Vitamin A palmitate | apollo +9191 46 950 950

Vitamin A palmitate | apollo +9191 46 950 950

Vitamin A palmitate

CAS Number : 79-81-2

Molecular Weight : 524.96 g/mol

Molecular Formula : C36H60O2

Systematic (IUPAC) : Retinolpalmitate (6CI,7CI);Retinol, palmitate, all-trans-

(8CI);250S/N;250S/N-B;Aquapalm;Aquasol A;Arovit;Arovit (Roche);Axerophthol

palmitate;DispatabsTabs;Lutavit A 500 Plus;Optovit A;Palmitic acid, ester withretinol.

Description of Vitamin A Palmitate Production

1. Vitamin A acetate is prepared synthetically by treatment of pseudoionone with sulfuric acid, and by condensation of the resulting β-ionone with methyl

chloroacetate to the “glycidic ester” intermediate, which is decarboxylated to β-C14-aldehyde.

2. Grignard reaction of β-C14-aldehyde with 3-methyl-2-penten-4-yn-1-ol gives the C20-alkynediol, which is

catalytically hydrogenated to C20-alkenediol.

3. Reaction of C20-alkenediol with acetic anhydride and subsequent dehydration with hydrobromic acid

gives then vitamin A acetate. The resulting crude product is purified by crystallization from methanol,

dried, and then filled into containers.

4. Vitamin A acetate reacts with methyl palmitate in the presence of sodium methoxide (or alternatively

sodium hydroxide) in a suitable solvent to give Vitamin A Palmitate, which is isolated by extraction. The

product is isolated by vacuum-concentration of the organic phase and then filled into containers.

VITAMIN A PALMITATE ORAL USES

Vitamin A is used to prevent or treat low levels of the vitamin in people who do not get enough of it from their

diets. Most people who eat a normal diet do not need extra vitamin A. However, some conditions (such as

protein deficiency, diabetes,hyperthyroidism, liver/pancreas problems) can cause low levels of vitamin

A. Vitamin A plays an important role in the body. It is needed for growth and bone development and to

maintain the health of the skin and eyesight. Low levels

of vitamin A may cause vision problems (such as night blindness) and permanent eye damage.

How to use vitamin A palmitate Oral

Take this vitamin by mouth with or without food, usually once daily. Follow all directions on the product package, or take as directed by your doctor. If you are uncertain

about any of the information, consult your doctor or pharmacist.

If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because

you may not get the correct dose.

Dosage is based on your age, medical condition, and response to treatment.

Use this vitamin regularly to get the most benefit from it. To help you remember, take it at the same time each

day. Do not increase your dose or use this vitamin more often than recommended. Your condition will not

improve any faster, and your risk of side effects will increase.

VITAMIN A PALMITATE ORAL SIDE EFFECTS

This vitamin usually has no side effects when used in recommended doses. If you have any unusual effects,

contact your doctor or pharmacist promptly.

A very serious allergic reaction to this vitamin is rare. However, seek immediate medical attention if you notice

any symptoms of a serious allergic reaction, including:rash, itching/swelling (especially of the

face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor

or pharmacist.

VITAMIN A PALMITATE ORAL PRECAUTIONS

Before taking vitamin A, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as

soy found in some brands),which can cause allergic reactions or other problems. Talk to your pharmacist for

more details.

During pregnancy, this vitamin has been found to be safe only when used in recommended doses. It must not

be used in doses that are higher than recommended because doing so may harm an unborn baby. Consult

your doctor for more details.

This vitamin passes into breast milk and is considered safe during breast-feeding when used in recommended

doses. Consult your doctor for more information.

VITAMIN A PALMITATE ORAL INTERACTIONS

The effects of some drugs can change if you take other drugs or herbal products at the same time. This can

increase your risk for serious side effects or may cause your medications not to work correctly. These drug

interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage

interactions by changing how you use your medications or by close monitoring.

To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all

the products you use (including prescription drugs, nonprescription drugs, and herbal products) before

starting treatment with this product. While using this product, do not start, stop, or change the dosage of any

other medicines you are using without your doctor's approval.

Some products that may interact with this vitamin include: acitretin, alitretinoin,bexarotene,

cholestyramine, isotretinoin, tretinoin, other products that contain vitamin A (such as multivitamins),

warfarin.

Avoid taking vitamin A at the same time as you take neomycin, orlistat, and mineral oil. If you take any of

these medications, separate your doses from your dose of vitamin A by at least 2 hours.

This document does not contain all possible drug interactions. Keep a list of all the products you use.

Share this list with your doctor and pharmacist to lessen your risk for serious medication problems.

NOTES

This product is not a substitute for a proper diet. It is best to get your vitamins from healthy foods. Vitamin A is commonly found in fruits (such as apricots, oranges, peaches), vegetables (such as carrots, sweet potatoes,

spinach), dairy products, and eggs, among others. Consult your doctor, pharmacist, or nutritionist for

more details.

MISSED DOSE

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose

and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE

Different brands of this vitamin have different storage needs. Check the product package for instructions on

how to store your brand, or ask your pharmacist. Do not store in the bathroom. Keep all medicines away from

children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard

this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal

company for more details about how to safely discard your product.

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