V21N43 PCT 2ND - Intellectual Property Office · Intellectual Property Center, 28 Upper McKinley...

Intellectual Property Center, 28 Upper McKinley Rd. McKinley Hill Town Center, Fort Bonifacio, Taguig City 1634 Philippines

Tel. No. 238-6300 Website: http://www.ipophil.gov.ph e-mail: [email protected]

Volume 21 Number 43 Date Released: April 20, 2018

Invention Granted Under R.A. 8293 (PCT)

1 INVENTIONS

[19] INTELLECTUAL PROPERTY PHILIPPINES

[12] INVENTION GRANT

[21] Registration Number: 1/2010/501385 Document Code: B1

[45] Issue Date: 9 February 2018

[22] Date Filed: 17 June 2010

[54] Title: DOSING REGIMEN ASSOCIATED WITH LONG ACTING INJECTABLE PALIPERIDONE ESTERS

[71] Proprietors(s): JANSSEN PHARMACEUTICA N. V., [BE]

[72] Inventor(s): WOUTERS, Alfons Jeanne[BE]: VERMEULEN, An Margriet Cornelia[BE]

[73] Assignee(s): JANSSEN PHARMACEUTICA N. V., [BE]

[74] Attorney / Agent: ROMULO MABANTA BUENAVENTURA SAYOC AND DELOS ANGELES

[30] Priority Data: 61/014,918 19/12/2007 US and 61/120,276 05/12/2008 US

[51] International Class 8: A61K 31/41; A61K 31/42; A61K 31/445; A61K 31/519; A61P 25/18; C07D 471/04

[57] Abstract: The present invention provides a method of treating patients in need of treatment with long acting injectable paliperidone palmitate formulations.

Representative Drawing(s):




[56] Reference(s) Cited and/or Considered:

Document description CLETON A ET AL: "Effects of renal impairment on the pharmacokinetic profile..."CLIN. PHARMA. & THERA., MOSBY-YEAR BOOK, ST LOUIS, MO, US, vol. 81, no. Suppl. 1, 1 March 2007, page S63, XP009114090 ISSN: 0009-9236. REVILL P ET AL: "Paliperidone-Antipsychotic agent, treatment of bipolar disorder, dual dopamine ..."DRUGS OF THE FUTURE, PROUS SCIENCE, ES, vol. 31, no. 7, 1 July 2006, pages 579-584, XP008096915 ISSN: 0377-8282. US 2007/197591 A1 (BOOM SANDRA, ET AL.) 23 August 2007.

No. of Claims: 57








[22] Date Filed: 23 March 2011

[54] Title: TISSUE OCCLUDING AGENT

[71] Proprietors(s): 3~D MATRIX, LTD. [JP]

[72] Inventor(s): TAKAMURA, Kentaro[JP]: KOBAYASHI, Satoru[JP]: GOJO, Satoshi[JP]

[73] Assignee(s): 3~D MATRIX, LTD. [JP]

[74] Attorney / Agent: E.B. ASTUDILLO AND ASSOCIATES

[30] Priority Data: 2008-259860 06/10/2008 JP and 2008-316133 11/12/2008 JP

[51] International Class 8: A61K 38/00; A61L 17/00; A61L 31/00; A61L 31/04; A61L 31/14; A61P 7/04

[57] Abstract:

There is provided a bioabsorbable peptide tissue occluding agent that can be applied to large mammals including humans, the peptide tissue occluding agent being obtained by artificial synthesis to avoid concerns of infection by viruses and the like. The tissue occluding agent contains a peptide, wherein the peptide is an amphiphilic peptide having 8-200 amino acid residues with the hydrophilic amino acids and hydrophobic amino acids alternately bonded, and is a self-assembling peptide exhibiting a ß-structure in aqueous solution in the presence of physiological pH and/or a cation.



Document description US 2008/032934 A1 (ELLIS-BEHNKE RUTLEDGE, ET AL.) 7 February 2008. ZHAOYANG YE ET AL.: "Temperature and pH effects on




biophysical and morphological properties of self-assembling...." JOURNAL OF PEPTIDE SCIENCE vol. 14, no. 2, 14 January 2008, pages 152-162, XP008146649. WO 2008/039483 A2 (MASSACHUSETTS INST TECHNOLOGY, ET AL.) 3 April 2008.

No. of Claims: 36








[22] Date Filed: 27 May 2011

[54] Title: BOVINE VIRAL DIARRHEA VIRUS WITH A MODIFIED ERNS PROTEIN

[71] Proprietors(s): ZOETIS SERVICES LLC [US]

[72] Inventor(s): No Natural Type Inventor[US]: ANKENBAUER, ROBERT GERARD[US]: LUO, YUGANG[US]: WELCH, SIAO-KUN WAN[US]

[73] Assignee(s): ZOETIS SERVICES LLC [US]



[51] International Class 8: A61K 39/12; C07K 14/18; C07K 16/10; C12N 15/86; C12N 7/04; G01N 33/50

[57] Abstract:

The present invention relates to chimeric pestiviruses having utility as immunogenic compositions and vaccines wherein said chimeric pestivirus comprises a bovine viral diarrhea virus which does not express its homologous Ems protein, further wherein said chimeric pestiviruses expresses a heterologous Ems protein derived from another pestivirus, or a natural, synthetic or genetic variant of said heterologous Ems protein. Also described herein are methods and kits for treating or preventing the spread of bovine viral diarrhea virus inspection, as well as methods and kits for differentiating between vaccinated and wild-type infected animals.

Representative Drawing(s): NONE

[56] Reference(s) Cited and/or Considered: NONE

No. of Claims: 22








[22] Date Filed: 21 January 2013

[54] Title: AGONISTS OF GPR40

[71] Proprietors(s): CONNEXIOS LIFE SCIENCES PVT. LTD. [IN]

[72] Inventor(s):

RANGANATH RAO, Jagannath Madanahalli[IN]: ARUMUGAM, Nagarajan[IN]: ANSARI, Mohd Mudabbir[IN]: GUDLA, Chandrasekhar[IN]: PACHIYAPPAN, Shanmugam[IN]: RAMALINGAM, Manivannan[IN]: GEORGE, Jenson[IN]: ARUL, George Fernanda[IN]: BOMMEGOWDA, Y Kenchegowda[IN]: ANGUPILLAI, Sathesh Kumar[IN]: KOTTAMALAI, Ramamoorthy[IN]: JIDUGU, Pradeep[IN]: RAO, D Shivanageshwara[IN]

[73] Assignee(s): CONNEXIOS LIFE SCIENCES PVT. LTD. [IN]

[74] Attorney / Agent: HECHANOVA & CO., INC.

[30] Priority Data: 2110/CHE/2010 23/07/2010 IN and 61/389,508 04/10/2010 US

[51] International Class 8: A61K 31/343; A61K 31/381; A61K 31/42; A61P 9/00; C07C 251/48; C07C 251/52; C07C 255/41; C07C 255/61; C07C 317/32; C07D 261/08; C07D 307/79; C07D 333/58; C07F 9/40

[57] Abstract:

The present invention relates to compounds that have the ability to modulate the activity of GPR40 and are therefore useful in the treatment of GPR40 related disorders. In addition the invention relates to the compounds, methods for their preparation, pharmaceutical compositions containing the compounds and the uses of these compounds in the treatment of certain disorders related to GPR40 activity.



Document description US 5 484 786 A (DELLARIA JOSEPH F [US] ET AL) 16 January 1996 (16.01.1996) US 5 516 795 A (DELLARIA JOSEPH F [US] ET AL) 14 May 1996 (14.05.1996) EP 0 280 240 A2 (BANYU PHARMA CO LYD [JP]) 31 August 1988 (31.08.1988) EP 1 176 139 A1 (SHIONOGI & CO [JP]) 30 January 2002 (30.01.2002) WO 2009/038204 A1 (PHARMA FRONTIER CO LTD {JP]; TSUJIMOTO GOZOH [JP]; HIRAS) 26 March 2009 (26.03.2009)

No. of Claims: 91








[22] Date Filed: 19 April 2013

[54] Title: TRANSDERMAL THERAPEUTIC SYSTEM

[71] Proprietors(s): NOVARTIS AG [CH] and LTS LOHMANN THERAPIE-SYSTEME AG [DE]

[72] Inventor(s): GARGIULO, Paul, M.[US]: LANE, Roger, Michael[GB]: PLATT, Beatrix[DE]: THEOBALD, Frank[DE]: WALL, Bettina[DE]

[73] Assignee(s): NOVARTIS AG [CH] and LTS LOHMANN THERAPIE-SYSTEME AG [DE]

[74] Attorney / Agent: E. B. ASTUDILLO & ASSOCIATES

[30] Priority Data: 60/741,511 01/12/2005 US

[51] International Class 8: A61K 31/27; A61K 9/70

[57] Abstract: The present invention relates to Transdermal Therapeutic Systems having a silicone adhesive layer, to Transdermal Therapeutic Systems providing specific plasma concentrations, to their manufacture and use.



Document description WO 01/32115 A (XEL HERBACEUTICALS [US]) 10 May 2001 WO 03/047556 A (LOHMANN THERAPIE SYST LTS [DE], et al.) 12 June 2003

No. of Claims: 1









[54] Title: CXCR2 BINDING POLYPEPTIDES

[71] Proprietors(s): NOVARTIS AG [CH]

[72] Inventor(s): BRADLEY, Michelle[GB]: BROWN, Zarin[GB]: CHARLTON, Steven John[GB]: CROMIE, Karen[GB]: DOMBRECHT, Bruno[BE]: STEFFENSEN, Soren[DK]: VAN HEEKE, Gino[BE]

[73] Assignee(s): NOVARTIS AG [CH]


[30] Priority Data: 61/411,083 08/11/2010 US

[51] International Class 8: C07K 16/28

[57] Abstract:

The present invention relates to polypeptides directed against or specifically binding to chemokine receptor CXCR2 and in particular to polypeptides capable of modulating signal transduction from CXCR2. The invention also relates to nucleic acids, vectors and host cells capable of expressing the polypeptides of the invention, pharmaceutical compositions comprising the polypeptides and uses of said polypeptides and compositions for treatment of diseases involving aberrant functioning of CXCR2.



NONE

No. of Claims: 36









[54] Title: ORALLY DISINTEGRATING TABLET

[71] Proprietors(s): TAKEDA PHARMACEUTICAL COMPANY LIMITED [JP]

[72] Inventor(s): MIMA, Yasushi[JP]: KAWANO, Tetsuya[JP]: MIZUNO, Yumiko[JP]

[73] Assignee(s): TAKEDA PHARMACEUTICAL COMPANY LIMITED [JP]

[74] Attorney / Agent: ORTEGA BACORRO ODULIO CALMA AND CARBONELL

[30] Priority Data: 2010-270276 03/12/2010 JP

[51] International Class 8: A61K 31/4439; A61K 31/616; A61K 47/04; A61K 47/32; A61K 47/36; A61K 47/44; A61K 9/24; A61K 9/26; A61P 1/04; A61P 29/00; A61P 43/00; A61P 9/10

[57] Abstract:

The present invention relates to a multi-layer orally disintegrating tablet having (1) an enteric fine granule-containing layer containing a proton pump inhibitor and (2) an acetylsalicylic acid-containing layer, which shows high stability of the active ingredients (proton pump inhibitor, acetylsalicylic acid) and expresses the pharmacological effects of the active ingredients stably and rapidly after administration.



Document description JP 11-501498 A (ASTRA AB.) 16 February 1999 JP 2009-517466 A (ASTRA ZENECA AB.) 30 April 2009

No. of Claims: 19









[54] Title: DEVELOPING ROLLER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS

[71] Proprietors(s): CANON KABUSHIKI KAISHA [JP]

[72] Inventor(s): YAMADA, Masaki[JP]: KUSABA, Takashi[JP]: KAWAMURA, Kunimasa[JP]: SAKURAI, Yuji[JP]: ISHII, Toru[JP]

[73] Assignee(s): CANON KABUSHIKI KAISHA [JP]

[74] Attorney / Agent: SALUDO FERNANDEZ AQUINO & TALEON

[30] Priority Data: 2010-292765 28/12/2010 JP

[51] International Class 8: G03G 15/08

[57] Abstract:

Provided is a developing roller, which is suppressed in separation of a surface layer from an elastic layer in cases where the developing roller is stored and used in high-temperature high-humidity environments, and wherein a toner does not easily adhere to the surface. The developing roller is capable of forming high-quality electrophotographic images. The developing roller comprises: an axial core body; an elastic layer that is provided on the axial core body and contains a cured product of an addition-curable dimethyl silicone rubber; and a surface layer that covers the circumferential surface of the elastic layer and contains a urethane resin. The urethane resin has a structure represented by structural formula (1) and a structure represented by structural formula (2) and/or a structure represented by structural formula (3) between two adjacent urethane bonds.



Document description JP2007-156435 A (Canon Inc.) 21 June 2007




JP2008-164915 A (Canon Inc.) 17 July 2008 JP2007-133113 A (Canon Inc.) 31 May 2007

No. of Claims: 6








[22] Date Filed: 4 July 2013

[54] Title: IMMUNOSUPPRESSANT FORMULATIONS


[72] Inventor(s): BOUILLOT, Philippe[FR]: REYNAUD, Emeric[FR]



[30] Priority Data: 11150431.2 07/01/2011 EP

[51] International Class 8: A61K 31/397; A61K 9/20

[57] Abstract:

The present invention relates to a solid phase pharmaceutical composition comprising one or more pharmaceutically acceptable excipients and an active pharmaceutical ingredient ("API") which is a compound of formula A1 or A2 or a pharmacologically acceptable salt, solvate or hydrate thereof, wherein the API is not exposed to a basic compound.



No. of Claims: 10








[22] Date Filed: 8 August 2013

[54] Title: MUTANT INTERLEUKIN-2 POLYPEPTIDES

[71] Proprietors(s): ROCHE GLYCART AG [CH]

[72] Inventor(s):

AST, Oliver[DE]: BRUENKER, Peter[DE]: FREIMOSER-GRUNDSCHOBER, Anne[CH]: HERTER, Sylvia[DE]: HOFER, Thomas U.[CH]: HOSSE, Ralf[DE]: KLEIN, Christian[DE]: MOESSNER, Ekkehard [DE]: NICOLINI, Valeria G.[ES]: UMANA, Pablo[CR]

[73] Assignee(s): ROCHE GLYCART AG [CH]

[74] Attorney / Agent: SYCIP SALAZAR HERNANDEZ AND GATMAITAN

[30] Priority Data: 11153964.9 10/02/2011 EP and 11164237.7 29/04/2011 EP

[51] International Class 8: A61K 39/395; A61K 47/48; C07K 14/55; C12N 15/26

[57] Abstract:

The present invention generally relates to mutant interleukin-2 polypeptides that exhibit reduced affinity to the a-subunit of the IL-2 receptor, for use as immunotherapeutic agents. In addition, the invention relates to immunoconjugates comprising said mutant IL-2 polypeptides, polynucleotide molecules encoding the mutant IL-2 polypeptides or immunoconjugates, and vectors and host cells comprising such polynucleotide molecules. The invention further relates to methods for producing the mutant IL-2 polypeptides or immunoconjugates, pharmaceutical compositions comprising the same, and uses thereof.



No. of Claims: 29








[22] Date Filed: 24 September 2013

[54] Title: PROCESS FOR THE PRODUCTION OF NICKEL CARBONATE

[71] Proprietors(s): VALE S/A [BR]

[72] Inventor(s): BERNI, Tiago Valentim[BR]: PEREIRA, Antonio Clareti[BR]: GUIMARÃES, Felipe Hilario[BR]

[73] Assignee(s): VALE S/A [BR]

[74] Attorney / Agent: VERA LAW (DEL ROSARIO RABOCA GONZALES GRASPARIL)

[30] Priority Data: 61/467,683 25/03/2011 US

[51] International Class 8: C01G 53/06

[57] Abstract:

The present invention refers to a process for production of nickel carbonate comprising the following steps: a) Preparing a magnesium salt solution; b) Contacting said solution with a stream of gaseous CO2, keeping pH between 4 and 10 and temperature between 0 and 100°C, during up to 5 hours; c) Contacting the mixture of step b) with a nickel sulphate solution, producing a mixture; d) Performing a separation of liquid and solid portions of said mixture; e) Feeding step a) with said liquid portion. This process recycles the reagent used for producing nickel carbonate and yields a final product that is easy to handle and transport.



Document description JPS61106422 (SUMITOMO METAL MINING CO) 24 May 1986 US3350167 (MCMULLEN WARREN H, et al) 31 OCTOBER 1967 JPH02172829 (SUMITOMO METAL IND, et al) 4 JULY 1990

No. of Claims: 5









[54] Title: FIRE RETARDANT, CIGARETTE PAPER WITH FIRE RETARDANT STRIP AND METHOD FOR MANUFACTURING CIGARETTE PAPER

[71] Proprietors(s): MUDANJIANG HENGFENG PAPER CO., LTD [CN]

[72] Inventor(s): WANG, Qicheng[CN]: LI, Jinsong[CN]: CHEN, Yuxiang[CN]: ZHAO, Maochen[CN]

[73] Assignee(s): MUDANJIANG HENGFENG PAPER CO., LTD [CN]

[74] Attorney / Agent: MANUEL C. CASES, JR. AND ASSOCIATES

[30] Priority Data: 201110393662.6 02/12/2011 CN

[51] International Class 8: D21H 19/44; D21H 27/22

[57] Abstract:

The present invention relates to a fire retardant, a cigarette paper with the fire retardant strip and the method for manufacturing the cigarette paper. The fire retardant comprises 10%-30% film-forming material by weight, 10%-30% filling material by weight and 40%-80% solvent. At least one fire retardant strip is provided on a front side and/or back side of the cigarette paper by printing a fire retardant, and the width of the fire retardant strip is 2-8mm. The present invention relates to the technology of manufacturing a cigarette paper with fire retardant strip, and strip coatings with a distance with each other are printed on the cigarette base paper so that gas permeability is reduced in the area of the strip coatings. When the cigarette naturally burns to the area of the fire retardant strip, the cigarette is self-extinguished as the fire retardant strip absorbs the heat and reduces the entry of the oxygen; when the cigarette burns to the area of the fire retardant strip, if the cigarette is smoked, the oxygen would enter into the cigarette, and the cigarette would continue to burn.






Document description CN1795770 (CHANGSHA CIGARETTE FACTORY [CN]) 05 July 2006 CN102094364 (YUNNAN TOBACCO SCI RES INST) 15 June 2011

No. of Claims: 9








[22] Date Filed: 1 October 2013

[54] Title: STABLE CREAMER COMPOSITION

[71] Proprietors(s): NESTEC S.A. [CH]

[72] Inventor(s): NAPOLITANO, Guillermo E.[US]: ERICKSON, Linda J[US]

[73] Assignee(s): NESTEC S.A. [CH]

[74] Attorney / Agent: SIGUION REYNA MONTECILLO AND ONGSIAKO LAW OFFICES

[30] Priority Data: 61/476,074 15/04/2011 US

[51] International Class 8: A23C 11/08

[57] Abstract:

The present invention relates to a creamer composition, e.g. for use for addition into a coffee beverage, with improved oxidative and physical stability. The creamer comprises oil with a high amount of oleic acids and a limited amount of linoleic acid and linolenic acid. The invention further relates to a method of producing the creamer, a beverage composition comprising the creamer and a method of producing a beverage composition.



Document description WO98/07329 A1 (NESTLE SA [CH]) 26 February 1998 US6426110 (BASA ALMARIO C [US]) 30 July 2002 US2001041211 (BEESON CHRISTINE A [US], et al) 15 November 2001

No. of Claims: 18








[22] Date Filed: 25 October 2013

[54] Title: NOVEL ANTIFUNGAL 5,6-DIHYDRO-4H-PYRROLO[1,2a][1,4]BENZO-DIAZEPINES AND 6H-PYRROLO[1,2-a][1,4]BENZODIAZEPINES SUBSTITUTED WITH HETEROCYCLIC DERIVATIVES

[71] Proprietors(s): JANSSEN PHARMACEUTICA NV [BE]

[72] Inventor(s): MEERPOEL, Lieven[BE]: MAES, Louis, Jules, Roger, Marie[BE]: DE WIT, Kelly[BE]: AUGUSTYNS, Koen, Jan, Ludovicus[BE]

[73] Assignee(s): JANSSEN PHARMACEUTICA NV [BE]

[74] Attorney / Agent: HECHANOVA & CO., INC.

[30] Priority Data: 11164960.4 05/05/2011 EP

[51] International Class 8: A61K 31/5513; C07D 487/04

[57] Abstract:

The present invention is concerned with novel antifungal 5,6-dihydro-4H-pyrrolo- [1,2-a][1,4]benzodiazepines and 6H-pyrrolo[1,2-a][1,4] benzodiazepines substituted with heterocyclic derivatives of Formula (I)

wherein R1, R2, R3, R4 and Het have the meaning defined in the claims. The compounds according to the present invention are active mainly against dermatophytes and systemic fungal infections. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.



Document description WO 0/34752 A1 (JANSSEN PHARMACEUTICA NV) 02 May 2002

No. of Claims: 20








[22] Date Filed: 18 December 2013

[54] Title: METHOD FOR REDUCING THE OCCURRENCE OF INFECTION IN YOUNG CHILDREN

[71] Proprietors(s): N.V. NUTRICIA [NL]

[72] Inventor(s): SIJBEN, Johannes Wilhelmus Christina[NL]: ALLES, Martine Sandra[NL]

[73] Assignee(s): N.V. NUTRICIA [NL]

[74] Attorney / Agent: CASTRO DE CLARO AND REYES LAW OFFICES

[30] Priority Data: PCT/NL2011/050449 22/06/2011 NL

[51] International Class 8: A23L 1/29; A23L 1/30; A23L 1/308; A61K 31/20; A61K 31/202; A61K 31/702; A61K 31/733; A61P 11/00

[57] Abstract:

The invention pertains to the use of a composition in reducing the number of infections episodes and the occurrence of infections in young children, said composition comprising: (a) long chain polyunsaturated fatty acids, wherein the amount of arachidonic acid is less than 0.06 gram per 100 gram fatty acid; and comprising, per 100 g fatty acids: (i) 0.3-0.6 gram docosahexaenoic acid; (ii) 0.2-0.4 gram eicosapentaenoic acid; and (b) between 1.5 and 2.5 gram indigestible oligosaccharides per 100 kcal, comprising: (i) 1.4-2 gram short-chain galactooligosaccharides; and (ii) 0.1 -0.5 gram long-chain fructopolysaccharides.



Document description EP 1714564 A1 (Nutricia NV) 25 October 2006 WO 2008/054192 A1 (Nutricia NV) 08 May 2008

No. of Claims: 12








[22] Date Filed: 20 December 2013

[54] Title: COMBINATION THERAPY COMPRISING A CDK4/6 INHIBITOR AND A PI3K INHIBITOR FOR USE IN THE TREATMENT OF CANCER


[72] Inventor(s): KIM, Sunkyu[US]: DOSHI, Shivang[IN]: HAAS, Kristy[US]: KOVATS, Steven[US]: HUANG, Alan Xizhong[US]: CHEN, Yan[US]



[30] Priority Data: 61/503,642 01/07/2011 US

[51] International Class 8: A61K 31/4439; A61K 31/519; A61K 31/535; A61P 35/00

[57] Abstract: A combination of a CDK4/6 inhibitor and a P3Kinase inhibitor for the treatment of cancer.



NONE

No. of Claims: 4








[22] Date Filed: 17 February 2014

[54] Title: NOVEL CRYSTAL FORM

[71] Proprietors(s): GLAXO GROUP LIMITED [GB]

[72] Inventor(s): LEE, Mei-yin[GB]

[73] Assignee(s): GLAXO GROUP LIMITED [GB]

[74] Attorney / Agent: E.B. ASTUDILLO & ASSOCIATES

[30] Priority Data: 61/530,104 01/09/2011 US

[51] International Class 8: A61K 31/4545; A61P 25/28; C07D 401/12

[57] Abstract: A novel crystalline form of a compound is disclosed.



Document description WO 02/30904 A1 (SMITHKLINE BEECHAM P.L.C.) 18 April 2002

No. of Claims: 56









[54] Title: METHODS OF SYNTHESIS AND PURIFICATION OF HETEROARYL COMPOUNDS

[71] Proprietors(s): SIGNAL PHARMACEUTICALS, LLC [US]

[72] Inventor(s):

HARRIS, Roy, L[US]: SAPIENZA, John[US]: SHEVLIN, Graziella[US]: PAPA, Patrick[US]: LEE, Branden, Gingsee[US]: PACKARD, Garrick[US]: ZHAO, Jingjing[CN]: JOKIEL, Patrick, Anthony[US]: MORTENSEN, Deborah[US]: RIGGS, Jennifer[US]: GAMBOA, Juan, Antonio[US]: BEAUCHAMPS, Marie, Georges[US]: KREILEIN, Matthew, Michael[US]: KOTHARE, Mohit, Atul[IN]: PERRIN-NINKOVIC, Sophie[FR]: PYE, Philip[GB]: LEONG, William, Wei-Hwa[US]: ELSNER, Jan[US]: CHOUDHURY, Anusuya[IN]

[73] Assignee(s): SIGNAL PHARMACEUTICALS, LLC [US]

[74] Attorney / Agent: HECHANOVA AND CO., INC.


[51] International Class 8: A61K 31/497

[57] Abstract:

Provided herein are methods to prepare Heteroaryl Compounds having the following structure: Formula (I) or Formula (II): wherein R1-R4 are as defined herein. The Heteroaryl compounds are useful for treating or preventing cancer, inflammatory conditions, immunological conditions, neurodegenerative diseases, diabetes, obesity, neurological disorders, age-related diseases, or cardiovascular conditions.



Document description WO 2008/051493 A2 (SIGNAL PHARM LLC [US]) 2 May 2008 (02.05.2008) WO 2010/062571 A1 (SIGNAL PHARM LLC [US]) 3 June 2010 (03.06.2010)

No. of Claims: 13









[54] Title: INHIBITORS OF NEDD8-ACTIVATING ENZYME

[71] Proprietors(s): MILLENNIUM PHARMACEUTICALS, INC. [US]

[72] Inventor(s): MCCARRON, Ashley Sue[US]: SELLS, Todd B.[US]: STIRLING, Matthew[GB]: STROUD, Stephen G.[US]

[73] Assignee(s): MILLENNIUM PHARMACEUTICALS, INC. [US]

[74] Attorney / Agent: ORTEGA BACORRO ODULIO CALMA & CARBONELL

[30] Priority Data: 61/526,830 24/08/2011 US

[51] International Class 8: A61K 31/505; A61K 31/519; A61P 35/00; C07D 487/02; C07D 487/04

[57] Abstract:

Disclosed are chemical entities which are inhibitors of Nedd8-activating enzyme (NAE), namely, the compound {(1S,2S,4R)-4-[(6-{[(1R,2S)-5-chloro-2-methoxy-2,3-dihydro-1H-inden-1-yl]amino}pyrimidin-4-yl)oxy]-2-hydroxycyciopentyl}methyl sulfamate and pharmaceutically acceptable salts thereof; solid state forms thereof; and prodrugs thereof. Also disclosed are methods of using the chemical entities to treat disorders such as cancer.



Document description WO 2010/132110 A1 (MILLENNIUM PHARMACEUTICALS. INC.) 18 November 2010 US 2007/0191293 A1 (LANGSTON, S. et al.) 16 August 2007 US 2008/0051404 A1 (CLAIBORNE, C. et al.) 28 February 2008

No. of Claims: 103








[22] Date Filed: 11 April 2014

[54] Title: APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE

[71] Proprietors(s): ABBVIE INC. [US]

[72] Inventor(s):

WANG, Le[US]: DOHERTY, George[US]: WANG, Xilu[US]: TAO, Zhi-Fu[US]: BRUNKO, Milan[US]: KUNZER, Aaron R[US]: WENDT, Michael D[US]: SONG, Xiaohong[US]: FREY, Robin[US]: HANSEN, Todd M[US]: SULLIVAN, Gerard M[US]: JUDD, Andrew[US]: SOUERS, Andrew[US]

[73] Assignee(s): ABBVIE INC. [US]

[74] Attorney / Agent: SYCIP SALAZAR HERNANDEZ AND GATMAITAN

[30] Priority Data: PCT/CN2012/078372 09/07/2012 CN and 61/547,165 14/10/2011 US

[51] International Class 8: C07D 417/14

[57] Abstract:

Disclosed are compounds having Formula (I) which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-xL protein.



Document description WO 2010/080503 A1 (GENENTECH INC [US]; INST MEDICAL W & E HALL [AU]; ABBOTT LAB [US] BAE) 15 July 2010 (15.07.2010) ALLISON M HUNTER ET AL; AN INTERNATIONAL JOURNAL ON PROGRAMMED CELL DEATH, KLUWER ACADEMIC PUBLISHERS, BO, vol. 12, no. 9, 19 June 2007 (19.06.2007)

No. of Claims: 198









[54] Title: IMMEDIATE RELEASE 4-METHYL-3-[[4-(3-PYRIDINYL )-2-PYRIMIDINYL ]AMINO]-N-[5-(4-METHYL-1H-1MIDAZOL-1YL)-3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE FORMULATION


[72] Inventor(s): BHARDWAJ, Upkar[IN]: BORDAWEKAR, Mangesh Sadashiv[IN]: COMFORT, Ann Reese[US]: LI, Ping[US]: LI, Shoufeng[US]: MAKAROV, Alexey[US]



[30] Priority Data: 61/559,281 14/11/2011 US

[51] International Class 8: A61K 9/00; A61K 9/20; A61K 9/28

[57] Abstract:

A solid dosage form of nilotinib is disclosed that comprises: (i) a core comprising 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl] benzamide or a pharmaceutically acceptable salt thereof and excipients; and (ii) at least one polymer, said polymer coating said core, wherein disintegration of said solid dosage form is delayed.



Document description US2010136097 (HYDE RODERICK A [US], et al) 3 June 2010 L. ZEMA ET AL, "Different HPMC viscosity grades as coating agents for an oral time and/or site-controlled delivery system: An investigation into the mechanisms governing drug release", JOURNAL OF PHARMACEUTICAL SCIENCES, (20070101), vol. 96, no. 6 KLEINEBUDDE P, "Roll compaction/dry granulation: pharmaceutical applications", EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, ELSEVIER SCIENCE PUBLISHERS B.V., AMSTERDAM, NL, (20040901), vol. 58, no. 2, 2004.04.014

No. of Claims: 88









[54] Title: CHILD RESISTANT BULK DOSE DISPENSING UNIT

[71] Proprietors(s): WYETH LLC [US]

[72] Inventor(s): ADLER, Ari Tao[US]: MCCAFFREY, Robert John[US]

[73] Assignee(s): WYETH LLC [US]

[74] Attorney / Agent: SYCIP, SALAZAR, HERNANDEZ AND GATMAITAN

[30] Priority Data: 12/728,482 22/03/2010 US

[51] International Class 8: B65D 50/04

[57] Abstract:

Child- resistant bulk dose dispensing packaging unit, and a method for opening the packaging unit, including a container and a lid engaged with the container. The container includes a reservoir, an aperture at a top end of the reservoir, and a protrusion extending from a surface of the container. The lid engages with the container and slides between a closed position and an open position. The lid includes a top wall, a side wall extending down from an outer edge of the top wall, and a post configured to engage the protrusion at a first position when the lid is closed so as to keep the lid closed. At least a portion of the post extends substantially parallel to the side wall at a distance from the side wall. Pressing the side wall inward places the post at a second position, wherein at the second position the post is disengaged from the protrusion.






Document description WO 2001/015998 A1 MAIETTA, Michael G. 08 March 2001 (08.03.2001) US 4 561 544 B1 REEVE, Randy F. 31 December 1985 (31.12.1985) US 5 082 137 B1 WEINSTEIN, Jack 21 January 1992 (21.01.1992) US 7 114 619 B2 DOUGLAS, Ellis et al. 03 October 2006 (03.10.2006)

No. of Claims: 2









[54] Title: A HYDROELECTRIC TURBINE SYSTEM

[71] Proprietors(s): OPENHYDRO IP LIMITED [IE]

[72] Inventor(s): IVES, James[IE]: DUNNE, Paul[IE]: CAWTHORNE, Simon[IE]

[73] Assignee(s): OPENHYDRO IP LIMITED [IE]

[74] Attorney / Agent: A.Q. ANCHETA & PARTNERS

[30] Priority Data: EP 11195054.9 21/12/2011 EP

[51] International Class 8: F03B 13/10; F03B 13/26; F03B 15/00; F03B 17/06

[57] Abstract:

The present invention provides a hydroelectric turbine system comprising a base mounted turbine for location on the seabed or the like, in order to generate electricity from the tidal flow of water through the turbine, the system incorporating a load bank, for example in the form of an array of resistive windings, to which the turbine can be selectively electrically connected in order to dissipate the electrical power as heat into the passing water.



Document description WO 2008/101805 A2 - AZ TECHNOLOGIES SAS [FR] - 28 August 2008 US 9,234,492 B2 - PAUL DUNNE, ET. AL. - 12 January 2016

No. of Claims: 14









[54] Title: ABSORBENT ARTICLE

[71] Proprietors(s): LIVEDO CORPORATION [JP]

[72] Inventor(s): TAKAHASHI, Yuki[JP]: AMANO, Emi[JP]: UDA, Tomohito[JP]

[73] Assignee(s): LIVEDO CORPORATION [JP]

[74] Attorney / Agent: SIGUION REYNA, MONTECILLO AND ONGSIAKO LAW OFFICES

[30] Priority Data: 2011-287454 28/12/2011 JP

[51] International Class 8: A61F 13/15; A61F 13/49; A61F 13/496

[57] Abstract:

A pants-type disposable diaper (1) includes a pair of strip projecting parts (13) projecting laterally from a line of connection between front and rear parts located respectively on the belly and back sides of a wearer, a first waist elastic member (443) joined to a first waist region (407) that is an upper part of a waist region (406) extending along a waist opening, and a second waist elastic member (444) joined to a second waist region (408) that is a lower part of the waist region (406). In a state in which an outer covering sheet (4) is elongated in a right-left direction, a first unit contractile force that is a contractile force in the right-left direction per unit width of the first waist region (407) in an up-down direction is smaller than a second unit contractile force in the second waist region (408). Accordingly, it is possible to suppress cutting in of the upper end portions of the pair of strip projecting parts (13) into the skin of the wearer and to prevent the disposable diaper (1) from slipping off in the up-down direction when being worn.






Document description JP2009125088 A / KAO CORP / 11 June 2009 JP2008543525 A / THE PROCTER & GAMBLE COMPANY / 04 January 2007

No. of Claims: 51








[22] Date Filed: 20 August 2014

[54] Title: SOLID ORAL FORMULATIONS AND CRYSTALLINE FORMS OF AN INHIBITOR OF APOPTOSIS PROTEIN


[72] Inventor(s): THAKUR, Jeewan[IN]: YANG, Dong[CN]: FENG, Lili[CN]



[30] Priority Data: 61/274,051 12/08/2009 US

[51] International Class 8: A61K 31/427; A61K 9/20; A61K 9/28; A61P 35/00; A61P 43/00; C07D 417/04

[57] Abstract:

The present disclosure relates to crystalline form of (S)-N-((S)-1- cyclohexyl-2-{(S)-2-[4-(4-fluoro-benzoyl)-thiazol-2-yl]-pyrrolidin-1-yl}-2-oxo-ethyl)- 2-methylamino-propionamide, salts and hydrates thereof. This disclosure also relates to solid oral formulation of (S)-N-((S)-1-cyclohexyl-2-{(S)-2-[4-(4-fluoro- benzoyl)-thiazol-2-yl]-pyrrolidin-1-yl}-2-oxo-ethyl)-2-methylamino-propionamide, pharmaceutically acceptable salts, solvates (including hydrates) thereof, as well as methods of treatment using the same.



Document description WO 2008/016893 A1 (NOVARTIS PHARMA GMBH [AT]) 7 February 2008 CAIRA M R: "CRYSTALLINE POLYMORPHISM OF ORGANIC COMPOUNOS"TOPICS IN CURRENT CHEMISTRY, SPRINGER, BERLIN, DE LNKO- 001:10.1007/3-540-69178-2_5, vol. 198, 1 January 1998, pages 163-208

No. of Claims: 22









[54] Title: BRUSHLESS DC MOTOR

[71] Proprietors(s): VASTECH HOLDINGS LTD. [GB]

[72] Inventor(s): MOSTOVOY, Alexander[IL]: SHLAKHETSKI, Victor[IL]: ZATSARININ, Sergey[RU]: SHOIKHEDBROD, Simen[IL]

[73] Assignee(s): VASTECH HOLDINGS LTD. [GB]

[74] Attorney / Agent: BUCOY POBLADOR & ASSOCIATES

[30] Priority Data: 218743 20/03/2012 IL

[51] International Class 8: H02K 1/27; H02K 21/12; H02K 5/167; H02K 7/08; H02K 7/116; H02P 6/14

[57] Abstract:

A brushless DC motor comprises a plurality of magnets positioned at a distance from one another on a circular structure, and a plurality of solenoids provided each around a static solenoid housing, wherein said solenoid housing is structured with a void portion through which said plurality of magnets can pass when the circular structure comprising said plurality of magnets rotates around its axis.



Document description US 6252317 B1 / SCHEFFER, Edward N., et al. / 26 June 2001 (26.06.2001) US 4291248 A / RAINBOLT, Michael A. / 22 September 1981 (22.09.1981) US 2009/0323208 A1 / KUROSAWA, Yuichi / 31 December 2009 (31.12.2009)

No. of Claims: 13









[54] Title: FLOOD CONTROL

[71] Proprietors(s): JOHNSON & NICHOLSON (M) SDN BHD [MY]

[72] Inventor(s): CHEW, Kien Ming[MY]: CHEW, Joon Yip[MY]

[73] Assignee(s): JOHNSON & NICHOLSON (M) SDN BHD [MY]

[74] Attorney / Agent: MUTIA AND TRINIDAD

[30] Priority Data: PI 2012000852 24/02/2012 MY

[51] International Class 8: E04H 9/14

[57] Abstract: The present invention provides a panel, a flood control assembly, a flood control device and a flood control barrier.



Document description US 5 645 373 A Jenkins, John T. 08 July 1997

No. of Claims: 6









[54] Title:

SHORT MESSAGE SERVICE MOBILE ORIGINATED/MOBILE TERMINATED WITHOUT MOBILE STATION INTERNATIONAL SUBSCRIBER DIRECTORY NUMBER (MSISDN) IN INTERNET PROTOCOL MULTIMEDIA SUBSYSTEM (IMS)

[71] Proprietors(s): NOKIA TECHNOLOGIES OY [FI]

[72] Inventor(s): WONG, Curt[US]: MUTIKAINEN, Jari[FI]

[73] Assignee(s): NOKIA TECHNOLOGIES OY [FI]

[74] Attorney / Agent: HECHANOVA AND CO. INC.

[30] Priority Data: 61/622,166 10/04/2012 US

[51] International Class 8: H04L 12/58; H04W 4/14

[57] Abstract:

Methods, apparatuses, and computer program products for submitting and/or delivering a SMS between user equipment without MSISDN are provided. One method includes storing the SIP-URI and IMSI for a device sending a SMS. The method may further include receiving a SMS from the sending device. In an embodiment, the TP-DA field of the MO-SMS is filled with value(s) that indicates the recipient UE is addressed without MSISDN, the R-URI is set to PSI, and the "to header" is set to the receiving device's SIP URI. The method may include retrieving the receiving device's SIP URI from the "to header," and querying the receiving device's HSS for the IMSI and routing information of the receiving device. The method may then include delivering the SMS to the receiving device directly or delivering the SMS to the receiving device via the SMSC.






Document description US2005002407 (A1) SHAHEEN et al. 06 January 2005

No. of Claims: 28









[54] Title: WINDER

[71] Proprietors(s): FUJI SEIKO CO., LTD. [JP] and FUJI SHOJI CO., LTD [JP]

[72] Inventor(s): NISHIDA, Kihachiro[JP]

[73] Assignee(s): FUJI SEIKO CO., LTD. [JP] and FUJI SHOJI CO., LTD [JP]


[30] Priority Data: NONE

[51] International Class 8: B21F 37/00; B29D 30/48

[57] Abstract:

A winding machine includes a first rotary body (12) to be rotated by a rotary shaft (11), and a second rotary body (16) to rotate on the same axis as the first rotary body (12) and at the same speed as the first rotary body (12). The winding machine further includes a cylinder (14) to open and close the first and second rotary bodies (12, 16) relative to each other. An outer circumferential surface of at least one of the first and second rotary bodies (12, 16) in a part where the first and second rotary bodies (12, 16) join is provided with a groove (20) in which a bead ring (B) is to be formed by winding a wire (W).



Document description US 5,108,538 A1 / KOKUBU, Satoru, et al. / 28 April 1992 US 2001/0023737 A1 / CARETTA, Renato, et al. / 27 September 2001

No. of Claims: 3








[22] Date Filed: 4 November 2014

[54] Title: METHOD, DEVICE AND COMPUTER STORAGE MEDIUM FOR CONTROLLING DISPLAYING

[71] Proprietors(s): TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED [CN]

[72] Inventor(s): LIU, Zhen[CN]

[73] Assignee(s): TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED [CN]

[74] Attorney / Agent: SAPALO VELEZ BUNDANG & BULILAN LAW OFFICES

[30] Priority Data: 201210143150.9 10/05/2012 CN

[51] International Class 8: A63F 13/00

[57] Abstract:

Examples of the present disclosure may provide a method, device or computer storage medium. The method may include: determining whether a registered first client terminal device and a registered second client terminal device are located at a same scene; sending information of the second client terminal device to the first client terminal device if the first client terminal device and the second client terminal device are located at the same scene, so that the first client terminal device displays the information of the second client terminal device in a visual list of the first client terminal device; and sending information of the first client terminal device to the second client terminal device, so that the second client terminal device displays the information of the first client terminal device in a visual list of the second client terminal device.



Document description US2011185290 A1, KIM et al., MOBILE TERMINAL AND CONTROLLING METHOD THEREOF, 28 July 2011 (28.07.2011) US2006167991 A1, HEIKES et al., BUDDY LIST FILTERING, 27 July 2006 (27.07.2006) US2010228560 A1, BALASAYGUN et al., PREDICTIVE BUDDY




LIST-REORGANIZATION BASED ON CALL HISTORY INFORMATION, 09 September 2010 (09.09.2010)

No. of Claims: 19

V21N43 PCT 2ND - Intellectual Property Office · Intellectual Property Center, 28 Upper McKinley...

Documents

Transcript of V21N43 PCT 2ND - Intellectual Property Office · Intellectual Property Center, 28 Upper McKinley...