VASODILATORS
-
Upload
michikoloistao203 -
Category
Documents
-
view
148 -
download
0
Transcript of VASODILATORS
![Page 1: VASODILATORS](https://reader036.fdocuments.net/reader036/viewer/2022082918/551edf9d49795987458b486f/html5/thumbnails/1.jpg)
VASODILATORSMNEMONICS:
Classifications: COP SI RAAS
CALCIUM CHANNEL BLOCKERSORGANIC NITRATESDRUGS FOR PULPMONARY ARTERIAL HYPOTENSION
SYMPATHOLYTIC DRUGSINDIVIDUAL VASODILATOR
DRUGS ACTING ON THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM
CLASSIFICATIONCATEGORY
MECHANISM OF ACTION DRUGS (Generic-Trade name) Drug MNEMO
NICS
1.) INDIVIDUAL VASODILATOR
Some of the drugs act primarily on arterioles, some act on veins, and some act in both the type of vessel. Some agents produce selective dilation of arterioles.
MinoxidilSodium NitroprussideDiazoxideHydralazine
MiSoDiHy
2.) DRUGS ACTING ON THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM
Plays an important role in regulation of BP, blood volume, and fluid and electrolyte balance, a key component of the system – angiotensin II is a powerful vasoconstrictor that acts on arterioles and veins. Hence, by blocking either the formation or actions of angiotensin II, we can promote dilation of arterioles and veins.
CaptoprilLosartanAliskirenValsartanEnalapril
CLAVE
3.) ORGANIC NITRATES
Produce selective dilation of veins; dilation of arterioles is minimal. The primary indication for these drugs is angina pectoris; In addition, nitroglycerin is given to treat heart failure and myocardial infarction, and to provide controlled hypotension during surgery.
NitroglycerinIsosorbide dinitrate
Niso
4.) CALCIUM CHANNEL BLOCKERS
Produce vasodilation by preventing calcium entry into VSM. At therapeutic doses, these drugs produce selective dilation of arterioles. Primary indications are hypertension and angina pectoris.
DiltiazemVerapamilNifedipineIsrapidine
DiVeNi
5.) SYMPATHOLYTIC DRUGS
Promotes vasodilation by preventing the sympathetic nervous system from causing
PrazosinTerazosin
PleaseTell
![Page 2: VASODILATORS](https://reader036.fdocuments.net/reader036/viewer/2022082918/551edf9d49795987458b486f/html5/thumbnails/2.jpg)
vasoconstriction. Some of these drugs act by direct blockade of vascular adrenergic receptors. Others on sympathetic ganglia, adrenergic neurons, or the CNS.
MecamylamineGuanadrelClonidineReserpine
PhentolaminePhenoxybenzamineMethyldopa
MyGrandChildRyan
6.) DRUGS FOR PULPMONARY ARTERIAL HYPOTENSION
Used to dilate pulmonary blood vessels in patients with pulmonary arterial hypertension. Ambrisentan bosentan block vascular receptors for endothelin-1, a powerful vasoconstrictor. Epoprostenol and treprostinil stimulate production of cyclic AMP in vascular smooth muscle.
BosentanEpoprostenolBosentanTrepostinil
BEBoT