Unit Two. Transforming principal of DNA Bacteria are capable of passing genetic information to...

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DNA Unit Two

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Transcript of Unit Two. Transforming principal of DNA Bacteria are capable of passing genetic information to...

Page 1: Unit Two. Transforming principal of DNA Bacteria are capable of passing genetic information to other bacteria.

DNAUnit Two

Page 2: Unit Two. Transforming principal of DNA Bacteria are capable of passing genetic information to other bacteria.

HISTORICAL DNA EXPERIMENTS

Page 3: Unit Two. Transforming principal of DNA Bacteria are capable of passing genetic information to other bacteria.

FREDRICK GRIFFITH (1928) Transforming principal of DNA

Bacteria are capable of passing genetic information to other bacteria

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PHEOBUS LEVENE (1929) Characterized different forms of nucleic acids: DNA and RNA

Determined nucleic acids are made of: adenine (A), thymine (T), cytosine (C), and guanine (G)

Page 5: Unit Two. Transforming principal of DNA Bacteria are capable of passing genetic information to other bacteria.

OSWALD AVERY (1944) Determined that DNA is the material in which genes and chromosomes are made.

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HERSHEY-CHASE EXPERIMENT (1952) Proteins were not the genetic material, DNA was

Page 7: Unit Two. Transforming principal of DNA Bacteria are capable of passing genetic information to other bacteria.
Page 8: Unit Two. Transforming principal of DNA Bacteria are capable of passing genetic information to other bacteria.

ROSALAND FRANKLIN (1951-1953) Research found picture of DNA X-ray crystallography Excluded from large discovery

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WATSON AND CRICK (1953) Discovered the “double helix” structure of DNA

Published paper without mentioning Rosalind Franklin (CONTROVERSY)

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ERWIN CHARGAFF (1959) Discovered three rules about DNA:

# of guanine equals # of cytosine # of adenine equals # of thymine # of A, T, C, G varies among species

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BACKBONE (EDGES) Deoxyribose sugar

Phosphate group

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NITROGENOUS BASES (MIDDLE)

Guanine Thymine

Cytosine Adenine


Microbes & Disease. Contents Bacteria Bacteria Culturing Bacteria Culturing Bacteria Commercial biotechnology Commercial biotechnology Bacterial Disease.

Microbes & Disease. Contents Bacteria Bacteria Culturing Bacteria Culturing Bacteria Commercial biotechnology Commercial biotechnology Bacterial Disease.

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