ULTRA-FAST LOCALIZATION OF THE OPTIC DISC IN RETINAL FUNDUS IMAGES
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Transcript of ULTRA-FAST LOCALIZATION OF THE OPTIC DISC IN RETINAL FUNDUS IMAGES
ULTRA-FAST LOCALIZATION OF THE OPTIC DISC IN RETINAL
FUNDUS IMAGES
Ahmed E. Mahfouz
Dr. Ahmed S. Fahmy
Objectives
Project Goal:
Automatic Quantitative Analysis of Retinal Images
To achieve this goal, localization of retinal anatomical structures is required as an initial step
In this work, we propose an ultrafast localization of the Optic Disc (OD)
Optic Disc (OD) in Retina Images
Colored Retina Fundus Image, STARE Database
Optic Disc (OD)Fovea
Vessels Tree
Importance of OD localization
Localization of the Optic Disc (OD) is useful for:1. OD segmentation2. Locating other structures (e.g. fovea)3. Retinal image registration4. Identification of left & right eyes5. Tracking retinal vessels
OD Localization: Simple Threshold
Retina Fundus Image, STARE Database
Retina Fundus Image, STARE Database
OD Localization: Simple Threshold
OD Localization: sophisticated methods
Several OD localization methods are available:1. Vasculature convergence
A. Hoover et al. (2003), A. Youssif et al. (2008)
2. Geometrical model fitting M. Foracchia et al. (2004)
3. Template matching M. Lalonde et al. (2003)
4. Hough Transform F. ter Haar (2005)
Vasculature Convergence
1Aliaa Youssif, Atef Ghalwash, and Amr Ghoneim "Optic Disc Detection from Normalized digital Fundus Images by means of a Vessels' Direction Matched Filter" IEEE Trans. Medical Imaging, vol.27, no.1, pp. 11–18, Jan. 2008.
13.5 min
Original Image Contrast Enhancement
Histogram Equalization
Vessels ExtractionThinningFinal Result
Geometric Model Fitting
22 minOriginal Image Contrast
EnhancementHistogram Equalization
Vessels ExtractionModel FittingFinal Result2M. Foracchia, E. Grisan, A. Ruggeri, "Detection of Optic Disc in Retinal Images by Means of a Geometrical Model of Vessel Structure," IEEE Trans. Medical Imaging, vol. 23, no. 10, pp. 1189 – 1195, Oct. 2004.
Motivation
Although available techniques have high success rate, they are impractical due to their long computation times. OD localization is a preprocessing step that provides a seed
for further processing steps (segmentation, registration, …etc)
New fast localization techniques are required
Ultra-Fast Localization
Search Space Dimensionality Reduction
×
Ultra-Fast Localization
Horizontal Localization
Projection of the image features on the horizontal-axis
Projected Features:1) Difference
between vertical and horizontal edges (MAX)
2) Pixels’ intensity (MIN)
• Window height = image height• Window width = 2 X main vessel thickness
Ultra-Fast Localization
Ultra-Fast Localization
Vertical Localization
Projection of the image features on the vertical-axis
Projected Features:1) Summation of vertical and horizontal edges (MAX) 2) Pixels’ intensity (MAX)
Ultra-Fast Localization
Ultra-Fast Localization
Directionality of the vessels is described by their corresponding edges No matched filters are used for vessels extraction
The horizontal and vertical edge maps are acquired by applying a 3 X 1 gradient mask [1 0 -1] and its transpose to the retinal image
Evaluation
The new technique is evaluated using four publicly available databases (mostly used in literature):STARE, DRIVE, DIARETDB0, DIARETDB1
The new technique correctly located the OD in 321 images out of 340 images (94.4% accuracy)
The new technique achieved a computation time of 0.2 – 0.7 seconds depending on the image resolution
Results (success)
Results (failure)
This work has been accepted for presentation in 2009 IEEE Int. Conf. on Image Processing (ICIP’09)
Accuracy ImprovementIn the previous technique, only the following image
features have been used:1. Edge information of the retinal vessels.2. Pixels’ Intensity
In order to improve the accuracy of the technique, we propose using additional image features such as “Geometric Shape of the Optic Disc”
Accuracy Improvement
1. Construct a set of candidate locations 2 candidates
2. Define a scoring index for each candidate Index = Value of cand_H at this location
3. Weight each index with a factor Geometrical
features
cand_H
Accuracy Improvement
Evaluation
Technique Success Rate Computation Time
Without Improvement 94.4% 0.2 - 0.7 sec
With Improvement 97% 0.3 - 1 sec
Comparing the performance the proposed technique with/without the improvement step on the 4 databases (340 images)
This work has been accepted for presentation in the Int. Conf. of Medical Image Computing and Computer Assisted Intervention (MICCAI’09)
Conclusion A novel technique for fast and accurate OD localization
is developed.
The technique is based on reducing the search space dimensionality by projecting image features onto orthogonal axes.
The new technique is much faster (fraction of a second) than currently available techniques (few minutes)
Next Step Apply the new technique to Fluorescien
Angiograms (FA) of the retina (high contrast images)
Use the new idea of projecting the image features in other applications, such as:
1. Registration of retinal images 2. Determining the orientation of the retinal images
(left or right eye)
Thanks