Volume 8, Number 4, July 2021Neurology.org/NN

A peer-reviewed clinical and translational neurology open access journal

ARTICLE

Updated Diagnostic Criteria for Paraneoplastic Neurologic Syndromes e1014

ARTICLE

Anti-CD20 Depletes Meningeal B Cells but Does Not Halt the Formation of Meningeal Ectopic Lymphoid Tissue e1012

ARTICLE

Allogeneic BK Virus-Specifi c T-Cell Treatment in 2 Patients With Progressive Multifocal Leukoencephalopathy e1020

VIEWS & REVIEWS

COVID-19 Among Patients With Multiple Sclerosis: A Systematic Review e1001

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A peer-reviewed clinical and translational neurology open access journal Neurology.org/NN

Neurology® Neuroimmunology & Neuroinflammation

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TABLE OF CONTENTS Volume 8, Number 4, July, 2021 Neurology.org/NN

Acknowledgment to Reviewers

e1002Neurology Neuroimmunology & Neuroinflammation’sAcknowledgment to Reviewers

Editorials

e1000Can Systemic Anti-CD20 BCell-Depleting AntibodiesEliminate Meningeal Follicles in MultipleSclerosis?S. Gupta and S.S. Zamvil

Open Access Article

e1015 The Pursuit of Precision in Paraneoplastic NeurologicDiseaseJ.R. Abbatemarco and S.L. Clardy

Open Access Article

Articles

e998 Tissue Transglutaminase Expression Associates WithProgression of Multiple SclerosisC. Sestito, C.E. Leurs, M.D. Steenwijk, J.J.P. Breve, J.W.R. Twisk,M.M.M. Wilhelmus, B. Drukarch, C.E. Teunissen,A.-M. van Dam, and J. Killestein

Open Access Article Class of Evidence

e997 Perturbed Microbiota/Immune Homeostasis inMultiple SclerosisD. Sterlin, M. Larsen, J. Fadlallah, C. Parizot, M. Vignes, G. Autaa,K. Dorgham, C. Juste, P. Lepage, J. Aboab, S. Vicart, E. Maillart,O. Gout, C. Lubetzki, R. Deschamps, C. Papeix, and G. Gorochov

Open Access Article

e999 Systemic Inflammation Is AssociatedWith NeurologicInvolvement in Pediatric InflammatoryMultisystem Syndrome Associated WithSARS-CoV-2M. Sa, L. Mirza, M. Carter, L. Carlton Jones, V. Gowda, J. Handforth,T. Hedderly, J. Kenny, K. Lascelles, J.-P. Lin, D. Lumsden,M. McDougall, O. Miller, T. Rossor, V. Shivamurthy, A. Siddiqui,R. Singh, S. Tang, M. White, S. Byrne, and M. Lim, on behalf of theEvelina PIMS-TS Study Group

Open Access Article

e1003 Serum Neurofilament Levels and PML Risk inPatients With Multiple Sclerosis Treated WithNatalizumabN. Fissolo, B. Pignolet, J. Rio, P. Vermersch, A. Ruet, J. deSeze,P. Labauge, S. Vukusic, C. Papeix, L. Martinez-Almoyna, A. Tourbah,P. Clavelou, T. Moreau, J. Pelletier, C. Lebrun-Frenay, B. Bourre,G. Defer, X. Montalban, D. Brassat, and M. Comabella

Open Access Article Class of Evidence

e1004 Exosomes From Subjects With Multiple SclerosisExpress EBV-Derived Proteins and ActivateMonocyte-Derived MacrophagesM.F. Mrad, E.S. Saba, L. Nakib, and S.J. Khoury

Open Access Article

e1008Use of Disease-Modifying Therapies in PediatricRelapsing-Remitting Multiple Sclerosis in theUnited KingdomO.A. Abdel-mannan, C. Manchoon, T. Rossor, J.-C. Southin, C. Tur,W. Brownlee, S. Byrne, M. Chitre, A. Coles, R. Forsyth, R. Kneen,K. Mankad, D. Ram, S. West, S. Wright, E. Wassmer, M. Lim,O. Ciccarelli, C. Hemingway, and Y. Hacohen, on behalf of theUK-Childhood Inflammatory Disease Network

Open Access Article

e1005 Kappa-Free Light Chains in CSF Predict EarlyMultiple Sclerosis Disease ActivityK. Berek, G. Bsteh, M. Auer, F. Di Pauli, A. Grams, D. Milosavljevic,P. Poskaite, C. Schnabl, S. Wurth, A. Zinganell, T. Berger, J. Walde,F. Deisenhammer, and H. Hegen

Open Access Article

e1006Network Damage Predicts Clinical Worsening inMultiple Sclerosis: A 6.4-Year StudyM.A. Rocca, P. Valsasina, A. Meani, E. Pagani, C. Cordani,C. Cervellin, and M. Filippi

Open Access Article

Cover ImageMyeloid cell markers expression and correlations between chemokinessecretion and cellular subsets: T-distributed stochastic neighborembedding (t-SNE) plots showing the distribution of different cellmarkers among monocytes and monocyte-derived macrophages(MDM). The upper right panel indicates day 1 for clusters ofmonocytes/before differentiation (pink) and day 7 for MDMs/ after differentiation(blue). The other panels show the distribution of expression intensities ofsingle markers CD45, CD11b, CD14, CD16 and CD68 on the cellularclusters in relation to time, day 1 and day 7. The color scale goes fromgreen (low) to red (high) fluorescence intensity. Plots are representativeof 12 different donors. Stylized by Haley McNiff, Digital Multimedia/Podcast Coordinator.See page e1004

Continued

e1007Gene-Environment Interactions in Multiple Sclerosis:A UK Biobank StudyB.M. Jacobs,A.J.Noyce, J.Bestwick,D.Belete,G.Giovannoni, andR.Dobson

Open Access Article

e1012 Anti-CD20 Depletes Meningeal B Cells but Does NotHalt the Formation of Meningeal EctopicLymphoid TissueR.M. Brand, V. Friedrich, J. Diddens, M. Pfaller,F. Romana de Franchis, H. Radbruch, B. Hemmer, K. Steiger, andK. Lehmann-Horn

Open Access Article Editorial, p. e1000

e1011 Inhibition of Maternal-to-Fetal Transfer of IgGAntibodies by FcRn Blockade in a Mouse Model ofArthrogryposis Multiplex CongenitaE. Coutinho, L. Jacobson, A. Shock, B. Smith, A. Vernon, and A. Vincent

Open Access Article

e1014Updated Diagnostic Criteria for ParaneoplasticNeurologic SyndromesF. Graus, A. Vogrig, S. Muñiz-Castrillo, J.-C.G. Antoine, V. Desestret,D. Dubey, B. Giometto, S.R. Irani, B. Joubert, F. Leypoldt, A.McKeon,H. Pruss, D. Psimaras, L. Thomas, M.J. Titulaer, C.A. Vedeler,J.J. Verschuuren, J. Dalmau, and J. Honnorat

Open Access Article Editorial, p. e1015

e1016 Long-term Follow-up andMuscle Imaging Findings inBrachio-Cervical Inflammatory MyopathyM. Lucchini, S. Bortolani, M. Monforte, M. Papacci, E. Ricci,M. Mirabella, and G. Tasca

Open Access Article

e1019 Autoimmune Global Amnesia as Manifestation ofAMPAR Encephalitis andNeuropathologic FindingsG. Ricken, T. Zrzavy, S.Macher, P. Altmann, J. Troger, K.K. Falk, A. Kiefer,A. Fichtenbaum, G. Mitulovic, H. Kubista, K.-P. Wandinger, P. Rommer,T. Bartsch, T. Berger, J. Weber, F. Leypoldt, and R. Hoftberger

Open Access Article

e1020 Allogeneic BK Virus-Specific T-Cell Treatment in 2Patients With Progressive MultifocalLeukoencephalopathyF. Hopfner, N. Mohn, B. Eiz-Vesper, B. Maecker-Kolhoff, J. Gottlieb,R. Blasczyk, N. Mahmoudi, K. Pars, O. Adams, M. Stangel,M.P. Wattjes, G. Hoglinger, and T. Skripuletz

Open Access Article Class of Evidence

e1018 Association of Retinal Layer Thickness WithCognition in Patients With Multiple SclerosisS.J. Baetge, M. Dietrich, M. Filser, A. Renner, N. Stute, M. Gasis,M. Weise, K. Lepka, J. Graf, N. Goebels, H.-P. Hartung, O. Aktas,S. Meuth, P. Albrecht, and I.-K. Penner

Open Access Article

Clinical/Scientific Notes

e993 Pembrolizumab-Associated CD8+ VasculiticMononeuritisMultiplex in aPatientWithMesotheliomaM.C. Baldauf,M. Kapauer,M. Joerger, L. Flatz, R. Rodriguez, S. Frank,A. Felbecker, S. Hartmann-Fussenegger, and T. Hundsberger

Open Access Article

e994 Imaging Features of Susac Syndrome onHigh-Resolution Intracranial Vessel Wall MRIN. Yahyavi-Firouz-Abadi, M. Kiczek, S.R. Zeiler, andB.A. Wasserman

Open Access Article

e996 Cytomegalovirus Encephalitis Under FingolimodMimicking Progressive MultifocalLeukoencephalopathy?D. Oel, K. Rigler-Hohenwarter, J. Trenkler, and R. Topakian

Open Access Article

e1009Delayed Benefit From AggressiveImmunotherapy in Waxing and WaningAnti-IgLON5 DiseaseP. Shambrook, A. Hesters, C. Marois, D. Zemba, J. Servan,B. Gaymard, F. Pico, C. Delorme, C. Lubetzki, I. Arnulf, D. Psimaras,J. Honnorat, A. Gales, and A. Meneret

Open Access Article Video

e1010 Anti-Adenylate Kinase 5 Encephalitis With HistologicEvidence of CNS VasculitisA. Vicino, V. Loser, P. Salvioni Chiabotti, J.P. Brouland, andR. Du Pasquier

Open Access Article

e1017 Aggressive Herpes Zoster in Young PatientsWith Multiple Sclerosis Under DimethylFumarate: Significance of CD8+ and NaturalKiller CellsM.C. Anagnostouli, G. Velonakis, and M.C. Dalakas

Open Access Article

e1021 Single-Dose Pembrolizumab Treatment forProgressive Multifocal LeukoencephalopathyM. Beudel, F. Rovekamp, D. van de Beek, and M. Brouwer

Open Access Article Class of Evidence

Views & Reviews

e1001COVID-19 Among Patients With Multiple Sclerosis:A Systematic ReviewM. Barzegar, O. Mirmosayyeb, M. Gajarzadeh, A. Afshari-Safavi,N. Nehzat, S. Vaheb, V. Shaygannejad, and A.-H. Maghzi

Open Access Article

Corrections

e1013Discontinuation of ImmunosuppressiveTherapy in Patients With NeuromyelitisOptica Spectrum Disorder With Aquaporin-4Antibodies

e1023 Systemic Inflammation Is Associated WithNeurologic Involvement in PediatricInflammatory Multisystem SyndromeAssociated With SARS-CoV-2

TABLE OF CONTENTS Volume 8, Number 4, July, 2021 Neurology.org/NN

2021;8; Neurol Neuroimmunol Neuroinflamm 8 (4)

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