Vol. 269, No. 14 The Journal of April 8, 1994 Biological Chemistry · 2001-06-27 · V 10378 10384...
Transcript of Vol. 269, No. 14 The Journal of April 8, 1994 Biological Chemistry · 2001-06-27 · V 10378 10384...
Vol. 269, No. 14 The Journal of April 8, 1994
Biological Chemistry Copyright 0 1994 by the American Society for Biochemistry and Molecular Biology, Inc.
428 East Preston St., Baltimore, MD 21202 U.S.A.
CONTENTS
10185
10189
10193
10197
10201
10205
10209
10213
10217
10221
10225
10229
10235
10242
10247
10252
MINIREVIEW Sorting of membrane proteins in the yeast secretory pathway. Steven F. Nothwehr and Tom H. Stevens
COMMUNICATIONS Differences between lumen targeting domains of chlo- roplast transit peptides determine pathway specificity for thylakoid transport. Ralph Henry, Aliki Kapazoglou, Michael McCaffery, and Kenneth Cline
A conditionally lethal yeast mutant blocked at the first step in glycosyl phosphatidylinositol anchor synthesis. Steven D. Leidich, Darren A. Drapp, and Peter Orlean
Macrophages adhere to glucose-modified basement membrane collagen IV via their scavenger receptors. Joseph El Khoury, Christian A. Thomas, John D. hike, Suzanne E. Hickman, Long Cao, and Samuel C. Silverstein
Cloning and characterization of cDNA encoding rat hemin-sensitive initiation factor-2a (eIF-Sa) kinase.
M. Flowers, Scot R. Kimball, and Leonard S. Jefferson Evidence for multitissue expression. Harry Mellor, Kevin
properties of Alzheimer amyloid protein analogues., Racemization of Asp” residue affects the aggregation
Takami Tomiyama, Satoshi Asano, Yoshiko Furiya, Takuy Shirasawa, Noriaki Endo, and Hiroshi Mori
Phospholipid-stimulated autophosphorylation acti- vates the G protein-coupled receptor kinase GRK5. Priya Kunupuli, Vsevolod V. Gurevich, and Jeffrey L. Benouic
Respective roles of glucose, fructose, and insulin in the regulation of the liver-specific pyruvate kinase gene promoter. Bruno Doiron, Marie-Heline Cuif, Axel Kahn, and Maria-Jose M. Diaz-Gwrro
Binding of G protein By-subunits to pleckstrin homol-
Pitcher, Gerry Shaw, and Robert J. Lefkowitz ogy domains. Kazushige Touhara, James Inglese, Julie A.
driven H+ translocation in uncoupled Q42E subunit c Suppressor mutations in F, subunit c recouple ATP-
Zhang, Mary Oldenburg, and Robert H. Fcllcngame mutant of Escherichia coli FIFo ATP synthase. Ying
DNA polymerase a overcomes an error-prone pause site in the presence of replication protein-A. Motoshi Suzuki, Shunji Izuta, and Shonen Yoshida
ARTICLES
pendent exocytosis from adrenal chromaffin cells. Ron- Evidence for the involvement of Rab3A in Caz+-de-
ald W. Holz, William H. Brondyk, Ruth A. Senter, Luzette Kuizon, and Ian G. Macara
Protein kinase A phosphorylation and G protein regu- lation of purified renal Na channels in planar bilayer
Dale J. Benos membranes. Iskander I. Ismailou, James H. McDuffie, and
tuted into liposomes acts as an iron transporter. The H+-ATPase from reticulocyte endosomes reconsti-
Cai- Yuan Li, J . Abra Watkins, and Jonathan Glass
Accessibility of the c-Src SH2-domain for binding is
Laudano, and David Shalloway increased during mitosis. Shubha Bagrodia, Andrew P.
promoter and its activation by the POU domain factor Characterization of an acetylcholine receptor a3 gene
SCIPjTst-1. Xiangdong Yang, Jennifer McDonough, Dmitry Fyodorov, Mark Morris, Feng Wang, and Evan S. Deneris
10265
10270
10280
10288
10298
10304
10312
10319
10324
10330
10341
10352
10357
10363
10370
The a/B subunit interaction in H+-ATPase (ATP syn- thase). An Escherichia coli a subunit mutation (Arg- a296 + Cys) restores coupling efficiency to the delete-
Mi- Yeon Park, Masatomo Maeda, and Masamitsu Futai rious B subunit mutant (Ser-B174 + Phe). Hiroshi Omote,
Staurosporine induces the cell surface expression of both forms of human tumor necrosis factor receptors on myeloid and epithelial cells and modulates ligand- induced cellular response. Lisha Zhang, Masahiro Higmhi, Klara Totpal, Madan M. Chaturvedi, and Bhurat B. Aggarwal
Luminal communication between intracellular calcium
Hajndczky, Chi Lin, and Andrew P. Thomas stores modulated by GTP and the cytoskeleton. Gyorgy
Localization of an apolipoprotein A-I epitope critical for lipoprotein-mediated cholesterol efflux from mon- ocytic cells. Carole L. Banka, Audrey S. Black, and Linda K. Curtiss
The influence of apolipoproteins on the structure and function of spheroidal, reconstituted high density lipo- proteins. Kerry-Anne Rye and Philip J . Barter
On the role of groES in the chaperonin-assisted folding
Buchner, Matthew J. Todd, George H. hrimer, and Paul V. reaction. Three case studies. Marion Schmidt, Johannes
Viitanen
Regulation of phosphoprotein p18 in leukemic cells.
By Xiang-Nong Luo, Bijoyesh Mmkerjee, Anna Ferrari, Cell cycle regulated phosphorylation by p34- kinase.
Sucharita Mistry, and George F. Atweh
Lipoprotein lipase domain function. Howard Wong, Rich- ard C. Davis, Tom Thuren, John W. Goers, Judith Nikazy, Moseley Waite, and Michael C. Schotz
Interaction of desacetamidocolchicine, a fast binding analogue of colchicine with isotypically pure tubulin dimers abn, a&, and ab^. Asok Banerjee, A n D’Hoore, and Yves Engelborghs
Developmental expression of trout egg polysialoglyco- proteins and the prerequisite a2,6-, and a2,8-sialyl and a2,8-polysialyltransferase activities required for their synthesis during oogenesis. Shinobu Kitazum, Ken Kita- jima, Sadako Inoue, Yasua Inoue, and Frederic A. Troy II
Identification of a novel determinant for basic domain- leucine zipper DNA binding activity in the acute-phase inducible nuclear factor-interleukin-6 transcription factor. Allan R. Brasier and Amalendra Kumar
Intracellular Mgl+ movement during muscarinic stim- ulation. M e uptake by the intracellular Cap+ store in rat sublingual mucous acini. Guo H. Zhang and James E. Melvin
Subtype-specific signaling mechanisms of somatostatin
and Diane L. Barber receptors SSTRl and SSTR2. Cuifen Hou, Robin L. Gilbert,
Phenotypic alterations in Fos-transgenic mice corre- late with changes in Fos/Jun-dependent collagenase type I expression. Regulation of mouse metalloprotein- ases by carcinogens, tumor promoters, CAMP, and Fos oncoprotein. Sabine Gack, Riidiger Vallon, Jorg Schoper, Ulrich Ruther, and Peter Angel
Mutational analysis of the traffic ATPase (ABC) trans- porters involved in uptake of eye pigment precursors in Drosophila melanogaater. Implications for struc- ture-function relationships. Gary D. Ewart, David Cannell, Graeme B. Cox, and Anthony J. Howells
* The CONTENTS arranged by Subject Categories will be found immediately following these CONTENTS. Full Instructions to Authors will be found in (1994) J. Biol. Chem. 269, 777-785, and reprints may be obtained from the editorial office.
t..
111
V
10378
10384
10393
10400
10407
10417
10423
0431
0438
0444
0451
10461
10467
10475
10485
10492
Expression in Escherichia coli of genes encoding the Ela and Elg subunits of the pyruvate dehydrogenase complex of Bacillus stearothermophilus and assembly
Lessard and Richard N. Perhum of a functional El component (ad.) in vitro. Ivan A. D.
The human chorionic somatomammotropin gene en- hancer is composed of multiple DNA elements that are
and Norman L. Eberhardt homologous to several SV40 enhansons. Shi- Wen Jiang
Molecular mechanism of regulation of yeast plasma membrane H+-ATPase by glucose. Interaction between domains and identification of new regulatory sites. Pilar Eraso and Francisco Portilh
The dephosphorylation reaction of the Ca*+-ATPase from plasma membranes. Claudia J . Herscher, Alcides F. Regs and Patricio J . Garrahun
Monoclonal antibodies FKl and WF6 define two neigh- boring ligand binding sites on Torpedo acetylcholine receptor u-polypeptide. Bernd Schnider, Sigrid Rein- hardt-Maelicke, Andre Schrattenholz, Kathryn E. McLane, Axel Kretschmer, Bianca M. Conti-Tronconi, and Alfred Maelicke
Functional independence of monomeric CHIP28 water channels revealed by expression of wild-type mutant heterodimers. Lan-bo Shi, William R. Skoch, and A. S. Verkman
Autocrine stimulation of the Xmrk receptor tyrosine kinase in Xiphophorus melanoma cells and identifica-
Malitschek, Joachim Wittbrodt, Petra Fischer, Reiner Lam- tion of a source for the physiological ligand. Barbara
mers, Axel UUrich, and Manfred Schartl
Cloning the structural gene for the 49-kDa form of exoenzyme S (exoS) from Pseudomoncrs aeruginosa
Mende-Mueller, Joseph T. Barbieri, and Dara W. Frank strain 388. Scott M. Kulich, Timothy L. Yahr, Liane M.
cDNA cloning and sequencing of mouse mastocytoma glucosaminyl N-deacetylase/N-sulfotransferase, an en-
Eriksson, Dagmr Sandbirck, Bo Ek, Ulf Lindahl, and Lena zyme involved in the biosynthesis of heparin. Znger
Kjefin
The third helix of the Antennapedia homeodomain translocates through biolo 'cal membranes. Daniek De- rossi, Aloin H. Joliot, Gerard phassaing, and A k i n Prochiantz
The sequences of human and bovine genes of the phos- phate carrier from mitochondria contain evidence of
Ferdinand0 Palmieri, and John E. Walker alternatively spliced forms. Vincenza Dolce, Vito Iacobazzi,
Functional a-tropomyosin produced in Escherichia coli. A dipeptide extension can substitute the amino-termi-
Lataro. Jesus Aparecido Ferro, and Fernando de Castro nal acetyl group. Patricia Brant Monteiro, Renata Crktina
Reinach
SH-PTP2/Syp SH2 domain binding specificity is de- fined by direct interactions with platelet-derived growth factor &receptor, epidermal growth factor receptor, and insulin receptor substrate-1-derived phosphopeptides. Randi D. Case, Elizabeth Piccione, Gert Wolf, Anton M. Benett, Robert J . Lechleider, Benjamin G. Neel, and Steven E. Shoelson
Roles of CCAAT/enhancer-binding protein and its binding site on repression and derepression of acetyl-
Ki-Han Kim CoA carboxylase gene. Hyi-Jeong Tae, Xiuochun L w , and
shrinkage is counteracted by an enhanced active trans- Response of human fibroblasts to hypertonic stress. Cell
Rossi, Ovidio Bussolati, and Gian C. Gazzolo port of neutral amino acids. Valeria Dall'Asta, Patrizia A.
Asymmetrical topology of diether- and tetraether-type polar lipids in membranes of Methanobacterium ther- moautotrophicum cells. Hiroyuki Morii and Yosuke Koga
10498
10504
10511
10517
10524
10529
10538
10545
10551
10559
10566
10574
10581
10590
10597
Identification of protein receptor for C~ostridium bot- ulinum type B neurotoxin in rat brain synaptosomes. Tei-ichi Nkhiki, Yoichi Kamta , Yasw Nemoto, Akira Omori, Tomoko Ito, Masami Takahashi, and Shunji Kozaki
Spectroscopic properties of desulfoferrodoxin from De- sulfovibrio desulfuricans (ATCC 27774). Pedro Tavares, Natarajan Ravi, Jose J . G. Moura, Jean LeGaU, Yun-Huo Huang, Brian R. Crouse, Michael K. Johnson, Boi Hanh Huynh, and Isabel Moura
Protein kinase C. mediates phospholipase D activation by nucleotides and phorbol ester in Madin-Darby ca- nine kidney cells. Stimulation of phospholipase D is independent of activation of polyphosphoinositide-spe-
Balboa, Bonnie L. Firestein, Catherine Godson, Kelly S. Bell, cific phospholipase C and phospholipase A*. Maria A.
and Paul A. Insel
Regulation of fluorescent fatty acid transfer from adi- pocyte and heart fatty acid binding proteins by acceptor membrane lipid composition and structure. Margo G. Wootan and Judith Storch
Multiple forms of the human tyrosine phosphatase
Gunter Daum, Stephan Regenass, Jan Sap, Joseph Schlessin- RPTPa. Isozymes and differences in glycosylation.
ger, and Edmond H. Fischer
Identification of phosphorylation sites in rat liver
MacDonald and Claudia Kent CTP:phosphocholine cytidylyltransferase. James I. S.
Microsomal retinoic acid metabolism. Effects of cellu- lar retinoic acid-binding protein (Type I) and C18- hydroxylation as an initial step. Paul D. Fiorella and Joseph L. Napoli
Identification of a vitamin D-responsive element in the 6'-flanking region of the rat 26-hydroxyvitamin Ds
Motoyuki Uchida, Toshimasa Shinki, Shigeaki Kato, Tatsw 24-hydroxylase gene. Yoshihiku Ohyama, Keiichi Ozono,
Suda, Osamu Yamamoto, Mitsuhide Noshiro, and Yukio Kat0
Modulation of transforming growth factor 6 receptors of rat lipocytes during the hepatic wound healing re- sponse. Enhanced binding and reduced gene expression
Scoff L. Friedman, Glenn Yamasaki, and Linda Wong accompany cellular activation in culture and in vivo.
Induction of dolichyl-saccharide intermediate biosyn- thesis corresponds to increased long chain cis-isopren- yltransferase activity during the mitogenic response in mouse B cells. Dean C. Crick, Jane R. Scocca, Jeffrey S. Rush, David W. Frank, Sharon S. Krag, and Charles J . Waechter
Divergence of genetic sequences for the vacuolating cytotoxin among Helicobacter pylori strains. Timothy L. Cover, Murali K. R. Tummuru, Ping Cao, Stuort A. Thomp- son, and Martin J. B h e r
Misfolded human chorionic gonadotropin @ subunits are secreted from transfected Chinese hamster ovary cells. Elliott Bedows, Sheila E. Norton, Jeffrey R. Huth, Nobuhiko Suganuma, Irving Boime, and Raymond W. Ruddon
Regulation by nerve growth factor and protein phos- phorylation of Na/K/2Cl cotransport and cell volume in PC12 cells. Sara h u n g , Martha E. O'Donnell, Anthony Mar- tinez, and H. Clive Palfrey
Isolation and characterization of a mutant dihydrofo- late reductase-thymidylate synthase from methotrex- ate-resistant Leishmania cells. Rosalia Arrebolo, Asuncion Olmo, Pedro Reche, Edward P. Garvey, Daniel V. Santi, Luis M. Ruiz-Perez, and Dolores Gonzalez-Pacanowskn
Selenophosphate synthetase. Enzyme properties and
D. Scholz, and Thressa C. Stadtman catalytic reaction. Zsuzsa Veres, Ick Young Kim, Thomas
The Journal of Biological Chemistry (ISSN 0021-9258) is published aeekly by the American Society for Biochemistry and Molecular B io lop Inc., 428 East Preston Street, Baltimore, MD 21202, U.S.A. Volume 269 for 1994: Institutions: United States, $790; Foreign, $980. Students/Post octoral Fellows: United States, $140; Foreign, $330. CD-ROM (available only with printed subscription): United States, $60; Foreign, $65. (Note: Maryland, Pennsylvania, and Canada add applicable taxes, unless a tax-exempt certificate number is shown.) The GST number for Canadian subscribers is 130369721. Second class postage paid at Baltimore, MD 21202, U.S.A. and at additional mailing offices. Printed in the U S A . P O S T M A S T E R Send address changes to THE JOURNAL OF BIOLOGICAL CHEMISTRY at 428 East Preston Street, Baltimore, MD 21202, U.S.A.
vi
10604
10609
10614
10621
10628
10637
10644
10651
10660
10668
10675
10683
10691
10699
10706
10713
10720
10729
Mutation of the two carboxyl-terminal tyrosines in the insulin receptor results in enhanced activation of mi- togen-activated protein kinase. Long Pang, Kim L. Milar- ski, Masa Ohmichi, Yasumitsu Takata, Jerrold M. Olefsky, and Alan R. Saltiel
Positively charged side chains in the insulin-like growth factor-1 C- and D-regions determine receptor binding specificity. Wengang Zhang, Thomas A. Gustafson, William J . Rutter, and Jeffrey D. Johnson
On the relationship between the mitochondrial inner membrane anion channel and the adenine nucleotide translocase. Mary F. Powers, Lisa L. Smith, and Andrew D. Beavis
Intestinal absorption of peptides by coupling to bile acids. Werner Kramer, Gunther Wess, Georg Neckermann, Gerrit Schubert, Jurgen Fink, Frank Girbig, Ulrike Gutjahr,
fons Enhsen, Eugen Falk, Michael Friedrich, Heiner Glombik, Simone Kowalewski, Karl-Heinz Baringhaus, Georg Boger, Al-
Axel Hoffmann, Christoph Pittius, and Matthios Urmann
The oligosaccharide binding specificities of CD22@, a
Ajit Varki sialic acid-specific lectin of B cells. Leland D. Powell and
Cytokine-induced &galactoside a-2,6-sialyltransfer-
of adhesion molecules and CD22 ligands. Kohji Hanosaki, ase in human endothelial cells mediates a2,6-sialylation
Ajit Varki, Ivan Stamenkouic, and Michael P. Bevilacqua
Factor X-activating glycoprotein of Russell's viper venom. Polype tide composition and characterization of the carbohytrate moieties. D. Channe Gowda, Craig M. Jackson, Preston Hensley, and Eugene A. Davidson
skeletal muscle troponin I gene. Shari J . Corin, Ondrej Structure and expression of the human slow twitch
Juhasz, Lei Zhu, Pam Conky, Larry Kedes, and Robert Wade
GATA-type zinc finger motif-containing sequences and chorion gene transcription factors of the silkworm Bombyx mori. J&l R. Dreuet, Yasir A. W. Skeiky, and Kostas Zatrou
platelet-derived growth factor-AA and a potent neu- Structural coincidence of aPDGFR epitopes binding to
tralizing monoclonal antibody. Jin-Chen Yu, Daruka Ma- hndeuan, William J . LaRochelle, Jacalyn H. Pierce, and Mo- h a m d A. Heidaran
Intermediate filament-like network formed in vitro by
Eeua-Liisa Nurmiaho-Lussila, and Mikael Rhen a bacterial coiled coil protein. Reini Hurme, Ellen Namork,
Cloning and expression of a novel acidic calponin iso-
Applegate, Waldo Feng, Robert S. Green, and Mark B. form from rat aortic vascular smooth muscle. Dianne
Taubman
I n vitro characterization of nonpeptide irreversible in- hibitors of HIV proteases. Rafael Salto, Lilia M. Babe, Jia Li, Jason R. Ros& Zhonghua Yu, Alma Burlingame, James J. De Voss, Zhihua Sui, Paul Ortiz de Montellano, and Charles S. Craik
The mouse y-glutamyl transpeptidase gene is tran- scribed from at least five separate promoters. Antonio R. Sepulueda, Bing Z. Carter, Geetha M. Habib, Russell M. Lebovitz, and Michael W. Lieberman
Clostridium difFicile toxin B acts on the GTP-binding protein Rho. Zngo Just, Gerhard Fritz, Klaus Aktories, Mu- rielle Giry, Michel R. P o p f f , Patrice Boquet, S i l k Hegenbarth, and Chrrstoph won Eichel-Stretber
High affinity interaction of dipteran high mobility group (HMG) proteins 1 with DNA is modulated by COOH-terminal regions flanking the HMG box domain. Jacek R. Wiiniewski and Ekkehard Schulze
rse, a novel receptor-type tyrosine kinase with homol- ogy to Axl/Ufo, is expressed at high levels in the br+ Melanie R. Mark, David T. Scadden, Zhengyu Wang, Qtmtn Gu, Audrey Goddard, and Paul J . Godowski
Autocrine regulation of rat chondrocyte proliferation by natriuretic peptide C and its receptor, natriuretic peptide receptor-B. Hiromi Hagiwara, Hajime Sakaguchi, Makoto Ztakura, Takanobu Yoshtmoto, Mayumi Furuya, Shoji Tanaka, and Shigehisa Hirose
10734
10739
10747
10753
10758
10764
10771
10776
10780
10790
10797
10804
10813
10820
10830
10838
10849
10856
10864
Shc is the predominant signaling molecule coupling insulin receptors to activation of guanine nucleotide releasing factor and p21"GTP formation. Toshiyasu
and JerroM M. Olefsky Sasaoka, Boris Draznin, J. Wayne Leitner, W. John Lunglois,
Reversible transcriptional activation of mdrl by so- dium butyrate treatment of human colon cancer cells.
Mary Jane Madden, and Kenneth H. Cowan Charles S. Morrow, Masayuki Nakagawa, Merrill E. Goldsmith,
Cytokines that associate with the signal transducer gp130 activate the interferon-induced transcription factor p 9 l by tyrosine phosphorylation. Gerald M. Feld- man, Emanuel F. Petricoin ZZZ, Michael David, Andrew C. Larner, and David S. Finbloom
Regulation of keratinocyte growth factor gene expres- sion by interleukin 1. Marcw Chedid, Jeffrey s. Rubin, Karl G. Csaky, and Stuart A. Aaronson
ent on both an ADP-ribosylation factor GTPase-acti- GTP hydrolysis by ADP-ribosylation factor is depend-
vating protein and acid phospholipids. Paul A. Randazzo and Richard A. Kahn
The cytoplasmic domain of myelin glycoprotein Po in- teracts with negatively charged phospholipid bilayers. Yungao Ding and Kurt R. Brunden
A mutational study of the C-terminal zinc-finger motif of the Escherichia coli UvrA protein. Jinting Wang, Kenneth L. Mueller, and Lawrence Grossman
Membrane cofactor protein (CD46) of complement. Processing differences related to alternatively spliced cytoplasmic domains. M. Kathryn Liszewski, Zndriati Tedja, and John P. Atkinson
Evidence that the cation occlusion domain of Na/K- ATPase consists of a complex of membrane-spanning segments. Analysis of limit membrane-embedded tryp- tic fragments. A h Shainskaya and Steven J. D. Karlish
A + U content rather than a particular nucleotide order
J . McDowall, Sue L i n - C b , and Stanley N . Cohen determines the specificity of RNase E cleavage. Kenneth
Effects of nucleotide sequence on the specificity of rne- dependent and RNase E-mediated cleavages of RNA I encoded by the pBR322 plasmid. Sue L i n - C b , Ten-Tsao Wong, Kenneth J . McDowaU, and Stanley N. Cohen
Remodeling of the transmembrane segment in human
Hung , Marion E. Reid, and Olga 0. Blumenfeld glycophorin by aberrant RNA splicing. Cheng-Han
Reciprocal interactions between protein kinase C and components of the NADPH oxidase complex may reg- ulate superoxide production by neutrophils stimulated with a phorbol ester. John T. Curnutte, Richard W. Erick- son, Jiabing Ding, and John A. Badwey
A novel transcriptional suppressor located within a downstream intron of the BCR gene. Mark J . Stewart, Gregory Cox, Anne Reifel-Miller, Su Young Kim, Carol A. Westbmk, and David S. Leibowitz
Retention and degradation of proteins containing an uncleaved glycosylphosphatidylinositol signal. Mark C. Field, Paul Moran, Wenlu Li, Gilbert-Andk Keller, and Ingrid W. Caras
Evidence that an &O-kDa mammalian plasma mem- brane protein with receptor-like properties mediates
perfringens enterotoxin. Ewa U. Wieckowski, Andrew P. the amphiphilicity of specifically bound Clostridium
Wnek, and Bruce A. McClane
Ranalexin. A novel antimicrobial peptide from bullfrog
bacterial antibiotic, polymyxin. Dough P. Clark, Stewart (Ram catesbeiam) skin, structurally related to the
Durell, W. Lee Maloy, and Michael Zasloff
Identification of a novel integrin binding site in fibro- nectin. Differential utilization by 83 integrins. Ron D. Bowditch, Meena Hariharan, Eiman F. Tominna, Jeffr W. Smith, Kenneth M. Yamoda, Elizabeth D. Getzoff, andgark H. Ginsberg
Identification and cellular localization of unique inter- feron mRNA from human placenta. Amy E. Whu.ley, C. s. Reddy Meka, Lisa A. Harbison, Joan S. Hunt, and Kazuhiko Imakawa
vii
10869 An altered specificity mutation in the X repressor in- duces global reorganization of the protein-DNA inter- face. James M. Benevides, Michael A. We&, and George J. Thomas, Jr.
10879 Specificity of coenzyme binding in thiamin diphos- phate-dependent enzymes. Crystal structures of yeast transketolase in complex with analogs of thiamin di- phosphate. Stephun Konig, Alfred Schellenberger, Holger Neef, and Gunter Schneider
10883 The crystal structure o succinyl-CoA synthetase from Escherichia coli at 2.5-1 resolution. William T. Wobdko, Marie E. Fraser, Michael N . G. James, and William A. Bridger
10891 Characterization of the chromosomal gene and pro- moter for human insulin-like growth factor binding protein-5. Susanne V. Allander, Cathurina Larsson, Ewa Ehrenborg, Adisak Suwanichkul, Gunther Weber, Sheila L. Morris, Svetlana Bajalica, Michnel C. Kiefer, Holger Luthmn, and David R. Powell
10899 On the role of the bithiazole moiety in sequence-selec- tive DNA cleavage by Fe-bleomycin. Stefanie A. Kane, Anand Natrajan, and Sidney M. Hecht
10905 Structure of the gene encoding the a subunit of the
factor receptor. Implications for the evolution of the human granulocyte-macrophage colony stimulating
shi Kosugi, Atsushi Miyajima, Ken-ichi Ami, and Takashi cytokine receptor superfamily. Yasushi Nakugawa, Hiro-
Yokota
10913 RNA/protein interactions in the 5”untranslated leader of HSP70 mRNA in Drosophila lysates. Lack of evi- dence for specific protein binding. Mark A. Hess and Roger F. Duncan
10923
10935
10940
10946
10956
10964
10965
10966
GENERAL INFORMATION
your s&cription agent or contact: THE JOURNAL OF BIOLOGICAL CHEMISTRY, This ublicatwn is availnble on CD-ROM. Inquire about availability through
428 EAST PRESTON STREET, BALTIMORE, MD 21202, U.S.A. Minireviews are reprinted in January of the succeeding year in a Minireview Compendium.
ASBMB Office, 9650 Rockville Pike, Bethesda, MD 20814, U.S.A. Compendia for 1988 through 1993 are auailnble through the ASBMB office:
Submit all manuscripts in triplicate to
9660 Rockville Pike Editor, The Journal of Biological Chemistry
Bethesda, MD 20814, U.S.A.
the autIor(s) will ay a charge per page. Current page charges may be ohtained Acce ted manuscripts will be published with the implicit understanding that
by contacting the QBC Office. Under exceptional circumstances, when no source
submission, for a grant-in-aid to Chairman, Publications Committee, Ameri- of grant or other support exists, the author(s) may apply, at the time of
can Society for Biochemistry and Molecular Biology, Inc., 9650 Rockville Pike, Bethesda, MD 20814. All such applications must be countersigned by an a propriate institutional official stating that no funds are available for page cRarges.
”Instructions to Authors, or of the “Editorial Policy and Practices,” or for Queries on matters of general editorial policy, requests for reprints of the
permission to reproduce any part of a previously ublished article should be directed to the Journal Editorial Office in Bethesfa, telephone 301-530-7150; fax 301-571-1824.
Reconstitution of complete SV40 DNA replication with purified replication factors. S h u Waga, Glenn Bauer, and Bruce Stillman
Angiotensin I1 stimulates tyrosine phosphorylation of phospholipase C-yl in vascular smooth muscle cells.
ford C. Berk, and Kenneth E. Bernstein Maria E . Marrero, William G. Paxton, Jennifer L. Dufi Brad-
the FLP recombinase with the FLP recognition target Interaction of the NH,- and COOH-terminal domains of
sequence. Gagan E . Panigrahi and Paul D. Sadowski
Alternative splicing governs sulfation of tyrosine or oligosaccharide on peptidylglycine a-amidating
and Betty A. Eipper monooxygenase. Hye-Young Yun, Henry T. Keutmnn,
Oncogenic activation of ~ 5 9 ” ” tyrosine protein kinase by mutation of its carboxyl-terminal site of tyrosine phosphorylation, tyrosine 528. Dominique Dauidson, Mar- ielle Fournel, and Andre Veillette
ADDITIONS AND CORRECTIONS
with monoclonal antibodies as probes. Does a renatured Unfolding/refolding studies on bovine &lactoglobulin
protein completely refold? Vol. 268 (1993) 22414- 22419. Makoto Hattori, Akw Ametani, Yoshinori Katakura, Makoto Shimizu, and Shuichi Kamimgawa
Inactivation of phytochrome- and phycobiliprotein- chromophore precursors by rat liver biliverdin reduc- tase. Vol. 268 (1993) 26099-26106. Matthew J . Terry, Mahin D. Maines, and J . Clark Lagarins
The active site substrate specificity of protein kinase C. Vol. 269 (1994) 4839-4844. Young-Guen Kwon, Mar- lanne Mendelow, and Davld S. Lawrence
topics of interest to biochemists. The views expressed are those of the authorb) The Journal of Biological Chemistry publishes papers on a broad range of
and not of The Journal of Biological Chemistry or the American Society for Biochemistry and Molecular Biology.
for Biochemistry and Molecular Biology, fnc. Reprographic copymg beyond The Journal of Biological Chemistry is co yrighted by the American Society
that permitted by Sections 107 or 108 of the US. Copyright Law is allowed, provided that the $2.50 per-copy fee is paid throu h the Copyright Clearance Center, 222 Rosewood Drive, Danvera, MA 01923. for those organlzntlons that have been granted photocopy license by CCC, a separate system of payment has been arranged. The fee code for users of the Transactional Reporting
Volume 254, Issue No. 1 (1979). Reproduction of any portlon of an article for Service is: 0021-9258/94/$2.50. @ Printed on acid-free paper effective with
subse uent republication requires permission of the copyright owner. Requests shoulEf be made in writing to the American Society for Biochemistry and Molecular Biology, Inc., Attn.: Editorial Office, 9650 Fbckville Pike, Bethesda, MD 20814, and should include a statement of intended use as well as explicit specifications of the material to be reproduced.
copies to: THE JOURNAL OF BIOLOGICAL CHEMISTRY, 428 EAST PRESTON Address all correspondence and orders relative to subscriptions and back
STREET, BALTIMORE, MD 21202, U.S.A., telephone 410-528-4255. Subscrip- tions are entered on a calendar year basis only. Requests for termination of subscriptions will be honored with proportional refunds less a $10 cancellation charge. Allow at least six weeks for address changes. Claims for replacement copies must be received within four months of the Issue date.
Vol. 269, No. 14
10185
*lo193
10288
10298
10330
10492
10628
10637
-10189
‘10197
-10213
10229
10247
10270
10280
10304
10357
The Journal of Biological Chemistry
CONTENTS Arranged by Subject Categories
April 8, 1994
MINIREVIEW
pathway. Steven F. Nothwehr and Tom H. Stevens Sorting of membrane proteins in the yeast secretory
CARBOHYDRATES, LIPIDS, AND OTHER NATURAL PRODUCTS
A conditionally lethal yeast mutant blocked at the first step in glycosyl phosphatidylinositol anchor synthesis. Steven D. Leidich, Darren A. Drapp, and Peter Orlean
Localization of an apolipoprotein A-I epitope critical
ocytic cells. Carole L. Bankn, Audrey S. Block, and Linda K. for lipoprotein-mediated cholesterol efflux from mon-
CurtLss
The influence of apolipoproteins on the structure and function of spheroidal, reconstituted high density lipo- proteins. Kerry-Anne Rye and Philip J . Barter
Developmental expression of trout egg polysialoglyco- proteins and the prerequisite a2,6-, and a2,8-sialyl and a2,8-polysialyltransferase activities required for their
jima, Sadako Imue, Yasua Imue, and Frederic A. Troy, I1 synthesis during oogenesis. Shimbu Kitazume, Ken Kita-
Asymmetrical topology of diether- and tetraether-type polar lipids in membranes of Methanobacterium ther- moautotrophicum cells. Hiroyuki Morii and Yosuke Koga
sialic acid-specific lectin of B cells. Leland D. Powell and The oligosaccharide binding specificities of CD228, a
Ajit Varki
Cytokine-induced &galactoside a-2,6-sialyltransfer- ase in human endothelial cells mediates a2,6-sialylation
Ajit Varki, Ivan Stamenkouic, and Michael P. Bevilocqua of adhesion molecules and CD22 ligands. Kohji Hanasaki,
CELL BIOLOGY AND METABOLISM Differences between lumen targeting domains of chlo- roplast transit peptides determine pathway specificity
Michael McCaffery, and Kenneth Cline for thylakoid transport. Ralph Henry, Aliki Kapazoglou,
Macrophages adhere to glucose-modified basement membrane collagen IV via their scavenger receptors. Joseph El Khoury, Christian A. Thomas, John D. h i k e , Suzanne E. Hickman, Long Cao, and Samuel C. Silverstein
Respective roles of glucose, fructose, and insulin in the regulation of the liver-specific pyruvate kinase gene promoter. Bruno Doiron, Marie-H6Dne Cuif, Axel Kahn, and Maria-Jose M. Dmz-Guerra
Evidence for the involvement of Rab3A in Cas+-de- pendent exocytosis from adrenal chromaffin cells. Ron- ald W. Holz, William H. Brondyk, Ruth A. Senter, Luzette Kuizon, and Ian G. Macara
Accessibility of the c-Src SH2-domain for binding is increased during mitosis. Shubha Bagrodia, Andrew P. Laudam, and David Shalloway
Staurosporine induces the cell surface expression of both forms of human tumor necrosis factor receptors on myeloid and epithelial cells and modulates ligand-
Klara Totpal, Madan M. Chaturuedi, and Bharat B. Aggarwal induced cellular response. Lisha Zhang, Masahiro Higuchi,
Luminal communication between intracellular calcium stores modulated by GTP and the cytoskeleton. Gyorgy Hajndczky, Chi Lin, and Andrew P. Thomas
On the role of groES in the chaperonin-assisted folding reaction. Three case studies. Marion Schmidt, Johannes Buchner, Matthew J. Todd, George H. Lorimer, and Paul V. Viitanen
Subtype-specific signaling mechanisms of somatostatin receptors SSTRl and SSTR2. Cuifen Hou, Robin L. Gilbert, and Dmne L. Barber
10363
10423
10467
10485
10498
10511
10529
10538
10551
10559
10604
10706
10729
10747
Phenotypic alterations in Fos-transgenic mice corre- late with changes in Fos/Jun-dependent collagenase type I expression. Regulation of mouse metalloprotein- ams by carcinogens, tumor promoters, CAMP, and Fos oncoprotein. Sabine Gack, Riidiger VaUon, Jorg Schaper, Ulrich Ruther, and Peter Angel
Autocrine stimulation of the Xmrk receptor tyrosine
tion of a source for the physiological ligand. Barbara kinase in Xiphophorus melanoma cells and identifica-
Malitschek, Joachim Wittbrodt, Petra Fischer, Reiner Lam- mers, Axel Ullrich, and Manfred Schurtl
SH-PTP2/Syp SH2 domain binding specificity is de- fined by direct interactions with platelet-derived
receptor, and insulin receptor substrate-1-derived growth factor &receptor, epidermal growth factor
phosphopeptides. Randi D. Case, Elizabeth Piccione, Gert
Neel, and Steven E. Shoelson Wol/, Anton M. Benett, Robert J . Lechleider, Benjamin G.
Response of human fibroblasts to hypertonic stress. Cell shrinkage is counteracted by an enhanced active trans- port of neutral amino acids. Valeria Dall’Asta, Patrizia A. Rossi, Ovidio Bussolati, and Gian C. Garzola
Identification of protein receptor for Clostridium bot- ulinum type B neurotoxin in rat brain synaptosomes. Tei-ichi Nishiki, Yoichi Kamata, Yasua Nemoto, Akira Omori, Tomoko Ito, Masami Takahnshi, and Shunji Kozaki
Protein kinase C, mediates phospholipase D activation by nucleotides and phorbol ester in Madin-Darby ca- nine kidney cells. Stimulation of phospholipase D is independent of activation of polyphosphoinositide-spe- cific phospholipase C and phospholipase An. Maria A. Balboa, Bonnie L. Firestein, Catherine Godson, Kelly S. Bell, and Paul A. Insel
Identification of phosphorylation sites in rat liver CTP:phosphocholine cytidylyltransferase. James I. S. MacDonuld and Claudia Kent
Microsomal retinoic acid metabolism. Effects of cellu- lar retinoic acid-binding protein (Type I) and C18-
Joseph L. Napoli hydroxylation as an initial step. Paul D. Fiorella and
Modulation of transforming growth factor @ receptors of rat lipocytes during the hepatic wound healing re- sponse. Enhanced binding and reduced gene expression accompany cellular activation in culture and in uiuo. Scott L. Friedman, Glenn Yamusaki, and Linda Wong
Induction of dolichyl-saccharide intermediate biosyn- thesis corresponds to increased long chain cis-isopren- yltransferase activity during the mitogenic response in mouse B cells. Dean C. Crick, Jane R. Scocca, Jeffrey S. Rush, David W. Frank, Sharon S. Krag, and Charles J . Waechter
Mutation of the two carboxyl-terminal tyrosines in the insulin receptor results in enhanced activation of mi- togen-activated protein kinase. Long Pang, Kim L. Milar-
Alan R. Saltlel ski, Masa Ohmichi, Yasumitsu Taknta, Jerrold M. Olefsky, and
Clostridium difficile toxin B acts on the GTP-binding protein Rho. Ingo Just, Gerhard Fritz, Klaus Aktories, Mu-
and Christoph won Eichel-Streiber rielle Giry, Michel R. Popoff, Patrice Boquet, Silke Hegenbarth,
Autocrine regulation of rat chondrocyte proliferation by natriuretic peptide C and its receptor, natriuretic peptide receptor-B. Hiromi Hagiwara, Hajime Sakoguchi,, Makoto Itakura, Taknmbu Yoshimoto, Mayumi Furuya, S ~ O J ~ Tanukn, and Shigehisa Hirose
Cytokines that associate with the signal transducer gp130 activate the interferon-induced transcription factor p91 by tyrosine phosphorylation. Gerald M. Feld- man, Emanuel F. Petricoin, I l l , Michael David, Andrew C. Lurner. and David S. Finbloom
Indicates a Communication viii
ix
10776
10830
10838
10935
-10209
10242
10378
10590
10597
10720
10758
10771
10813
10879
10956
10965
10966
'10221
Membrane cofactor protein (CD46) of complement. Processing differences related to alternatively s p l i c e cytoplasmic domains. M. Kathryn Lwewskr, Indrmti Tedla, and John P. Atkinson
Retention and degradation of proteins containing an uncleaved glycosylphosphatidylinositol signal. Mark C. Field, Paul Moran, Wenlu Li, Gilbert-Andre Keller, and Ingrid W. Caras Evidence that an =5O-kDa mammalian plasma mem- brane protein with receptor-like properties mediates
perfringens enterotoxin. Ewa U. Wieckowski, Andrew P. the amphiphilicity of specifically bound Clostridium
Wnek, and Bruce A. McClane
Angiotensin I1 stimulates tyrosine phosphorylation of phospholipase C-71 in vascular smooth muscle cells. Marw B. Marrero, William G. Paxton, Jennifer L. Duff, Brad- ford C. Berk, and Kenneth E. Bernstein
ENZYMOLOGY Phospholipid-stimulated autophosphorylation acti-
Priya Kunqpuli, Vsevolod V. Gurevich, and Jeffrey L. Benovic vates the G protein-coupled receptor kinase GRK5.
The H+-ATPase from reticulocyte endosomes reconsti- tuted into liposomes acts as an iron transporter. Cai-Yuan Li, J . Abra Watkins, and Jonathan Glass
Expression in Escherichia coli of genes encoding the Ela and El@ subunits of the pyruvate dehydrogenase complex of Bacillus stearothermophilus and assembly
Lessard and Richard N. Perham of a functional El component (a&) in vitro. Ivan A. D.
Isolation and characterization of a mutant dihydrofo- late reductase-thymidylate synthase from methotrex- ate-resistant Leishmania cells. Rosalia Arrebola, Asuncwn Olmo, Pedro Reche, Edward P. Garvey, Daniel V. Santi, Luis M. Ruiz-Perez, and Dolores Gonzalez-Pacanowska
Selenophosphate synthetase. Enzyme properties and catalytic reaction. Zsuzsa Veres, Ick Young Kim, Thomas D. Scholz, and Thressa C. Stadtman
rse, a novel receptor-type tyrosine kinase with homol- ogy to Axl/Ufo, is expressed at high levels in the brain. Melanie R. Mark, David T. Scadden, Zhengyu Wang, Qimin Gu, Audrey Goddard, and Paul J . Godowski
ent on both an ADP-ribosylation factor GTPase-acti- GTP hydrolysis by ADP-ribosylation factor is depend-
and Richard A. Kahn vating protein and acid phospholipids. Paul A. Randazzo
A mutational study of the C-terminal zinc-finger motif of the Escherichia coli UvrA protein. Jinting Wang, Kenneth L. Mwller, and Lawrence Grossman
Reciprocal interactions between protein kinase C and components of the NADPH oxidase complex may reg- ulate superoxide production by neutrophils stimulated
son, Jiubing Ding, and John A. Badwey with a phorbol ester. John T. Curnutte, Richard W. Erick-
phate-dependent enzymes. Crystal structures of yeast Specificity of coenzyme binding in thiamin diphos-
phosphate. Stephan Konig, Alfred Schellenberger, Holger transketolase in complex with analogs of thiamin di-
Neef, and Gunter Schneufer
Oncogenic activation of ~ 5 9 ~ " tyrosine protein kinase by mutation of its carboxyl-terminal site of tyrosine phosphorylation, tyrosine 528. Dominique Dauldson, Mar- ielle Fournel, and Andre Veillette
Inactivation of phytochrome- and phycobiliprotein- chromophore precursors by rat liver biliverdin reduc- tase. Vol. 268 (1993) 26099-26106. Matthew J . Terry, Mahin D. Maines, and J . Clark Lagarb
The active site substrate specificity of protein kinase C. Vol. 269 (1994) 4839-4844. Young-Gum Kwon, Mar- mnne Mendelow, and David s. Lawrence
MEMBRANES AND BIOENERGETICS Suppressor mutations in F1 subunit c recouple ATP- driven H+ translocation in uncoupled Q42E subunit c mutant of Escherichia coli FIFO ATP synthase. Ying Zhang, Mary Oldenburg, and Robert H. FiUingame
10235
10265
10352
10393
10400
10451
10581
10614
10621
10780
Protein kinase A phosphorylation and G protein regu- lation of purified renal Na channels in planar bilayer membranes. Iskander I. Ismailov, James H. McDufjSe, and Dale J . Benos The a/@ subunit interaction in H+-ATPase (ATP syn- thase). An Escherichia coli a subunit mutation (Arg- a296 + Cys) restores coupling efficiency to the delete-
Mi- Yeon Park, Masatomo Mae&, and Masamitsu Futai rious @ subunit mutant (Ser-,3174 Phe). Hiroshi Omote,
Intracellular MgP+ movement during muscarinic stim- ulation. MgP+ uptake by the intracellular Ca'+ store in
Melvin rat sublingual mucous acini. Guo H. Zhang and J a m s E.
Molecular mechanism of regulation of yeast plasma membrane H+-ATPase by glucose. Interaction between domains and identification of new regulatory sites. Pilar Eraso and Francisco Portillo
The dephosphorylation reaction of the Caa+-ATPase from plasma membranes. Claudw J . Herscher, Alcides F. Rega, and Patricw J. Garrahan The sequences of human and bovine genes of the phos- phate carrier from mitochondria contain evidence of alternatively spliced forms. Vincenza Doke, Vito Iacobazzi, Ferdinand0 Palmieri, and John E. Walker Regulation by nerve growth factor and protein phos- phorylation of Na/K/2CI cotransport and cell volume in PC12 cells. Sara Leung, Martha E. O'Donnell, Anthony Mar- tinez, and H. Clive Palfrey On the relationship between the mitochondrial inner membrane anion channel and the adenine nucleotide translocase. Mary F. Powers, Lisa L. Smith, and Andrew D. Beavis
Intestinal absorption of peptides by coupling to bile acids. Werner Kramer, Gunther Wess, Geog Neckermann, Gerrit Schubert, Jurgen Fink, Frank Girbig, Ulrike Gutjahr, Simone Kowalewski, Karl-Heinz Baringhaus, Geog Boger, Al- fons Enhsen, E en Falk, M+@l Friedrich, Heiner Glombik, Axel Hoffmnn,?hristoph Pzttlu, and Matthias Urmonn
Evidence that the cation occlusion domain of Na/K- ATPase consists of a complex of membrane-spanning segments. Analysis of limit membrane-embedded tryp- tic fragments. Aka Shainskaya and Steven J . D. Karlish
NUCLEIC ACIDS, PROTEIN SYNTHESIS, AND MOLECULAR GENETICS
-10201
010225
10252
10312
10384
10431
10475
10545
Cloning and characterization of cDNA encoding rat hemin-sensitive initiation factor-2a (eIF-2a) kinase. Evidence for multitissue expression. Harry Mellor, Kevin M. Flowers, Scot R. Kimball, and Leonard S. Jefferson
DNA polymerase a overcomes an error-prone pause site
Shunji Izuta, and S h n e n Yoshida in the presence of replication protein-A. Motoshi Swuki,
promoter and its activation by the POU domain factor Characterization of an acetylcholine receptor a3 gene
SCIP/Tst-1. Xiungdong Yang, Jennifer McDonough, Dmitry Fyodomv, Mark Morris, Feng Wang, and Evan S. Deneris Regulation of phosphoprotein p l 8 in leukemic cells. Cell cycle regulated phosphorylation by p34- kinase. By Xiang-Nong Luo, Bijoyesh Mookerjee, Anna Ferrari, Sucharita Mistry, and George F. Atweh
The human chorionic somatomammotropin gene en- hancer is composed of multiple DNA elements that are homologous to several SV40 enhansons. Shi- Wen Jiang and Norman L. Eberhardt
exoenzyme S (exoS) from Pseudomonas aemginosa Cloning the structural gene for the 49-kDa form of
Mende-Mueller, Joseph T. Barbieri, and Dara W. Frank strain 388. Scott M. Kulich, Timothy L. Yahr, Liane M.
binding site on repression and derepression of acetyl- Roles of CCAAT/enhancer-binding protein and its
Ki-Han Kim CoA carboxylase gene. Hyi-Jeong Tae, Xiaochun Luo, and
Identification of a vitamin D-responsive element in the 5"flanking region of the rat 25-hydroxyvitamin Ds 24-hydroxylase gene. Yoshihiko Oh ama, Keiichi Ozono, Motoyuki Uchida, Toshimasa Shinki, ihigeaki Kato, Tatsuo Suda, Osamu Yamumoto, Mitsuhide Noshim, and Yukw Kat0
Indicates a Communication
X
10566
10651
10660
10699
10713
10739
10753
10790
10797
10804
10820
10864
10869
10891
10899
10905
10913
10923
Divergence of genetic sequences for the vacuolating cytotoxin among Helicobacter pylori strains. Timothy L. Cover, Murali K. R. Tummuru, Ping Cao, Stuart A. Thomp- son, and Martin J . Blaser
Structure and expression of the human slow twitch
J u h z , Lei Zhu, Pam Conky, Larry Kedes, and Robert Wade skeletal muscle troponin I gene. Shuri J. Corin, Ondrej
GATA-type zinc finger motif-containing sequences and
Bombyx mori. Joel R. Drevet, Yasir A. W. Skeiky, and chorion gene transcription factors of the silkworm
Kostas Iatrou
scribed from a t least five separate promoters. Antonia The mouse y-glutamyl transpeptidase gene is tran-
Lebovitz, and Michael W. Lieberman R. Sepulveda, Bing Z. Carter, Geethu M. Habib, Russell M.
High affinity interaction of dipteran high mobility group (HMG) proteins 1 with DNA is modulated by COOH-terminal regions flanking the HMG box domain. Jacek R. Wiiniewski and Ekkehurd Schulze
Reversible transcriptional activation of m d r l by so- dium butyrate treatment of human colon cancer cells.
Mary Jane Mada'en, and Kenneth H. Cowan Churles S. Morrow, Masayuki Nakagawa, Merrill E. Goldsmith,
Regulation of keratinocyte growth factor gene expres- sion by interleukin 1. Marcio Chedid, Jeffrey s. Rubin, Karl G. Csaky, and Stuart A. Aaronson
A + U content rather than a particular nucleotide order
J . McDowall, Sue Lin-Chao, and Stanley N. Cohen determines the specificity of RNase E cleavage. Kenneth
Effects of nucleotide sequence on the specificity of me-
encoded by the pBR322 plasmid. Sue Lin-Chao, Ten-Tsao dependent and RNase E-mediated cleavages of RNA I
Wong, Kenneth J . McDowaU, and Stanley N. Cohen
Remodeling of the transmembrane segment in human glycophorin by aberrant RNA splicing. Cheng-Han Huang, Marion E. Reid, and Olga 0. BlumenfeM
A novel transcriptional suppressor located within a downstream intron of the BCR gene. Mark J . Stewart, Gregory Cox, Anne Reifel-Miller, Su Young Kim, Carol A. Westbrook, and David S. Leibowib
Identification and cellular localization of unique inter-
Reddy Meka, Lisa A. Harbison, Joan s. Hunt, and Kozuhiko feron mRNA from human placenta. Amy E. Whuley, C. S.
Imakawa
An altered specificity mutation in the A repressor in- duces global reorganization of the protein-DNA inter- face. James M. Benevides, Michael A. Weiss, and George J . Thomas, Jr.
Characterization of the chromosomal gene and pro- moter for human insulin-like growth factor binding protein-6. Susanne V. Allander, Cathurina Larsson, Ewa Ehrenborg, Adisak Suwanichkul, Gunther Weber, Sheila L. Morris, Svetlana Bajalica, Michael C. Kiefer, Holger Luthman, and David R. Powell
On the role of the bithiazole moiety in sequence-selec- tive DNA cleavage b,y Fe-bleomycin. Stefanie A. Kane, Anand Natra~an, and Sulney M. Hecht
Structure of the gene encoding the a subunit of the human granulocyte-macrophage colony stimulating
cytokine receptor superfamily. Yasushi Nakagawa, Hiro- factor receptor. Implications for the evolution of the
shi Kosugi, Atsushi Miyajimn, Ken-ichi Arai, and Takmhi Yokota
RNA/protein interactions in the 6'-untranslated leader of HSP70 mRNA in Drosophila lysates. Lack of evi-
F. Duncan dence for specific protein binding. Mark A. Hess and Roger
Reconstitution of complete SV40 DNA replication with purified replication factors. Shou Woga, Glenn Bauer, and Bruce Stillman
10940
'10205
-10217
10319
10324
10341
10370
10407
10417
10438
10444
10461
10504
10517
10524
10574
10609
10644
Interaction of the NHn- and COOH-terminal domains of the FLP recombinase with the FLP recognition target sequence. Gagan B. Panigrahi and Paul D. Sadowski
PROTEIN CHEMISTRY AND STRUCTURE Racemization of AspPS residue affects the aggregation properties of Alzheimer amyloid @ protein analogues.
Shirasawa, Noriaki Endo, and Hiroshi Mori Takami Tomiyama, Satoshi Asano, Yoshiko Furiya, Takuji
Binding of G protein @?-subunits to pleckstrin homol- ogy domains. Kazushige Touhura, James Inglese, Julie A. Pitcher, Gerry S h w , and Robert J. Lefkowitz
Lip0 rotein lipase domain function. Howard Wong, Rich- ard 8 Dave, Tom Thuren, John W. Goers, Judith Nikazy, Moseky Warte, and Michael C. Schotz
Interaction of desacetamidocolchicine, a fast binding analogue of colchicine with isotypically pure tubulin dimers a h , a@=. and a&. Asok Banerjee, A n D'Hoore, and Yves Engelborghs
Identification of a novel determinant for basic domain- leucine zipper DNA binding activity in the acute-phase inducible nuclear factor-interleukin-6 transcription factor. Allan R. Brasier and Amalendra Kumar
Mutational analysis of the traffic ATPase (ABC) trans- porters involved in uptake of eye pigment precursors in Drosophila melanogaeter. Implications for struc- ture-function relationships. Gary D. Ewart, David Cannell, Graeme B. Cox, and Anthony J . Howelk
boring ligand binding sites on Torpedo acetylcholine Monoclonal antibodies FK1 and WF6 define two neigh-
receptor a-polypeptide. Bernd Schroder, Sigrid Rein-
Axel Kretschmer, Bianca M. Conti-Tronconi, and Alfred hurdt-Maelicke, Andre Schrattenholz, Kathryn E. McLane,
Maelicke
Functional independence of monomeric CHIP28 water channels revealed by expression of wild-type mutant heterodimers. Lan-bo Shi, William R. Skoch, and A. S. Verkman
cDNA cloning and sequencing of mouse mastocytoma glucosaminyl N-deacetylase/N-sulfotransferase, an en-
Eriksson, Dagmar Sandbick, Bo Ek, Ulf Lindahl, and Lena zyme involved in the biosynthesis of heparin. Inger
Kjelkn
The third helix of the Antennapedia homeodomain translocates through biological membranes. Daniele De- rossi, Alain H. Joliot, Gerard Chnssaing, and Alain Prochiantz
Functional a-tropomyosin produced in Escherichia coli. A dipeptide extension can substitute the amino-termi- nal acetyl group. Patricia Brant Monteiro, Renata Cristina Lataro, Jesus Aparecido Ferro, and Fernando de Castro R e i m h
Spectroscopic properties of desulfoferrodoxin from De-
Natarajan Ravi, Jose J . G. Moura, Jean LeGaU, Yun-Hua sulfovibrio desulfuricans (ATCC 27774). Pedro Tavares,
Huang, B r i m R. Crouse, Michael K. Johnson, Boi Hanh Huynh, and Isabel Moura
Regulation of fluorescent fatty acid transfer from adi- pocyte and heart fatty acid binding proteins by acceptor membrane lipid composition and structure. Margo G. Wootan and Judith Storch
Multiple forms of the human tyrosine phosphatase RPTPa. Isozymes and differences in glycosylation.
ger, and Edmond H. Fischer Gunter Daum, Stephun Regenass, Jan Sap, Joseph Schlessin-
Misfolded human chorionic gonadotropin @subunits are secreted from transfected Chinese hamster ovary cells. Elliott Bedows, Sheila E. Norton, Jeffrey R. Huth, Nobuhiko Suganuma, Irving Boime, and Raymond W. Ruddon
Positively charged side chains in the insulin-like growth factor-1 C- and D-regions determine receptor binding specificity. Wengang Zhung, Thomas A. Gustafson, William J . Rutter, and Jeffrey D. Johnson
venom. Polypeptide composition and characterization Factor X-activating glycoprotein of Russell's viper
Jackson, Preston Hensley, and Eugene A. Davidson of the carbohydrate moieties. D. Channe Gowda, Craig M.
Indicates a Communication
xi
10764 The cytoplasmic domain of myelin glyco rotein Po in- teracts with negatively char ed phosphoEpid bilayers. Yungao Ding and Kurt R. B r u d e n
10849 Ranalexin. A novel antimicrobial peptide from bullfrog (Ram coteebeiana) skin, structurally related to the bacterial antibiotic, polymyxin. Dough P. Clurk, Stewart D u d , W . Lee Maloy, and Michael Zasloff
10856 Identification of a novel integrin binding site in fibro-
Bowditch, Meena Hariharan, Eiman F. Tominno, Jeffr W. nectin. Differential utilization by 83 integrins. Ron D.
Smith, Kenneth M. Yamuda, Elizabeth D. Getzoff, andgark H. Ginsberg
10883 The crystal structure o succinyl-CoA s nthetase from Escherichia coli at 2.5-f4 resolution. Wi&um T. Wolodko, Marie E. Fraser, Michael N. G. James, and WiUiam A. Brrdger
10946 Alternative licing governs sulfation of tyrosine or oligosacchar8e on peptidylglycine a-amidating monooxygenase. Hye-Young Yun, Henry T. Keutmann, and Betty A. Eipper
10964 Upfolding/refolding.studies on bovine @-lactoglobulin wlth monoclonal anthxhes as probes. Does a renatured protein completely refold? Vol. 2.68 (1993) 22414-
Makoto Shimizu, and Shuichi Kaminogawa 22419. Makoto Hattort, Aku, Ametanz, Yoshznorr Katakura,
10668 Structural coincidence of aPDGFR epitopes binding to platelet-derived growth factor-AA and a potent neu- tralizing monoclonal antibody. Jin-Chen Yu, Daruka Ma- hadevan, WiUiam J . LaRocheUe, Jacalyn H. Pierce, and Mo- hammod A. Heidaran
10675 Intermediate filament-like network formed in vitro by
Eeva-Liisa Nurmiaho-Lassila, and Mikael Rhen a bacterial coiled coil protein. Reini Hurme, Ellen Namork,
10683 Cloning and expression of a novel acidic calponin iso-
Applegate, Waldo Feng, Robert S. Green, and Mark B. form from rat aortic vascular smooth muscle. Dianne
Taubman
10691 In vitro characterization of nonpeptide irreversible in- hibitors of HIV proteases. Rafael Salto, Lilia M. Babi, Jia Li, Jason R. Rose, Zhonghua Yu, Alma Burlingame, James J. De Voss, Zhihua Sui, Paul Ortiz de Montellano, and Charles S. Craik
10734 She is the predominant signaling molecule coupling insulin receptors to activation of guanine nucleotide releasing factor and p21"GTP formation. Toshiyasu Sasaoka, Boris Draznin, J. Wayne Leitner, W. John Langlois, and Jerrold M. Olefsky
Aaronson, Stuart A,, 10753 Aggarwal, Bharat B., 10270 Aktories, Klaus, 10706 Allander, Susanne V., 10891 Ametani, Akio, 10964 Angel, Peter, 10363 Applegate, Dianne, 10683 Arai, Ken-ichi, 10905 Arrebola, Rosalia, 10590 Asano, Satoshi, 10205 Atkinson, John P., 10776 Atweh, George F., 10312 B a k , Lilia M., 10691 Badwey, John A,, 10813 Bagrodia, Shubha, 10247 Bajalica, Svetlana, 10891 Balboa, Maria A,, 10511 Banerjee, Asok, 10324 Banka, Carole L., 10288 Barber, Diane L., 10357 Barbieri, Joseph T., 10431 Baringhaus, Karl-Heinz,
Barter, Philip J., 10298 Bauer, Glenn, 10923
Bedows, Elliott, 10574 Beavis, Andrew D., 10614
Bell, Kelly S., 10511 Benett, Anton M., 10467 Benevides, James M., 10869 Benos, Dale J., 10235 Benovic, Jeffrey L., 10209 Berk, Bradford C., 10935 Bernstein, Kenneth E., 10935 Bevilacqua, Michael P.,
Black, Audrey S., 10288 Blaser, Martin J., 10566
Boger, Georg, 10621 Blumenfeld, Olga O., 10804
Boime, Irving, 10574 Bcquet, Patrice, 10706 Bowditch, Ron D., 10856 Brasier, Allan R., 10341 Bridger, William A., 10883 Brondyk, William H., 10229 Brunden, Kurt R., 10764 Buchner, Johannes, 10304 Burlingame, Alma, 10691 Bussolati, Ovidio, 10485 Cannell, David, 10370 Cao, Long, 10197
10621
10637
Cao, Ping, 10566 Caras, Ingrid W., 10830 Carter, Bing Z., 10699 Case, Randi D., 10467 Chassaing, Gerard, 10444 Chaturvedi, Madan M., 10270 Chedid, Marcio, 10753 Clark, Douglas P., 10849 Cline, Kenneth, 10189 Cohen, Stanley N., 10790,
Conley, Pam, 10651 Conti-Tronconi, Bianca M.,
Corin, Shari J., 10651 Cover, Timothy L., 10566 Cowan, Kenneth H., 10739 Cox, Graeme B., 10370 Cox, Gregory, 10820 Craik, Charles S., 10691 Crick, Dean C., 10559 Crouse, Brian R., 10504 Csaky, Karl G., 10753 Cuif, Marie-Helene, 10213 Curnutte, John T., 10813 Curtiss, Linda K., 10288 Dall'Asta, Valeria, 10485 Daum, Gunter, 10524 David, Michael, 10747 Davidson, Dominique, 10956 Davidson, Eugene A,, 10644 Davis, Richard C., 10319 de Castro Reinach, Fernando,
Deneris, Evan S., 10252
De Voss, James J., 10691 Derossi, Daniele, 10444
DHoore, An, 10324 Diaz-Guerra, Maria-Jose M..
Ding, Jiabing, 10813 Ding, Yungao, 10764 Doiron, Bruno, 10213 Dolce, Vincenza, 10451 Drapp, Darren A., 10193 Draznin, Boris, 10734 Drevet, Joel R., 10660 Duff, Jennifer L., 10935 Duncan, Roger F., 10913 Durell, Stewart, 10849 Eberbardt, Norman L., 10384 Ehrenborg, Ewa, 10891
10797
10407
10461
10213
AUTHOR INDEX
Eipper, Betty A,, 10946 Ek, Bo, 10438 El Khoury, Joseph, 10197 Endo, Noriaki, 10205 Engelborghs, Yves, 10324 Enhsen, Alfons, 10621 Eraso, Pilar, 10393 Erickson, Richard W., 10813 Eriksson, Inger, 10438 Ewart, Gary D., 10370 Falk, Eugen, 10621 Feldman, Gerald M., 10747 Feng, Waldo, 10683 Ferrari, Anna, 10312 Ferro, Jesus Aparecido, 10461 Field, Mark C., 10830 Fillingame, Robert H., 10221 Finbloom, David S., 10747 Fink, Jiirgen, 10621 Fiorella, Paul D., 10538 Firestein, Bonnie L., 10511 Fischer, Edmond H., 10524 Fischer, Petra, 10423 Flowers, Kevin M., 10201 Fournel, Marielle, 10956 Frank, Dara W., 10431 Frank, David W., 10559 Fraser, Marie E., 10883 Friedman, Scott L., 10551 Friedrich, Michael, 10621 Fritz, Gerhard, 10706 Furiya, Yoshiko, 10205 Furuya, Mayumi, 10729 Futai, Masamitsu, 10265 Fyodorov, Dmitry, 10252 Gack, Sabine, 10363 Garrahan, Patricio J., 10400 Garvey, Edward P., 10590 Gazzola, Gian C., 10485 Getzoff, Elizabeth D., 10856 Gilbert, Robin L., 10357 Ginsberg, Mark H., 10856 Girbig, Frank, 10621 Giry, Murielle, 10706 Glass, Jonathan, 10242 Glombik, Heiner, 10621 Goddard, Audrey, 10720 Godowski, Paul J., 10720 Godson, Catherine, 10511 Goers, John W., 10319 Goldsmith, Merrill E., 10739 Gonzalez-Pacanowska,
Gowda, D. Channe, 10644 Green, Robert S., 10683 Grossman, Lawrence, 10771 Gu, Qimin, 10720 Gurevich, Vsevolod V., 10209 Gustafson, Thomas A,, 10609 Gutjahr, Ulrike, 10621 Habib, Geetha M., 10699 Hagiwara, Hiromi, 10729 Hajnkzky, Gyorgy, 10280 Hanasaki, Kohji, 10637 Harbison, Lisa A., 10864 Hariharan, Meena, 10856 Hattori, Makoto, 10964 Hecht, Sidney M., 10899 Hegenbarth, Silke, 10706 Heidaran, Mohammad A.,
Henry, Ralph, 10189 Hensley, Preston, 10644 Herscher, Claudio J., 10400 Hess, Mark A,, 10913 Hickman, Suzanne E., 10197 Higuchi, Masahiro, 10270
Hoffmann, Axel, 10621 Hirose, Shigehisa, 10729
Holz, Ronald W., 10229 Hou, Cuifen, 10357 Howells, Anthony J., 10370 Huang, Cheng-Han, 10804 Huang, Yun-Hua, 10504 Hunt, Joan S., 10864
Huth, Jeffrey R., 10574 Hurme, Reini, 10675
Huynh, Boi Hanh, 10504 Iacobazzi, Vito, 10451 Iatrou, Kostas, 10660 Imakawa, Kazuhiko, 10864 Inglese, James, 10217 Inoue, Sadako, 10330 Inoue, Yasuo, 10330 Insel, Paul A,, 10511 Ismailov, Iskander I., 10235 Itakura, Makoto, 10729 Ito, Tomoko, 10498 Izuta, Shunji, 10225 Jackson, Craig M., 10644 James, Michael N. G., 10883 Jefferson, Leonard S., 10201 Jiang, Shi-Wen, 10384 Johnson, Jeffrey D., 10609
Dolores, 10590
10668
Johnson, Michael K., 10504 Joliot, Alain H., 10444 Juhasz, Ondrej, 10651 Just, Ingo, 10706 Kahn, Axel, 10213 Kahn, Richard A,, 10758 Kamata, Yoichi, 10498 Kaminogawa, Shuichi, 10964 Kane, Stefanie A., 10899 Kapazoglou, Aliki, 10189 Karlish, Steven J. D., 10780 Katakura, Yoshinori, 10964 Kato, Shigeaki, 10545 Kato, Yukio, 10545 Kedes, Larry, 10651 Keller, Gilbert-An&, 10830 Kent, Claudia, 10529 Keutmann, Henry T., 10946 Kiefer, Michael C., 10891 Kim, Ick Young, 10597 Kim, Ki-Han, 10475 Kim, Su Young, 10820 Kimball, Scot R., 10201 Kitajima, Ken, 10330 Kitazume, Shinobu, 10330
Koga, Yosuke, 10492 Kjellen, Lena, 10438
Konig, Stephan, 10879 Kosugi, Hiroshi, 10905 Kowalewski, Simone, 10621 Kozaki, Shunji, 10498 Krag, Sharon S., 10559 Kramer, Werner, 10621 Kretschmer, Axel, 10407 Kuizon, Luzette, 10229 Kulich, Scott M., 10431 Kumar, Amalendra, 10341 Kunapuli, Priya, 10209 Kwon, Young-Guen, 10966 Lagarias, J. Clark, 10965 Lammers, Reiner, 10423 Langlois, W. John, 10734 Larner, Andrew C., 10747 LaRochelle, William J.,
Larsson, Catharina, 10891 Lataro, Renata Cristina,
Laudano, Andrew P., 10247 Lawrence, David S., 10966 Lebovitz, Russell M., 10699 Lechleider, Robert J., 10467
10668
10461