UNIFI Installation and Configuration GuideTurn on MSMQ Server 55 Configure the power options 56 ......

UNIFIUNIFI Installation and Configuration Guide

715004165 / Revision A

Copyright © Waters Corporation 2013All rights reserved

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General InformationCopyright notice

© 2013 WATERS CORPORATION. PRINTED IN THE UNITED STATES OF AMERICA AND IN IRELAND. ALL RIGHTS RESERVED. THIS DOCUMENT OR PARTS THEREOF MAY NOT BE REPRODUCED IN ANY FORM WITHOUT THE WRITTEN PERMISSION OF THE PUBLISHER.

The information in this document is subject to change without notice and should not be construed as a commitment by Waters Corporation. Waters Corporation assumes no responsibility for any errors that may appear in this document. This document is believed to be complete and accurate at the time of publication. In no event shall Waters Corporation be liable for incidental or consequential damages in connection with, or arising from, its use. For the most recent revision of this document, consult the Waters Web site (waters.com).

TrademarksACQUITY, ACQUITY UPLC, UPLC, Xevo, “THE SCIENCE OF WHAT’S POSSIBLE.”, and Waters are registered trademarks of Waters Corporation. UNIFI, Empower, and MassLynx are trademarks of Waters Corporation.

Microsoft, DirectX, Internet Explorer, Windows, and Windows 7 are registered trademarks of Microsoft Corporation in the United States and/or other countries.

NVIDIA is a registered trademark of NVIDIA Corporation in the US and other countries.

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Other trademarks or registered trademarks are the sole property of their respective owners.

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We seriously consider every customer comment we receive. You can reach us at [email protected].

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Waters contact information:

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Telephone and fax

From the USA or Canada, phone 800 252-4752, or fax 508 872 1990.For other locations worldwide, phone and fax numbers appear in the Waters Web site.

Conventional mail

Waters Corporation34 Maple StreetMilford, MA 01757USA

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http://www.waters.com/

PrefaceAudience and purpose

This guide is for those installing or upgrading UNIFI software. It provides the procedures required to install or upgrade and configure UNIFI software on a UNIFI workstation or a workgroup configuration.

Updated informationRefer to the Waters web site (Service & Support > Support > Support Library) for any updates to this guide.

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Table of Contents

General Information iii

Copyright notice iii

Trademarks iii

Customer comments iii

Contacting Waters iv

Preface v

Audience and purpose v

Updated information v

1 Introduction to UNIFI 11

Waters UNIFI software 11

Identify workstation hardware and software requirements 13

Identify workgroup hardware and software requirements 16

2 Configuring the Hardware 23

Preparing for UNIFI software 23

Selecting the site 23Environmental requirements 23Space considerations 24Power supply 25

Installing the hardware 25Install UNIFI workstation hardware 25Install UNIFI workgroup hardware 26Connect Ethernet instruments 26

3 Installing a UNIFI Workstation 29

Before you begin installing a workstation 29

Install UNIFI software on a workstation 29Before you begin 29Configure the Windows firewall settings 30

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Install UNIFI software on a workstation 32

Log on to the UNIFI portal 33

Activate UNIFI licenses 33Register and activate licenses 34View active licenses 35

Create a new administrator account 35

Install a Microsoft loopback network adapter 37

Remove UNIFI software from a workstation 38

4 Installing a UNIFI Workgroup 41

Before you begin installing a workgroup server 41Choose a database backup option 41Configure disk drives 43Create Windows application server role 44

Install UNIFI software on a workgroup server 45Before you begin 46Verify Windows hosts file information 46Enable the correct option for Windows updates 46Configure network discovery and file and printer settings 47Configure the network LAN 47Confirm regional settings 48Identify location for database backup copies 48Install UNIFI software on a workgroup server 48

Log on to the UNIFI portal 50

Activate UNIFI licenses 51Register and activate licenses 52View active licenses 53

Create a new administrator account 53

Install UNIFI software on a client 55Before you begin 55Turn on MSMQ Server 55Configure the power options 56Turn on network discovery and file and printer sharing settings 57Enable the correct option for Windows updates 57Verify connectivity between the client and workgroup server 57Install UNIFI software on a client 57

Install UNIFI software on a laboratory network device 58

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Before you begin 59Install UNIFI software on a custom laboratory network device 59Enable the correct option for Windows updates 59Turn on network discovery and file and printer sharing settings 60Turn on the Microsoft Message Queue Server 60Configure the power options 60Configure the Instrument LAN 61Configure the Windows firewall settings 62Install UNIFI software on a laboratory network device 62

Automate database backups to a network location 63Create an OS user account with the correct permissions 64Create a network share to store database backups 64Add credentials to automatically access the network share 65Create the OracleCRSToken Service and then manually set the password 66Stop the database and Oracle listener 66Stop services 67Grant permissions to the named user 67Start services 67Modify the database backup tasks to run as the local or domain user account 67Start the database and then restart the server 68Verify backups are copied to network location 68

Remove UNIFI software from a workgroup configuration 68

5 Managing the Database 71

Back up the workstation database 71Before you back up the workstation database 71Windows user groups 71Back up database to default location 72Back up database to a specified location 72Managing backup-related files 73

Restore the workstation database 73Before you restore the workstation database 74Restore database from a specified location 75

6 Verifying the installation 77

Verify installed files on a workstation 77

Verify installed files for a workgroup 78

7 Troubleshooting 81

Record a problem 81

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UNIFI Installation troubleshooting 81

A GMP Default Installations 87

Default settings overview 87

Data folders 89

Global policies 90Audit Trail Reasons global policy 90Date and time global policy 91Audit Trail global policy 92Timeout global policy 92User Account global policy 93Qualification global policy 93

Folder policies 94

Roles 96

Predefined reasons 100

Predefined meanings and comments 108

Custom fields 109

User account 109

Event properties 110

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1 Introduction to UNIFI

Contents:

Waters UNIFI software 11Identify workstation hardware and software requirements 13Identify workgroup hardware and software requirements 16

Waters UNIFI softwareThe Waters UNIFI workstation configuration consists of the following components:

Workstation components

Purpose

UNIFI soft-ware

Control instruments and devices to acquire, analyze, process, and report data, and to perform other information management functions.

Database Stores the metadata or descriptive information about the samples run (processed results, sample identifiers, methods, and reports), in a rela-tional database management system (RDBMS). Raw data are also stored in the database.

Workstation Runs on the Microsoft® Windows® 7 Professional SP 1, 64-bit operating system (OS).

Waters instru-ment systems

Groups of chromatographic instruments and mass spectrometers that you create to form an instrument system. These systems, which connect to a workstation, perform chromatographic (LC) and mass spectrometric (MS) analyses. For example, a UNIFI instrument system based on Waters UPLC tech-nology can include solvent manager, sample manager, column manager, one or more detectors, chromatographic columns, and an e-SAT/IN module. For MS analyses, its configuration can include a Xevo mass spec-trometer. The number of instrument systems supported by a UNIFI workstation depends on the type of detector included in the instrument system.Number of instrument systems supported by a UNIFI workstation: l One instrument system that contains a quadruple mass spectrometer,

or l One instrument system that contains a TOF (time of flight) mass spec-

trometer, or l Two instrument systems that contain optical detectors, such as a PDA

or TUV

The Waters UNIFI workgroup configuration consists of the following components:

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Workgroup components

Purpose

UNIFI soft-ware

Control instruments and devices to acquire, analyze, process, and report data, and to perform other information management functions.

Workgroup server

Stores the metadata or descriptive information about the samples run (processed results, sample identifiers, methods, and reports), in a rela-tional database management system (RDBMS). Raw data are also stored in the database. The Oracle Enterprise Manager (OEM) allows for monit-oring and some management functions of the UNIFI database. UNIFI soft-ware also supports Oracle® Automatic Storage Management (ASM) for disk management (data files, redo logs, control files) on physical internal or external disks like a storage area network (SAN) disk.

Laboratory network devices

Collect all data acquired by Waters instrument systems. Recommendation: Procure a pre-configured LND from Waters. Doing so, is more efficient than performing the labor-intensive work of configuring a computer to serve as an LND.The number of online instrument systems per LND depends on the type of detector included in the instrument system.Maximum number of online instrument systems per LND: l One instrument system that contains a quadruple mass spectrometer,

or l One instrument system that contains a TOF (time of flight) mass spec-

trometer, or l Two instrument systems that contain optical detectors, such as a PDA

or TUV

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Workgroup components

Purpose

Waters instru-ment systems

Groups of chromatographic instruments and mass spectrometers that you create to form an instrument system. These systems, which connect to laboratory network devices, perform chromatographic (LC) and mass spec-trometric (MS) analyses. For example, a UNIFI instrument system based on Waters UPLC tech-nology can include solvent manager, sample manager, column manager, one or more detectors, chromatographic columns, and an e-SAT/IN module. For MS analyses, its configuration can include a Xevo mass spec-trometer. The number of instrument systems supported by a UNIFI workgroup depends on the type of detector included in the instrument system. Your instrument systems can include a combination of mass spectrometers and optical detectors such as PDAs or TUVs, but cannot include a combination of quadruple and TOF (time of flight) mass spectrometers. Number of instrument systems supported by a UNIFI workgroup: l Four instrument systems that contains a quadruple mass spec-

trometer, or l Two instrument systems that contains a TOF (time of flight) mass spec-

trometer, or l Six instrument systems that contain optical detectors, such as a PDA

or TUVRefer to the example below this table for the maximum number of instru-ment systems supported by a UNIFI workgroup.

Client computers

Access UNIFI software installed on the workgroup server.

Local area network (LAN)

Interconnects all devices that comprise a workgroup. You cannot use a WAN (wide area network) configuration.

Identify workstation hardware and software requirementsThe following table describes the recommended hardware, software, and operating system requirements for a UNIFI workstation that includes an instrument system comprised of a quadruple mass spectrometer or an optical detector, such as a PDA or TUV.

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Identify workstation hardware and software requirements

Recommended workstation configuration:

Component Requirement

Application software UNIFI v1.7 software

OS Windows 7 Professional SP1 (64-bit) with MSMQ Server enabled.

Processor Intel® Xeon® E5-2620 Processor (2.0 GHz)

Random-access memory (RAM)

16 GB

Hard disk drive Two x 2 TB SATA 7.2K hard drives Tip: The installer requires a minimum of 40 GB.

Optical drive DVD

Virtual memory Let Windows manage the virtual memory.

Monitor A minimum resolution of 1024 x 768, but the recommended resol-ution is 1900 x 1200.

Network adapter card Two 10/100/1000 GB network adapter ports

Video card Discrete video card, with a minimum of 1 GB of memory (DirectX 11 or higher compatible.)

The following table describes the minimum hardware, software, and operating system requirements for a UNIFI workstation that includes an instrument system comprised of a quadruple mass spectrometer or an optical detector, such as a PDA or TUV.

Minimum workstation configuration:



OS Windows 7 Professional SP1 (64-bit), with MSMQ Server enabled.

Processor Intel® Xeon® E5507 (2.26 GHz)


12 GB

Hard disk drive Two 1TB 7.2K SATA driveTip: The installer requires a minimum of 40 GB.

Optical drive DVD




Video card Discrete video card, with a minimum of 512 MB of memory (DirectX 11 or higher compatible.)

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The following table describes the recommended and minimum hardware, software, and operating system requirements for a UNIFI workstation that includes a TOF (time of flight) mass spectrometer.

Minimum and recommended workstation configuration:




Processor Dual Intel® Xeon® E5-2620 processors (2.0 GHz)


64 GB

Hard disk drive One x 256GB 2.5-inch SATA Solid State diskTwo x 2TB SATA 3.5-inch 7.2K hard drivesTip: The installer requires a minimum of 40 GB.

Optical drive DVD




Video card Discrete video card, with a minimum of 1 GB of memory (TESLA GPU card.)

GPU card GPU-based processing is supported. Supported cards: NVIDIA Tesla GPU C2050, C2070, and C2075.Recommended card: NVIDIA Tesla GPU C2075.

The following table describes the recommended hardware, software, and operating system configuration required for a process-only workstation.

Recommended process-only workstation configuration:




Processor Intel® Xeon® E5-2620 Processor (2.0 GHz)


16 GB

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Identify workstation hardware and software requirements


Hard disk drive Two x 2 TB SATA 7.2K hard drives Tip: The installer requires a minimum of 40 GB.

Optical drive DVD




Video card Discrete video card, with a minimum of 1 GB of memory (DirectX 11 or higher compatible.)

The following table describes the minimum hardware, software, and operating system config-uration required for a process-only workstation.

Minimum process-only workstation configuration:




Processor Intel® CoreTM i5


16 GB

Hard disk drive A single 1 TB 7.2K SATA drive with a minimum of 250 GB free space on the C drive.Tip: The installer requires a minimum of 40 GB.

Optical drive DVD



Network adapter card Single GB 10/100/1000 network adapter card

Video card Discrete video card with a minimum of 512 MB of memory

Identify workgroup hardware and software requirementsA 100/1000, Ethernet high-speed network connection must connect the client, laboratory network device, and workgroup server in a local area network (LAN) configuration.

Restriction: You cannot use a WAN (wide area network) configuration.

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The following table describes the recommended and minimum hardware, software, and operating system requirements for a UNIFI client in a workgroup configuration that includes a quadruple mass spectrometer or an optical detector, such as a PDA or TUV.

Recommended and minimum configuration for a UNIFI client:


Application soft-ware

UNIFI v1.7 software

OS Windows 7 Professional SP1 (64-bit)

Processor Recommended: Intel® CoreTM i5 Processor (3.30 GHz)Minimum: Intel® CoreTM Duo Processor (2.66 GHz)


Recommended: 8 GB Minimum: 4GB

Hard disk drive A minimum of 250 GB free space.Tip: The installer requires a minimum of 11 GB.

Optical drive DVD

Virtual Memory Let Windows manage the virtual memory.

Monitor A minimum resolution of 1024 ×768, but the recommended resolution is 1900 × 1200.

Network adapter Card

One GB network adapter port

Video card Embedded video card with a minimum of 512 MB of memory. The video card must be DirectX 11 or higher compatible.

The following table describes the recommended and minimum hardware, software, and operating system requirements for a UNIFI client in a workgroup configuration that includes a TOF (time of flight) mass spectrometer.

Recommended and minimum configuration for a UNIFI client:



UNIFI v1.7 software

OS Windows 7 Professional SP1 (64-bit)

Processor Intel® CoreTM i5 Processor (3.30 GHz)


16 GB

Hard disk drive A minimum of 250 GB free space on the C drive.Tip: The installer requires a minimum of 11 GB.

Optical drive DVD

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Identify workgroup hardware and software requirements


Virtual Memory Let Windows manage the virtual memory.

Monitor A minimum resolution of 1024 ×768, but the recommended resolution is 1900 × 1200.

Network adapter Card

One GB network adapter card

Video card Embedded video card with a minimum of 512 MB of memory. The video card must be DirectX 11 or higher compatible.

Recommended and minimum configuration for a UNIFI laboratory network device:



OS Windows 7 Embedded Standard SP1 (for the LND provided by Waters Corporation only).Windows 7 Professional SP1 (64-bit) with MSMQ Server enabled

Processor Intel® CoreTM 2 Duo Processor E8400 (3.0 GHz, 1333 MHz FSB)


8 GB

Virtual memory Double the amount of physical RAM

Hard disk drive A minimum of 250 GB of free space ensures enough space in the event data buffering occurs on the LND.Tip: The installer requires a minimum of 11 GB.

Optical drive DVD

Network adapter card

Two 10/100/1000 GB network ports

The following table describes the recommended and minimum hardware, software, and operating system requirements for a UNIFI workgroup server in a workgroup configuration that includes a quadruple mass spectrometer, or an optical detector, such as a PDA or TUV.

Recommended and minimum configuration for a UNIFI workgroup server:



UNIFI v1.7 software

OS Windows Server 2008 R2 Standard SP1 (64-bit)

Processor Two Intel Xeon E5640 Processor at 2.66 GHz


24 GB

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Virtual memory Twice the amount of RAM.

Disk drives Two 600 GB 10K SAS drives RAID 1 (mirrored) for the operating system.Tip: The installer requires a minimum of 40 GB.

Server storage Data drives: l 900 GB 10K SAS drives l RAID 1 l 1x hot spareFRA (Fast Recovery Area) drives: l 1 TB 7.2K NL SAS drives l RAID 5 (striped with parity) l 1x hot spare

Oracle Data Group and FRA hard disk drives

Waters recommends: During software installation, select the Oracle ASM External Redundancy option.For instrument systems that include quadruple mass spectrometers or optical detectors these drives: l 6 data group drives, which provide 2.7 TB of usable space. l 6 FRA drives, which provide 5 TB of usable space.

Tips: l The FRA storage size is based on the requirement that storage must

be large enough to accommodate two full database backups. The old backup is not deleted until the new backup is complete.

l RMAN backups are compressed by approximately 33%. As your data group grows, the FRA storage location must grow accordingly.

Calculation: Data group size x 2 database backups x 0.66 compression rate.

Optical drive DVD - Read/Write

Monitor A minimum resolution of 1024 × 768Recommended: 1900 × 1200.


Dual port gigabit, network server adapter, NIC card

The following table describes the recommended and minimum hardware, software, and operating system requirements for a UNIFI workgroup server in a workgroup configuration that includes a TOF (time of flight) mass spectrometer.

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Recommended and minimum configuration for a UNIFI workgroup server:



UNIFI v1.7 software

OS Windows Server 2008 R2 Standard SP1 (64-bit)

Processor Two Intel Xeon E5640 Processor at 2.66 GHz


24 GB

Virtual memory Twice the amount of RAM.

Disk drives Two 600 GB 10K SAS drives RAID 1 (mirrored) for the operating system.Tip: The installer requires a minimum of 40 GB.

Server storage Data drives: l 900 GB 10K SAS drives l RAID 1 l 1x hot spareFRA (Fast Recovery Area) drives: l 1 TB 7.2K NL SAS drives l RAID 5 (striped with parity) l 1x hot spare

Oracle Data Group and FRA hard disk drives

Waters recommends: During software installation, select the Oracle ASM External Redundancy option.For instrument systems that include quadruple mass spectrometers or optical detectors these drives: l 16 data group drives, which provide 7.2 TB of usable space. l 12 FRA drives, which provide 11 TB of usable space.

Tips: l The FRA storage size is based on the requirement that storage must

be large enough to accommodate two full database backups. The old backup is not deleted until the new backup is complete.

l RMAN backups are compressed by approximately 33%. As your data group grows, the FRA storage location must grow accordingly.

Calculation: Data group size x 2 database backups x 0.66 compression rate.

Optical drive DVD - Read/Write

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Monitor A minimum resolution of 1024 × 768Recommended: 1900 × 1200.


Dual port gigabit, network server adapter, NIC card

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2 Configuring the Hardware

Contents:

Preparing for UNIFI software 23Selecting the site 23Installing the hardware 25

Preparing for UNIFI softwareExcept for a UNIFI workstation, all configurations require a pre-existing local area network (LAN), so that the Workgroups system can function. Waters personnel do not install network cables.

To install and activate Waters licenses and options, you must use a computer connected to the Internet. Note, however, that this computer need not be the one running UNIFI software.

Before installing any hardware or software, it is wise to perform a full backup of your hard drives (see instructions provided by the manufacturer of your computer). After the install-ation, back up UNIFI data regularly.

Selecting the siteLocate the UNIFI system in a clean area that is free from shock, vibration, and extremes of temperature and humidity.

Environmental requirementsInstall theUNIFI system in a draft-free position protected, away from excessive amounts of dust. Protect equipment from direct sunlight and heating and air conditioning vents.

Temperature and humidity

The UNIFI system can operate within the following temperature and humidity ranges:

l Maintain an ambient temperature of between 15 and 28 °C

l Ensure the ambient humidity does not exceed 80% relative humidity, non-condensing

Acceptable temperature and humidity ranges vary according to the model of the computer and printer.

Vibration

Do not install the UNIFI system near heavy machines such as compressors and generators, which can create excessive floor vibration.

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Magnetic fields

If the UNIFI system includes a mass spectrometer, position the system away from strong magnetic fields such as those generated by NMR systems or magnetic-sector mass spec-trometers.

Radio emissions

Install the UNIFI system in an environment where radio frequency (RF) emission from surrounding sources is minimal. Possible sources of RF emission include RF-linked alarm systems, mobile telephones, and hand-held transmitters.

Exhaust outlets

If a UNIFI system includes a chromatographic system or mass spectrometer, to avoid expos-ure to solvent vapors, refer to the system's site preparation guide for exhaust requirements.

Space considerationsAllow sufficient bench space for the UNIFI personal workstation, Workgroup, or client computers (keyboard, monitor, system unit, and printer), as recommended in the docu-mentation supplied with the computer.

For workstation installations, place computers on a lab bench or a desktop near the system instruments to enable control and tuning of the chromatography or MS system. The total bench space you require depends on the number of devices you plan to configure (pumps, detectors, autosamplers, and so on).

For Workgroup installations, place the laboratory network device and the client computer on a lab bench or a desktop near the system modules. Locate the workgroup server in a separ-ate server room managed by IT personnel. Other client computers can be located anywhere on the network or domain.

Ventilation

Ensure the ventilation slots on all system modules are not blocked. Allow at least 15 cm of space on all sides of each module to ensure adequate air flow.

Cable lengths

Arrange the components of a chromatographic system to minimize cable lengths. Use optimal lengths to ensure proper signal transmission.

All Waters instruments are shipped domestically with a 2.3-m power cord connected to the rear of the chassis. International power cords are 2.5 m. For the data system (computer, monitor, keyboard, mouse), if required, you can use extension cables from a PC vendor.

Instrument arrangement

Place the workstation or client computer (computer, monitor, keyboard, mouse) or the labor-atory network device (computer only) on a laboratory bench close to the system modules. If

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the UNIFI system includes a mass spectrometer, locate the data system within 5 m of the mass spectrometer, to allow connection of the communication cables.

For information on the best arrangement of your UNIFI system and connected instruments, consult your Waters technical service representative.

Power supplyAll UNIFI system components require a dedicated, earthed (grounded) power source. Ensure that the power supply cables of the system modules easily reach the electrical outlets connected to a common ground.

Consider using a line conditioner or an uninterruptible power supply (UPS), for optimum long-term input-voltage stability.

If a UNIFIsystem includes a chromatographic system or a mass spectrometer, refer to its site preparation guide for the following power requirements:

l Power supply

l Electrical transformers

l Uninterruptible power supply

Installing the hardware

Install UNIFI workstation hardwareThe UNIFI workstation supports an optional, second, interface card for Ethernet instru-ments.

If you install UNIFI software on a computer that is not included in a network, you must install a Microsoft loopback network adapter (see "Install a Microsoft loopback network adapter").

To set up a UNIFI workstation:

1. Unpack and place the workstation in its final location.

2. Connect the keyboard, mouse, and monitor to the workstation.

3. Ensure the voltage-selection switch on the PC tower is set to the correct voltage for the laboratory supply.

4. To install other computer peripherals, such as a printer, see the installation doc-umentation supplied with the device.

5. Switch on the PC, monitor, and peripheral devices.

6. Login to the Microsoft Windows 7 desktop using the administrator account with the password "waters".

7. If required, change the PC name and domain, and then connect to your facility's net-work.

8. If applicable, connect the Ethernet devices (see "Connect Ethernet instruments").

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Install UNIFI workgroup hardwareThe UNIFI workgroup system comprises a server, one or more clients, and one or more laboratory network devices. Each computer in the workgroup system requires at least one network interface card. Ethernet instruments in a UNIFI workgroup connect to a laboratory network device.

To set up a UNIFI workgroup server:

1. Unpack and place the server in the desired location.

2. Connect the keyboard, mouse, and monitor to the server.

3. To install other computer peripherals, such as a printer, refer to the installation doc-umentation supplied with the device.

4. Ensure that the network interface card is installed in the server.

To set up a UNIFI workgroup client:

1. Unpack and place the client in the desired location.

2. Connect the keyboard, mouse, and monitor to the client.

3. Ensure that the network interface card is installed in the client.

4. Repeat step 1 through step 3 for each client in the workgroup system.

5. Connect the client to the network.

To set up a UNIFI laboratory network device:

1. Unpack and place the laboratory network device in its final location.

2. Ensure that the network interface card is installed in the laboratory network and set up correctly.

3. Ensure that a second network interface card is present.

4. Connect the laboratory network device to the network.

5. Connect the Ethernet devices (see "Connect Ethernet instruments").

Connect Ethernet instrumentsEthernet instruments connect directly to a network interface card (NIC) installed in a work-station or laboratory network device. If you are connecting multiple Ethernet instruments, use a Waters-supplied switch to connect the Ethernet cable from the workstation or labor-atory network device to the switch. Then plug each instrument into the switch.

The NIC used for instrument connections is separate and apart from the NIC used to commu-nicate with your facility's network.

Multiple Ethernet connections require crossover cables to control a mass spectrometer through a network switch. In addition, resetting the link speed and duplex properties of an NIC to Auto Detect can be necessary. In both cases, if you are using more than one NIC, you can modify the settings for a second NIC using the DHCP wizard after you install UNIFI soft-ware.

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See the Ethernet Getting Started Guide for more information on connecting and configuring Ethernet devices.

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3 Installing a UNIFI Workstation

Contents:

Before you begin installing a workstation 29Install UNIFI software on a workstation 29Log on to the UNIFI portal 33Activate UNIFI licenses 33Create a new administrator account 35Install a Microsoft loopback network adapter 37Remove UNIFI software from a workstation 38

Before you begin installing a workstationBefore you begin the installation, complete these tasks:

l Ensure the workstation meets the minimum requirements for hardware and software.

l Verify that the disk drive has enough space to install UNIFI software.

l If installing UNIFI software on a computer not included in a network, install the Microsoft loopback adapter.

l Close all other applications and restart the workstation.

See also:

l Identify workstation hardware and software requirements

l Install a Microsoft loopback network adapter

Install UNIFI software on a workstationThe Waters UNIFI installation wizard guides you through the installation process. Allow approximately 30 minutes to complete the installation.

Caution: After you install UNIFI software on a workstation, Waters recommends that you do not change the IP address or computer name of the workstation. Changing either of these may render UNIFI software unusable.

Before you beginBefore you install UNIFI software on a workstation, perform these tasks:

l Configure the instrument LAN

l Configure the Windows firewall settings

l Turn on MSMQ Server

l Enable the correct option for Windows updates

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l If you are using real-time virus scanning, exclude all UNIFI–related folders and their sub-directories. Some real-time virus scanners mistake normal UNIFI software func-tionality for virus activity, causing data buffering problems.

Configure the Instrument LAN

You must configure the power management settings and assign the IP address for the Instru-ment LAN to communicate with the instruments. Log on to the workstation as the local admin-istrator.

l Configure the power management settings and rename the connection to Instrument LAN

l Configure IP address

To configure the power management settings:

1. Click Start > Control Panel > Network and Internet > Network and Sharing Center > View network status and tasks > Change adapter settings.

2. Right-click on Local Area Connection, select Rename, and type Instrument LAN.

3. Right-click Instrument LAN, and then click Properties. If you are instructed to enter an administrator password or confirmation, do so.

4. On the Networking tab, click Configure.

5. On the Power Management tab, clear the "Allow the computer to turn off this device to save power" checkbox, and then click OK.

To configure the IP address:


2. Right-click Local Area Connection, Instrument LAN, and then click Properties.

3. On the Networking tab, clear the Internet Protocol Version 6 (TCP/IPv6) checkbox.

4. Select Internet Protocol Version 4 (TCP/IPv4), and then click Properties.

5. In the Internet Protocol Version 4 (TCP/IPv4) Properties dialog box, click "Use the fol-lowing IP address".

6. Assign the following IP address and Subnet mask, and then click OK:

l IP address: 192.168.0.1

l Subnet mask: 255.255.255.0

Result: The assigned setting is saved for the local area connection, instrument LAN.

Configure the Windows firewall settingsFor a laboratory network device, you must configure Windows firewall settings to turn off the Windows firewall for the Instrument LAN (public network).

Tip: For the instruments to communicate with the LND, you must configure the LND's Windows firewall settings.

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To configure the Windows firewall settings:

1. Click Start > Control Panel > Network and Internet > Network and Sharing Center > Windows Firewall.

Alternative: Right-click Network from the desktop and then select Properties > Windows Firewall.

2. On the Windows Firewall page, click "Turn Windows Firewall on or off".

3. On the Customize Settings page, perform these tasks, and then click OK:

l Click "Turn on Windows Firewall" for the "Home or work (private) location set-tings".

l Click "Turn off Windows Firewall (not recommended)" for the "Public network loc-ation settings".

Turn on Microsoft Message Queue Server

You must turn on MSMQ Server to run the installation wizard. When you fail to do so, the wizard closes.

To turn on MSMQ:

1. Click Start > Control Panel > Programs > Programs and Features.

2. Click the option "Turn Windows features on or off".

3. In the Windows Features dialog box, expand Microsoft Message Queue (MSMQ) Server, and then expand Microsoft Message Queue (MSMQ) Server Core.

4. Select MSMQ HTTP Support and MSMQ Triggers.

Tip: Do not select MSMQ Active Directory Domain Services Integration and Mult-icasting Support.

5. Click OK, and then wait while the features are configured.

Enable the correct option for Windows updates

You must select the option "Check for updates, but let me choose whether to download them".

To specify the correct option for Windows updates on a client:

1. From Windows Control Panel, click "System and Security".

2. From the System and Security page, click "Windows Update".

3. From the Windows Update page, click "Change settings" page.

4. In the Important updates section of the Change Settings page, select "Check for updates, but let me choose whether to install them" option, and then click OK.

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Install UNIFI software on a workstation

Install UNIFI software on a workstationWhen you install UNIFI software on a workstation, the language installed is based on the workstation's operating system language. If the workstation's operating system is English, the software is installed in English. You cannot install the Japanese version of UNIFI soft-ware, on an English workstation.

Requirement: You must have unrestricted local Windows administrator or equivalent priv-ileges to install UNIFI v1.7 software.

To install the UNIFI software:

1. Insert the UNIFI DVD into your computer's DVD drive.

Tip: If the installer does not automatically open, open Window's Explorer, browse to the DVD drive, and double-click Setup.exe.

2. From the installation menu, click "Install UNIFI on a workstation".

3. On the Waters Software License Agreement page, read the agreement, click "I accept the terms of the license agreement", and then click Next.

4. On the Select an Installation Drive page, select a drive other than the OS (operating system) drive to install the software on.

5. On the Import Database page, perform one of these operations:

l If you are migrating the database to this computer, click Yes, and then specify the location of the database file that you previously exported.

l If you are performing a new installation, and not migrating the database, click Next.

6. On the Configure UNIFI policy and audit trail settings page, perform one of these oper-ations:

l To comply with GxP guidelines and regulations, click "Configure settings for a reg-ulated environment (GxP)".

l To configure settings for a unregulated environment, click "Configure settings for a non-regulated environment".

See also: Appendix A for system policy and audit trail settings for a regulated and unregulated environment.

7. On the Ready to Install page, click Install.

8. On the Confirmation page, click Finish

Tip: If the installation failed, click the link to open the Waters Installation Summary. If the soft-ware was not successfully installed, submit a request for Waters technical support at this web address: http://www.waters.com/irequest. If you close the installation wizard and you want to open the installation log, browse to C:\Windows\WatersInstallationSummary.

See also: For instructions on how to qualify the software, see the Workstation Qualification Protocol which is available on the UNIFI Qualification media. For more information about qualification, refer to the "Qualification Overview" document on this media.

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http://www.waters.com/irequest

After you install UNIFI software on a workstation

After you install UNIFI software on a workstation, you can install a UNIFY print driver; however, you must install UNIFI software first and then the UNIFY print driver. For instruc-tions on how to install the UNIFY print driver, see the NuGenesis 8 Installation and Config-uration Guide.

Log on to the UNIFI portalAfter you install UNIFI, you must log on to the UNIFI portal to register the software and activ-ate your licenses.

Tip: When you restart the workstation, wait at least five minutes before logging on to UNIFI software to allow time for Waters Service Host to restart.

You can have 3 open Portal sessions open on a workstation.

To log on to UNIFI software:

1. On your desktop, double-click UNIFI Portal .

2. In the Login dialog box, type "administrator" in both the User name and password fields.

3. On the Welcome page, click Administration, and then click Licensing, where you register and activate product licenses.

Activate UNIFI licensesUse the Waters Licensing Management System to activate or deactivate the purchased soft-ware's product licenses and options. Waters' licenses apply to a UNIFI system and user accounts. You can assign and revoke UNIFI named-user licenses to user accounts as needed.

Workstation license and options:

License type

Required Definition

System base

Yes There are two types of system base licenses: workstation and process-only. Both licenses configure the database as a UNIFI work-station and include 5 named-user licenses, but the process only-base license doesn't allow data acquisition.

UNIFI named-user

No If you want to support more than five active users, you can activate additional named-user licenses. Named-user licenses are required for users to log on to the software.

Large molecule

No If your instrument system includes a time of flight (TOF) mass spec-trometer, this license is required to perform mass spectrometry-based analysis.

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Log on to the UNIFI portal

License type

Required Definition

Small molecule

No If you want to process the data using the Dealkylation, MassFrag-ment and IsoScore tools, this license is required.

Waters scientific library

No If you want to import a Waters scientific library, the appropriate library license is required. Tip: You can import and export your own scientific library.

Qualification licenses:

License type

Required for qual-ification

Definition

Qualification- software

Yes If you want to qualify the workstation, you must purchase a license for the workstation.

Qualification- instrument

Yes To qualify instruments on a workstation, you must activate these licenses: l The UNIFI Instrument Qualification Module license is

required for each LC instrument included in an instru-ment system.

l The UNIFI Instrument Qualification Standard Tech-nology MS license is required for each Xevo TQ , Xevo TQD, Xevo TQ-S mass spectrometer.

l The UNIFI Instrument Qualification High Technology MS license is required for Xevo G2 TOF, Xevo G2 -S TOF, Xevo G2-S Q TOF mass spectrometers.

l The UNIFI Instrument Qualification Accessory license is required for each instrument accessory module.

After you install UNIFI software, you must register, activate, and assign UNIFI named-user licenses to users by using the licensing wizard in UNIFI software and the Internet as follows:

l Create a software registration file using the licensing wizard.

l Submit the software registration file to the Waters License Activation Center Web site, and receive a license activation file.

l Activate your licenses and options using the licensing wizard and the license activation file.

Register and activate licensesYou must register and activate the UNIFI base license to access UNIFI software. You can activate licenses other than the base license at the same time or after activating the base license, but not before doing so.

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Pre-requisite: To complete the licensing process, you must have purchased UNIFI licenses from Waters and obtained a serial number for each purchased license.

To register licenses:

1. On the Licensing Home page, click Register Software.

2. On the Request Software page, perform these tasks, and then click Next:

l Type a new name for the software registration file, or allow the default name to remain unchanged. The names of all registration files must include the *.lic exten-sion.

l Select the location of the license registration file. This file stores your license regis-tration information.

3. When the Register Software page reappears, perform one of the actions in the follow-ing table, depending on whether your computer has Internet access:

Internet access

Action

Yes Click the hyperlink to connect to the Waters License Activation Center web site.

No Move the software registration file that you just created to a computer with Internet access and then access http://www.wa-ters.com/activate/licenseintro.htm. Follow the instructions to activate your licenses. After you receive the activation file, move the file to the computer on which UNIFI software is installed.

4. When you obtain a license activation file, return to the licensing home page, and click Activate Licenses.

5. On the Activate Licenses page, select the license activation file you downloaded from the Waters License Activation Center Web site, and then click Next.

6. On the Activate Licenses - License Activation Complete page, click Finish.

Tip: If you are activating the base license, log out and then log back on to UNIFI software to access the software's complete functionality.

View active licensesTo view all activated licenses available for deactivation, click Deactivate Licenses from the Licensing home page. The Deactivate License page displays a list of all activated licenses and options, as well as, unused qualification licenses.

To view Qualification licenses, access the Qualification center (Qualification and Main-tenance > Manage > Administration > Licenses).

Create a new administrator account n Administration > Security > Users > Create > User Editor

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Create a new administrator account

After you activate licenses, Waters recommends that you create a new administrator account, and disable the administrator account shipped with the software. In the event that your administrator account becomes locked, Waters provides a utility to unlock the default administrator account.

See also: UNIFI System Administrator's Guide for information on the unlocking the default administrator account.

To create a new administrator account and assign it a license:

1. Log on to UNIFI Portal and then click Administration.

2. From the Security area, click Users.

3. From the Global User List page, click Create.

4. In the Account Settings tab of the User Editor, enter the information for the admin-istrator account.

User settings:

Option Description

User Name

Type a combination of your last name and first name. User account names must be unique. Because administrator is the default user name, you must type a user name other than "administrator", preferably a combination of your last and first name.

First Name

Type your first name.

Last Name

Type your last name.

Assigned roles

Click System Administrator.

Default role

Click Administrator.

Tip: There is no need to enter a password for this account. The first time you log on to UNIFI software with this account, the password defaults to your username and you must change the password.

5. Click Save.

6. Click Administration, and then click Assign Licenses from the Licensing section.

7. On the Assign License page, assign to the new administrator account a license.

Tip: When you assign a license, you do not need to confirm the action by clicking Save.

After you create a new administrator account and assign it a license, you must revoke the license from the default administrator account, and then disable the user account.

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To revoke the administrator account license and then disable it:

1. Click Administration > Licensing > Assign Licenses.

2. On the Assign Licenses page, click "Administrator, UNIFI", and then right-click Revoke.

Result: The number of available licenses increases by 1. 3. Click Administration > Security > Users.

4. From the Global User list, click administrator (UNIFI, administrator) user account, and then click Modify.

5. In the Account Settings tab of the User Editor, select Disabled from the Current Status field.

6. Click Save.

See also:

l Activate UNIFI licenses

Install a Microsoft loopback network adapterYou must install a Microsoft loopback network adapter if you install UNIFI software on a computer that is not included in a network. By installing the network adapter and using the computer’s IP address, you simulate a networked computer.

To install a Microsoft loopback adapter, do as follows:

l Add the loopback adapter hardware to your computer.

l Set up a network connection for the adapter.

To add the Microsoft loopback adapter hardware:

1. Click Start, enter "hdwwiz" in the Search box, and press Enter.

2. On the "Welcome to the Add Hardware Wizard - Welcome" page, click Next.

3. On the "Wizard can help you install other hardware" page, select "Install the hardware that I manually select from a list (Advanced)", and then click Next.

4. On the "From the list of hardware types" page, select Network adapters, and then click Next.

5. On the "Select Network Adapter" page, make the following selections, and then click Next:

l Manufacturer: Select Microsoft.

l Network Adapter: Select Microsoft Loopback Adapter.

6. On the "Wizard is ready to install your hardware" page, click Next.

7. On the "Completing the Add Hardware wizard" page, click Finish.

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Install a Microsoft loopback network adapter

To set up a connection to the Microsoft loopback adapter hardware:

1. From Control Panel, select Network and Sharing Center, and then click Change adapter settings.

2. Select the connection that was just created, which is usually named "Local Area Con-nection 2", and select Properties.

3. Select Internet Protocol (TCP/IPv4), and then click Properties.

4. In the Properties dialog box, verify that the options "Obtain an IP address auto-matically" and the "Obtain DNS server address automatically" are selected, click OK, and then close the dialog box.

5. Add a line to the DRIVE_LETTER:\WINDOWS\system32\drivers\etc\hosts file with the following format, after the localhost line:

IP_address hostname.domainname hostname

where

l 127.0.0.1 is the non-routable IP address

l hostname is the name of the computer

l domainname is the name of the domain

6. Open a command prompt, and ping the computer using only the host name specified in the host file.

Remove UNIFI software from a workstationPerform these operations when you want to remove UNIFI software from a workstation. If you want to update the software to a newer version, refer to the UNIFI Upgrade and Config-uration Guide.

Number Task Refer to this Help topic

1 Export all data folders.Rule: You must export data folders before you remove UNIFI soft-ware. If you do not export your data, the data will be irretrievably lost.

Export data from UNIFI

2 Take all instrument systems offline. Modify device status

3 Physically disconnect instrument systems from the workstation to prevent re-detection.

4 Remove all instruments and then all instrument drivers. Delete devices

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Number Task Refer to this Help topic

5 Decommission and then delete all instrument systems.Requirement: If you have qualification results and maintenance logs for an instrument system, you must export the results and then delete them from the Qualification Center before you can delete the instrument system.

Delete devices

6 Deactivate all licenses. If you have installed and used Qualification licenses, contact Waters Technical Support to deactivate used Qual-ification licenses.

Activate and deac-tivate licenses

7 Close Portal.

8 Uninstall the previous version of UNIFI software in either of the following ways: l Run the UNIFI installer again for the workstation. l Open the Microsoft Windows Control Panel, and use the Pro-

grams and Features option to uninstall a program.

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Remove UNIFI software from aworkstation

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4 Installing a UNIFI Workgroup

Contents:

Before you begin installing a workgroup server 41Install UNIFI software on a workgroup server 45Log on to the UNIFI portal 50Activate UNIFI licenses 51Create a new administrator account 53Install UNIFI software on a client 55Install UNIFI software on a laboratory network device 58Automate database backups to a network location 63Remove UNIFI software from a workgroup configuration 68

Before you begin installing a workgroup serverBefore you begin installing UNIFI software on a workgroup server, you must complete these tasks:

l Choose a database backup option.

l Configure disk drives.

l Create Windows application server role.

Choose a database backup optionWhen you install UNIFI software on a workgroup server, you must choose one of three backup options:

l Daily online (hot) backups

Tip: If you choose online hot backups as your database backup option, you can recover database in the event of database failure, no data are lost.

l Daily offline (cold) backups

l No backups

If you choose daily offline or online backups, the database backup runs automatically as a Windows scheduled task. You can modify the time in Windows Task Scheduler.

Online hot backups

If you select this option, these actions occur:

l A weekly full database backup plus daily incremental backups with archive log mode.

l Windows scheduled tasks named "At1" and "At2" are automatically created to back up the database.

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l "At1" scheduled task performs a full online database backup every Monday morn-ing at 2:59 a.m. (you can modify this time). It runs immediately after installing the database for first time.

l "At2" scheduled task performs an incremental backup Tuesday through Sunday at 2:59 a.m. (you can modify this time).

l During database backups, the database is online and available for use (users can log on to the software and they can acquire data).

When you select online hot backups as your database backup option, you can recover data-base in the event of database failure, no data are lost.

Offline cold backups

If you select this option, these actions occur:

l A full database backup occurs daily without archive log mode.

l A Windows scheduled task named "At1" is automatically created to back up the data-base every day at 2:59 a.m. (you can modify this time).

l During database backups, the database is offline and unavailable (users cannot log on to the software and they cannot acquire data).

l The amount of time it takes to back up the database depends on the size of the data (the larger the volume of data, the longer it takes to back up the database).

When you select offline cold backups as your database backup option, you can recover the database up to the point of the last backup; data captured between backups is lost.

Fast Recovery Area size

If you chose online, hot backups during installation, the location for your database backups (FRA) must be able to accept data from two backups simultaneously: the software does not delete the obsolete backup until it confirms that the current one is completed. Online, hot backups also include archive logs.

A database backup causes the software to generate a time-stamped log file that includes details about individual steps of the backup process. You can find this log file in this location: [install drive]:\Waters\scripts\BackupRecoveryScripts\logs.

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Retention of database backups

UNIFI Backup and Recovery options:

Option Description Recovery options

Daily online (hot) backups

A full online backup runs every Monday morning at 2:59 a.m. Incre-mental backups run Tuesday through Sunday at 2:59 a.m.

You can fully recover the database. In the event of database failure, no data are lost because the data are backed up in archive logs between backups.

Daily offline (cold) backup

A full offline backup runs every morning at 2:59 a.m. The database is not available during the backup process.

You can recover the database to the point of the last backup. In the event of database failure, data captured since the last backup are lost.

No backup

The software does not install a backup option.

You are responsible for backing up and restoring the database.

One full backup is kept in the Fast Recovery Area (FRA). Archive logs are removed when a new backup is made. When a new full database backup (level-0) is made, previous backups older than one week are removed from the FRA.

To recover the entire database, you must generate a second backup of the workgroup server, and then archive the contents of the Fast Recovery Area (FRA) to a network share or storage array.

The database is backed up and restored by using scripts that are installed on the workgroup server during installation. Only users with administrator and ora_dba privileges can backup and restore the database.

When the database is backed up, it typically compresses approximately 50 % compared to its original size.

Every time a database backup occurs, UNIFI software generates a log file that contains detailed information about the database backup process. The location of this log is: [install drive] waters\oracle\scripts\BackupRecoveryScripts\logs.

Configure disk drivesBefore you install UNIFI software on a workgroup server, you must configure one or three disk drives for Oracle Automatic Storage Management (ASM). If you are using external stor-age, you can configure one disk, but it must be at least a 500 GB drive. The disk groups that you create become the default location for the files created in the database. The disk group type determines how Oracle ASM mirrors files. An ASM disk can be a disk device.

To configure disk drives for Oracle ASM:

1. From the Windows Start menu on the workgroup server, right-click Computer, and then select Manage.

2. From the Computer Management dialog box, click Storage > Disk Management.

Important: Ensure all disks are online and unallocated.

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Before you begin installing a workgroup server

Tip: If a disk is online and has a drive letter assigned to it, right-click on the disk, select Delete Disk, and then Delete Volume. Right-click on the disk and select Delete Partition.

Disk Management:

Create Windows application server roleBefore you install UNIFI software on a workgroup server, you must create a Windows applic-ation server role that automatically configures .NET Framework 3.5.1 Features and Microsoft Message Queue (MSMQ) Server.

To create a Windows application server role:

1. On the workgroup server, open Server Manager from Administrative Tools.

2. Right-click Roles, and then select Add Roles.

3. In the Add Roles wizard, click Next.

4. In the Select Server Roles page, select Application Server, and then click Next.

5. In the Add Roles wizard, click "Add Required Features".

6. In the Select Server Roles page, click Next.

7. In the Application Server page, click Next.

8. In the Select Role Services page, select these services:

l TCP Port Sharing

l Message Queuing Activation

Tip: When Windows prompts you to confirm your request for additional features or services, click "Add Required Features", and click Next.

9. In the Select Role Services page, select these services:

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l HTTP Activation

l TCP Activation

l Windows Process Activation Service Support


10. In the Select Role Services page, select these services, and then click Next:

l Named Pipes Activation

l Web Server (IIS) Support


11. In the Web server (IIS) page, click Next.

12. In the Select Role Services page, click Next.

13. In the Confirm Installation Selections page, confirm these selections, and then click Install.

Confirm Installation Selections:

Application Server

.NET Framework 3.5.1

Web Server (IIS) Support

TCP Port Sharing

Windows Process Activation Service Support

HTTP Activation

Message Queuing Activation

TCP Activation

Web Server (IIS)

Web Server

14. In the Installation Results page, click Close.

15. On the Server Manager page, click Close.

Install UNIFI software on a workgroup serverWaters recommends a domain-based network infrastructure, though a UNIFI workgroup configuration does not require it. If the workgroup server is in a different domain than the clients or laboratory network devices, you must ensure that the date and time-stamps are synchronized with a time server. In a Windows Server 2008 R2-based domain, the domain controllers are automatically configured as time servers for the domain.

Restriction: Do not install UNIFI software on the same machine as the domain controller.To maximize uptime and minimize issues related to the network environment, Waters recom-mends that you follow these guidelines:

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Install UNIFI software on a workgroup server

l Organize all UNIFI–related accounts, computer and user, within the same domain.

l If you are using real-time virus scanning, exclude all UNIFI–related folders and their subdirectories. Some real-time virus scanners mistake normal UNIFI software func-tionality for virus activity, causing data buffering problems.

l Configure preferences in Oracle Enterprise Manager to notify you by email when disk space reaches a user-defined size. Doing so, helps you monitor database space usage. For more information, see the "Manage the server disk space" section in the UNIFI System Administrator's Guide.

Important: After you install UNIFI software, do not change the IP address of the workgroup server. It is important that the workgroup server maintains a static IP address.Changing either of these may render UNIFI software unusable.

Before you beginBefore you install UNIFI software on a workgroup server, configure these Windows settings:

l Verify Windows hosts file information

l Enable the correct option is enabled for Windows updates (not the "Install updates automatically" option).

l Configure network discovery and file and printer functions

l Configure the network LAN

l Confirm regional settings

l Identify location for database backup copies (if applicable)

Verify Windows hosts file informationBefore you install UNIFI software on the workgroup server, you must verify that the Windows hosts file information contains the correct IP address and server host name for the workgroup server.

To verify that the Windows hosts information is correct:

1. On the workgroup server, open the Windows hosts file (C:\Win-dows\System32\drivers\etc\hosts).

2. Verify that the file contains the correct IP address and the fully qualified domain name of the server.

Tip: The fully qualified domain name of the server is required for OEM to install properly.

Enable the correct option for Windows updatesYou must select the option "Check for updates, but let me choose whether to download them" for Windows updates.

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Configure network discovery and file and printer settingsOn the workgroup server, you must enable the network discovery and the file and printer sharing functions so that clients can communicate with the server. To enable the network discovery on a server in a domain, you must start certain services.

To start the required services on the workgroup server:

1. From Control panel, select Administrative Tools > Services.

2. Change the startup type to Automatic and start these services:

l DNS Client

l Function Discovery Resource Publication

l SSDP Discovery

l UPnP Device Host

When all services are running, you can modify the network discovery settings on the server.

To turn on the network discovery and file and printer sharing functions:

1. From the Start menu, open Control Panel > Network and Internet > Network and Sharing Center.

2. Click "Change advanced sharing settings", and turn on these functions:

l Network discovery

l File and printer sharing

Configure the network LANYou must configure the power management settings for the server to turn off the power saving feature and clear the Internet Protocol version 6 options.

To configure the network LAN settings:


2. Right-click on Local Area Connection, select Rename, and type Instrument LAN.

3. Right-click on the instrument LAN, and then click Properties.

Tip: If you are prompted for an administrator password or confirmation, type the pass-word or provide the confirmation.

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Confirm regional settingsIf you are installing UNIFI software on an English workstation, you must confirm that your Windows regional settings are configured for English (United States). The symbols for English (United States) use decimal, not comma formatting, which is important when display-ing numeric values ("12.56", not "12,56").

To confirm that you have the correct regional settings:

1. From the Windows "Search programs and files" text box, type Regional Settings.

2. In the Region and Language dialog box, ensure "English (United States)" is selected as the format in the Formats tab.

Identify location for database backup copiesIf you want to maintain a copy of your database backup external to the Oracle FRA location, you must identify a network storage device with sufficient space. Each time the database is backed up, a copy of the database backup is placed in this location. As a result, the storage space in this location diminishes quickly, and you must monitor the location to ensure that there is sufficient space to store the database backup copies.

Requirement: You must be able to access this location from the workgroup server because you browse to the location when you install the software.

Install UNIFI software on a workgroup serverThe Waters UNIFI installation wizard guides you through the installation process. Allow approximately 40 minutes to complete the installation.

Requirement: You must have unrestricted local Windows administrator or equivalent priv-ileges to install UNIFI v1.7 software.

When you install UNIFI software on a workgroup server, the language installed is based on the workgroup server's operating system language. If the workgroup server's operating system is English, the software is installed in English. You cannot install the Japanese version of UNIFI software, on an English application server.

See also: Before you install the workgroup server, refer to the UNIFI System Admin-istrator's Guide to determine your database backup option and your company's redundancy options for Oracle ASM.

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To install the UNIFI software on a workgroup server:

1. Insert the UNIFI DVD into the computer's DVD drive.

Tip: If the installer does not automatically start, open Window's Explorer, browse to the DVD drive, and double-click Setup.exe.

2. From the installation menu, click "Install UNIFI Workgroup Server".

3. On the "What do you want to install?" page, click "Install the UNIFI Application Server".

4. On the License Agreement page, read the agreement, click "I accept the terms of the license agreement", and then click Next.

5. On the Select an installation drive page, select the location UNIFI application soft-ware, and the Oracle database files.

6. On the Import Database page, select No if you are not importing the database or Yes to import the database, and then click Yes.

7. On the Oracle ASM drive selection page, select all the disks that you previously configured to use for Oracle ASM, select an ASM Redundancy, and then click Next.

Tip: You can select one disk if you are using external redundancy, but it must be at least a 500 GB drive.

If you previously selected one disk, the redundancy is automatically set to External.

Redundancy options:

Redundancy Description

High 3-way mirroring.

Normal 2-way mirroring (for most files by default), two copies of every data extent.

External No mirroring by ASM and relies on the storage system to provide RAID functionality.

8. On the Database Backup Options page, select a database backup option, and then click Next.

l Daily backups without archive log mode. (A full offline backup runs every morning at 2:59 a.m. In the event of a database failure, data captured since the last backup are lost.)

l Weekly backups with a daily incremental with archive log mode. (A full offline backup runs every Monday morning at 2:59 a.m., and incremental backups run every morning. In the event of a database failure, no data are lost.)

l No database backup. (Not recommended.)

9. On the ASM Recovery Settings page, select a backup recovery option:

l "Skip backup recovery area". The database backup files are stored in the Oracle ASM DATA disk group.

l "Enable backup recovery area". The database backup files are stored in Oracle FRA (Flash Recovery Area) disk group. If you select only one disk, the

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redundancy is external.

Tips:

l You can select a maximum of 20 hard drives.

l You cannot select the system drive, installation drive, ASM drives, or format-ted data drives.

10. On the Fast Recovery Area (FRA) Offline Storage Settings page, select whether you want to enable FRA offline storage to store copies of the database backups to offline storage. If you choose "Enable FRA Offline Storage", specify the location in which to store the copy of the database backups.

Tip: If you choose "Enable FRA Offline Storage" and want to copy the database backups to a network location, you must perform this procedure "Automate database backups to a network location" after you install the software on the workgroup server.

11. On the UNIFI Application Server settings page, accept the defaults, and then click Next.

12. On the Configure UNIFI policy and audit trail settings page, perform one of these oper-ations:

l To comply with GxP guidelines and regulations, click "Configure settings for a reg-ulated environment (GxP)".

l To configure settings for a non-regulated environment, click "Configure settings for a non-regulated environment".

See also: Appendix A for system policy and audit trail settings for a regulated and non-regulated environment.

13. On the Ready to Install page, click Install.

14. On the Installation Wizard Completed page, a message indicates whether the install-ation was successful, and you can click the link to open the Waters Installation Summary. If the software was not successfully installed, submit a request for Waters technical support at this Web address: http://www.waters.com/irequest. To complete the installation, click Finish.

Tip: If you close the installation wizard, and you want to open the installation log, browse to C:\Windows\WatersInstallationSummary.

See also: For instructions on how to qualify the software, see the Workgroup Qualification Protocol which is available on the UNIFI Qualification media. For more information about qualification, refer to the "Qualification Overview" document on this media.

Log on to the UNIFI portalAfter you install UNIFI, you must log on to the UNIFI portal to register the software and activ-ate your licenses.

Tip: When you restart the workgroup server, wait at least five minutes before logging on to UNIFI software, to allow time for Waters Service Host to restart.

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To log on to UNIFI:

1. On your desktop, double-click UNIFI Portal .

2. In the Login dialog box, type "administrator" in both the User name and Password fields.

3. On the Welcome page, click Administration, and then click Licensing, where you can register and activate product licenses.

Activate UNIFI licensesUse the Waters Licensing Management System to activate or deactivate the purchased soft-ware's product licenses and options. Waters' licenses apply to a UNIFI system and user accounts. You can assign and revoke UNIFI named-user licenses to user accounts as needed.

Workgroup license and options:

License type

Required Definition

System base

Yes Configures the database as a UNIFI workgroup. The base license includes no named-user licenses.

UNIFI named-user

Yes You can activate a maximum of 10 named-user licenses to increase the number of users. Named-user licenses are required for users to log on to the software.

Instrument control

Yes One instrument control license is required for each online instru-ment system.

Large molecule named-user

No If your instrument system includes a time of flight (TOF) mass spec-trometer, this named-user license is required to perform Peptide Map and Intact Protein analysis and must be assigned to user accounts.

Small molecule named-user

No If you want to process the data using the Dealkylation, MassFrag-ment and IsoScore tools, this named-user license is required and must be assigned to user accounts.

Waters scientific library

No If you want to import a Waters scientific library, the appropriate library license is required. Tip: You can import and export your own scientific library.

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Activate UNIFI licenses

Qualification licenses:

License type

Required for qual-ification

Definition

Qualification- software

Yes If you want to qualify the workgroup configuration, you must purchase a license for each device: workgroup server, labor-atory network device, and client.

Qualification- instrument

Yes To qualify instruments on a workgroup, you must activate these licenses: l The UNIFI Instrument Qualification Module license is

required for each LC instrument included in an instru-ment system.

l The UNIFI Instrument Qualification Standard Tech-nology MS license is required for each Xevo TQ , Xevo TQD, Xevo TQ-S mass spectrometer.

l The UNIFI Instrument Qualification High Technology MS license is required for Xevo G2 TOF, Xevo G2 -S TOF, Xevo G2-S Q TOF mass spectrometers.

l The UNIFI Instrument Qualification Accessory license is required for each instrument accessory module.

After you install UNIFI software, you must register, activate, and assign to users UNIFI named-user licenses by using the licensing wizard in UNIFI software and the Internet as follows:

l Create a software registration file using the licensing wizard.

l Submit the software registration file to the Waters License Activation Center Web site, and receive a license activation file.

l Activate your licenses and options using the licensing wizard and the license activation file.

Register and activate licensesYou must register and activate the UNIFI base license to access UNIFI software. You can activate licenses other than the base license at the same time or after activating the base license, but not before doing so.

Pre-requisite: To complete the licensing process, you must have purchased UNIFI licenses from Waters and obtained a serial number for each purchased license.

To register licenses:

1. On the Licensing Home page, click Register Software.

2. On the Request Software page, perform these operations, and then click Next:

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l Type a new name for the software registration file, or allow the default name to remain unchanged. The names of all registration files must include the *.lic exten-sion.

l Select the location of the license registration file. This file stores your license regis-tration information.

3. When the Register Software page reappears, perform one of the actions in the follow-ing table, depending on whether your computer has Internet access.

Internet access

Action

Yes Click the hyperlink to connect to the Waters License Activation Center web site.

No Move the software registration file that you just created to a computer with Internet access and then access http://www.wa-ters.com/activate/licenseintro.htm. Follow the instructions to activate your licenses. After you receive the activation file, move the file to the computer on which UNIFI software is installed.

4. When you obtain a license activation file, return to the licensing home page, and click Activate Licenses.

5. On the Activate Licenses page, select the license activation file you downloaded from the Waters License Activation Center Web site, and then click Next.

6. On the Activate Licenses - License Activation Complete page, click Finish.

Tips: l If you are activating the base license, log out and then log back on to UNIFI soft-

ware to access the software's complete functionality.

l When you create an instrument system and bring it online, an instrument system license is automatically assigned it. You cannot bring instrument systems online if there are no instrument system licenses available.

View active licensesTo view all activated licenses and available for deactivation, click Deactivate Licenses from the Licensing home page. The Deactivate License page displays a list of all activated licenses and options, as well as, unused qualification licenses.

To view Qualification licenses, access the Qualification center (Qualification and Main-tenance > Manage > Administration > Licenses).

Create a new administrator account n Administration > Security > Users > Create > User Editor

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Create a new administrator account

After you activate licenses, Waters recommends that you create a new administrator account, and disable the administrator account shipped with the software. In the event that your administrator account becomes locked, Waters provides a utility to unlock the default administrator account.

See also: UNIFI System Administrator's Guide for information on the unlocking the default administrator account.

To create a new administrator account and assign it a license:

1. Log on to UNIFI Portal and then click Administration.

2. From the Security area, click Users.

3. From the Global User List page, click Create.

4. In the Account Settings tab of the User Editor, enter the information for the admin-istrator account.

User settings:

Option Description

User Name

Type a combination of your last name and first name. User account names must be unique. Because administrator is the default user name, you must type a user name other than "administrator", preferably a combination of your last and first name.

First Name

Type your first name.

Last Name

Type your last name.

Assigned roles

Click System Administrator.

Default role

Click Administrator.

Tip: There is no need to enter a password for this account. The first time you log on to UNIFI software with this account, the password defaults to your username and you must change the password.

5. Click Save.

6. Click Administration, and then click Assign Licenses from the Licensing section.

7. On the Assign License page, assign to the new administrator account a license.

Tip: When you assign a license, you do not need to confirm the action by clicking Save.

After you create a new administrator account and assign it a license, you must revoke the license from the default administrator account, and then disable the user account.

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To revoke the administrator account license and then disable it:

1. Click Administration > Licensing > Assign Licenses.

2. On the Assign Licenses page, click "Administrator, UNIFI", and then right-click Revoke.

Result: The number of available licenses increases by 1. 3. Click Administration > Security > Users.

4. From the Global User list, click administrator (UNIFI, administrator) user account, and then click Modify.

5. In the Account Settings tab of the User Editor, select Disabled from the Current Status field.

6. Click Save.

See also:

l Activate UNIFI licenses

Install UNIFI software on a clientThe Waters UNIFI installation wizard guides you through the installation process. Allow approximately 15 minutes to complete the installation.

Recommendations:

l If you are using DHCP, reserve the IP address for the client.

l After you install UNIFI software on a client, do not change the IP address or computer name of the client.

When you install UNIFI software on a client, the language installed is based on the client's operating system language. If the client's operating system is English, the software is installed in English. You cannot install the Japanese version of UNIFI software, on an English client.

Before you beginBefore you install UNIFI software on a client, configure these Windows settings:

l Turn on Microsoft Message Queue (MSMQ) server

l Configure the power options

l Turn on the network discovery and file and printer settings

l Ensure the correct option is enabled for Windows updates (not the "Install updates automatically" option).

l Verify connectivity between client and workgroup server

Turn on MSMQ ServerBefore you install UNIFI software on a client, you must turn on MSMQ Server.

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Install UNIFI software on a client

To turn on MSMQ:


2. Click the option to "Turn Windows features on or off".





Configure the power optionsYou must configure the power management settings for the client to turn off the power saving feature.

To configure the power options:

1. From Windows Control Panel, click System and Security, and then Power Options.

Alternate: From the Search Programs and Files, type Power Options. 2. On the Power Options page, click Show additional plans, select High performance,

and then click "Change plan settings".

3. On the Edit Plan Settings page, perform these tasks, and then click Save changes:

l Select Never from the "Turn off the display" field.

l Select Never from the "Put the computer to sleep" field.

4. On the Edit Plan Settings page, click "Change advanced power settings".

5. In the Power Options dialog box, complete these tasks, and then click OK.

Client power option settings:

Power options Setting

Expand Hard Disk and "Turn off hard disk after"

Type Never in the Setting(Minutes) field

Expand Sleep settings:

Sleep after Never

Allow hybrid sleep Off

Hibernate after Never

Allow wake timers Disable

Expand USB settings and "USB selective suspend"

Disabled

Expand Display and "Turn display after" Never

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Turn on network discovery and file and printer sharing settingsEnable the Windows network discovery and file and printer sharing settings on the client.

To turn on Windows network discovery and file and printer sharing settings:

1. From Windows Control Panel, click "Network and Internet".

2. From the Network and Internet page, click "Network and Sharing Center".

3. From the Network and Sharing Center page, click "Change advanced sharing set-tings".

4. From the Change sharing options for different network profiles, expand one of the pro-files, and then make these selections:

l From Network discovery, click "Turn on network discovery".

l From File and printer sharing, click "Turn on File and printer sharing".

5. Click Save changes.

Enable the correct option for Windows updatesYou must select the "Check for updates, but let me choose whether to download them" option for Windows updates. Ensure that the "Automatic updates" option is disabled.






Verify connectivity between the client and workgroup serverBefore you install UNIFI software on a client, ensure it can connect to the workgroup server by pinging the server.

To ping the workgroup server:

1. From Windows' Explorer "Search programs and files", type Run, and press Enter.

2. In the Run dialog box, type cmd.exe.

3. In the Command prompt window, type ping <IP Address>, where IP Address is the IP address of the server.

Install UNIFI software on a clientYou can install UNIFI software on client from the product DVD.

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Install UNIFI software on a client

Install UNIFI software from the product DVD

Requirement: You must have Windows administrator privileges to install UNIFI v1.7 soft-ware.

To install the UNIFI software on a client computer:



2. From the installation menu, click Install UNIFI Workgroup server.

3. On the "What do you want to install?" page, click "Install the UNIFI client".

4. On the License Agreement page, read the agreement, click "I accept the terms of the license agreement", and then click Next.

5. On the Select an installation drive page, perform one of the following tasks:

l Click Next to install the software on the C drive.

l Select a drive other than C to install the software on a different drive.

6. On the UNIFI Application Server Settings page, type the name or IP address of the workgroup server, and then click Next.

7. On the Ready to install page, click Install.

8. On the Installation Wizard Complete page, click Finish.

Tip: If the verification failed, click the link to open the installation log file. If the software was not successfully installed, submit a request for Waters technical support at this web address: http://www.waters.com/irequest. If you close the installation wizard and you want to open the installation log, browse to C:\Windows\WatersInstallationSummary.

After you install UNIFI software on a client

After you install UNIFI software on a client, you can install a UNIFY print driver; however, you must install UNIFI software first and then the UNIFY print driver. For instructions on how to install the UNIFY print driver, see the NuGenesis 8 Installation and Configuration Guide.

Install UNIFI software on a laboratory network deviceLaboratory Network Devices (LNDs) control and collect data acquired from connected instru-ment systems. You can purchase one from Waters Corporation, or you can configure a custom LND. Waters recommends that you purchase an LND that is pre-configured to work with UNIFI software.

When you install UNIFI software on an LND, the language installed is based on the LND's operating system language. If the LND's operating system is English, the software is installed in English. You cannot install the Japanese version of UNIFI software, on an English LND.

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Recommendations:

l After you install UNIFI software on an LND, Waters recommends that you do not change the IP address or computer name of the LND.

l If you are using DHCP, Waters recommends that you reserve the IP address for the LND.


Before you beginIf you install UNIFI software on a Waters laboratory network device, ensure the correct option is enabled for Windows updates (not the "Install updates automatically" option).

Install UNIFI software on a custom laboratory network deviceIf you install UNIFI LND software on a computer other than the Waters UNIFI Laboratory Network Device, you must perform these tasks:

l Ensure the correct option is enabled for Windows updates (not the "Install updates automatically" option).


l Turn on the network discovery function and file and printer sharing function.

l Turn on MSMQ server.

l Configure the power options.

l Configure the instrument LAN.

l Configure the Windows firewall settings.

Enable the correct option for Windows updatesYou must select the option "Check for updates, but let me choose whether to download them" for Windows updates.






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Install UNIFI software on a laboratory network device

Turn on network discovery and file and printer sharing settingsEnable the Windows network discovery and file and printer sharing settings on the labor-atory network device.

To turn on Windows network discovery and file and printer sharing settings:

1. From Windows Control Panel, click "Network and Internet".

2. From the Network and Internet page, click "Network and Sharing Center".

3. From the Network and Sharing Center page, click "Change advanced sharing set-tings".

4. From the Change sharing options for different network profiles, expand one of the pro-files, and then make these selections:

l From Network discovery, click "Turn on network discovery".

l From File and printer sharing, click "Turn on File and printer sharing".

5. Click Save changes.

Turn on the Microsoft Message Queue ServerBefore you install UNIFI software on a computer other than the Waters UNIFI Laboratory Network Device, you must turn on the MSMQ server.

To turn on the server:


2. Click the option "Turn Windows features on or off".





Configure the power optionsYou must configure the power management settings for the LND to turn off the power saving feature.

To configure the power options:

1. From Windows Control Panel, click System and Security and then Power Options.

Alternate: From the Search Programs and Files, type Power Options. 2. On the Power Options page, click Show additional plans, select High performance,

and then click "Change plan settings".

3. On the Edit Plan Settings page, perform these tasks, and then click Save changes:

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l Select Never from the "Turn off the display" field.

l Select Never from the "Put the computer to sleep" field.

4. On the Edit Plan Settings page, click "Change advanced power settings".

5. In the Power Options dialog box, do the following tasks, and then click OK.

LND power option settings:

Power options Setting

Expand Hard Disk and "Turn off hard disk after"

Type Never in the Setting(Minutes) field

Expand Sleep settings:

Sleep after Never

Allow hybrid sleep Off

Hibernate after Never

Allow wake timers Disable

Expand USB settings and "USB selective suspend"

Disabled

Expand Display and "Turn display after" Never

Configure the Instrument LAN You must configure the power management settings and assign the IP address for the Instru-ment LAN to communicate with the instruments. Log on to the LND as the local admin-istrator.

l Configure the power management settings

l Configure IP address

To configure the power management settings:


2. Right-click Instrument LAN, and then click Properties. If you are instructed to enter an administrator password or confirmation, do so.



To configure the IP address:


2. Right-click Local Area Connection, Instrument LAN, and then click Properties.


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4. Select Internet Protocol Version 4 (TCP/IPv4), and then click Properties.

5. In the Internet Protocol Version 4 (TCP/IPv4) Properties dialog box, click "Use the fol-lowing IP address".

6. Assign the following IP address and Subnet mask, and then click OK:

l IP address: 192.168.0.1

l Subnet mask: 255.255.255.0

Result: The assigned setting is saved for the local area connection, instrument LAN.

Configure the Windows firewall settingsFor a laboratory network device, you must configure Windows firewall settings to turn off the Windows firewall for the Instrument LAN (public network).

Tip: For the instruments to communicate with the LND, you must configure the LND's Windows firewall settings.

To configure the Windows firewall settings:

1. Click Start > Control Panel > Network and Internet > Network and Sharing Center > Windows Firewall.

Alternative: Right-click Network from the desktop and then select Properties > Windows Firewall.

2. On the Windows Firewall page, click "Turn Windows Firewall on or off".

3. On the Customize Settings page, perform these tasks, and then click OK:

l Click "Turn on Windows Firewall" for the "Home or work (private) location set-tings".

l Click "Turn off Windows Firewall (not recommended)" for the "Public network loc-ation settings".

Install UNIFI software on a laboratory network deviceThe Waters UNIFI installation wizard guides you through the installation process. You should allow approximately 30 minutes to complete the installation.

Requirement: You must have administrator privileges to install UNIFI v1.7 software.

To install the UNIFI software on a laboratory network device:



2. From the installation menu, click "Install UNIFI Workgroup server".

3. On the "What do you want to install?" page, click "Install the UNIFI laboratory network device".

4. On the License Agreement page, read the agreement, click "I accept the terms of the

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license agreement", and then click Next.

5. On the Select an installation drive page, perform one of these operations:

l Click Next to install the software on the C drive.

l Select a drive other than C to install the software on a different drive.

6. On the UNIFI Application Server settings page, type the name or IP address of the workgroup server, and then click Next.

7. On the UNIFI Database Settings page, click Next.

8. On the Ready to install page, click Install.

9. On the Installation Wizard Completed page, click Finish.

Tip: If the verification fails, click the link to open the installation log. If the software was not successfully installed, submit a request for Waters technical support at this web address: http://www.waters.com/irequest. If you close the installation wizard and you want to open the installation log, browse to C:\Windows\WatersInstallationSummary.

Automate database backups to a network locationIf you chose "Enable FRA Offline Storage" during software installation and want to automate the copying of database backups to a network location, you must modify the OracleSer-viceUNIFI and the OracleASM Listener services to include a named user account. The named user account can be local user account or domain user account. The domain user account is always referred as <domain name\user account>.

Tip: This procedure documents how to automate the copying of the database backups to a network location. It does not include data moved to an offline location by an offline storage management system.

To copy database backups to a network location using a named user account, you must perform these tasks:

l Create an OS or domain user account with the correct permissions

l Create a network share for stored database backups and provide access to the OS or domain user account

l Add credentials to access the network share to automatically access the network

l Create the OracleCRSToken Service and then manually set the password

l Stop the database and Oracle listener

l Stop Oracles services, if necessary, and then specify that services can run with a local or domain user account

l Grant permission to the named user to use the Oracle resources

l Start services

l Start the database and then restart the server

l Verify backups are copied to network location by running the At1 or At2 database backup scheduled tasks

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Create an OS user account with the correct permissionsThe user can be a domain user or a local user. If the user is on a different domain than the server, a trust relationship must exist between the two domains. If you want to use a domain user account, you may want to create a new one, because this account's password will never expire and cannot be changed. You must exempt this domain user account from any policies that require password changes.

Requirement: The user must be part of the ORA_DBA and the local Administrators group.

Create local user accounts

To create an OS user on the local server with the correct permissions:

1. On the server, open Server Manager.

2. In the Server Manager window, expand Configuration > Local Users and Groups.

3. Click Action, and then New User.

4. In the New Action User dialog box, perform these tasks, and then click OK:

l Type the Full name and description of the user.

l Select these password settings: "User cannot change password" and "Password never expires".

5. Right-click the user you just created, and then select Properties.

6. In the Properties dialog box, select the Member Of tab, click Add to add the "Admin-istrators" and "ora_dba" groups to this user account.

Create domain user accounts

If you are using a domain account, you must add the domain account to the local "Admin-istrators" and "ora_dba" group.

To add domain account to required groups:

1. On the local server, open Server Manager.

2. In the Server Manager window, expand Configuration > Local Users and Groups > Groups.

3. Right-click on Administrators group > Properties.

4. In the Administrator’s properties dialog box, click Add.

5. in the Select Users, computers, service accounts, or groups dialog box, type <domain\username> in the "Enter the objects name to select" text box.

6. Click OK.

7. When prompted enter a user account and password for an account that contains the privilege to add to the group.

Create a network share to store database backupsTo store database backups on a network share, you must perform these tasks:

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l Identify the directory to store the database backups.

l Create a network share.

l Grant permissions to the local or domain user account to this network share.

To identify a database backup directory and create a network share:

1. Locate a directory to store the database backups.

2. Right-click Properties on the directory you are going to share.

3. On the Properties dialog box, click the Sharing tab, and then click Advanced Sharing.

4. In the Advanced Sharing dialog box, perform these tasks:

l Click “Share this folder”.

l Enter the share name (typically OfflineBackup$, but you can change the share name to anything you want).

l Click Permissions.

5. On the Share Permissions tab, click Add, type the domain or local user account in the "Enter the object names to select" text box, and then click OK.

6. On the Share Permissions tab, select your OS or domain user account, and then click Full Control.

7. Click Apply, and then click OK.

8. On the Advanced Sharing tab, click OK.

To grant permissions to the local or domain user account to this network share:

1. On the Properties dialog box, click the Security tab, and then Advanced.

2. On the Advanced Security settings page, click Change Permissions, and then click Add.

3. In the Select, User, computer, Service Account, or Group dialog box, type the domain or local user account in the "Enter the object name to select" text box and then click OK.

4. In the Permission Entry dialog box, click Allow Full Control, and then click OK.

5. In the Permissions tab of the Advanced Security Settings dialog box, click OK.

6. In the Security tab, click close.

Add credentials to automatically access the network shareYou can add the credentials of the domain or local user account to automatically access the network share.

To add the credentials to automatically access the network share:

1. From Control Panel > User Accounts > Credential Manager, click Add a Windows Cre-dential.

2. In the Add a Windows Credential page, perform these tasks, and then click OK:

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l Type the computer name of where the network share resides in the "Internet or network address" text box.

l Type the <domain name\ user account> in the User Name text box.

l Type the password for this account.

Result: The name of the network computer appears in the list under Windows Credentials.

Create the OracleCRSToken Service and then manually set the pass-word

This service, also known as OSTS, simplifies access control and identity propagation across heterogeneous platforms.

See: Oracle Security Token Service 11gR2 document from Oracle.

To create the OracleCRSToken Service:

1. From the server, open a command prompt, and then type this command:

l Set Oracle_home= C:\Waters\oracle\asm

l Type crsuser add <domainname>\<username>

Tip: For a local user, specify the nodename\username 2. When prompted for the password, press [Enter] to leave the password blank.

Example:C:\waters\oracle\asm\cruser add devtest\orauser

Enter the password for oracle domain\oracluster: [Press Enter].

To manually set the password for the OracleCRSToken Service:


2. Open services, right-click the OracleCRSToken service, and then select Properties.

3. In the OracleCRSTokenService dialog box, perform on these tasks:

l On the Log On tab, locate the OS user account you just created, and then type and confirm this user's password.

l On the General tab, set the Startup Type to Automatic, and then start the service.

Stop the database and Oracle listenerYou must stop the database and then Oracle listener.

To stop the database and Oracle listener:

1. From the server, open a command prompt.

2. From the Command window, change the directory to C:\Waters\Oracle\ASM and then type these commands:

l C:\Waters\oracle\ASM>srvctl stop database -d <database name>

l C:\Waters\oracle\ASM>srvctl stop listener

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Tip: The default <database name> is UNIFI.

Stop servicesConfirm that the OracleServiceUNIFI and OracleASMTNSListener services are stopped. If for some reason these service are not stopped, you must stop them by using the Windows Manage Services feature.

You must also set the services to run with the domain or local user account.

To specify that the Oracle services can run with the domain or local user account:

1. For the OracleServiceUNIFI service and OracleASMTNSListener service right-click Properties.

2. In the Properties dialog box, select the Log On tab, and then select the option to log on as "This account" and type the local or domain user account and password in the "This account" box.

Important: Do not browse to select the user account, you must type the domain\user account or local user account and password in the "This account" text box.

Grant permissions to the named userYou must grant permissions to the local or domain user account that you previously created to use Oracle resources.

From the server, open a command prompt, change the directory to C:\Water-s\oracle\ASM\BIN, and then type these commands:

l C:\Waters\oracle\ASM\BIN>crsctl setperm resource ora.LISTENER.lsnr-o <domain name>\user account

l C:\Waters\oracle\ASM\BIN>crsctl setperm resource ora.unifi.db -o<domain name>\user account

Start servicesYou must start these services on the server: OracleASMTNSListenener and OracleSer-viceUNIFI.

To start the services:


2. Open services, right-click the OracleServiceUNIFI and OracleASMTNSListener ser-vices, and select Start.

Modify the database backup tasks to run as the local or domain user account

You must modify the database backups tasks (At1 and At2) to run as the local or domain user account.

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To modify the database tasks:

1. In Task Scheduler, open the Task Scheduler library.

2. Right-click At1 and select Properties.

3. In the General tab of the At1 Properties dialog box, select "Windows Vista, Windows Server2008" in the Configure for text, and then click "Change User or Group".

4. In the Select User or Group dialog box, type the <domain name\user account> in the "Enter the object name to select" text box, and then click OK.

5. In the Windows Security dialog box, type the user name and password of the domain or local account that has permissions to change the scheduled tasks on the local server, and then click OK.

6. When prompted type the password for the local or domain user account and then click OK.

7. Repeat all previous steps for At2 scheduled task.

Start the database and then restart the serverYou must restart the database first to ensure that all the services are back online and then restart the server to refresh the environment.

To restart the database, open a command prompt from the server, and type the following: C:\Waters\oracle\ASM\>srvctl start database -d <database name>.

Restart the server.

Verify backups are copied to network location You can verify that the database backups will be copied to the network location by manually running the At1 or At2 scheduled task.

To manually run the database backup tasks:

1. In Task Scheduler, open the Task Scheduler library.

2. Right-click At1 or At2 and select Run.

Once completed, verify that the network share contains the database backup. To verify that the task is completed, click Actions > Display All Running Tasks in the Task Scheduler window.

Tip: If you didn't enable FRA Offline Storage during installation, you must edit the scheduled tasks for both hot and cold backups as outlined in the "Archive database backups" section of the UNIFI System Administrator's guide.

Remove UNIFI software from a workgroup configurationWhen you must remove UNIFI software from a workgroup configuration, perform these oper-ations in sequence:

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Number

Task Refer to this Help topic

1 Export all data folders.Rule: You must export data folders before you remove UNIFI software. If you do not export your data, the data will be irretrievably lost.

Export data from UNIFI

2 Take all instrument systems offline. Modify device status

3 Physically disconnect instrument systems from labor-atory network devices, to prevent re-detection.

4 Decommission and then delete all instrument systems.Requirement: If you have qualification results for an instrument system, you must export the results and then delete them from the Qualification Center before you can delete the instrument system.

Delete devices

5 Remove all instruments and then all instrument drivers. Delete devices

6 Change the status of all laboratory network devices from online to offline, and then to decommissioned. Important: Once decommissioned, do not restart labor-atory network devices because they will re-register on the workgroup server.

Modify device status

7 Change the status of clients from online to decom-missioned. Important: Once decommissioned, do not restart the clients because they will re-register on the workgroup server.

Modify device status

8 Deactivate all licenses from the workgroup server. If you installed and used Qualification licenses, contact Waters Technical Support to deactivate used Qualification licenses.

Activate and deac-tivate licenses

9 Close Portal.

10 Uninstall UNIFI software in either of these ways: l Run the UNIFI installation wizard again for each of

these devices: client, laboratory network device, and workgroup server.

l Open the Microsoft Windows Control Panel, and user the Programs and Features option to uninstall a program.

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5 Managing the Database

Contents:

Back up the workstation database 71Restore the workstation database 73

Back up the workstation databaseYou can back up and restore the UNIFI workstation database using the following Backup and Restore scripts located in this folder:

<installation_directory>:\Waters\Oracle\Scripts\BackupRecoverScripts.

Workstation Scripts Purpose

Backup.bat Performs a cold full backup of the database.

Rmanwarchlv0.cmd Performs a hot full backup of the database.

Rmanwarch.cmd Performs a hot incremental backup of the database.

Important: Make a copy of the BackupRecoverScripts folder, and put the copy in a secure location, retaining the original folder in the event you modify the backup scripts.

Before you back up the workstation databaseBefore you back up the UNIFI workstation database, complete these tasks:

l Confirm that the instrument system is idle.

l Ensure all Portal sessions are closed.

Windows user groups When you install UNIFI software on a workstation, two user groups are automatically created: UNIFI operators and ora_dba. Do not modify or delete these user groups.

The UNIFI operators group includes services that are required for UNIFI software to function properly.

The ora_dba group is created by Oracle and automatically includes the user name of the administrator who installs UNIFI software. Users who belong to this group can log on to the database locally and perform SYSDBA functions.

Requirement: You must be a member of the ORA_DBA group on this workstation to perform a database backup.

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Back up database to default locationYou can back up the database to the default location <installation drive>:\Waters \oracle\-fast_recovery_area or to a specified location.

To back up the UNIFI database:

1. From the Windows Start menu, type cmd in the Search programs and files.

2. Right-click cmd.exe, and then select Run as Administrator.

3. From within the command window, at the command prompt, type the following command to change directories:

cd C:\

<installation_drive>:\Waters\oracle\scripts\BackupRecoveryScripts

4. At the command prompt, type the following command "backup".

Result: The backup script runs in verbose mode, so that you can view its progress.Important: When the backup process finishes, the command prompt appears, ready to receive another command.

To view the backup log file:

1. Open Windows Explorer, and navigate to this file system location:

<installation_drive>:\Waters > Oracle > Scripts > BackupRecoverScripts > logs

Tip: The backup script creates the log file using the following naming convention:MonthDayYearHourMin.log: for example, May0220111105.log.

2. To view the log file content, open it in Notepad or another text editor.

Back up database to a specified locationYou can back up the database to a specified location by editing the rmanbackup file.

To edit the rmanbackup file:

1. Open Windows Explorer, and navigate to this file system location:

<InstallationDirectory>:\Waters > Oracle > Scripts > BackupRecoverScripts.

2. Select rmandbackup and the right-click Edit.

3. In Notepad, after db_recovery_file_dest_size command, type this new command: SQL 'alter system set db_recovery_file_dest="<location>" scope=both';

Where location is the backup location (for example: D:\Backup).

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4. Click Save and then close Notepad.

5. Run the Backup.bat file.

Result: A database backup is created in the location you specified.

Managing backup-related filesThe Waters UNIFI workstation backup process keeps only the last two backups in the AUTORECOVERY and BACKUPSET folders. When you complete a third backup, the latest version (by date) backup is deleted.

The backup process creates and stores backup-related files in the following folders in the installation directory:

<installation_directory>WATERS > ORACLE > FLASH_RECOVERY_AREA > UNIFI folder

l AUTOBACKUP folder includes a sub-folder named Year_Month_Day: for example, 2011_05_02. This folder contains a *.BKP file, which contains a backup of your control files.

l BACKUPSET folder includes a sub-folder named Year_Month_Day. This folder con-tains a *.BKP file, which contains a backup of your database data files and table spaces.

Recommendation: Periodically back up the WatServiceHost logs and the portal folders contained in the C:\ProgramData\Waters\Logs folder.

To back up the WatServiceHost logs and portal folders:

1. From within a Windows Explorer window, show hidden folders.

2. Navigate to the C:\ProgramData folder, to view its content.

3. In the ProgramData folder > Waters > Logs folder, copy the oldest WatServiceHost logs and portal files into another folder to save as backup.

4. In the ProgramData > Waters > Logs folder, delete the oldest files, and keep only the newest files.

Requirement: Do not delete these files: l Waters.Deployment.InstallUtil.exe.log

l Waters.UdfTypeScannerlog

l DetectInstrument.log

Restore the workstation databaseYou can back up and restore the UNIFI workstation database using the following Backup and Restore scripts located in this folder:

<installation_directory>:\Waters\Oracle\Scripts\BackupRecoverScripts.

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Restore the workstation database

Workstation Scripts

Purpose

Backup.bat Cold backup of the database and calls RManBackup.cmd which performs a full backup.

Rmanwarchlv0.cmd Performs a hot full backup of the database.

Rmanwarch.cmd Performs a hot incremental backup of the database.

EXECLOG Called in the RestoreDB.bat script.

When you restore the workstation database, it is recovered to the last backup only. No recov-ery occurs from REDO logs because the restore scripts contain a "noredo" option.

Tip: It is important that the computer name and IP address remain the same for the data-base restoration process to work correctly. If you are replacing the workstation with a new computer, you cannot restore the database on a new workstation with a different computer name and IP address.

Before you restore the workstation databaseBefore you restore the UNIFI workstation database, you must complete these tasks:

l Confirm that the instrument system is in an idle state.

l Close the UNIFI portal.

l Verify your Oracle sys account password and your Oracle SID because they are required to run the scripts. The default Oracle SID is UNIFI.

l Verify your database ID. You can find the database ID in the backup.log.files.

To restore the UNIFI workstation database:

1. From the Windows Start menu, type cmd in the Search programs and files.

2. Right-click cmd.exe, and then select Run as Administrator.

3. In a command window, at the command prompt, type the following command line to change directories:

cd <installation_directory>:\Waters\oracle\scripts\BackupRecoveryScripts

4. At the command prompt, type the following command, followed by your Oracle SID and your Oracle sys password:

restoredb.bat <Oracle SID> <your_Oracle_sys_password><database ID>

Example: C:\ RestoreDB.bat UNIFI Oracle 4282913195See also: UNIFI System Administrator's Guide, "Record database information" for instruc-tions on how to find the database ID. The database ID may be recorded on the Change information page in UNIFI software. To access this page, log on to Portal and then click Administration. From the Administration page, click Software Management and then UNIFI information.

Rule: The Restore script does not run in verbose mode. Depending on the size of your data-base, the restoration process can require several minutes.

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Important: The restoration process replaces all data files, control files, and table spaces from the most recent backup. It does not restore changes made after your last backup. Any changes made since the last backup will be lost. When the restoration process ends, the command prompt appears, ready to receive another command.

To view the restore log:

1. Open Windows Explorer, and navigate to the this folder:

<InstallationDirectory>Waters > Oracle > Scripts > BackupRecoverScripts folder.

2. To view the content of the restore.log file, open it in Notepad or another text editor.

Tip: Each time you restore the database, the restoration process appends additional inform-ation to the restore.log file.

Restore database from a specified locationIf you backed up the database from a specified location, rather than the default location (C:\Waters \oracle\fast_recovery_area), you must modify the DBRestoreWKSN.sql file to change the database recovery file destination location.

To modify the DBRestoreWKSN sql file:

1. Open the DBRestoreWKSN sql file in Notepad.

2. Update the db_recovery_file_dest = '<new specified location>' in two places in this file.

Where <new specified location> is the database backup location (for example: D:\Backup).

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6 Verifying the installation

Contents:

Verify installed files on a workstation 77Verify installed files for a workgroup 78

Verify installed files on a workstationAfter you install the UNIFI software and licenses, you can generate a Verify Files report.

To generate the Verify Files report:

1. Click Administration > Qualification and Maintenance.

2. On the Qualification and Maintenance page, select Qualify > Qualify Software.

3. Select the workstation, and then click "Execute Verify Files for selected line" .

4. In the Configuration pane, select the History tab, and then click "Verify files report" or the "Extended Verify files report" link to open the report.

Tip: You can view and print two versions of the Verify files report: the Verify files report and the Extended Verify files report. The Verify files report lists the checksums at the folder level and the Extended Verify files report lists all files for all folders that are checked and verified during installation. The difference between these two reports is approximately 50 pages.

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Verify files report example:

Verify installed files for a workgroupAfter you install the UNIFI software and licenses, you can generate a Verify Files report for each device that comprises a workgroup configuration.

Tip: The Verify Files report can require several minutes to generate.

To generate the Verify Files report:

1. Click Administration > Qualification and Maintenance.

2. On the Qualification and Maintenance page, select Qualify > Qualify Software.

3. On the Qualify Software page, select Clients, Laboratory Network Devices, or Work-group Servers, and then click the "Execute Verify Files for selected line" icon.

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Tip: To select multiple LNDs and clients, press [Shift] and left-click .

Qualify Software:

4. In the Configuration pane, select History tab, and then click the "Verify files report" or "Extended Verify files report" link to open the report.

Tip: You can view and print two versions of the Verify files report: the Verify files report and the Extended Verify files report. The Verify files report lists the checksums at the folder level and the Extended Verify files report lists all files for all folders that are checked and verified during installation. The difference between these two reports is approximately 50 pages.

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Verify installed files for a workgroup

The Verify Files report displays in the Report Viewer page. You can print this report.

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7 Troubleshooting

Contents:

Record a problem 81UNIFI Installation troubleshooting 81

Record a problem n Start > Search programs and files > Problem Steps Recorder

To record your interactions with a software application when it encounters a problem, use the Microsoft Windows 7 utility called Problem Steps Recorder. The utility records the prob-lem by creating step-by-step screen captures enhanced with descriptive text. It then saves the screen captures and text to a zip file, which you can email to experts for troubleshooting.

To record a problem:

1. Click Start, and in the "Search programs and files" text box, type Problem Steps Recorder.

2. Click Start Record, and perform the actions that produce the problem.

Tips: l To pause the recorder, select Pause Record.

l To add a comment to the record, select the area of the window that you want to comment on, and then click Add Comment.

3. Click Stop Record.

4. In the Save As dialog box, type a name for the zip file, and then specify its location.

UNIFI Installation troubleshootingThis chapter provides solutions to problems you can encounter while installing the UNIFI soft-ware. It describes possible symptoms and corrective actions.

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Problem Symptom Solution

Cannot log on to UNIFI soft-ware using the administrator account from a workstation or a workgroup server.Tip: You cannot check Waters Service Host from a client computer.

The error message: “Cannot find Service…” appears.

Verify that the Waters Service Host is started: 1. Right-click My Computer. 2. Click Services and Applications > Services. 3. In the Services area, select Waters Service

Host, and verify the status is Started, and the Startup Type is set to Automatic (delayed start). If the service is not started, click Start or Restart the service.

Cannot import files from other applications into UNIFI soft-ware.

The Waters UNIFI Printer does not appear in the Windows printer list.

If you did not install the Waters UNIFI printer when you installed UNIFI software, you cannot import files from other applications into UNIFI software. If you want to import files from other applications into UNIFI software, you must install the components required to import these two file types: l Reports: Waters UNIFI printer l Data files: Waters internal printer queue

Cannot log on to UNIFI portal using a client computer.

This error message appears: "This UNIFI client is not registered or it was decommissioned. Please use a valid one or contact your system administrator".

Restart Waters Client services: 1. From the Start menu, right-click My Com-

puter > Manage. 2. In the Computer Management dialog box,

click Services, and Applications > Services. 3. In the Services area, double-click WatCli-

entServiceHost and then click Start.


The error message appears: "Portal session closed because the application server was offline or unavailable".

Contact your system administrator.Determine if network is down. If the network is down, a UNIFI client cannot communicate with the workgroup server.If the workgroup server is not down, wait ten minutes and try again to log on to UNIFI.

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7 Troubleshooting



The error message appears: "Downloading this file from server <IP address> error occurred."

Complete one of these operations: l Uninstall and then reinstall UNIFI software

on the client, and specify the server's host name, not the IP Address needed to connect to the workgroup server.

l Modify LAN settings as follows: l In Internet Explorer, click Tools > Internet

Options. l On the Internet Options dialog box, click

Connections, and then click LAN set-tings.

l On the Local Area Network (LAN) Set-tings dialog box, clear the check box "Use a proxy server for your LAN".

Cannot perform data-base backup on a work-station.

You must be a member of the ORA_DBA group on this workstation to back up the database.

Cannot qualify software.

Server IQ stops at the 50 % mark and fails to create report.

If you are installing UNIFI software on an English workstation or workgroup server, you must confirm that your Windows regional settings are configured for English (United States). The symbols for English (United States) use decimal, not comma formatting, which is important when displaying numeric values ("12.56", not "12,56").To confirm that you have the correct regional settings: 1. From the Windows "Search programs and

files" text box, type Regional Settings. 2. In the Region and Language dialog box,

ensure "English (United States)" is selected as the format in the Formats tab.

Cannot bring LND online after migrating or upgrading the workgroup server.

You must upgrade UNIFI software on a labor-atory network device after you upgrade or migrate the workgroup server.

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UNIFI Installation troubleshooting


Database backup did not run auto-matically.

If your workgroup server is located outside the US, you may need to create a database backup schedule tasks in Windows Task Scheduler. Refer to the UNIFI System Administrator's Guide for the procedure to create a database schedule task.

Cannot view Waters printer.

Windows collapses all devices from the same manufacturer in a single icon. The Waters Internal Print Queue sometimes only appears in Windows Devices and Printers.

In Windows Devices and Printers, right click Waters UNIFI printer to display all Waters' print-ers.

Cannot select the ASM data disk drives during soft-ware install-ation.

ASM data disk drives are not enabled on the Oracle ASM drive selec-tion page of the installer.

The ASM data disk drives are allocated. They must be online and unallocated.Tip: If a disk is online and has a drive letter assigned to it, right-click on the disk, select Delete Disk, and then Delete Volume. Right-click on the disk and select Delete Partition.

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Cannot down-load UNIFI license activ-ation file from the Waters web site.

Windows Internet Explorer version 9 restricts an encrypted file from being down-loaded.

Turn off the "Do not save encrypted pages to disk" option in the Internet Options dialog box.To turn off this feature, do the following: 1. In IE 9, click Tools (Alt-X) > Internet options. 2. In the Internet Options dialog box, click the

Advanced tab. 3. On the Advanced tab, clear the "Do not save

encrypted pages to disk" option in the Secur-ity section, and then click OK.

Cannot down-load UNIFI license activ-ation file from Waters web site.

Windows Internet Explorer version 10 restricts an encrypted file from being down-loaded.

Turn off the "Do not save encrypted pages to disk" option in the Internet Options dialog box.To turn off this feature, do the following: 1. In IE 10, click Tools (Alt-X) > Internet

options. 2. In the Internet Options dialog box, click the

Advanced tab. 3. On the Advanced tab, clear the "Do not save

encrypted pages to disk" option in the Secur-ity section, and then click OK.

4. On the Security tab, select Internet, click Cus-tom level, and then click OK.

5. Scroll down to the Downloads option and then click Enable, and then click OK.

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7 Troubleshooting

A GMP Default Installations

Contents:

Default settings overview 87Data folders 89Global policies 90Folder policies 94Roles 96Predefined reasons 100Predefined meanings and comments 108Custom fields 109User account 109Event properties 110

Default settings overviewWhen you install UNIFI software, you decide whether you want to configure policy and audit trail settings for a regulated (GxP) or non-regulated environment. If you chose "Configure settings for a regulated environment (GxP)", UNIFI software configures data folders, global policies, folder policies, roles, custom fields, event properties, an administrator user account, and predefined reasons to comply with GxP (Good Practice quality guidelines and regu-lations). You can change these settings at any time.

If you chose "Configure settings for a regulated environment (GxP)", UNIFI software config-ures these policies and settings.

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Default settings for a non-regulated environment:

Policy Description

Global policies

Global policies establish rules for the entire system, such as how to display the time and date in the software.

Folder policies

UNIFI software applies the GMP data folder reason policy to the Company (root) data folder. This folder policy defines whether users are required to enter a reason and their passwords when they modify or delete objects such as, analysis injections, processing of analyses, reports, that reside in data folders. If you don't want to apply this policy to all folders, you can revoke it.

Predefined reasons

Reasons explain why users performed an action, such as, modified an analysis method, deleted a data folder, or approved a report. Reasons created in advance save users time because once they are created, users can select an appropriate reason from a list and do not need to create their own reason. Previously created reasons are called "predefined" and ensure that reasons recorded within the event log are consistent.

Roles Roles are a set of permissions that control users' ability to perform tasks and functions in the software. Roles are based on users' job functions, such as a chemist or lab technician. Initially, the UNIFI software ships with the system administrator, chemist, analyst, guest, and field service engineer roles, but you can define as many roles to suit your company's needs.

User accounts

UNIFI software is shipped with one default Administrator account.

Custom fields

Custom fields track, manage, calculate, and report information about results, samples, extracted report information, and scientific applications. Initially, the UNIFI software ships with custom fields used by qualification, but you can define as many custom fields to suit your company's needs.

Event prop-erties

The event log stores audit trail messages in the event browser, system audit trail, and data audit trail view. Each message resides within a category; for example, Acquisition, Data Management, and Security and Administration, and contains a severity level and export requirement.

Predefined meanings and comments

When users review items, such as reports, for approval or rejection, they must provide a "meaning". Comments explain why users approve or reject an item, such as a report or qualification results. Previously created meanings and comments are called "predefined".

If you chose "Configure settings for a non-regulated environment (non GxP)", UNIFI soft-ware configures these global policies.

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Default global policy settings for non-regulated environment:

Policy Settings Description

Audit Trail Reasons

No reasons and passwords required.

Users do not need to supply a reason and their password when they modify or delete a system object.

Timeout 60 minutes for both inactive work sessions and Signoff dialog box.

The number of minutes that a work session can remain inactive before the application closes and users must enter their user names and passwords to log back on to the software.The number of minutes that the Signoff dialog box can remain inactive before it closes.

User Account

No password or limit to the number of failed authen-tication attempts.

No user account password requirements and no limit to the number of times that users can enter their user name and password incorrectly before their account status is changed from active to disabled.

Qualification No qualification requirements

No tasks are required prior to performing a qualification.

The data folder policy "Non GxP" is applied to the Company data folder and users do not need to supply a reason and their password when modify or delete objects such as analysis injections and reports that reside in data folders.

Data folders n Administration > Security > Access Management > Data Folders

When you install UNIFI software, the software installs these default data folders:

The Company\Templates\Waters English folder contains the default templates and methods shipped with the software. After you install the software, you can import default projects, in the form of .uep files, from the product DVD.

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Data folders

Global policies n Administration > Security > Global Policies

Global policies establish rules for the entire system, such as how to display the time and date in the software. You can change these default settings anytime.

Audit Trail Reasons global policyAudit Trail Reasons global policy define whether users must supply a reason and their pass-word when they modify or delete a system object, such as a data folders, role, or data folder policy.

Audit Trail Reasons policy default settings:

Global policy

Reason Password required

Consumables Modify or delete solvents, columns, or sample trays.

Modify User-defined No

Delete User-defined Yes

Data folder Modify or delete data folders.


Delete Predefined Yes

Device folder Modify or delete a device folder, or change the status of a device from offline to decommissioned. In a workstation, this category only pertains to an instrument system when its status changes from offline to decommissioned.



Event Log Delete or export and remove event log records.


Fields Modify or delete custom fields and formulas.



Folder policy Modify or delete data folder policies.



Global policy Modify global policies.

Modify User-defined Yes

LIMS Modify or delete a LIMS configuration.

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Global policy

Reason Password required



Offline stor-age manage-ment

Modify or delete an offline storage configuration



Qualification Maintenance log entry

Modify or delete a qualification maintenance log entry.



Qualification method

Modify or delete a qualification method.



Qualification Result

Delete a qualification result.


Roles Modify or delete user roles.



Scientific library

Modify or delete compounds and structures in the scientific library.



UNIFI Soft-ware

Change database password, and manage error log reporting

Modify Predefined Yes

User Modify or delete user accounts.



Date and time global policyThe date and time global policy defines the display of the date and time format in the soft-ware.

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Global policies

Date and time global policy:

Global policy

Description Option selected

Include day of week

The day of the week is abbreviated to three characters, such as "Tue" for Tuesday and "Wed" for Wednesday and included with the date and time.

No

Display with 24-hour time

The time is recorded in 24-hour intervals, not 12-hour intervals. Example: 22:26:19 instead of 10:26:19.

Yes

Include time zone name

The full, time-zone name is included with the date and time, not the abbreviated version of the time zone.Example: Greenwich Mean Time, not GMT.

Yes

Show the time zone offset

The time-zone offset (the hour difference from the standard 24 time zones of the world) is included with the date and time.

No

Audit Trail global policyThe Audit Trail global policy defines the number of users (one or two) who must approve exporting and removal of records from the event log.

Audit Trail global policy:

Global policy Description Option selected

The number of users (one or two) who must give their approval to export and remove records from the event log.

When users export and remove event log records from the event browser, system audit trail, or imported events of the event log, specify the number of users who must approve this action by entering their user names and passwords in the Export and Remove Authorization dialog box: l To require only one user to approve the removal of

records, click "One user must authorize removal." l To require two users to approve the removal of

event log records, click "Two users must authorize removal."

One user must authorize removal

Timeout global policyThe Timeout global policy defines the number of minutes that sessions and the Signoff dialog box can remain inactive before closing, forcing users to enter their user names and pass-words to reopen a session or continue the approval process.

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Timeout global policy:

Global Policy

Description Minutes

Session Timeout (GXP)

The number of minutes that a work session can remain inactive before the application closes and users must enter their user names and pass-words to log back on to the software. Other users can log on to UNIFI, but only an individual user can unlock a session.

15

Print Session Timeout

The number of minutes that a print session can remain inactive before users must log on the UNIFI printer again. This feature is not selected by default.

6

Signoff Inactivity Timeout (ES)

The number of minutes that the Signoff dialog box can remain inactive before it closes.

8

User Account global policyThe User Account global policy defines the password requirements and number of times users can try to authenticate themselves (by entering their user names and passwords) before the software locks their account.

User Account global policy:

Global policy Description Settings

Enforce unique user passwords (GxP)

The number of times users must enter a unique password before a former password can be reused.

16

Set password expiration time-frame (GxP)

The number of days until user passwords expire. (Users are prompted to change their passwords.)

90

Set minimum password length (GxP)

The minimum number of characters contained in users' passwords. You cannot modify this option.

8

Limit number of authentication attempts (GxP)

The maximum number of times that users can enter their user name and password incorrectly before their account status is changed from active to disabled.

4

Qualification global policyYou can specify the tasks required prior to performing a qualification run and whether users can electronically sign qualification reports.

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Global policies

Qualification global policy:

Global policy Description Option selected

Approved qual-ification methods

You can specify that approved qualification methods are required before performing a qualification run.

Yes

Specify approvals required prior to qualification run

You can specify that approved installation qualification (IQ) tests are required prior to performing Operational or Performance Qualification (OQ/PQ) tests.

Yes

Add performer train-ing certificates

You can specify that field service personnel must have a training certificate associated with their user accounts before they can perform a qualification run.

Yes

Sign qualification reports using elec-tronic signatures

You can specify that users can electronically sign qual-ification reports using electronic signatures.

Yes

Folder policies n Administration > Security > Access Management > Policies > Global folder policy list

When you define folder policies, you establish rules for the content items in the data folders. The data reason policy defines whether users are required to enter a reason and their pass-words when they modify or delete objects that reside in data folders. The GMP folder policy is applied to the Company folder and all folders beneath it inherit this policy.

When you install UNIFI software, you decide whether you want to configure policy and audit trail settings for a regulated (GxP) or non-regulated environment. If you chose "Configure settings for a regulated environment (GxP)", UNIFI software applies the GMP data folder reason policy to the Company (root) data folder. This folder policy defines whether users are required to enter a reason and their passwords when they modify or delete objects such as, analysis injections, processing of analyses, reports, that reside in data folders. If you don't want to apply this policy to all folders, you can revoke it.

Policy name: GMPDescription: Waters provided settings - Review against your SOPs before using.

GMP folder reason policy:

Data Policy Action

Users must supply a reason Password required

Analysis injec-tions

When they modify or delete injections from an analysis.



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Data Policy Action


Analysis method When they modify or delete an analysis method.



Change Channel Offset time

When they modify the time-offset value for each detector plumbed in series to automatically align the retention time of components eluting from each detector.


File data When they delete file data stored in a data folder.


Manual calib-ration

Modify the calibration curve to ignore or not ignore points in an analysis.


Manual integ-ration

Modify the peak area of a chromatogram in an analysis. Delete a peak, baseline, or drop line of a chromatogram in an analysis.


Delete User-defined No

Manual peak assignment

Modify, replace, or remove the component's peak assign-ment in a chromatogram within an analysis.


Manual peptide assignment

Modify, replace, or remove the manual assignment of the peptide in a chromatogram within an analysis.


Manually identify component

Modify, identify, or remove a component in a chro-matogram within an analysis.


Printer method When they modify or delete a printer method.



Processing of analyses

When they process an analyses.

Modify No Reason No

Report extraction method

When they modify or delete a report extraction method.



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Folder policies

Data Policy Action


Report template and objects

When they modify or delete a report template or objects.



Reports When they delete a report.


Sample set and analyses

When they modify or delete a sample set or analyses.



Signature method When they modify or delete a signature method.



Startup/shutdown method

When they modify or delete a startup or shutdown method.



Roles n Administration > Roles > Roles Editor

Roles are a set of permissions that control users' ability to perform tasks and functions in the software. Roles are based on users' job functions, such as a chemist or lab technician. Initially, the UNIFI software ships with the system administrator, chemist, analyst, guest, and field service engineer roles, but you can define as many roles to suit your company's needs. Role name: AdministratorDescription: UNIFI System AdministratorPermissions: All permissions are assigned to this role.Recommendation: After you activate licenses, Waters recommends that you create a new administrator account and disable the administrator account that is shipped with the soft-ware. In the event that your administrator account becomes locked, Waters provides a utility to unlock the default administrator account.

Role name: AnalystDescription: Default settings for analyst

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Default Analyst role permissions:

Permission category Permissions assigned to this role

Acquisition Access General Instrument Settings

Analysis Center Access Review ModeCreate AnalysisCreate Analysis MethodModify Analysis InformationModify Analysis MethodModify Running Sample ListSave Analysis

Event Log View Event Log

Export/Import Export/Import data

Qualification and Maintenance View Maintenance RecordsView Qualification Records

Reporting Create Report Template/ObjectModify Report Template/Object

Role name: ChemistDescription: Default settings for chemist

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Roles

Default Chemist role permissions:


Acquisition Access General Instrument SettingsCreate Instrument SystemCreate Startup/Shutdown MethodManage Instruments DriversModify Instrument SystemModify Startup/Shutdown Method

Analysis Center Access Investigate ModeAccess Review ModeCreate AnalysisCreate Analysis MethodLock/Unlock Analysis MethodModify Analysis InformationModify Analysis MethodModify Running Sample ListSave Analysis

Custom Fields Create custom fieldLock/unlock custom fieldModify custom field

Devices Manage Laboratory Network DeviceModify Device

Event Log Export eventsImport and delete imported eventsView Event Logs

Explorer Modify additional information

Export/Import Export/Import dataRestore File Data

Qualification and Maintenance View Maintenance RecordsView Qualification Records

Reasons Create Predefined ReasonsModify Predefined Reasons

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Reporting Create Report Extraction MethodCreate Report Template/ObjectElectronically Sign ReportsLock/Unlock Report Extraction MethodModify Report Extraction MethodModify Report template/Object

Scientific Library Configure Scientific Library

Role name: Field Service EngineerDescription: Default settings for FSE

Default FSE role permissions:


Acquisition Access Advanced Instrument SettingsAccess General Instrument SettingsAccess Service Instrument SettingsCreate Instrument SystemCreate Startup/Shutdown MethodManage Instruments DriversModify Instrument SystemModify Startup/Shutdown Method

Analysis Center Access Investigate ModeAccess Review ModeAdd injection to analysisCreate AnalysisCreate Analysis MethodLock/Unlock Analysis MethodModify Analysis InformationModify Analysis MethodModify Running Sample ListRemove injection from analysisSave Analysis

Custom Fields Create custom fieldLock/unlock custom fieldModify custom field

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Roles


Devices Manage Laboratory Network DeviceModify DeviceView Decommissioned Devices

Export/Import Export/Import data

Qualification and Maintenance Add maintenance records linksApprove Maintenance RecordsCan sign as Performer of Qualification ResultsCreate Maintenance RecordsImport/Export Qualification MethodsImport/Export Qualification ResultsLock/Unlock Qualification MethodsModify Qualification MethodsQualify InstrumentsQualify SoftwareRemove maintenance records linksSchedule Instruments QualificationSchedule Software QualificationSchedule MaintenanceTake ownership Qualification runView Maintenance RecordsView Qualification Records

Reporting Create Signature MethodElectronically Sign ReportsModify Signature Method

Users Add Training Certificates

Role name: GuestDescription: Minimal access for temporary guestsPermissions: No permissions are assigned to this role.

See also:

l Create a new administrator account

Predefined reasons n Administration > Security > Predefined Reason Editor

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Reasons explain why users performed an action, such as, modified an analysis method, deleted a data folder, or approved a report. Reasons created in advance save users time because once they are created, users can select an appropriate reason from a list and do not need to create their own reason. Previously created reasons are called "predefined" and ensure that reasons recorded within the event log are consistent. These tables lists the predefined reasons that are shipped with the software.

Global policies categories:

Select this category:

To provide reasons why users perform this task:

Examples

Consumables Modify or delete a solvent, changed columns, or sample trays.

Modify: l Changed solvents l Changed columnsDelete: No longer in use.

Data Folder Modify or delete or data folders.

Modify: Folder status was changed from online to offline.Delete: Folder was archived.

Device folder Modify device folders or move instrument systems to another laboratory network device. Delete device folders. Tip: You can delete only those device folders created by users (facility/department and lab device folders). You can move device folders.

Modify: l Folder was moved to a

new location. l Folder was renamed. l Client status was

changed from online to decommissioned.

l Instrument system was moved to another LND.

Delete: l Folder was archived. l Client was removed. l Laboratory network

device was decom-missioned and removed from this loc-ation.

Event Log Delete or export and remove event log records. Tip: You cannot modify event log records.

Delete: Events were expor-ted removed per SOP <xxxx>.

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Predefined reasons



Examples

Fields Modify or delete custom fields.

Modify: Modified the formula of the custom field, or changed precision in custom field.Delete: l Custom field was obsol-

ete.

Folder Policy: Data

Modify or delete a data folder reason policy. Modify: Changed reason requirements.Delete: Policy is obsolete.

Folder Policy: Offline stor-age

Modify or delete an offline storage folder policy.

Modify: Changed offline storage requirements.Delete: Policy is obsolete.

Global Policy: Audit Trail

Modify the Audit Trail global policy. Tip: You cannot delete global policies.

Modify: Changed the number of users required to export and remove the audit trail records.

Global Policy: Audit Trail Reason

Modify the Audit Trail Reason global policy. Tip: You cannot delete global policies.

Modify: Changed the reason and password requirements for the <x> category.

Global Policy: Date and Time

Modify the Date and Time global policy. Tip: You cannot delete global policies.

Modify: l Removed the day of the

week from the date format.

l Included time zone off-set in the date format.

Global Policy: Qualification

Modify the Qualification global policy.Tip: You cannot delete global policies.

Modify: l Changed the type of sig-

nature from hand-written to electronic for a qualification report per SOP <xxx>.

Global Policy: SMTP

Modify the SMTP (email) global policy.Tip: You cannot delete global policies.

Modify: Changed the default email sender's address.

Global Policy: Timeout

Modify the Timeout global policy. Modify: Session timeout was changed per SOP <xxx>.

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Examples

Global Policy: User Account

Modify the User Account global policy. Tip: You cannot delete global policies.

Modify: Password require-ments were changed per SOP <xxx>.

LIMS Modify or delete a LIMS configuration.

Modify: Modified the sample lists that are imported from LIMS.Delete: LIMS configuration was obsolete.

Offline stor-age manage-ment

Modify or delete an offline storage config-uration.

Modify: Modified the offline storage system.Delete: Offline storage system was obsolete.

Qualification: Maintenance Log Entry

Modify or delete a maintenance log entry in the Qualification Center.

Modify: Entry <XXX> was incorrect and therefore changed to entry <YYY>.Delete: Entries were deleted because they were backed up and archived.

Qualification: method

Modify or delete a qualification method.

Modify: l Replaced signature

method l Approved Qualification

methodDelete: l The Qualification pro-

ject method was backed up and is no longer in use.

Qualification: Result

Delete a qualification result. Tip: You cannot modify a qualification result.

Delete: The result was backed up and is no longer in use.

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Predefined reasons



Examples

Roles Modify or delete user roles.

Modify: l Changed permissions

for Chemist role. l Changed role descrip-

tion. l Modified role by adding

or deleting permissions.Delete: l Deleted role because it

is no longer needed. l Deleted role based on

policy <xxx>.

Scientific Library

Modify or delete scientific library entities which are not a library nor library item (uses, classes, synonym, types, amino acid modifiers, digest reagents). Delete scientific libraries.

Modify: New structures were added to support products <xxx>.Delete: Library <xxx> is no longer in use.

UNIFI soft-ware

Modify the properties of a database Tips: l You cannot delete the database. l You can change the size of the database

for workstation configurations only.

Modify: Changed database password per SOP <xxx>.

User Modify or delete user accounts.

Modify: New role was added based on additional job responsibilities.Delete: User has left the company and the account status was changed to removed based on SOP <xxx>.

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Data folder categories:



Examples

Analysis injec-tions

Modify or delete injections from an analysis.

Modify: Injections were added to the analysisDelete: Injections were removed from the analysis

Analysis Method Modify or delete an analysis method.

Modify: Method was not accurate, parameter <x> changed.Delete: Method was backed up.

File Data Delete items in a data folder.

Delete: Items were expor-ted.

Manual Calib-ration

Modify the calibration curve to ignore or not ignore points in an analysis.

Modify: l Points ignored because

the injection was bad l Point included because

ignore issue has been addressed

l Point ignored because there was interference with the component detection

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Predefined reasons



Examples

Manual integ-ration

Modify the peak area of a chromatogram in analysis. Delete a peak, baseline, or drop line of a chromatogram in an analysis.

Modify: l Matrix interference. l Integration starts at

higher levels than baseline signal.

l Added peak because it was not integrated.

l Integration starts before peak starts.

l Integration stops before baseline signal level is reached.

l Two adjacent peaks are not integrated well.

l Excessive peak tailing. l Integration starts after

peak starts. l Analyte peak shows

tendency to split into two peaks.

Delete: l Deleted peak is below

the lower limit of quant-itation.

l Deleted drop line because analyte peaks shows a tendency to split into two peaks.

l Deleted peak is not at the correct retention time.

Manual peak assignment

Modify, replace, or remove the compon-ent's peak assignment in a chromatogram within an analysis.

Modify: l Peak manually

assigned l Peak assignment manu-

ally removed

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Examples

Manual peptide assignment

Modify, replace, or remove the manual assignment of the peptide in a chro-matogram within an analysis.

Modify: l Peptide manually

assigned l Peptide assignment

manually removed l Peptide assignment

manually edited

Manually identify component

Modify, identify, or remove a component in a chromatogram within an analysis.

Modify: l Component manually

replaced l Component manually

identified l Component iden-

tification removed

Printer Method Modify or delete a print method.


Processing of analyses

Reprocess analysis data. Modify: l Reprocessed analysis

data l Reprocessed analysis

data with manual integ-ration

l Reprocessed analysis data with discarded manual changes

Report Extraction Method

Modify method parameters or delete a report extraction method.


Reports Delete a report. Delete: Report was backed up.

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Predefined reasons



Examples

Report Template and Objects

Modify or delete report template para-meters and objects, and delete a report template and objects.

Modify: Template was not accurate, parameter <x> changed.Delete: Template was backed up.

Sample Sets and Analyses

Modify or delete a sample set or an analyses.

Modify: Reprocessed data with updated method.Delete: Sample set was backed up.

Signature Method Modify method parameters or delete a signature method.

Modify: Modify the signature method to add new signer.Delete: The signature method was backed up.

Startup/shutdown method

Modify method parameters or delete a startup/shutdown method.

Modify: l Modify the flow rate in

the startup method. l Changed temperature

in shutdown method.Delete: The startup and shutdown method was backed up.

Predefined meanings and comments n Administration > Signature method > Predefined Meanings and Predefined Comments

When users review items, such as reports, for approval or rejection, they must provide a "meaning" for the signature—what context they reviewed and signed the report. Comments explain why users approve or reject an item, such as a report or qualification results. Previ-ously created meanings and comments are called "predefined". These tables lists the predefined meanings and comments that are shipped with the software.

Predefined meanings:

Type of action: Meanings

Approve Responsibility

Approve Authorship

Approve Review

Approve Approve

Reject Reject

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Predefined comments:

Type of action: Comments

Approve Approve qualification results.

Approve Report approved because it met SOP <xxx>.

Approve Approve instrument IQ results.

Approve Approve software IQ results.

Approve Report approved for release.

Reject Software IQ failed.

Reject IQ failed. Software may need to be reinstalled.

Reject Instrument IQ failed.

Reject Report rejected because the data was incorrect.

Reject Instrument qualification failed.

Reject Report rejected because required information was missing.

Reject Instrument qualification failed. Perform OOS investigation.

Custom fields n Administration > Manage Custom Fields and Formulas

Custom fields track, manage, calculate, and report information about results, samples, extracted report information, and scientific applications. Initially, the UNIFI software ships with custom fields used by qualification, but you can define as many custom fields to suit your company's needs.

Default custom fields and formulas:

Custom Fields Description Data type

Amount pass Used by qualification Component

Qualification Amount Used by qualification Sample Component

Qualification RT Used by qualification Sample component

RT pass Used by qualification Component

RMS Error mDa Component

Root Mean Square PPM Component

User account n Administration > Security > Users

UNIFI software is shipped with one default Administrator account.

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Custom fields

Recommendation: After you activate licenses, create a new administrator account, and disable the administrator account that is shipped with the software. In the event that your administrator account becomes locked, Waters provides a utility to unlock the default admin-istrator account.

Default administrator account:

Account settings Value

User name administrator

First name UNIFI

Last name Administrator

Language English

Assigned roles System Administrator

Default role Administrator

Status and password settings

Current status Active

See also:

l Create a new administrator account

Event properties n Administration > Event Log > Event Properties

The event log stores audit trail messages in the event browser, system audit trail, and data audit trail view. Each message resides within a category; for example, Acquisition, Data Management, and Security and Administration, and contains a severity level and export requirement. The tables below list the severity level for each action.

You can change the severity levels if your role include the Manage event properties permis-sion.

The Acquisition table content depends on the instrument drivers installed on your UNIFI system.

Acquisition event properties:

Action Severity

A Spectrum was added to item Information

Acquisition Aborted Alert

Acquisition list execution complete Information

Acquisition list submitted Information

Acquisition modified Information

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Action Severity

Acquisition removed Alert

Acquisition submitted Information

Analytical Data Conversion Error Alert

Analytical Data Conversion Result Information

Buffer system created Information

Buffer system deleted Information

Buffer system modified Information

Calibration values have been set Warning

Calibration verification completed Warning

Calibration verification has error Warning

Characterize needle and loop volume failed Warning

Characterize needle seal readiness failed Warning

Characterize needle and loop volume failed Warning

Communications failure Alert

Copied Startup Shutdown method Information

Create Instrument System Information

Create Laboratory Network Device Information

Created Startup Shutdown method Information

Created amino acid modifier Information

Created classifier Information

Created column Information

Created digest reagent Information

Created item Information

Created item class Information

Created item use Information

Created library Information

Created modification. Information

Created solvent definition Information

Created synonym type Information

Created tag Information

Data Management Failure Alert

Data Management Success Information

Delete a capture item from the system Alert

Delete Laboratory Network Device Alert

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Event properties

Action Severity

Delete Library error Alert

Delete Library finished Information

Delete Library started Information

Delete Library stopped Information

Deleted amino acid modifier Information

Deleted classifier Information

Deleted column Information

Deleted digest reagent Information

Deleted Instrument System Alert

Deleted item Alert

Deleted item class Information

Deleted item use Information

Deleted library Information

Deleted modification Information

Deleted Startup Shutdown method Information

Deleted solvent definition Information

Deleted tag Information

Device reset Information

Erbium Calibration has been aborted Warning

Erbium Calibration has been started Warning

Export configuration of Scientific Library updated Information

Exporting items job Finished Information

Exporting items job Started Information

Exporting items job Stopped Information

Exporting items job error Alert

File Data Conversion Failed Warning Warning

File Data Import Error Alert

File Data Import Summary Information

File Data Import Warning Warning

Imported file Information

Importing items job error Alert

Importing items job finished Information

Importing items job started Information

Importing items job stopped Information

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Action Severity

Importing items job waiting Information

Injection aborted Alert

Instrument alignment offset changed Information

Instrument Deleted Alert

Instrument IP address conflict Warning

Instrument Model is added Information

Instrument Model is deleted Information

Instrument Model is updated Information

Instrument System Decommissioned Information

Instrument System Locked Information

Instrument System Moved Warning

Instrument System Offline Information

Instrument System Online Information

Instrument System Unlocked Information

Instrument already exists in another LND Warning

Instrument disabled Alert

Instrument drivers not synchronised with the AppServer Alert

Instrument enabled Information

Instrument firmware loading Information

Instrument skipped DHCP scan Information

Invalid structure format Alert

Item was moved to another library Information

IP address has Changed Information

Laboratory Network Device Decommissioned Information

Laboratory Network Device Machine Restarted Information

Laboratory Network Device Services Restarted Information

Laboratory Network Device Status Changed Information

Laboratory Network Device failed to update drivers Alert

Library export failed Alert

Library export success Warning

LND forced offline Information

LND initialization completed Information

LND initialization failed Alert

Locked Startup Shutdown method Information

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Event properties

Action Severity

Low disk space warning Warning

Mercury Calibration has been aborted Warning

Mercury Calibration has been started Warning

Modified amino acid modifier Information

Modified synonym type Information

Modified Column Information

Modified digest reagent Information

Modified instrument system Information

Modified item Information

Modified item class Information

Modified item use Information

Modified Laboratory Network Device Information

Modified library Information

Modified solvent definition Information

Modified solvent name Information

Modified Startup Shutdown method Information

Modified structure creation job configuration Information

Moved Startup Shutdown method Information

MSMQ Error Alert

New Flow Cell data has been updated. Information

New Lamp Serial Number has been updated. Information

New public search was created Information

Printed Report Information

Public search was updated. Information

Read Energy operation has been aborted Warning

Read Energy operation has been started Warning

Reading calibration values is completed Warning

Reinject Acquisition Information

Renamed Startup Shutdown method Information

Restore Summary Information

Result properties reorganization job error Alert

Result properties reorganization job finished Information

Result properties reorganization job started Information

Result properties reorganization job stopped Information

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Action Severity

Rolled back to previous Startup Shutdown method version Information

Sample Set Aborted Alert

Sample Set Completed Information

Sample Set Paused Information

Sample Set Resumed Information

Sample Set Started Information

Single Injection Completed Information

Solvent Low Level reached Warning

Start result properties reorganization job is scheduled Information

Structure index creation job finished Information

Structure index creation job started Information

Structure index creation job has failed Alert

Structure index creation job was stopped Information

Synonym type is set to unavailable Warning

The Acquisition List was aborted Information

The Acquisition List was cleared Information

The Acquisition List was moved down Information

The Acquisition List was moved up Information

The Acquisition List was paused Information

The Acquisition List was started Information

The Acquisition List was stopped Information

The Document was added to database Information

The document was deleted from item Information

The public search was deleted Information

The spectrum was deleted from item Information

Transport Engine error Alert

Unlocked Startup Shutdown method Information

Updated classifier Information

Updated modification Information

Updated tag Information

Validation failed Alert

Wavelengths not calibrated Warning

Z-axis Calibration Failed Warning

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Event properties

Data management event properties:

Action Severity

Abort Samplelist Notification Warning

Added note Alert

Added public view/search category Information

Added search keyword Information

Analysis created Information

Analysis saved Information

Analysis saved with edits Information

Analysis saved with faults Alert

Analysis saved with manual changes Alert

Analytical Data Export Error Alert

Analytical Data Export Error Summary Alert

Analytical Data Export Summary Information

Analytical task aborted Information

Analytical task created Information

Analytical task completed Information

Analytical task discarded Information

Analytical task state is invalid Alert

Analytical Task Submitted Information

Approved Qualification method Information

Assigned field Information

Copied Analysis method Information

Copied item to folder Information

Copied Qualification method Information

Created Analysis method Information

Created custom field Information

Created LIMS configuration Information

Created public search Information

Created public view Information

Created Qualification method Information

Created synonym group Information

Critical Error Alert

Critical Workflow Error Notification Alert

Data moved successfully Information

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Action Severity

Data remove from offline storage failed Alert

Data removed successfully from offline storage Alert

Delete Analysis Task Notification Alert

Deleted Analysis method Alert

Deleted custom field Information

Deleted data type Information

Deleted item Information

Deleted LIMS configuration Information

Deleted note Alert

Deleted public search Information

Deleted public view Information

Deleted public view/search category Information

Deleted Qualification method Alert

Deleted synonym group Information

Document Export Error Alert

Document Export Error Summary Alert

Document Export Summary Information

Export interrupted. Manual cleanup required. Alert

Exported folder Information

Exported items Information

Failed check data integrity Alert

Failed logon attempt Information

General Workflow Notification Information

Imported custom fields Information

Imported folder Information

Imported items Information

Location not accessible Alert

Locked custom field Information

Locked Analysis method Information

Locked Qualification method Information

Locked Qualification result Information

Modified Analysis method Information

Modified custom field Alert

Modified LIMS configuration Information

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Event properties

Action Severity

Modified note Alert

Modified public search Information

Modified public view Information

Modified public view/search category Information

Modified Qualification method Information

Modified synonym group Information

Moved Analysis method Information

Moved item to folder Information

Moved Qualification method Information

Moving data failed Alert

No available space Alert

No data at specified location Alert

Ownership taken (after discard) for Analysis Alert

Ownership taken (after save) for Analysis Information

Problem with export custom field file Alert

Problem with import custom field file Alert

Processing Error Alert

Qualification method unlocked Information

Removed search keyword Information

Renamed Analysis method Information

Renamed Qualification method Information

Restored data Information

Restored item failed Alert

Result export to LIMS Information

Revoked field Alert

Rolled back to previous Analysis method version Alert

Rolled back to previous Qualification method version Alert

Sample List Created Information

Sample List Modified Information

Save Warning Warning

Saved data type Information

Saved thumbnail Information

Search item types Information

System unlocked analysis Information

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Action Severity

Take ownership Qualification result Information

The offline storage configuration has empty UNC path Alert

The offline storage configuration is not active Alert

Unable to export file Alert

Unable to import file Alert

Unlocked Analysis method Information

Unlocked custom field Information

Unlocked Qualification method Information

Unlocked Qualification result Information

WorkFlow has finished Information

WorkFlow has started Information

Reporting event properties:

Action Severity

Annotated report Alert

Canceled signature sequence Information

Cannot find report for signature Warning

Cannot sign due to an unknown problem Warning

Copied Printer method Information

Copied Report Extraction method Information

Copied Report Template Information

Copied Signature method Information

Created Printer method Information

Created Report Extraction method Information

Created Report Object Information

Created Report Template Information

Created Report. Information

Created Signature method Information

Created Verification Report Information

Deleted Printer method Information

Deleted Report Extraction method Information

Deleted Report Object Information

Deleted Report Template Information

Deleted Signature method Warning

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Event properties

Action Severity

Duplicate signature Warning

Exported report Information

Generate Report Information

Incorrect signature Alert

Locked Printer method Information

Locked Report Extraction method Information

Locked Report Template Information

Locked Signature method Information

Modified Printer method Information

Modified Report Extraction method Information

Modified Report Object Information

Modified Report Template Information

Modified Signature method Information

Modified signature sequence Information

Moved Printer method Information

Moved Report Extraction method Information

Moved Report Template Information

Moved Signature method Information

No sign permission Information

No Signature Sequence found Information

Printed report Information

Rejected signature sequence Alert

Renamed Report Extraction method Information

Renamed Report Template Information

Renamed Signature method Information

Report Extraction method unlocked Information

Report is signed Information

Report is signed (single sign-off) Information

Report Object was moved from one folder to another Information

Report template unlocked Information

Report unavailable for signature Warning

Rolled back to previous Printer method version Information

Rolled back to previous Report Extraction method version Information

Rolled back to previous Report Template version Information

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Action Severity

Rolled back to previous Signature method version Information

Signature level due date expired Warning

Signature level due reminder Information

Signature method unlocked Information

Signature required Information

Signature sequence complete Information

Signature sequence missing Warning

Signed in another user’s session Alert

Started signature sequence Information

Unlocked Printer method Information

Unlocked Report Extraction method Information

Unlocked Report Template Information

Unlocked Signature method Information

Viewed report Information

Security and administration event properties:

Action Severity

Activated license Information

Assigned folder policy Information

Assigned license Information

Assigned user access Information

Changed user password Alert

Cloned data folder Information

Copied folder policy Information

Created comment Information

Created data folder Information

Created device folder Information

Created folder policy Information

Created meaning Information

Created offline storage configuration Information

Created reason Information

Created role Information

Created user Information

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Event properties

Action Severity

Database storage capacity increasedTip: Workstation only

Information

Deactivated license Information

Deleted comment Alert

Deleted data folder Alert

Deleted device folder Alert

Deleted folder policy Information

Deleted meaning Information

Deleted offline storage configuration Alert

Deleted reason Information

Deleted role Information

Deleted user Alert

Device configuration changed Alert

Device deleted Alert

Device moved Information

Duplicate credential error Warning

Failed logon attempt Information

Folder policy unlocked Information

License expiration warning Warning

License expired Alert

Low Disk Space Warning 10%Tip: Workstation only

Warning


Warning


Alert

Modified comment Information

Modified data folder status Information

Modified database password Alert

Modified device status Information

Modified folder policy Information

Modified global policy Information

Modified meaning Information

Modified offline storage configuration Information

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Action Severity

Modified reason Information

Modified role Information

Modified user access Information

Modified user information Information

Moved data folder Information

Moved device folder Information

New device registered Information

Package Added To Database Information

Package Failure On Device Alert

Package Modified On Device Information

Package Removed From Database Alert

Queued task canceled Information

Queued task stopped Information

Queued task submitted Information

Removed 1-time license Warning

Renamed data folder Information

Renamed device folder Information

Renamed folder policy Information

Reset password request Alert

Revoked folder policy Information

Revoked license Alert

Revoked user access Alert

Session locked Information

Session unlocked Information

Started folder policy inheritance Information

Started user access inheritance Information

Stopped folder policy inheritance Information

Stopped user access inheritance Information

Submission error Alert

Successful logon Information

Successfully logged out Information

System unlocked Administrator account Alert

Task schedule created Information

Task schedule disabled Information

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Event properties

Action Severity

Task schedule enabled Information

Task schedule updated Information

Unable to extend databaseTip: Workstation only

Alert

Unexpected error during DB Space evaluationTip: Workstation only

Alert

Upgraded instrument driver Alert

Upgraded UNIFI Alert

User account disabled Alert

User session closed Information

System event properties:

Action Severity

A major maintenance operation has been performed Information

Assigned qualification computer license Information

Assigned qualification instrument license Information

Assigned verification license Information

Cancelled qualification Alert

Created Event Filter Information

Created verification result Information

Deleted Event Filter Information

Deleted Events Alert

Deleted imported events Information

Deleted qualification result Alert

Deleted verification result Alert

Exported and Removed Events Alert

Exported events Warning

Imported Events Information

IQ Completed Information

Maintenance due date warning Warning

Maintenance overdue Warning

Maintenance record has been added for Qualification run Information

Maintenance record has been created Information

Maintenance record has been deleted Alert

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Action Severity

Maintenance record has been modified Information

Maintenance record has been removed for Qualification run Alert

Maintenance Scheduled Information

Modified diagnostic logging Information

Modified Event Filter Information

Modified Event Properties Information

Modified System information Information

Modified verification result status Information

OQ/PQ Completed Information

Problem With Export Event Log File Alert

Problem With Import Event Log File Alert

Qualification document imported Information

Qualification due date warning Warning

Qualification license revoked Alert

Qualification OQ continued with a failed IQ Alert

Qualification overdue Warning

Qualification related document has been added for Qualification run Information

Qualification related document has been removed for Qualification run Alert

Qualification result unlocked Information

Qualification run completed Information

Qualification run with unapproved qualification method Alert

Qualification run without training certificates Warning

Qualification Scheduled Information

Qualification started without an IQ Warning

Qualification test failed Alert

Qualification test result rerun Alert

Requalification recommended Information

Started qualification Information

Task exception Alert

The calibration date is overdue Warning

Thumbnail Creation Job Exception name Warning

Unexpected database exception occurred Alert

Unexpected exception Alert

UNIFI software update Information

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Event properties

Action Severity

Verification OQ result completed Information

Verification license revoked Alert

Verification result completed Information

Verification result completed with unapproved qualification method Alert

Verify files report generated Information

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UNIFI Installation and Configuration GuideTurn on MSMQ Server 55 Configure the power options 56 ......

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