UNIT TEST-IPart-III Zoology GeneralPaper-IX2015Time: 3Hr F.M. 80

GROUP-A

1.Answer any SEVEN questions. 2X7=14

i.What do you mean by degeneracy of codon?

ii.What is v-onc and c-onc?

iii.What is do you mean by philadelphia chromosome?

iv.What is pRB? write its function.

v.What is Cot curve? what is its importance?

vi.What is mutagen? Give an example of chemical mutagen.

vii.Why tRNA are also called soluble RNA?

viii.What is BAC?

ix.What is MCS?

x.Differenciate symport and antiport.

xi.What is homopolymer tailing? Write its importance.

xii.

What is angiogenesis?

xiii.Differentiate carrier protein and channel protein.

xiv.What is hox gene? What is sxl gene?

GROUP-B

Answer any FIVE questions. 6X5=30

2.Describe Mendels law of inheritance with special reference to meiosis. [6]

3.Describe the nucleosome model. Describe chemi-osmotic hypothesis. [3+3=6]

4.Differentiate the followings (ANY TWO):a. Paracentric and Pericentric inversion. b. B-DNA and Z-DNA c. Normal cell and Tumor cell d. DNA POL-III and RNA-Pole. RAPD and RFLP [3+3=6]

5.What are the applications of DNA finger-printing. What is STR? [5+1=6]

6.Describe the method of t-DNA mediated gene transfer in plant. What is RNAi technology? [4+2=6]

7.What is CGN and TGN? Describe the role of golgi in cellular vesicular and cisternal transport. What is late endosome? [1+4+1=6]

8.What is wobble hypothesis? What is spliciosome? Describe the role of sigma factor in transcription. [2+2+2=6]

9.Write the role of tautomeric shift in mutation. What is transposon? What is missence mutation? [3+1+2=6]

GROUP-C

Answer any THREE questions. 12X3=36

10.What is holyday junction? How it is formed during crossing over? Describe the single strand break model of homologus recombination with suitable diagram. What is Robertsonian translocation. What is pleiotropy? [1+2+(4+3)+2+2=12]

11.Color blindness in humans is most commonly due to an X-linked recessive allele. Betty has normal vision, but her mother is color blind. Bill is color blind. If Bill and Betty marry and have a child together, what is the probability that the child will be color blind? Write the biochemical basis of ABO blood group? What is Bombay phenotype? [4+6+2=12]

12.What do you mean by genic sex determination? What is homogametic and heterogametic sex determination? Describe genic balance theory with a suitable experiment. [2+2+8=12]

13.What is operon? What is glucose effect? What is gratuitus inducer? Give example. Describe positive and negative regulation of lac-operon. [2+2+2+6=12]

14.In D. melanogaster, cherub wings (ch), black body (b), and cinnabar eyes (cn) result from recessive alleles that are all located on chromosome 2. A homozygous wild-type fly was mated with a cherub, black, and cinnabar fly, and the resulting F1 females were test-crossed with cherub, black, and cinnabar males. The following progeny were produced from the testcross:

(a) Determine the linear order of the genes on the chromosome (which gene is in the middle), (b) Calculate the recombinant distances between the three loci, (c) Determine the coefficient of coincidence and the interference for these three loci. What is homoallele? [5+3+2+2=12]

15.Write the function of topoisomerase. How nascent DNA is checked during replication for any fault and how it is repaired? Which enzyme(s) helps in this process? [2+8+2=12]

16.Write short notes on- a) Albinism, b) cri-du chat syndrome, c) -thalassemia, d) Down syndrome. [3x4=12]

1@DR. T.K.PAL