagar

Placement of graduating students is distributed over

• Academia (Doctoral and Postdoctoral positions)

• Academia (Teaching positions)

• Pharmaceutical industry (Domestic)

• Pharmaceutical industry (International)

• Regulatory bodies (Drug inspectors)

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Hospital

Pharmacy

Regulatory

Affairs Entrepreneurship

Medico-

Journalism

Quality

Control

Production

Career

Opportunities

Research &

Development Sales &

Marketing

Academics

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Some of our Recruiters

(Academic and Regulatory Agencies)

Our graduating students have been admitted to many top-

ranked institutes as PhD candidates, Post-doctoral Fellows

and as Faculty members

• IITs, IISERs, IISc

• TIFR, NCBS

• CSIR labs

• Universities in India

• Universities / Institutes in USA, Europe, Australia, New Zealand

Regulatory Agencies

• CDSCO

• USFDA

Some of our recruiters (Industry)

Output at NIPER, S.A.S. Nagar

Publicati

ons

Highest

impact

factor

Paten

ts

filed

Patents

granted

Patents

licensed

>2,100 40 182* 48* 07**

• Data till June 2017

• Includes some patents at different stages of filing and those granted to other

agencies as assignees

* Including foreign filings / approvals

** Including one patent which has been licensed to two US - based companies.

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Zinc Dispersible Tablets

NanoCrySP is a novel Spray

Drying Based method to

generate solid particles

containing drug nanocrystals

and small molecule excipients

Licensed to M/s Windlas Biotech Ltd.

Technology licensed out

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Technology licensed out

28

Central Instruments Laboratory

• Provides its analytical services to the industry, educational and

scientific research institutes across the country on pre-fixed

charges; 50% reduction for SMEs.

• A number of major equipment installed in various laboratories

at NIPER are made available for sample analysis to all outside

users. 29

National Toxicology Centre

• Acute Toxicity Study

• Sub- chronic Toxicity

Study

First GLP-certified laboratory in Government sector to

carry out pre-clinical toxicity testing of new chemical entities

(NCEs) for regulatory submission. 30

• Chronic Toxicity Study

• Sensitization Study

• Inhalation Study

National Bioavailability Centre

Approved for conducting bioavailability/bioequivalence studies

31

Technology Development Centre

• Develops economically viable processes for bulk

pharmaceutical chemicals of synthetic or natural products

origin, conventional and novel dosage forms.

• Experimental, pilot plant scale-up and validation, and

infrastructural facilities have been made available to

companies. 32

Analytical services provided to SMEs at 50% charges 29 seminars

107 hands-on trainings: 699 participants

Small & Medium Pharmaceutical

Industry Centre (SMPIC)

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Current Membership of SMPIC: 110

Skill development at SMPIC

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Centre for Pharmaceutical

Innovation & Entrepreneurship (CPIE)

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Outreach Programme at

NIPER, S.A.S. Nagar

Teachers and students from schools, colleges and universities 36

Outreach programme at

NIPER, S.A.S. Nagar

Training of drug regulatory personnel from Asian, African and East

European countries under Indian Technical and Economic Cooperation/

Special Commonwealth Assistance for Africa Programme [ITEC/SCAAP]

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Pharmaceutical Heritage Centre

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Publications, NIPER, S.A.S. Nagar

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Life on campus

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Life on campus

Other activities at NIPER, S.A.S. Nagar

Swachh Bharat Abhiyan Rashtriya Ekta Divas

Rajbhasha Award

National Technology Day 42

Amendment of NIPER Act

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Impact of NIPER, S.A.S. Nagar

S.A.S. Nagar

Raebareli

Hajipur

Kolkata

Guwahati

Hyderabad

Ahmedabad

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MHRD NIRF 2017 Rankings

(Category: Pharmacy)

Where do we stand vis-a-vis

other institutes?

NIPER S.A.S. Nagar achieved the second rank

46

Where do we stand vis-a-vis

other institutes? Degree

awarding

institute

Output

(100)

Impact

(100)

IP

(125)

Learning

(175)

Productivity

(50)

Total

(550)

AAAAA

IISc,

Bangalore

100.0 30.1 120.0 159.0 42.0 451.1

AAAA+

JNCASR,

Bangalore

24.0 46.1 79.0 150.0 50.0 349.1

TIFR,

Mumbai

47.3 59.5 71.0 146.0 18.1 341.9

NIPER,

Mohali

6.1 42.8 99.0 145.0 19.0 311.8

ICT,

Mumbai

19.4 26.6 71.5 145.0 45.0 307.4

[Data from Careers360 magazine, March 2014 issue]

47

Where do we stand vis-a-vis

other institutes?

Degree awarding

institute

Year of

establishment

AAAAA

IISc, Bangalore 1909

AAAA+

JNCASR, Bangalore 1989

TIFR, Mumbai 1945

NIPER, Mohali 1994

ICT, Mumbai 1933

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Where do we stand vis-a-vis

other institutes?

[Times of India, Chandigarh edition]

[09.03.2015]

Where do we stand vis-a-vis

other institutes?

NIPER, S.A.S. Nagar was awarded Thomson Reuters Innovation Award 2011 based

on

• The number of basic inventions published in the previous year

• The ratio of granted patents to basic inventions

• The global reach of the portfolio

• The overall influence of the portfolio as determined by international citations of

its research 49

Other recognitions Shanti Swaroop Bhatnagar Award

Ranbaxy Research Award

National Bioscience Award

JC Bose Fellowship

DBT Young Women Scientist Award

INSA Young Scientist Award

Distinguished Educator and Researcher Award (AAiPS)

IBM Faculty Award

OPPI Award

Chemical Research Society of India medal

Shakuntala Amir Chand Prize (ICMR)

Punjab Ratan Award

Advisor, WHO expert committee on specifications for pharmaceutical

preparations

Member, WHO Expert advisory panel on the International

Pharmacopoeia and Pharmaceutical Preparations

Innocentive Award

and others ...

Members, Fellows, National and International Science Academies 50

Medley Pharma-ceuticals Ltd.

Sun Pharmaceuticals Industries Ltd.

Biocon Ltd.

Wockhardt Ltd.

Panacea Biotec

Rajasthan Drugs and Pharmaceuticals Ltd.

Tirupati Medicare Dow Chemicals

MoUs with Industries (2015-2016)

52

Promotion and coordination of basic

and applied research in areas related

to pharmaceutical sectors

The economics of drug discovery process

prevents many small-scale entrepreneurs from

participation.

Provision of a platform containing common facilities to

scientists where the entire chain of drug discovery and

development process can be carried out without the

need for initial investment of capital budget.

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Promotion and coordination of basic

and applied research in areas related

to pharmaceutical sectors Solution to ‘Phase II’ attrition problem.

Establishment of R&D hub in the drug discovery and development

programme

Provision of soft loans to pharmaceutical industries to carry out R&D

activities with support of NIPER S.A.S. Nagar or to provide funds for

collaborative research between academia and industry

Industry should become a part of the R&D process right in the

beginning

Industry supported fellowship programmes as well as research

programmes of mutual interest

Inclusive participation of alumni in growth of Institute

Financial support from the DoP to set up an incubator research

facility for the pharmaceutical industry

54

Gross receipts (Rs. in lakh)

Year Sponsored

Projectsa

Sponsored

Consultancyb

2012-13 426.01 79.65

2013-14 247.95 94.77

2014-15 261.78 125.60

2015-16 336.23 134.94

2016-17 207.89 107.09

Working with external agencies

a From extramural funding agencies and industry b From industry

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Working with the industry

Company Project details

Alliance Formulations 3rd Generation synergistic

disinfectant

Cachet Pharma Anti snoring formulation

DSM Sinochem Amoxicillin and Clavulanic acid

tablets

Alliance Formulation Algard disinfectant formulation

DSM Sinochem Amoxicillin and Clavulanic acid

dry suspension

Promed (Sentiss) Ophthalmic formulation

AP Organics Oryznol capsule formulation

NIPER S.A.S. Nagar has carried out laboratory scale development of a

few formulations whether on their own or as sponsored projects from the

industry. Subsequently, the formulations were scaled up and

commercialized by the pharmaceutical industry. A few illustrative

instances are provided below:

Challenges being faced

• Shortage of faculty: Maintenance of optimal faculty-student

ratio.

• Release of funds under XII Plan approved by SFC.

- Approved: Rs. 249.455 cr

- Released: Rs. 9.79 cr only

• Urgent requirements:

(a) Replacement of old research equipment

(b) Creation of infrastructure like lecture halls, laboratories, etc.

(c) Maintenance of campus

• Short of Non-Plan funds every year

• Non-recognition of M.S. (Pharm.) degree by UGC has put

the career of many students at stake.

56

57

Emphasis in near future

Digital India

• E-Governance

• E-Tendering

• Electronic eye

Make in India

• Skill development and Startups

58

NIPER, SAS Nagar

is well equipped to meet

all the expectations of the country in

the field of Pharmaceutical Sciences

and Technology

We seek your

blessings and support

Thank you! 59