VISION REVIE W - Health Resource in Action · 2020-02-29 · Linley Nykiel-Bub, Grants Associate...

IN THIS ISSUE:About Us and Our Services /2

Our Team /3

Developing the Scientific Workforce /4

Taub Foundation /5

Maintaining Impact through Evaluation /6

Funding Opportunities

Hood Foundation /7

King Trust /8

Jeffress Trust /10

Lymphatic Education & Research Network /11

Noonan Memorial Research Fund /12

Patterson Trust /13

Geneen Trust /13

Smith Family Foundation /14

Thome Foundation /15

Scientific Review Committees /Back Cover

Where Science and Philanthropy Converge

DIVISIONRE V I E W

2014․

Board of DirectorsHealth Resources in Action

Harriet G. Tolpin, Ph.D., Chair

Lori Fresina, Co-Vice Chair

Joan Quinlan, M.P.A., Co-Vice Chair

Nelson A. Valverde, M.B.A., Treasurer

Ray Considine, M.S.W., President

Carole Allen, M.D.

Phil Caper, M.D.

Mary Fifield

Peter Hiam, Esq.

Maria Kieslich

Eric Kramer, Ph.D.

Thaleia Tsongas Schlesinger

Harry P. Selker, M.D., M.S.P.H.

Miles F. Shore, M.D.

From the President of Health Resources in Action Back in 1957, representatives from the Massachusetts Department of Public Health, the United Way, and The Boston Foundation saw the need for new ways of funding medical research and addressing emerging public health issues to promote better health on the community level. That vision led to the creation of The Medical Foundation, the predecessor of Health Resources in Action. Over the past 58 years the client dollars thatwe have invested and programs that we have managed have helped train thousands of physician researchers, spurred new discoveries in clinical careand changed the landscape for medical research. Our focus on preventing disease has led to declines in youth smoking rates and improvements inasthma care and enhanced the capacity of communities across the country to implement programs to improve health on the population level.

We are particularly proud of the impact that we have made in both supporting scientist careers and advancing population health. I am delighted to share our 2014 Medical Foundation Division Review with you. This year’s review highlights our clients’ work as well as introduces you to the newest member of our team, Robert Sege, M.D., Ph.D. Dr. Sege joins us as Vice President and director of our Medical Foundation division. He is a national leader in the field of pediatrics, both as a clinician and as a researcher, and throughout his career, he has worked to link clinical care and population health – a cornerstone of our work. Dr. Sege joins an extraordinary team of scientific and philanthropic professionals who make up our Medical Foundation division.

Our experience, our skilled staff, and the results that they have achieved are captured in this year’s Review. I hope you find it informative. We invite you to follow us at www.hria.org.

Ray Considine, President/CEO

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Services We Provide

Biomedical Research Grant Program Design

Extensive Contacts forFunding Announcements

Unbiased Peer Reviewby Distinguished Experts

Post-award Grant Oversight

Life Sciences Consulting

Grant Program Evaluation

Scientific Meetings and Symposia

Health Resources in Action’s Medical Foundation division assists philanthropic investment in health-related research. Working together with clients through our Life Sciences Consulting services, we strategically design high impact grant programs and conduct evaluations that inform and enhance existing programs. Our outstanding grantmaking maximizes the impact of funding dollars and our services include customized distribution of Program announcements, online grantsubmission, conducting unbiased, objective scientific reviews which draw on the expertise of distinguished senior scientists (see back cover), and professionally handling all administrative responsibilities from comprehensive award agreement negotiation to Award Recipients’ progress and financial reports.

In 2014, The Medical Foundation division administered grant programs for 11 philanthropic clients, awarding approximately $17.7 million dollars to 63 investigators in the basic sciences and 22 physician scientists at fifty research institutions. The funded research spanned biochemistry and nanotechnologies to preclinical animal disease models and clinical outcomes research. Award programs were designed to support investigators at specific career stages to best fit clients’ respective missions and maximize investment in the scientific workforce.

The Medical Foundation division also organizes other activities to further our clients’ missions. In order to drive scientific collaboration and to enhance the connection between Award Recipientsand foundation Trustees, informal luncheons and annual poster sessions are hosted. This year, a symposium was organized together with HRiA’s Community Health division to bring in speakers and to inform a Foundation’s Trustees of the ever-changing trends in both diabetes research and its prevention in the community.

This annual review describes each program in detail. The broad range of scientific focus and the excellence of the awardees attest to the vital role of private philanthropy in supporting innovative and transformational biomedical research whose breakthroughs will impact human health.

The Medical Foundation, a division of HRiAABOUT US

The Medical Foundation⁄ a

division of HRiA

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Gay Lockwood, M.S.W., Senior Program Officer Ms. Lockwood’s expertise is informed by 25 years of solid relationships with academic research institutions and senior scientists. She has launched several grants programs, oversees annual scientific meetings and continues to guide award recipients throughouttheir funding cycles. She brings organizational, resource and client relations skills from prior positions in both diplomatic and healthcare settings. ([email protected])

Jeanne Brown, Program Officer Ms. Brown’s experience is in project management, operations management and client relations in both healthcare and academic settings. She specializes in building processes for the delivery of efficient and comprehensive grantmaking services. She brings exceptional skills in planning, budget management and problem solving to the team. ([email protected])

Erin Johnstone, Program Officer Ms. Johnstone joined the division in 2013, bringing a variety of grants management experience in academic research and foundation settings. She manages several grant programs and is particularly interested in using technology to streamline their delivery. She holds a Graduate Certificate in Fundraising Management and brings additional skills in database administration and online application development. ([email protected])

Linley Nykiel-Bub, Grants Associate Ms. Nykiel-Bub is an integral part of the division’s workflow, providing operational support for grant programs and life science consulting projects. Her skill with computers and design is key in managing our extensive database and online application system, producing funding announcements and other media and updating division webpages. ([email protected])

In October 2014, Robert Sege, M.D., Ph.D., became Vice President. Dr. Sege has a background in basic cell biology and clinical research. Through two decades in leadership roles in academic medicine, he fully appreciates the challenges faced by investigators and the potential of private philanthropy to jump start careers as well as fund innovative, out-of the-box investigations across basic, translational and clinical research.He is an accomplished and widely cited investigator and national and international spokesperson on issues related to child health. Dr. Sege graduated from Yale College, received a Ph.D. in biology from MIT and an M.D. from Harvard Medical School. He completed internship and residency at Boston Children’s Hospital before joining Tufts Medical Center and then Boston Medical Center. ([email protected])

John Kanki, Ph.D., Scientific Director, works with Dr. Sege to provide scientific oversight and programmatic supervision for all programs in the division. Together with Dr. Sege, he conducts life sciences consulting projects that determine the best research funding strategies and performsgrant program assessments to maximize the impact of our clients’ investments in biomedical research. Dr. Kanki graduated from Wesleyan University and received his Ph.D. from the University of California San Diego. He did postdoctoral research at the University of Michigan,Princeton University, and the University of Pennsylvania. Prior to joining HRiA, Dr. Kanki was a Senior Research Scientist for 12 years at theDana-Farber Cancer Institute. He is an accomplished grant and scientific writer with an extensive publication record. ([email protected])

Our Team

The Medical Foundation, a division of HRiA

95 Berkeley Street, Suite 202

Boston, MA 02116

617.279.2251

www.tmfgrants.org/tmfservices

Developing the Scientific Workforce

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In their laboratory environment at Northeastern University. Dr. Kim Lewis (mentor) and

Dr. Brian P. Conlon (2014 King Award Recipient) work on newly discovered antibiotics.

Rebecca Scheck, Ph.D., Tufts University,

2014 Smith Award Recipient

Years of stagnant NIH funding have created substantial challenges, particularly for early-stage investigators. Strategicphilanthropic investment can address some of these problems.The Medical Foundation division oversees the annual distribu-tion of $15-$20 million in research awards, much of which focuson the particularly vulnerable early investigators, including post-doctoral fellows and junior faculty. Below are a few of the issuesfaced by young scientists, as they make the critical transitionfrom mentored trainee to independent investigator:

Is there a glut of postdoctoral fellows? Following completion of their Ph.D. work, the next step for most basic research scientists is another mentored training experience, the post-doctoral fellowship. During this time, postdoctoral fellows gainimportant experience while working in the laboratory of a seniorinvestigator. Meanwhile, the senior scientists gain the use of a highly trained – and relatively low-paid – scientific workforce. As funding and institutional budgets have tightened, most younginvestigators are facing extended time in postdoctoral positionsperforming the work of their mentors before they can find theirown research faculty positions. To offset this, private fundersthat support postdoctoral fellows, such as the Charles A. KingTrust, help bridge this period by allowing them to begin developing their own independent research programs.

Aging of the scientific workforce. NIH currently funds approximately 10% of research proposals. This high level ofcompetition has resulted in NIH review committees following apredictable trend toward safety, which favors more experienced,senior investigators. A 2012 NIH report showed that Ph.D. investigators receiving their first independent awards are now 42 years old and M.D. researchers are 44. Promising young research faculty are often required to sustain their early scien-tific careers through a combination of private philanthropic funding and institutional support. The success of programs that provide support during the first few years following facultyappointment include the Smith Family Awards Program for Excellence in Biomedical Research. These early stage invest-ments provide opportunities to acquire data and experience todevelop competitive federal grant applications. Our most recentevaluation of the Smith Program verified the critical role of philanthropic funding in the career development and future NIH support of these leading young scientists.

Lack of diversity in the scientific workforce. Although womennow comprise half of all medical and graduate biology students,they continue to be underrepresented in receipt of federal

funding. In addition, only about 2% of NIH-funded independent investigators are African-American. The Medical Foundation division staff is exploring how we can use our information andresources to help improve this situation. Next year, we hope toreport on new initiatives that will address the need for a more di-verse scientific workforce.

With the overarching goal of funding high impact biomedical research, The Medical Foundation division also recognizes thekey role of philanthropic investments and its role in shaping thegrowth and diversity of our future scientific workforce.

Program OfficerErin [email protected]

AwardThree-year awards of $600,000

Program EligibilityFaculty at nonprofit research institutions

Geographic EligibilityUnited States

Research FocusHigh-impact, innovativetranslational research tounderstand the underlyingcauses of MDS and to advance its treatment and prevention

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Introducing a New Program Launched in 2014:

Taub Foundation Grants Program for Myelodysplastic Syndromes ResearchA PROGRAM OF THE HENRY AND MARILYN TAUB FOUNDATION

Advancing translational research to find a cure for MDS

The Henry and Marilyn Taub Foundation is a family foundation located in BergenCounty, New Jersey. For over 45 years, the Taub Foundation has been making grantsto improve education, advance medical research, and strengthen local communitiesand Jewish life. The Medical Foundation division was engaged by the Taub Founda-tion to conduct a scan of the Myelodysplastic Syndromes (MDS) research landscape.Our interviews with senior scientific staff at foundations, the National Heart, Lung and Blood Institute and leading MDS researchers, guided Taub Foundation support towards new therapeutic development specific for MDS.

MDS is a disturbance of normal blood cell development that results in abnormalitiesin multiple blood cell types. These include red blood cells, platelets and a subset ofwhite blood cells. Although up to 30% of MDS patients go on to develop leukemia,nearly 70% of MDS patients die from the lack of one or more types of essential blood cells.

We found a gap in funding for MDS research. MDS receives far less funding thanleukemia, despite its higher mortality rate. Our life sciences consulting report sug-gested that philanthropic support specifically focused on MDS research could have a major impact. Following this recommendation, the Taub Foundation Grants Program for MDS Research was created. This program specifically focuses on MDS research, exclusive of leukemia. It supports innovative translational research to understand the underlying causes of MDS in order to advance its treatment and prevention. Projects focus on molecular genetics, epigenetics, splicing factors, stem cells, the microenvironment and novel therapeutic targets relevant to MDS.

Dr. John Kanki and Ms. Erin Johnstone successfully launched the Program in 2014. Over 60 innovative and highly competitive submissions were received from independent investigators at all stages of their careers, representing 36 research institutions across the nation. A Committee of seven renowned scientists invited 15 applicants to submit full proposals and awarded four grants, distributing a total of $2,400,000 over three years. An important mission of the Foundation is to expand the MDS research community through the Program’s continued support;this inaugural year marked a critical beginning.

2014 Award Recipients

Janis Abkowitz, M.D.University of Washington School of MedicineThe Pathogenesis of Anemia in MDS

Alan List, M.D.H. Lee Moffitt Cancer CenterTargeting MDS Stem Cell with a Novel TLR Selective Therapeutic Conjugate

Christopher Park, M.D., Ph.D.Memorial Sloan-Kettering Cancer CenterThe Contribution of Aging to the Pathogenesis of the Myelodysplastic Syndromes

Leonard Zon, M.D.Boston Children's HospitalRibosome Protein Deficiency and Modulation of p53 as a Therapeutic Target

Wright-Giemsa stain of a bone marrow aspirate for a patient with MDS. Courtesy of Drs. Janis Abkowitz (2014 Taub

Award Recipient) and Sindhu Cherian, University of Washington.

www.tmfgrants.org/Taub


division of HRiA

Dr. Janis Abkowitz directs the Division ofHematology at the University of Washingtonin Seattle. She received a 2014 Taub Awardfor her work which focuses on why patientswith myelodysplastic disorder do not makeenough red blood cells. Her project seeks tobetter understand the basic regulation of redblood cell production through bone marrowcells in patients with MDS.

The Medical Foundation division has long been a leader in the development of high-impact grant programs to fit the missionof our clients. Additional factors that determine a program’s impact include the understanding of a disease’s causes and treat-ment, its funding landscape, and the targeted scientific workforce.Each of these factors change over time. In order for programs tomaintain a high level of impact, it is recommended that they peri-odically step back to evaluate their success. Making program adjustments will continue to maximize their contribution towardstherapeutic development and potential cures.

Through our Life Sciences Consulting services, we recently assessed and evaluated the Programs of the Russell Berrie Foundation and the Richard and Susan Smith Family Foundation.

Since 2000, the Russell Berrie Foundation has supported postdoctoral fellows in diabetes research through The NaomiBerrie Fellowship Program at Columbia University. Our evaluationincluded a survey of past Award Recipients, interviews with deansand investigators, review of Award Recipient research and conven-ing a site visit by a panel of experts in diabetes research. The evaluation helped illuminate the awardee selection process, highlighted Program accomplishments and described its impact in launching productive scientific careers. Importantly, the evaluation informed program design, and recommended ways to monitor and improve program impact.

In 1991, the Smith Family Trustees began the Smith FamilyAwards Program for Excellence in Biomedical Research to support junior faculty conducting innovative basic research. The short-term goal of the Program is to provide newly independ-ent scientists the opportunity to demonstrate creativity and assistthem in the transition to other sources of research funding. The Program’s long-term mission is to fund promising young scientists who will contribute to the advancement of medical research discoveries throughout their careers. To maintain program excellence, the Smith Foundation’s Trustees engaged The Medical Foundation in 1996, 2007 and 2014 to monitorwhether the Program has been successfully meeting its purpose.Assessing career advancement, funding success and scientific literature published by Award Recipients, our findings substanti-ated the Program’s contribution to investigator innovation, inde-pendence and to scientific advances that impacted therapeuticdevelopment across a multitude of human diseases. Continuedprogram review coupled with instructive evaluation ensure theTrustees’ steadfast commitment to maximize the impact of theirProgram going forward.

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“The evaluations we have engaged The Medical Foundation to conductover the years have been very helpful to us in validating our program’soutcomes and guiding its evolution.” The Smith Family Foundation

Maintaining Impact through Evaluation

“We were certainly pleased with the evaluation which documentedthe considerable strengths and accomplishments of the program.We also greatly appreciated The Medical Foundation’s constructiveand collaborative approach to making recommendations that arebeing implemented and will deepen the impact of our FellowshipProgram.” The Russell Berrie Foundation

Laser Scanning Confocal Microscopy image of a section of two

different muscles from a Drosophila melanogaster larva stained for nuclei (magenta),

microtubules (green), and sarcomeres (blue). Courtesy of Torrey Mandigo and

Eric Folker, Ph.D., (2014 Hood Award Recipient), Boston College

Bayalpata Hospital in Achham, Nepal, the hub of excellence for Dr. Duncan Maru’s

implementation research. Courtesy of Matt Fleming and Duncan Maru, Ph.D. (2014 Hood

Award Recipient), Brigham and Women’s Hospital

Hood Foundation Child Health Research Awards ProgramA PROGRAM OF THE CHARLES H. HOOD FOUNDATION

Promoting child health through the support of early career investigators in New England

In the late 1880s, Charles Hood introduced pasteurization to his dairy company, significantly improving the health of thou-sands of New England children. In 1942, the Charles H. HoodFoundation was founded in his memory, with the mission to improve the health and quality of life for children in New England.The Foundation supports promising scientists at the beginning of their careers – offering them help in launching their researchcareers. In total, the Foundation has distributed over $63 million to New England investigators, many of whom are now leaders inchild health research. Under the present direction of Neil Smiley,the Hood Foundation will continue the family tradition of support-ing outstanding science to improve the lives of children.

A current 2014 Awardee, Dr. Eric Folker, Assistant Professor of Biology at Boston College, exemplifies the breadth of work supportedby the Hood Foundation. Using the fruit fly as a model system, Dr.Folker’s research focuses on the cellular and molecular basis of muscledevelopment and muscle disease in order to identify treatments forchildhood muscle illnesses. These include muscular dystrophy, centronuclear myopathy, and other disorders that cause progressive muscle weakness and loss of muscle mass.

Program OfficerGay [email protected]

AwardTwo-year awards in theamount of $150,000

Program EligibilityInvestigators within fiveyears of their first facultyappointment

Geographic EligibilityNew England

Research FocusClinical, basic science, public health, health services, and epidemiology research relevant to child health

www.tmfgrants.org/Hood


Andrea Ciaranello, M.D., M.P.H.Massachusetts General HospitalNovel Approaches to Improve Medication Adherence among HIV-infected Adolescents: the CEPAC-Adolescent Model

Eric Folker, Ph.D.Boston College The Role of Nuclear Positioning in Centronuclear Myopathies

Yick Fong, Ph.D.Brigham and Women's Hospital The Role of the Dyskerin Complex in Stem Cell-specific Transcriptional Control and the Pathogenesis of Dyskeratosis Congenita

Vandana Gupta, Ph.D. Boston Children's HospitalElucidation of Molecular Pathways and Therapeutic Developments in Nemaline Myopathy

Jun Jiang, Ph.D., M.D.University of Massachusetts Medical School Trisomy Correction in Down's Syndrome Mouse Models

Dong Kong, Ph.D.Tufts University School of MedicineMitochondria, Cognitive Defects, and Child Obesity

Rene Maehr, Ph.D. University of Massachusetts Medical SchoolDevelopment of a Pluripotent Stem Cell-based Approach to Model DiGeorge Syndrome

Duncan Maru, M.D., Ph.D.Brigham and Women's HospitalIntegrating Pediatric Care Delivery in Rural Healthcare Systems

Victor Navarro, Ph.D.Brigham and Women's Hospital The Role of Tachykinins in the Central Control of Sexual Maturation: Implications for the Timing of Puberty

Jessica Savage, M.D.Brigham and Women's Hospital Environmental Antimicrobial Chemicals and Allergic Disease

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The Medical Foundation ⁄ a division

of H

RiA

Charles A. King Trust Postdoctoral Fellowship Program

Understanding human disease and improving its treatment through postdoctoral research

The Charles A. King Trust, established in 1936, supports research that focuses on the causes of human disease in orderto discover cures or improve therapeutic treatment. To meet this goal, the Charles A. King Trust Postdoctoral Fellowship Program contributes to high impact discovery research by providing vital support that prepares fellows for launching productive academic careers as independent investigators in biomedical research.

Over the past 56 years, this program has supported over 800 postdoctoral fellows, many of whom have gone on to make extraordinary contributions in a wide-range of scientificdisciplines, including cancer, AIDS, heart disease, and diabetes.

In 2014, the Program received 170 applications which were read and critiqued by Scientific Review Committees comprisedof forty experts across many disease fields. Funding, in theamount of $1,827,000, provided two-year postdoctoral fellow-ships to 19 young investigators. The awards will support their career development, where their discoveries will contribute to accelerating medical innovations in research, training, and patient care. At the request of the Trustees, The Medical Foundation division will conduct an evaluation of the Program in 2015 in order to measure its past impact and plan for future contributions to medicine and patient care.

In addition to the outstanding commitment of the Charles A. King Trust, fellowship support has been generously provided by The Bushrod H. Campbell and Adah F. Hall Charity Fund, the Charles H. Hood Foundation, The Harold Whitworth Pierce Charitable Trust, the Sara Elizabeth O’Brien Trust, and theSimeon J. Fortin Charitable Foundation.

Postdoctoral fellows work closely with their faculty mentors to further develop their scientific careers. The resources andrecognition of the King Trust Fellowship support this close relationship and help launch independent scientific careers.

2014 Award Recipients Basic Science

Ozan Aygun, Ph.D.Massachusetts Institute of TechnologyUnveiling the Functional Complexity of Heterochromatin by Spatially-Resolved Live-Cell Proteomic Mapping

Luke Berchowitz, Ph.D.David H. Koch Institute for Integrative Cancer Research at MITTranslational Control in Germ Cell Development: Mechanisms and Signaling

Alison Burkart, Ph.D.Joslin Diabetes CenterDissecting Mechanisms by which Insulin Resistance Impairs Stem Cell Function and Metabolism in Human iPS Cells

Brian Conlon, Ph.D.Northeastern UniversityDetermining the Mechanism of Persister Formation and Resuscitation in Staphylococcus Aureus

Stavroula Hatzios, Ph.D.Brigham and Women's HospitalChemoproteomic Studies of Serine Hydrolases active during Vibrio Cholerae Infection

Katherine McJunkin, Ph.D.University of Massachusetts Medical SchoolMolecular Mechanisms of microRNA and Argonaute Turnover

Gulcin Pekkurnaz, Ph.D.Boston Children's HospitalO-GlcNAcylation: A Glucose Sensing Pathway for Mitochondria and Energy Homeostasis

Hyun Cheol Roh, Ph.D.Beth Israel Deaconess Medical CenterMolecular Mechanisms Underlying Beige Adipocyte Dynamics in Response to Thermal Challenges

Daniel Schmidt, Ph.D. Massachusetts Institute of TechnologyMolecular Tools for Precision Control of Cellular Signaling

Jianlong Sun, Ph.D.Boston Children's HospitalClonal Analysis of Hematopoiesis in Aging

Piuter Tsvetkov, Ph.D.Whitehead Institute for Biomedical ResearchHsp90 Regulation of Prion-Based Translation: Molecular Mechanisms and Evolutionary Conservation

Amyloid Burden and Alzheimer’s disease. Amyloid in the living brain visualized using PiB

PET imaging. Courtesy of Kathryn Papp, Ph.D. (2014 King Award Recipient), RA Sperling

M.D., KA Johnson M.D., Harvard Medical School, Harvard Aging Brain Study

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The Medical Foundation ⁄ a division

of H

RiA

BANK OF AMERICA, N.A., EDWARD DANE AND LUCY WEST, CO-TRUSTEES


division of HRiA

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Micrograph of a frog ovary depicting oocytes at various stages of growth and supporting

tissue and blood vessels. Courtesy of Martin Wühr, Ph.D., 2014 King Award Recipient,

Harvard Medical School

Thanks to new techniques, Dr. Martin Wühr can now identify and describe the subcellular distribution for thousands of proteins.In contradiction with current models, he is studying how hundredsof proteins injected into the cell find their way into the nucleus.These measurements will allow us to improve our understandingof the properties of the nuclear envelope and shed new light onfundamental principles of cellular organization in health and disease.

Dr. Kathryn Papp is a 2014 King Award Recipient in Clinical and Health Services Research. Her work is focused on Alzheimer’s disease, specifically the study of semantic memory (such as theability to remember the names of famous faces). Her goal is to determine if declines in language memory are a marker of impending Alzheimer's in otherwise healthy older adults. The most common cognitive complaint of older patients is word-finding difficulty and, therefore, Dr. Papp’s research may provide relevant outcome measures to be used in disease-modifying drugs and clinical guidelines for doctors working with older populations.

Songyu Wang, Ph.D.Harvard Medical SchoolMechanisms Involved in the Formation of the ER Network and Nuclear Envelope

Yinyuan Wu, Ph.D.Boston Children's HospitalPhosphorylation Recognition and Wnt Signaling Complex Assemblies by the Intrinsically Disordered Scaffold Protein Axin

Martin Wühr, Ph.D.Harvard Medical SchoolProteomics of Nucleocytoplasmic Partitioning

Dong Yan, Ph.D.Harvard Medical SchoolSplicing Regulation of Drosophila Germline Stem Cell Self-renewal and Signaling Transduction

Wen Yang, Ph.D.Harvard Medical SchoolMitochondrial Energy Status Regulate SIRT3 Interactome and Function

Xiaochang Zhang, Ph.D.Boston Children's HospitalMutations in QARS, Encoding Glutaminyl-tRNA Synthetase, Cause Progressive Microcephaly, Cerebral-Cerebellar Atrophy and Intractable Seizures

Clinical and Health Services Research

Noah Berman, Ph.D.Massachusetts General HospitalDifferential Effects of Positive and Negative Mood on OCD Treatment Response

Kathryn Papp, Ph.D.Brigham and Women's HospitalUsing Semantic Memory to Differentiate Normal Aging from Preclinical Alzheimer's Disease

Program OfficerErin [email protected]

AwardTwo-year fellowshipsranging from $87,000 - $102,000

Program EligibilityM.D. and Ph.D. researchers who are pursuing additionaltraining prior to their firstfaculty appointment.

Geographic EligibilityMassachusetts

Research FocusBasic science and clinical and health services research

www.tmfgrants.org/King

Below: In this image Opa proteins found in Neisseria gonorrheae and Neisseria

meningitides trigger the engulfment of the bacteria by human host cells. Courtesy

of Linda Colombus, Ph.D., 2014 Jeffress Award Recipient, University of Virginia

Jeffress Trust Awards Program in Interdisciplinary ResearchTHOMAS F. AND KATE MILLER JEFFRESS MEMORIAL TRUST

Expanding computational and quantitative research in Virginia

The Thomas F. and Kate Miller Jeffress Memorial Trust wasfounded in 1981 by Robert M. Jeffress in memory of his parentsand is guided by its mission, namely to benefit the people of Virginia in, and devoted to, research in chemical, medical orother scientific fields. Since its founding, the Jeffress MemorialTrust has been a steadfast benefactor in support of scientists and research of the highest quality across the state of Virginia.

The Jeffress Trust Awards Program in Interdisciplinary Researchfocuses on promoting the expansion of emerging computationaland quantitative strategies that accelerate discovery across allscientific fields. The Trust is dedicated towards inspiring youngcreative minds that will contribute to Virginia’s future scientific research workforce. Student participation and their mentorship is an important selection criteria for the Program.

In 2013, U.S. Trust retained The Medical Foundation division to manage the administrative aspects of the Jeffress Trust AwardsProgram. Since then the Program has supported 19 investigatorsacross a wide spectrum of disciplines with over $1.8 million distributed to Virginia’s colleges and universities.

Linda Columbus, Ph.D., received a 2014 Jeffress award for her studies of the structure of interaction between host cells andpathogens using cutting edge imaging and computer techniques. The Columbus and Kasson laboratory recently determined the structure of Opa60 and are currently investigating how Opa proteins interact with human receptors that mediate the uptake of the bacteria.

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Linda Columbus, Ph.D. University of VirginiaUsing Hybrid Computational and NMR Structure Determination to Study Host-pathogen Interactions at the Molecular Level

Denis Demchenko, Ph.D.Virginia Commonwealth UniversityMicroscopic Mechanisms of Defect Luminescence in Wide Bandgap Semiconductors

David Gauthier, Ph.D.Old Dominion UniversityAdvanced Phylogenomics of the Human and Animal Pathogen Mycobacterium marinum

Julia Halterman, Ph.D.Eastern Mennonite UniversityHigh-Salt Diet-Induced Regulation of NFAT5 in Hypertension

Christine May, Ph.D.James Madison UniversityDeveloping an Innovative Mathematical Simulation Model to Inform RecoveryStrategies for the Endangered James Spinymussel (Pleurobema collina)

Suzanne Robertson, Ph.D.Virginia Commonwealth UniversityThe Impact of Temporal Variation in Host Life-Stage Abundance on the Regional Transmission and Control of West Nile Virus

Michael Shirts, Ph.D.University of VirginiaUnderstanding and Predicting Pharmaceutical Binding to Blood Plasma Proteins

Ryan Taylor, Ph.D.Virginia Military InstituteInvestigation of Internal Thermally Active Oscillating Flows using Computa-tional Fluid Dynamics and Non-Contact Laser Imaging

Natalia Toporikova, Ph.D.Washington and Lee UniversityUsing Gene Expression and Mathematical Modeling to Uncover the Effects of Diet-induced Obesity on Reproductive Hormone Cycling and Fertility

Qi Wei, Ph.D.George Mason UniversityA Novel Computational Model to Study Human Eye Movement Disorders

Program OfficerJeanne [email protected]

AwardOne year awards of$100,000

Program EligibilityIndependent investiga-tors within seven yearsof their initial facultyappointment

Geographic EligibilityVirginia

Research FocusInterdisciplinary projects integratingcomputational andquantitative strategies

www.tmfgrants.org/Jeffress


division of HRiA

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Lymphatic Education & ResearchNetwork Postdoctoral FellowshipAwards ProgramWorking towards a world without lymphatic disease and lymphedema

Since 1998, the Lymphatic Education & Research Network (LE&RN), formerly the Lymphatic Research Foundation, has envisioned a world without lymphatic disease and lymphedema.LE&RN’s mission is to fight lymphatic disease and lymphedemathrough education, research and advocacy. In addition, theyseek to accelerate the prevention, treatment and cure of the disease while bringing patients and medical professionals together to address the unmet needs surrounding lymphatic disorders.

LE&RN is committed to expanding and strengthening the pool of outstanding young scientists in the field of lymphatic research.In 2014, two-year fellowships were awarded to investigators fromAustralia and Sweden. Their research will aid in broadening themedical community’s understanding of the lymphatic system and improving therapeutic development to address the millionswho suffer from lymphedema and lymphatic disease.

Dr. Katarzyna Koltowska (pictured above) received a 2014 LE&RN award for her work characterizing the molecular interac-tions responsible for regulating the development of lymphatic vessels.She uses zebrafish embryos to discover a new unstudied gene thatregulates the formation of the lymphatic system. Dr. Koltowska hopesthat her work will serve as an avenue to find new therapeutic targetsand approaches in lymphedema and vascular diseases.

Zebrafish facial lymphatic vessels visualized in red, blood vessels and eye in green.

Courtesy of Katarzyna Koltowska, Ph.D., 2014 LE&RN Award Recipient, IMB University of Queensland


Maike Frye, Ph.D.Uppsala University

Functional Characterization of Primary Lymphedema Gene GATA2

Katarzyna Koltowska, Ph.D.Institute for Molecular Bioscience, The University of Queensland

Characterization of a Novel Modulator of Vegfc/Vegfr3 Signaling during Lymphatic Development

Program OfficerErin Johnstone

[email protected]

AwardTwo-year fellowships

in the amount of$82,000 - $95,000

Program Eligibility Postdoctoral fellowswithin their first three

years of training

Geographic EligibilityWorldwide

Research FocusClinical and basic science research

relevant to the lymphaticsystem and LE&RN's

mission

www.tmfgrants.org/LERN

Program OfficerJeanne [email protected]

AwardOne-year awards in theamount of $80,000

Program EligibilityInvestigators working innonprofit organizations

Geographic EligibilityGreater Boston

Research FocusClinical research ordemonstrationprojects relevant tochildren withdisabilities

www.tmfgrants.org/Noonan

Deborah Munroe Noonan Memorial Research Fund Research to improve the lives of children with disabilities

The Deborah Munroe Noonan Memorial Research Fund, Bank of America, N.A., Trustee, was established in 1947 byFrank M. Noonan in memory of his mother to improve the lives of children who were left crippled by polio. The Fund now supports innovative clinical research or demonstration projects whose results may improve the quality of life for children with disabilities.

Six awards were funded in the 2014 grant cycle, one of which was sponsored by the Elizabeth O’Brien Trust, Bank of America, N.A., Trustee, in the area of childhood and adolescent blindness.

The Noonan Research Fund’s circle of influence is wide. Projects range from access to care, early intervention and other educational, health, and support programs to how newtechnology can assist in improving the lives of children and youth with special health care needs. Since its inception, 164 projects have been supported by the Noonan ResearchFund, greatly impacting the quality of life for the children of Greater Boston.


division of HRiA

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Alysa Doyle, Ph.D.Massachusetts General HospitalFeasibility and Effectiveness of Computerized Cognitive Training in Adolescents with Autism Spectrum Disorder

JoAnna Leyenaar, M.D., M.P.H.Tufts Medical Center"Nothing about me without me": Incorporating the Perspectives of Families ofChildren with Medical Complexity in Hospital-to-Home Transitional Care

Lotfi Merabet, Ph.D., M.P.H.Massachusetts Eye and Ear InfirmaryUncovering the Relationship between Brain Reorganization and Visual Dysfunction in Adolescents with Cortical Visual Impairment (CVI)

Esther Son, Ph.D., M.S.W.Brandeis UniversityUnderstanding the Health Care Experiences of Asian Children with SpecialHealth Care Needs on Health Care Access, Service Utilization, and Quality of Care

Angela Walter, Ph.D.Boston University School of Public HealthImpact of Case Management on Early Childhood Mental Health, Health Care Costs and Quality of Life

Marji Warfield, Ph.D.Brandeis UniversityMaking Healthy Connections: What are the Long-Term Benefits?

Dr. Angela Walter (pictured at left) is examining the impact of case management on costs and health outcomes for children andyouth with mental illness. Children and youth with mental healthconditions face challenges in accessing mental health services. Poor access may lead to diminished quality of care, health outcomes,and high health care costs. Dr. Walter’s team at the Boston UniversitySchool of Public Health will explore factors that influence patientand family engagement and retention in mental health care amongBlack/African American, Latino, and White families. This research has the potential to provide the field with an actionable set of health service utilization and policy recommendations.

PattersonProgram OfficerGay [email protected]

AwardOne-year awards in the amount of $75,000

Program EligibilityInvited faculty at nonprofit institutionsholding NIH K23 orK08 Awards

Geographic EligibilityConnecticut and New Jersey

Research FocusClinical researchacross a wide range ofresearch disciplines,including patient-oriented research and translational laboratory research

www.tmfgrants.org/Patterson

Patterson Trust AwardsProgram in Clinical

Research

The Robert E. Leet and Clara Guthrie Patterson Trust was created in 1980 to support research “relating to human diseases, their causes and relief.” The Patterson Trust Awards Program in ClinicalResearch provides support to early-stage physician scientists and clinical researchers in Connecticutand New Jersey. In 2014, the Program advanced clinical research by offering mentored K23 and K08Award Recipients additional resources to further explore, extend and promote their research activities.The funded clinical research included both patient-oriented research and translational laboratory research.

Sheela Shenoi, M.D., M.P.H., Assistant Professor at Yale School of Medicine, illustrates the tremendous talent of this year’s award winners. Despite improvements in access to HIV medications and improved HIVtesting, delayed HIV diagnosis and late presentation to care remain prevalent in impoverished areas in SouthAfrica, often leading to death. Dr. Shenoi will determine the barriers that HIV infected patients face initiating antiretroviral therapy and will pilot interventions to accelerate treatment onset for the millions still in need.

2014 Geneen Award Recipients

Annarita Di Lorenzo, Ph.D.Weill Medical College of Cornell University

Endothelial-derived Sphingolipids in Coronary Atherosclerosis

Timothy P. Fitzgibbons, M.D., Ph.D.University of Massachusetts Medical SchoolRationale and Discovery of A New Class of

Anti-Atherosclerotic Compounds; Ligands for the Orphan Nuclear Receptor Nurr77/NR4A1

Harold S. Geneen Charitable Trust Awards Program for Coronary Heart Disease Research

Supporting translational heart disease research

The Harold S. Geneen Charitable Trust Awards Program for Coronary Heart Disease Research supports research in the prevention and control of coronary and circulatory failure. In accordance

with Mr. Geneen’s directives, the 2014 Program established support for smaller academic or research institutions within the New England or New York areas by funding high-impact, innovative translational cardiology research. Working in conjunction with the Trustees, The Medical Foundation division identified two outstanding investigators for two-year

awards in the amount of $250,000 each.

ROBERT E. LEET AND CLARAGUTHRIE PATTERSON TRUST

Promoting human disease research by early-stage physician scientists

Research and education team in rural South Africa. Courtesy of Sheela Shenoi, M.D.,

M.P.H., 2014 Patterson Award Recipient, Yale School of Medicine

2014 Patterson Award Recipients

Michael Bloch, M.D.Yale School of MedicineA Randomized, Placebo-ControlledCrossover Trial of an N-methyl-D-as-partate Antagonist in the Treatmentof Social Anxiety Disorder

Bonnie Gould Rothberg, M.D., Ph.D.Yale School of MedicineGermline Genetic Variation in T2a-T4b Cutaneous Melanoma Prognosis

Jaimie Meyer, M.D.Yale School of MedicineDisentangling the Effect of Gender on HIV Treatment and Criminal Justice Outcomes: A 15-Year Retro-spective Cohort Study of HIV-InfectedPrisoners in Connecticut

Lauren Sansing, M.D.University of Connecticut Health CenterMonocyte Differentiation and Out-come after Intracerebral Hemorrhage

Carolyn Sartor, Ph.D.Yale School of MedicineThe Contributions of Genetic Liability, Parenting, and ChildhoodTrauma to the Development of Problem Substance Use in YoungAfrican-American and White Women

Sheela Shenoi, M.D., M.P.H.Yale School of MedicineAvoiding Delay in ART Initiation in Rural South Africa

Hanna Stevens, M.D., Ph.D.Yale School of MedicineDevelopmental Psychopathology andPrenatal Stress: Mechanisms and Prevention of Risk

Lauren Strober, Ph.D.Kessler FoundationUnemployment in Multiple Sclerosis(MS): Psychological and Health Outcomes

Emily Wang, M.D.Yale School of MedicineRisk of Morbidity and Mortality uponRelease from Correctional FacilitiesAmong Medicare Beneficiaries


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Smith Family Awards Program for Excellence in Biomedical ResearchA PROGRAM OF THE RICHARD AND SUSAN SMITH FAMILY FOUNDATION

Supporting biomedical innovation and discovery byearly-stage investigators

For the past 23 years, the Smith Family Foundation has been supporting groundbreaking medical research through the Smith Family Awards Program for Excellence in BiomedicalResearch. Its mission is to launch the careers of junior facultystudying health-related basic science with the ultimate goal ofachieving medical breakthroughs. Since its founding in 1992, the Program has funded 143 investigators for a total investment of $26.9 million.

The Smith Family Foundation hosted its annual poster session in May 2014 for its current and past Awardees. Thirty-two scientists showcased their projects and had the opportunity to meet with other scientists from many different fields.

Dr. Neil Ganem, Assistant Professor of Pharmacology and Medicine at B.U. School of Medicine and a 2014 Award Recipient, has focusedhis research on the basic biology of cancer cells. Unlike normalhuman cells that always have 23 pairs of chromosomes and stop dividing or die when they have abnormal chromosome numbers, cancer cells tolerate an abnormal number of chromosomes. An abnormal number of chromosomes in cancer cells is associated with tumor progression, resistance to chemotherapy, and cancer relapse. Dr. Ganem has discovered a new molecular pathway, calledthe Hippo pathway, which may prevent chromosomal instability innormal human cells. Understanding this pathway has the potential to uncover new therapeutic avenues to selectively kill chromosomallyunstable cancer cells.


Neil Ganem, Ph.D. Boston University School of MedicineMaintenance of Genome Stability by the Hippo Tumor Suppressor Pathway

Ya-Chieh Hsu, Ph.D. Harvard UniversityInvestigation of How Cell Types from Diverse Lineages Coordinate Changesand Behaviors during Regeneration

Karla Kaun, Ph.D. Brown UniversityNeuro-molecular Mechanisms Underlying Alcoholism

Michael Lee, Ph.D. University of Massachusetts Medical SchoolMicro-Environmental Regulation of Network State and Drug Sensitivity in Triple-Negative Breast Cancer

Rebecca Scheck, Ph.D. Tufts UniversityMapping the Uncharted: Encodable Chemistry to Discover the Role of Glycation in Disease

Mario Suva, M.D., Ph.D. Massachusetts General HospitalUncovering the Role of Epigenetic Programs in Glioblastoma

A human cell (shown in multiple colors) undergoing an abnormal multipolar cell division.

Courtesy of Neil Ganem, Ph.D., 2014 Smith Award Recipient,

Boston University School of Medicine

Program OfficerGay [email protected]

AwardThree-year awards in the amount of$300,000

Program EligibilityInvestigators within twoand a half years of theirfirst independent facultyappointment

Geographic EligibilityMassachusetts, YaleUniversity and BrownUniversity

Research FocusBasic biomedical science

www.tmfgrants.org/Smith


division of HRiA

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Edward N. and Della L. Thome Memorial Foundation Awards Program in Age-Related Macular Degeneration Research Fighting the leading cause of blindness in older adults

Established in 2002, the Edward N. and Della L. Thome Memorial Foundation, Bank of America, N.A., Trustee, advancesthe health of older adults through the support of direct serviceprojects and medical research on diseases and disorders affect-ing older Americans. The Trust’s Awards Program in age-relatedmacular degeneration research addresses the major cause ofblindness in older adults.

In 2014, awards in the amount of $500,000 each were made to six scientists from a pool of 111 preliminary applications fromacross the United States. After review, twenty-two investigatorswere invited to submit full proposals. Using this mechanism, the Thome Foundation was able to select truly extraordinary scientific proposals in the field of age-related macular degeneration.

Typical of these awardees is Dr. Joseph Carroll, Professor of Ophthalmology at the Medical College of Wisconsin. Dr. Carroll and his colleagues will generate high resolution images of the retinasof patients and volunteers in order to identify patients at the greatest risk for progressive vision loss and to monitor their response to treatment.

Top of page: Adaptive optics image of the cone photoreceptor mosaic overlying

drusen in a man with AMD. With this imaging technique it is possible to resolve cones

even when they are damaged. Courtesy of Joseph Carroll, Ph.D., 2014 Thome AMD Award

Recipient, Medical College of Wisconsin


Radha Ayyagari, Ph.D.University of California, San Diego

Insights into AMD Derived from the Genetic Mechanisms in Late Onset Retinal Macular Degeneration (L-ORMD)

Joseph Carroll, Ph.D.Medical College of Wisconsin

Improving Therapeutic Strategies in Age-Related Macular Degeneration Using Adaptive Optics Retinal Imaging

Richard Kramer, Ph.D.University of California, Berkeley

Mechanism of Re-animation of the Blind Retina by Synthetic Photoswitch Compounds

Goldis Malek, Ph.D.Duke University

Targeting the Signaling Pathway of a Lipid Activated Nuclear Receptor for the Treatment of Early Dry Age-related Macular Degeneration (AMD)

Richard Semba, M.D., M.P.H. Johns Hopkins University

Identifying the Roles of ARMS2 and HTRA1 in the Pathogenesis of Age-Related Macular Degeneration Using Functional Proteomics

Donald Zack, M.D., Ph.D.Johns Hopkins University School of Medicine

Development of a Small Molecule Only Protocol for the Directed Differentiation of RPE from hPSC for the Treatment of AMD

Program OfficerErin Johnstone

[email protected]

AwardTwo-year awards in theamount of $500,000

Program EligibilityFaculty at nonprofit research institutions(next grant cycle in

2016)

Geographic EligibilityUnited States

Research FocusTranslational

research that will leadto improved therapiesfor individuals suffering

from AMD

www.tmfgrants.org/ThomeAMD

Charles A. King Trust Postdoctoral Fellowship Program(Basic Science Research)

Jeannie Lee, M.D., Ph.D. (Chair)Ingolf Bach, Ph.D.Steve Buratowski, Ph.D.David M. Center, M.D.James Chou, Ph.D.Bennett Goldberg, Ph.D.Dale Greiner, Ph.D.Lizbeth Hedstrom, Ph.D.Takao Hensch, Ph.D.Ann Hochschild, Ph.D.Paul Huang, M.D., Ph.D.Robin Ingalls, M.D.Jonathan Kagan, Ph.D.Donald Katz, Ph.D.Michelle Kelliher, Ph.D.Gabriel Kreiman, Ph.D.Carl Novina, M.D., Ph.D.Norbert Perrimon, Ph.D.William Pu, M.D.Samara Reck-Peterson, Ph.D.Daniel Remick, M.D.Michael Rosbash, Ph.D.Ralph Scully, Ph.D.Ramesh Shivdasani, M.D., Ph.D.Hazel Sive, Ph.D.Lois Smith, M.D., Ph.D.Kevin Struhl, Ph.D.William Theurkauf, Ph.D.Vickery Trinkaus-Randall, Ph.D.Johannes Walter, Ph.D.David Waxman, Ph.D.Matthew Wilson, Ph.D.

Charles A. King Trust Postdoctoral Fellowship Program(Clinical and Health Services Research)

Bruce Landon, M.D., M.B.A. (Chair)Shelly Greenfield, M.D., M.P.H.Nan Laird, Ph.D.Kenneth Mukamal, M.D., M.P.H.Deborah Schrag, M.D., M.P.H.Christine Wanke, M.D.Carl-Frederik Westin, Ph.D.

Deborah Munroe Noonan Memorial Research FundLaurel Leslie, M.D., M.P.H. (Chair)Susan Bruce, Ph.D.Eugenia Chan, M.D., M.P.H.Karen Kuhlthau, Ph.D.Gael Orsmond, Ph.D.Susan L. Parish, Ph.D.Richard Robison, D.Min.Robert Volpe, Ph.D.

Edward N. & Della L. Thome Memorial Foundation Program in Age-Related Macular Degeneration ResearchJoan Miller, M.D. (Chair)Kapil Bharti, Ph.D.Catherine Bowes Rickman, Ph.D.Constance Cepko, Ph.D.Emily Chew, M.D.Margaret DeAngelis, Ph.D.James Handa, M.D.Sabri Markabi, M.D.Erich Strauss, M.D.

Hood Foundation Child Health Research AwardsProgramJordan Kreidberg, M.D., Ph.D. (Chair)Clifford Bogue, M.D.Bobby Cherayil, M.D.Jonathan Davis, M.D. Elizabeth Engle, M.D.Catherine Gordon, M.D., M.Sc.Beth McCormick, Ph.D.Stephen Pelton, M.D.David Rowe, M.D.James Sargent, M.D.Surendra Sharma, Ph.D.Susanne Tanski, M.D., M.P.H.Paige Williams, Ph.D.

Lymphatic Education & Research Network PostdoctoralFellowship Awards ProgramMihaela Skobe, Ph.D. (Chair)Mark Kahn, M.D.Jan Kitajewski, Ph.D.Taija Mäkinen, Ph.D.Nancy Ruddle, Ph.D.

Patterson Trust Awards Program in Clinical ResearchLori Bastian, M.D., M.P.H.Clifford Bogue, M.D.Cary Gross, M.D.Gordon Huggins, M.D.George Kuchel, M.D.Mark Litt, Ph.D.Heber Nielsen, M.D.Cheryl Oncken, M.D.Susan Reisine, Ph.D.David Steffens, M.D.

Smith Family Awards Programfor Excellence in BiomedicalResearchTyler Jacks, Ph.D. (Chair)Catherine Dulac, Ph.D.Iain Cheeseman, Ph.D.Nathanael Gray, Ph.D.Leslie Griffith, M.D., Ph.D.Louis Kunkel, Ph.D.Venkatesh Murthy, Ph.D.Aviv Regev, Ph.D.Ann Rothstein, Ph.D.Gary Ruvkun, Ph.D. David Scadden, M.D.Matthew Waldor, M.D., Ph.D.Muhammad Zaman, Ph.D.

Taub Foundation Grants Programfor MDS ResearchGuillermo Garcia-Manero, M.D. (Chair)Peter Aplan, M.D.Benjamin Ebert, M.D., Ph.D.Aly Karsan, M.D.Ross Levine, M.D.Jaroslaw Maciejewski, M.D., Ph.D.Stephen Nimer, M.D.

Jeffress Trust Awards Program in Interdisciplinary Research

Donald Brown, Ph.D. (Chair)David Chan, Ph.D.Andrey Chernikov, Ph.D.John Delos, Ph.D.James Gentle, Ph.D.Ina Hoeschele, Ph.D.Debra Hydorn, Ph.D.Glen Kellogg, Ph.D.Yiannis Papelis, Ph.D.Thomas Russell, Ph.D.Jeff Saucerman, Ph.D.Leah Shaw, Ph.D.Diego Troya, Ph.D.

On the Cover: The Oocyte-to-Embryo

Transition – Fertilization initiates the remarkable

conversion of quiescent, developing oocytes into

actively dividing embryos. A micrograph of a two

cell stage frog embryo overlays a micrograph of

a frog ovary containing oocytes at different

developmental stages. Images courtesy of Martin

Wühr, Ph.D., 2014 King Award Recipient,

Harvard Medical School

2014 Scientific Review CommitteesEach year, Scientific Review Committee members contribute their expertise as well as hundreds of hours to read, discuss and ultimately recommend to clients the most outstanding applicants for funding. We are grateful for their service and thank them for their commitment.

VISION REVIE W - Health Resource in Action · 2020-02-29 · Linley Nykiel-Bub, Grants Associate...

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Transcript of VISION REVIE W - Health Resource in Action · 2020-02-29 · Linley Nykiel-Bub, Grants Associate...